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Pain Transmission in the Spinal Cord

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15 Questions

In which lamina of the dorsal horn do nociceptive axons synapse with second-order neurons?

Lamina I, II, and V

What neurotransmitter is released by moderate pain axons in the dorsal horn?

Glutamate

What is the characteristic of the action of neurotransmitters released by stronger pain axons?

Slow and sustained

What is the role of ATP in pain transmission in the dorsal horn?

Facilitating pain transmission

What is the primary function of nociceptive axons in the dorsal horn?

Transmitting pain signals

What is the primary neurotransmitter released by both moderate and stronger pain axons?

Glutamate

What is the characteristic of the action of neurotransmitters released by moderate pain axons?

Fast and brief

Which of the following lamina in the dorsal horn does not receive synapses from nociceptive axons?

Lamina III

What is the distinguishing feature of stronger pain axons compared to moderate pain axons?

Release of glutamate and substance P

What is the function of substance P in pain transmission?

Enhancing the strength of pain signals

What is the primary difference in neurotransmitter release between moderate and stronger pain axons?

Release of substance P

In which lamina of the spinal cord do axons release glutamate and substance P?

Lamina I, II, and V

What is the relationship between the type of pain and the speed of neurotransmitter action?

Moderate pain axons have faster action

What is the common neurotransmitter released by both moderate and stronger pain axons?

Glutamate

Which of the following is a characteristic of stronger pain axons?

Slower, sustained actions

Study Notes

Pain Transmission in the Spinal Cord

  • Nociceptive axons synapse with second-order neurons in lamina I, II, and V of the dorsal horn in the spinal cord
  • Transmission of moderate pain involves the release of glutamate by axons
  • Transmission of stronger pain involves the release of both glutamate and substance P (and ATP) by axons
  • The action of glutamate is fast
  • The action of substance P (and ATP) is slower and more sustained

Pain Transmission in the Spinal Cord

  • Nociceptive axons synapse with second-order neurons in lamina I, II, and V of the dorsal horn in the spinal cord
  • Transmission of moderate pain involves the release of glutamate by axons
  • Transmission of stronger pain involves the release of both glutamate and substance P (and ATP) by axons
  • The action of glutamate is fast
  • The action of substance P (and ATP) is slower and more sustained

Pain Transmission in the Spinal Cord

  • Nociceptive axons synapse with second-order neurons in lamina I, II, and V of the dorsal horn in the spinal cord
  • Transmission of moderate pain involves the release of glutamate by axons
  • Transmission of stronger pain involves the release of both glutamate and substance P (and ATP) by axons
  • The action of glutamate is fast
  • The action of substance P (and ATP) is slower and more sustained

This quiz covers the transmission of pain signals in the spinal cord, including the role of nociceptive axons, glutamate, and substance P.

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