Podcast
Questions and Answers
What is the primary function of nociceptors in the pain perception pathway?
What is the primary function of nociceptors in the pain perception pathway?
- To regulate the release of endogenous opioid peptides
- To transduce noxious stimuli into electrical signals (correct)
- To transmit innocuous mechanical stimuli
- To modulate the affective component of pain
What is the term for the heightened response to a stimulus that is normally algesic?
What is the term for the heightened response to a stimulus that is normally algesic?
- Allodynia
- Hyperalgesia (correct)
- Nociception
- Analgesia
What type of ion channels are involved in the detection of painful stimuli?
What type of ion channels are involved in the detection of painful stimuli?
- Voltage-dependent potassium channels
- Voltage-dependent calcium channels
- Ligand-gated ion channels
- Voltage-dependent sodium channels (correct)
Which type of pain is characterized by a sustained response to injury, even after the initial stimulus has resolved?
Which type of pain is characterized by a sustained response to injury, even after the initial stimulus has resolved?
What is the result of the activation of immune cells in inflammatory pain?
What is the result of the activation of immune cells in inflammatory pain?
What is the primary function of the opioid system in the context of pain perception?
What is the primary function of the opioid system in the context of pain perception?
What is the consequence of nociceptor sensitization in inflammatory pain?
What is the consequence of nociceptor sensitization in inflammatory pain?
What type of agents are involved in the inflammatory cascade?
What type of agents are involved in the inflammatory cascade?
What is the term for the response to a stimulus that is not normally algesic?
What is the term for the response to a stimulus that is not normally algesic?
What is the classification of Ab fibers, which are responsible for transmitting information about posture, motion, and position as well as innocuous mechanical and thermal stimuli?
What is the classification of Ab fibers, which are responsible for transmitting information about posture, motion, and position as well as innocuous mechanical and thermal stimuli?
What is the effect of NSAIDs on inflammatory pain?
What is the effect of NSAIDs on inflammatory pain?
Which of the following opioid receptors is primarily responsible for mediating analgesia via spinal mechanisms?
Which of the following opioid receptors is primarily responsible for mediating analgesia via spinal mechanisms?
What is the primary function of the spinoreticular tract in pain perception?
What is the primary function of the spinoreticular tract in pain perception?
Which of the following is an endogenous analgesic peptide that is involved in the regulation of pain and mood?
Which of the following is an endogenous analgesic peptide that is involved in the regulation of pain and mood?
What is the mechanism of action of opioids on neurons in the spinal cord?
What is the mechanism of action of opioids on neurons in the spinal cord?
Which of the following opioids is known for its high abuse liability and potential for respiratory depression?
Which of the following opioids is known for its high abuse liability and potential for respiratory depression?
What is the primary difference between opioid agonists and antagonists?
What is the primary difference between opioid agonists and antagonists?
Which of the following opioid receptors is responsible for mediating the affective and alertive aspects of pain?
Which of the following opioid receptors is responsible for mediating the affective and alertive aspects of pain?
What is the primary function of the descending nociceptive pathways in pain perception?
What is the primary function of the descending nociceptive pathways in pain perception?
Which of the following is a characteristic of opioids that is relevant to their abuse liability?
Which of the following is a characteristic of opioids that is relevant to their abuse liability?
What is the primary mechanism of action of opioid antagonists?
What is the primary mechanism of action of opioid antagonists?
