Packed Cell Volume (Hematocrit) and Red Blood Cells Quiz

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Questions and Answers

What is the packed cell volume (hematocrit) a measure of?

Volume of plasma per 100 ml of blood

Total volume of blood in the body

Volume of blood cells per 100 ml of blood (correct)

Volume of platelets per 100 ml of blood

What is the average percentage of blood volume made up by the plasma?

40%

55% (correct)

60%

45%

What is the average number of RBCs per cubic millimeter in healthy men?

4,700,000 (±300,000)

4,400,000 (±300,000)

5,200,000 (±300,000) (correct)

6,000,000 (±300,000)

What is the average number of RBCs per cubic millimeter in women?

4,700,000 (±300,000) Signup and view all the answers

What is the average lifespan of RBCs?

120 days Signup and view all the answers

From where are RBCs derived?

Pluripotential hematopoietic stem cell in the bone marrow Signup and view all the answers

What causes growth induction and production of increased numbers of erythrocytes?

Exposure of blood to low oxygen for a long time Signup and view all the answers

What is the first step in the procedure for measuring packed cell volume?

Clean the thumb with alcohol soaked cotton and puncture it Signup and view all the answers

What should be done after allowing the blood to enter the capillary tube in the procedure for measuring packed cell volume?

Seal one end of the capillary tube by sealing clay Signup and view all the answers

What happens to the shape of RBCs as they squeeze through capillaries?

The shape can change remarkably Signup and view all the answers

What part of blood reflects the volume of red blood cells?

Packed cell volume (hematocrit) Signup and view all the answers

Which condition is characterized by an increase in the volume of P.C.V above the reference range?

Burn Injury Signup and view all the answers

What can cause microcytic hypochromic anemia?

Chronic blood loss Signup and view all the answers

Which condition is associated with megaloblastic anemia?

Vitamin B12 deficiency Signup and view all the answers

What causes primary polycythemias?

Acquired or inherited genetic mutations Signup and view all the answers

Which condition is associated with hemolytic anemia?

G6PD deficiency Signup and view all the answers

What type of anemia results from a lack of functioning bone marrow?

Aplastic Anemia Signup and view all the answers

Which condition can cause a decrease in the volume of P.C.V?

Pregnancy Signup and view all the answers

What can result from exposure to high-dose radiation or chemotherapy for cancer treatment?

Aplastic Anemia Signup and view all the answers

Which condition is caused by vitamin B12 & folic acid deficiency?

Megaloblastic Anemia Signup and view all the answers

What is the term for a decrease in the volume of P.C.V below the normal range?

Anemia Signup and view all the answers

Which condition results in an increase in hematocrit, hemoglobin, or RBC?

Acquired or inherited genetic mutations Signup and view all the answers

Study Notes

Red Blood Cells and Hematocrit

Packed cell volume (hematocrit) measures the proportion of blood volume made up by red blood cells (RBCs).
Plasma makes up approximately 55% of blood volume.
Healthy men have an average of 5.4 million RBCs per cubic millimeter.
Healthy women have an average of 4.8 million RBCs per cubic millimeter.
The average lifespan of RBCs is 120 days.
RBCs are derived from stem cells in the bone marrow.
Growth induction and production of increased numbers of erythrocytes are caused by erythropoietin (EPO).

Measuring Packed Cell Volume

The first step in measuring packed cell volume is to add anticoagulant to the blood sample.
After allowing the blood to enter the capillary tube, the tube should be sealed at one end and centrifuged.

Characteristics of RBCs

RBCs change shape to squeeze through capillaries.
The hematocrit (packed cell volume) reflects the volume of red blood cells.

Polycythemia is characterized by an increase in packed cell volume above the reference range.
Microcytic hypochromic anemia can be caused by iron deficiency.
Megaloblastic anemia is associated with vitamin B12 and folic acid deficiency.
Primary polycythemias are caused by genetic mutations.
Hemolytic anemia is associated with premature destruction of RBCs.
Aplastic anemia results from a lack of functioning bone marrow.
Anemia can cause a decrease in packed cell volume.
Bone marrow failure can result from exposure to high-dose radiation or chemotherapy for cancer treatment.
Anemia can also be caused by vitamin B12 and folic acid deficiency.
Anemia is characterized by a decrease in packed cell volume below the normal range.
Polycythemia results in an increase in hematocrit, hemoglobin, or RBCs.

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Description

Test your knowledge about packed cell volume (hematocrit) and red blood cells (erythrocytes) in this quiz. Learn about the volume of blood made by blood cells and their characteristics.