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Questions and Answers
What is the main function of the p53 protein?
What is the main function of the p53 protein?
Which gene encodes the p53 tumor suppressor protein in humans?
Which gene encodes the p53 tumor suppressor protein in humans?
What is the role of p53 in controlling the cell cycle?
What is the role of p53 in controlling the cell cycle?
What is the significance of p53 mutations in human cancers?
What is the significance of p53 mutations in human cancers?
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How does p53 respond to irreparable DNA damage?
How does p53 respond to irreparable DNA damage?
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Which family includes p53, p63, and p73?
Which family includes p53, p63, and p73?
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What is the main function of p53 in response to cellular insults?
What is the main function of p53 in response to cellular insults?
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What is the primary reason for p53 being referred to as the guardian of the genome?
What is the primary reason for p53 being referred to as the guardian of the genome?
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What was the significance of the discovery of genes p63 and p73 in relation to p53?
What was the significance of the discovery of genes p63 and p73 in relation to p53?
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What is the role of MDM-2, a p53-activated gene?
What is the role of MDM-2, a p53-activated gene?
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What is the function of MDM-X in relation to MDM-2?
What is the function of MDM-X in relation to MDM-2?
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What is the primary function of ATM protein kinase CHK2?
What is the primary function of ATM protein kinase CHK2?
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How do stress signals such as UV and genotoxic drugs impact the activation of p53?
How do stress signals such as UV and genotoxic drugs impact the activation of p53?
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What is the result of increased p53 activity?
What is the result of increased p53 activity?
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What is the function of ATR kinase CHK1 after UV irradiation?
What is the function of ATR kinase CHK1 after UV irradiation?
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What is the primary role of p63 and p73 in relation to tumor suppression?
What is the primary role of p63 and p73 in relation to tumor suppression?
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What is the primary function of p53 in response to DNA damage?
What is the primary function of p53 in response to DNA damage?
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What is the role of p53 in controlling the integrity and correctness of processes in individual cells and the organism as a whole?
What is the role of p53 in controlling the integrity and correctness of processes in individual cells and the organism as a whole?
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What is the main function of the p53 protein?
What is the main function of the p53 protein?
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What are the members of the p53 family?
What are the members of the p53 family?
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What is the significance of p53 mutations in human cancers?
What is the significance of p53 mutations in human cancers?
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How does p53 ensure the genetic identity of cells and prevent the selection of abnormal cells?
How does p53 ensure the genetic identity of cells and prevent the selection of abnormal cells?
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What are the names of the two genes discovered almost 20 years after p53?
What are the names of the two genes discovered almost 20 years after p53?
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What is the primary role of p53 in response to cellular insults?
What is the primary role of p53 in response to cellular insults?
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What is the result of increased p53 activity?
What is the result of increased p53 activity?
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What is the role of MDM-2, a p53-activated gene?
What is the role of MDM-2, a p53-activated gene?
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What is the primary function of the p53 protein?
What is the primary function of the p53 protein?
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What is the function of MDM-X in relation to MDM-2?
What is the function of MDM-X in relation to MDM-2?
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What is the significance of p53 mutations in human cancers?
What is the significance of p53 mutations in human cancers?
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What is the primary role of p63 and p73 in relation to tumor suppression?
What is the primary role of p63 and p73 in relation to tumor suppression?
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What is the primary reason for p53 being referred to as the guardian of the genome?
What is the primary reason for p53 being referred to as the guardian of the genome?
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Which family includes p53, p63, and p73?
Which family includes p53, p63, and p73?
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