Oxybutynin Flashcards

Study Notes

Oxybutynin Overview

Brand name is Ditropan; the generic name is Oxybutynin.

Indications

Effective for bladder instability due to uninhibited or reflex neurogenic bladder.
Treats overactive bladder characterized by urge incontinence, urgency, and frequency.

Dosing Guidelines

For bladder instability: Administer one 5 mg immediate release (IR) tablet 2-3 times daily, with a maximum of 20 mg per day.
For overactive bladder: Start with 5 mg extended release (ER) tablet daily; may increase weekly to a maximum of 30 mg.

Available Strengths and Formulations

Tablets available in 5 mg strength.
Extended release tablets come in 5 mg, 10 mg, and 15 mg.
Syrup formulation: 5 mg/5 mL.
Also offered as a topical patch.

Medication Class

Classified as a urinary bladder modifier.

Pharmacology

Works by inhibiting muscarinic acetylcholine action on smooth muscle.
Relaxes bladder smooth muscle, reducing urgency, frequency, urinary leakage, and dysuria.

Drug Interactions

Can reduce the effectiveness of phenothiazines and haloperidol.
Risk of tardive dyskinesia when combined with haloperidol.
May exhibit additive effects with other anticholinergic agents.
No medications classified as risk X/D.

Side Effects

Common side effects include dry mouth and drowsiness.
Other adverse effects: nausea, confusion, agitation, blurred vision, diarrhea.

Contraindications

Not suitable for patients with uncontrolled narrow-angle glaucoma, urinary retention, gastric retention, or impaired hepatic/renal function.
Caution in those with gastrointestinal obstruction, ulcerative colitis, intestinal atony, myasthenia gravis.
Pregnant patients fall under Category B.
Risk of heat prostration in hot environments.

Patient Counseling

Advise avoidance of prolonged exposure to heat.
Inform about potential drowsiness; caution when using machinery or requiring mental focus.
Store medication in a cool, dry place, away from sunlight and children.
If a dose is missed, take as soon as possible but skip if near the next scheduled dose; do not double doses.
Contact a physician if side effects are severe or persistent.
Instruct to swallow ER tablets whole; do not crush, split, or chew.
ER tablet shells may appear intact in stool.

Description

Test your knowledge on Oxybutynin with these flashcards. The quiz covers brand names, generic names, indications, and dosing information related to this medication. Perfect for students and healthcare professionals looking to enhance their understanding of pharmacology.