Questions and Answers
What is a key point regarding Oxcarbazepine (Trileptal)?
What drug classifications does Oxcarbazepine (Trileptal) belong to?
What is one indication for the use of Oxcarbazepine (Trileptal)?
Bipolar disorder (mania)
Which of the following are side effects of Oxcarbazepine (Trileptal)?
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What is one nursing responsibility when administering Oxcarbazepine (Trileptal)?
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What is the action mechanism of Oxcarbazepine (Trileptal)?
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Oxcarbazepine (Trileptal) is contraindicated in cases of hypersensitivity.
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Which conditions require caution when using Oxcarbazepine (Trileptal)?
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What does Oxcarbazepine (Trileptal) decrease the effectiveness of?
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Study Notes
Oxcarbazepine (Trileptal) Overview
- Oxcarbazepine, marketed as Trileptal, is associated with an elevated risk of suicidality.
- Classified as a carbamazepine analogue, functioning as a mood stabilizer and anticonvulsant.
Indications
- Primarily indicated for the treatment of bipolar disorder, specifically for managing mania.
Side Effects
- Common side effects include:
- Suicidal thoughts
- Dizziness and headaches
- Cognitive impairment
- Visual disturbances such as decreased vision, diplopia, and nystagmus
- Gastrointestinal issues including abdominal pain, dyspepsia, nausea, and vomiting
- Additional effects like thirst, acne, rash, urticaria, and hypothyroidism
- Risk of hyponatremia, ataxia, gait disturbances, tremors
- Severe reactions such as Stevens Johnson syndrome and lymphadenopathy.
Nursing Responsibilities
- Routine monitoring of ECG, electrolyte levels, and sodium concentration is essential.
Mechanism of Action
- Works by blocking sodium channels in neural membranes.
- Stabilizes overactive neural activity by inhibiting repetitive neuronal firing and reducing synaptic impulse propagation.
Contraindications
- Not suitable for individuals with hypersensitivity to the drug.
- Avoid use during lactation.
Cautionary Considerations
- Suicidality risk necessitates careful monitoring.
- Use with caution in patients with renal or severe hepatic impairment.
Drug Interactions
- May decrease the effectiveness of hormonal contraceptives and medications like felodipine, isradipine, nicardipine, nifedipine, and cyclosporine.
- Increases central nervous system (CNS) depression when combined with CNS depressants.
- Other mood stabilizers may reduce the effectiveness of oxcarbazepine.
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Description
Test your knowledge about Oxcarbazepine, also known as Trileptal, with these flashcards. Explore key points including drug classification, indications, and potential side effects. Perfect for students and professionals in the medical field.
