Osteoporosis Treatment Options
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Questions and Answers

What is the patient's height in centimeters?

  • 172cm
  • 175cm
  • 170cm (correct)
  • 168cm

What is the patient's weight in kilograms?

  • 50 kg
  • 58 kg
  • 54 kg (correct)
  • 60 kg

Why was the patient taking a nonsteroidal anti-inflammatory drug (NSAID)?

  • To relieve occasional back pain and stiffness (correct)
  • To treat gastroesophageal reflux disease
  • To improve her diet
  • To prevent osteoporosis

What is the patient's family history regarding osteoporosis?

<p>Her mother and aunt have sustained osteoporotic fractures (A)</p> Signup and view all the answers

What is the patient's T score at the spine?

<p>-1.5 (A)</p> Signup and view all the answers

Why was the patient referred for BMD testing?

<p>According to the recommendations of the National Osteoporosis Foundation (C)</p> Signup and view all the answers

What is indicated by her T-score?

<p>Osteopenia (A)</p> Signup and view all the answers

What is the purpose of the FRAX tool?

<p>To assess the 10-year probability of hip and major osteoporotic fracture (C)</p> Signup and view all the answers

Why is ibandronate not a suitable drug to manage her case?

<p>It is only effective in reducing spine fracture risk (B)</p> Signup and view all the answers

What is a risk factor for osteoporosis mentioned in the text?

<p>Poor nutrition and low calcium intake (C)</p> Signup and view all the answers

What is considered a high fracture risk according to FRAX?

<p>≥ 3% for hip or ≥ 20% major OPF (A)</p> Signup and view all the answers

What is a potential result of FRAX assessment in this patient?

<p>High fracture risk (C)</p> Signup and view all the answers

What is typically used to evaluate bone resorption during antiresorptive therapy?

<p>Serum C-telopeptide of type I collagen (CTX) (B)</p> Signup and view all the answers

What is the typical duration of treatment before considering a drug holiday?

<p>3 years (A)</p> Signup and view all the answers

Why is a drug holiday recommended after long-term bisphosphonate therapy?

<p>To minimize the risk of osteonecrosis of the jaw and Atypical femur fractures (A)</p> Signup and view all the answers

What is the effect of bisphosphonates on bone density after discontinuation?

<p>The increased BMD is sustained for a prolonged period (C)</p> Signup and view all the answers

What is the purpose of measuring bone turnover markers (BTMs) at 3-6 months after initiation of treatment?

<p>To evaluate the efficacy of antiresorptive therapy (A)</p> Signup and view all the answers

What is the recommended drug class for a patient with high fracture risk according to 2020 AACE/ACE guidelines?

<p>Bisphosphonates and monoclonal antibodies (C)</p> Signup and view all the answers

Why was the patient prescribed I.V bisphosphonates (zoledronic acid) instead of oral bisphosphonates?

<p>Because the patient had GERD and oral bisphosphonates would worsen the condition (C)</p> Signup and view all the answers

What is a common adverse effect of I.V bisphosphonates?

<p>Fever and muscle aches (flu-like symptoms) (A)</p> Signup and view all the answers

What is a possible way to evaluate therapeutic outcomes in patients with high fracture risk?

<p>By asking patients about possible fracture symptoms (C)</p> Signup and view all the answers

How often can central DXA BMD measurements be obtained for monitoring bone loss and treatment response?

<p>Every 1 to 2 years (C)</p> Signup and view all the answers

What is another possible adverse effect of I.V bisphosphonates?

<p>Osteonecrosis of the jaw (ONJ) (D)</p> Signup and view all the answers

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