Questions and Answers
What is the risk of medication-related osteonecrosis of the jaw (MRONJ) associated with parenteral administration of bisphosphonates?
1% to 10%
What is the most common reason for the prescription of bisphosphonates?
Osteoporosis
What is the relationship between alendronate (Fosamax) and the incidence of osteonecrosis?
Alendronate is related to a higher incidence of osteonecrosis
What percentage of patients reported pain with bone exposure after bisphosphonate treatment?
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What does a CTX value of less than 100 pg/mL represent?
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What did the ADA state about the reliability of CTX testing and drug holidays for predicting and mitigating the risk of BRONJ?
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According to the American Association of Oral and Maxillofacial Surgeons position paper, when should the clinician consider discontinuing the use of oral bisphosphonates before and after elective invasive dental surgery?
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What does the ADA recommend regarding staging of non-critical dental treatment for patients on bisphosphonates?
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What does the text recommend regarding the initiation of bisphosphonate therapy for patients requiring IV bisphosphonates?
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How may MRONJ development be reduced for patients on bisphosphonates?
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