Osteopetrosis (Marble Bone Disease) Quiz
40 Questions
0 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the characteristic radiographic feature of Osteopetrosis?

  • Decreased skeletal density
  • Presence of bone cysts
  • Increased skeletal density with a marble-like appearance (correct)
  • Widening of skull foramina

    • What is the age range when Cherubism typically presents?

  • 5 to 10 years of age
  • 1 to 2 years of age
  • 10 to 15 years of age
  • 2 to 5 years of age (correct)

    • What is the oral manifestation of Osteopetrosis?

  • Increased risk of dental caries
  • Absence of osteoclasts
  • Early exfoliation of teeth
  • Failure of tooth eruption (correct)

    • What is the complication of Osteopetrosis that affects the hematopoietic system?

    <p>All of the above</p> Signup and view all the answers

    What is the differential diagnosis of Osteopetrosis?

    <p>All of the above</p> Signup and view all the answers

    What is the primary reason for the blue sclera color in Osteogenesis Imperfecta Type I?

    <p>Reduced collagen content in the sclera allowing pigmented choroid to show through</p> Signup and view all the answers

    Which of the following is a characteristic radiographic feature of Osteogenesis Imperfecta?

    <p>Bowing of long bones</p> Signup and view all the answers

    What is the primary difference between Osteogenesis Imperfecta and Osteopetrosis?

    <p>Bone density</p> Signup and view all the answers

    What is the outcome for most patients with Osteogenesis Imperfecta Type II?

    <p>Death before 4 weeks of age</p> Signup and view all the answers

    What is the underlying cause of Osteopetrosis?

    <p>Failure of osteoclastic bone resorption</p> Signup and view all the answers

    Which of the following congenital bone diseases is characterized by brittle bone that is prone to fracture?

    <p>Osteogenesis imperfecta</p> Signup and view all the answers

    What is the primary cause of bone fragility in osteogenesis imperfecta?

    <p>Mutation in COL1A1 and COL1A2 genes</p> Signup and view all the answers

    Which type of osteogenesis imperfecta is the most common and mildest form?

    <p>Type I</p> Signup and view all the answers

    What is the characteristic feature of osteopetrosis?

    <p>Abnormal bone density</p> Signup and view all the answers

    Which of the following is NOT a type of hereditary bone disease affecting endochondral bone?

    <p>Osteoporosis</p> Signup and view all the answers

    What is the primary consequence of osteoporosis in the maxilla and/or mandible?

    <p>Enhanced bone fragility</p> Signup and view all the answers

    Which congenital bone disorder is characterized by brittle bones that are prone to fracture?

    <p>Osteogenesis Imperfecta</p> Signup and view all the answers

    What is the most significant factor in the prevention of osteoporosis?

    <p>Regular exercise</p> Signup and view all the answers

    Which of the following is a characteristic of osteopetrosis?

    <p>Impaired bone remodeling</p> Signup and view all the answers

    What is the primary focus of the lecture on osteoporosis and congenital bone disease?

    <p>Clinical and histopathological features of congenital bone disease</p> Signup and view all the answers

    What is the primary genetic defect that leads to Cherubism?

    <p>Mutations in the RUNX2 gene</p> Signup and view all the answers

    What is a characteristic oral manifestation of Cleidocranial Dysplasia?

    <p>All of the above</p> Signup and view all the answers

    What is a common finding in radiographic examination of Cherubism patients?

    <p>Bilateral, multilocular radiolucencies</p> Signup and view all the answers

    What is a characteristic feature of teeth in Cleidocranial Dysplasia patients?

    <p>Enamel hypoplasia</p> Signup and view all the answers

    What is a common finding in the maxilla of Cleidocranial Dysplasia patients?

    <p>Narrow and V-shaped with high arched palate</p> Signup and view all the answers

    What is the primary mechanism by which glucocorticoids contribute to bone loss?

    <p>Stimulation of osteoclastic activity</p> Signup and view all the answers

    Which of the following is a consequence of mutation in COL1A1 and COL1A2 genes?

    <p>Deficiency in type 1 collagen</p> Signup and view all the answers

    Heavy alcohol consumption can lead to bone loss and fracture due to which of the following mechanisms?

    <p>Increased risk of falling and poor nutrition</p> Signup and view all the answers

    Which of the following medications is used to treat osteoporosis by inhibiting osteoclastic function and differentiation?

    <p>Bisphosphonates</p> Signup and view all the answers

    Which of the following is a characteristic feature of osteoporosis?

    <p>Thin trabeculae disconnected from each other</p> Signup and view all the answers

    What is the primary cause of achondroplasia?

    <p>Mutation in fibroblast growth factor 3 (FGFR3) on chromosome 4</p> Signup and view all the answers

    What is the characteristic feature of the axial skeleton in achondroplasia?

    <p>Normal development</p> Signup and view all the answers

    What is the oral manifestation of achondroplasia?

    <p>Delayed dental development</p> Signup and view all the answers

    What is the definition of osteoporosis?

    <p>A condition characterized by low bone mass</p> Signup and view all the answers

    What is the consequence of osteoporosis?

    <p>Increased morbidity and mortality risks</p> Signup and view all the answers

    What is the impact of achondroplasia on intelligence?

    <p>No impairment</p> Signup and view all the answers

    What is the characteristic feature of the extremities in achondroplasia?

    <p>Short and thick</p> Signup and view all the answers

    What is the consequence of delayed dental development in achondroplasia?

    <p>Delayed eruption of primary and permanent teeth</p> Signup and view all the answers

    What is the characteristic feature of the maxilla in achondroplasia?

    <p>Hypoplasia</p> Signup and view all the answers

    What is the type of malocclusion associated with achondroplasia?

    <p>Class III</p> Signup and view all the answers

    More Like This

    Use Quizgecko on...
    Browser
    Open
    Browser
    Browser