Oral Laxatives
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Questions and Answers

How do stimulant laxatives work?

  • By decreasing intestinal secretion, increasing water reabsorption, and inhibiting colon peristalsis
  • By increasing stool weight and consistency
  • By stimulating water secretion at bowel lumen
  • By increasing intestinal secretion, reducing water reabsorption, and stimulating colon peristalsis (correct)

    • What is the nature of stool softeners?

  • Synthetic in nature, with a bulking effect in the colon
  • Chemical in nature, with a dehydrating effect in the colon
  • Mineral in nature, with a lubricating effect throughout the intestine (correct)
  • Herbal in nature, with a stimulating effect on the rectum

    • How do osmotic laxatives work?

  • By reducing water reabsorption at bowel lumen
  • By inhibiting colon peristalsis
  • By stimulating water secretion at bowel lumen (correct)
  • By increasing stool weight and consistency

    • What is the working mechanism of fleet enema?

    <p>Releasing bound water from stool and stimulating rectal and distal peristalsis</p> Signup and view all the answers

    What is the action time of colace?

    <p>24-72 hours</p> Signup and view all the answers

    What is the primary shortcoming of the combination of Opioid and naloxone for OIC management?

    <p>It titrates opioid effect and causes opioid withdrawal symptoms</p> Signup and view all the answers

    What distinguishes Methylnaltrexone from the combination of Opioid and naloxone in OIC management?

    <p>It does not affect analgesia as it does not cross the blood-brain barrier</p> Signup and view all the answers

    What is the drawback of using Methylnaltrexone for OIC management?

    <p>It has to be given by subcutaneous route and is expensive</p> Signup and view all the answers

    How does Naloxone work in the management of OIC?

    <p>As a competitive antagonist of opioid receptors inside and outside the Central Nervous System</p> Signup and view all the answers

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