5 Questions
What influences the passive transfer of a drug from a region of higher concentration to a region of lower concentration?
The size of the drug molecules
Which orally administered dosage form has the greatest absorption?
Tablets
The sodium–potassium pump is an example of which transport mechanism?
Active carrier-mediated transport
Which orally administered dosage form has the slowest absorption?
Enteric-coated tablets
What is the purpose of enteric coatings on drugs?
Prevent decomposition of chemically sensitive drugs by gastric secretions
Study Notes
Passive Transfer of Drugs
- The passive transfer of a drug from a region of higher concentration to a region of lower concentration is influenced by concentration gradients.
Drug Absorption
- Solid dosage forms, such as tablets and capsules, have the greatest absorption when administered orally.
- Liquid dosage forms, such as solutions and suspensions, have the slowest absorption when administered orally.
Transport Mechanisms
- The sodium–potassium pump is an example of active transport, which involves the use of energy to move molecules against their concentration gradient.
Enteric Coatings
- Enteric coatings on drugs are used to resist the acidic environment of the stomach and release the drug in the intestine, where the pH is more neutral.
Test your knowledge of pharmacodynamics and pharmacokinetics with this quiz on drug absorption. Answer questions about different orally administered dosage forms and their impact on absorption rates.
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