Optics and Vision Science Quiz
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Questions and Answers

What is the wavelength range of visible light?

  • 300-400nm
  • 400-700nm (correct)
  • 700-800nm
  • 800-900nm
  • What refractive index (RI) value indicates the highest light reflection within the eye?

  • 1.40 (correct)
  • 1.34
  • 1.38
  • 1.33
  • Which type of lens is required for correcting hyperopia?

  • Cylindrical lens
  • Concave lens
  • Convex lens (correct)
  • Bifocal lens
  • In the case of astigmatism, what causes the different focal distances in one plane?

    <p>Uneven curvature of the cornea (C)</p> Signup and view all the answers

    What is the power of the eye if it is considered a single lens?

    <p>+59D (D)</p> Signup and view all the answers

    What is not a common cause of myopia?

    <p>Short eyeball (A)</p> Signup and view all the answers

    What happens to the image when accommodation fails?

    <p>The image appears blurred (D)</p> Signup and view all the answers

    What correction is typically recommended for keratoconus?

    <p>Contact lenses (C)</p> Signup and view all the answers

    What protein is associated with rhodopsin in the process of phototransduction?

    <p>Scotopsin (C)</p> Signup and view all the answers

    During which stage of phototransduction does metarhodopsin II stimulate phosphodiesterase?

    <p>Stage II (D)</p> Signup and view all the answers

    What happens to sodium channels during the light phase of phototransduction?

    <p>They close (C)</p> Signup and view all the answers

    Which of the following statements is true about rod cells compared to cone cells?

    <p>Rods are more sensitive to light than cones. (A)</p> Signup and view all the answers

    What characterizes the ability of cones in terms of adaptation to darkness?

    <p>Cones adapt rapidly to darkness. (A)</p> Signup and view all the answers

    Which type of pigment is responsible for the red color in human vision?

    <p>Photopsin (B)</p> Signup and view all the answers

    What is primarily responsible for the perception of movement in light?

    <p>Amacrine cells (D)</p> Signup and view all the answers

    In the dark, what is the state of the photoreceptor's permeability to sodium?

    <p>Highly permeable (D)</p> Signup and view all the answers

    What is the primary function of the aqueous humor?

    <p>To maintain intra-ocular pressure (D)</p> Signup and view all the answers

    Which of the following cells is NOT a type of cell found in the retina?

    <p>Mueller cells (D)</p> Signup and view all the answers

    What is the typical mean intra-ocular pressure (IOP) value in mmHg?

    <p>15 mmHg (B)</p> Signup and view all the answers

    What is the pathway for aqueous humor drainage after leaving the anterior chamber?

    <p>Anterior chamber -&gt; Pupil -&gt; Schlemm canal (D)</p> Signup and view all the answers

    What change occurs in the lens when the ciliary muscles contract during accommodation?

    <p>The lens becomes more convex and spherical. (A)</p> Signup and view all the answers

    Which of the following structures provides blood supply to the outer third of the retina?

    <p>Choroid layer (D)</p> Signup and view all the answers

    Which anatomical structure is responsible for initiating the accommodation reflex?

    <p>Edinger-Westphal nucleus (D)</p> Signup and view all the answers

    What is the role of horizontal cells in the retina?

    <p>To inhibit signals from photoreceptors (C)</p> Signup and view all the answers

    What is the effect of aging on the power of accommodation in the eye?

    <p>It decreases due to lens hardening and decreased elasticity. (C)</p> Signup and view all the answers

    What contributes to the high visual acuity of the fovea?

    <p>Higher density of cones and absence of blood vessels (A)</p> Signup and view all the answers

    What is the maximum amount of light that can enter the eye when the pupil is fully dilated?

    <p>64 (A)</p> Signup and view all the answers

    Increased intra-ocular pressure can lead to which common eye condition?

    <p>Glaucoma (A)</p> Signup and view all the answers

    Which nerve fibers are responsible for pupil constriction?

    <p>Parasympathetic nervous system fibers (D)</p> Signup and view all the answers

    What is the relationship between pupil diameter and the amount of light entering the eye?

    <p>The amount of light is proportional to the square of the diameter. (B)</p> Signup and view all the answers

    What is true about the refractive power of the lens when there is no accommodation?

    <p>The lens is flat and has a refractive power of +20 diopters. (A)</p> Signup and view all the answers

    What causes the release of tension in the suspensory ligaments during accommodation?

    <p>Contraction of the ciliary muscles. (C)</p> Signup and view all the answers

    What is the initial change that occurs to rhodopsin when exposed to light?

    <p>It activates and decomposes into protein and all-trans-retinal. (C)</p> Signup and view all the answers

    How long does it take for the cones to fully adapt to darkness?

    <p>10 minutes (B)</p> Signup and view all the answers

    Which vitamin is essential for the recycling of 11-cis-retinal in the photoreceptor cells?

    <p>Vitamin A (B)</p> Signup and view all the answers

    What is the consequence of vitamin A deficiency in relation to vision?

    <p>Night blindness and degeneration of retinal layers (A)</p> Signup and view all the answers

    What mechanism occurs when the retina adapts to light?

    <p>Decrease in vitamin A concentration (A), Pupil size decreases (C)</p> Signup and view all the answers

    How are rods affected compared to cones in dark adaptation?

    <p>Rods adapt for a longer time than cones. (D)</p> Signup and view all the answers

    Which type of ganglion cells constitutes the majority in the retina?

    <p>W ganglion cells (D)</p> Signup and view all the answers

    What is the primary substance produced by converting all-trans-retinol in the photoreceptors?

    <p>11-cis-retinal (B)</p> Signup and view all the answers

    Flashcards

    Refraction

    The bending of light as it passes from one medium to another with a different density.

    Refractive Index (RI)

    The ratio of the speed of light in a vacuum to the speed of light in a medium. It indicates how much the speed of light decreases in that medium.

    Convex Lens

    A lens that converges light rays to a point, making them meet.

    Concave Lens

    A lens that diverges light rays, making them spread out.

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    Accommodation

    The ability of the eye to change its refractive power to focus on objects at different distances, achieved by adjusting the shape of the lens.

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    Myopia

    Nearsightedness. The image of distant objects falls in front of the retina.

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    Hyperopia

    Farsightedness. The image of near objects falls behind the retina.

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    Astigmatism

    An uneven curvature of the cornea, causing the image to be focused differently in different planes.

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    What is accommodation?

    The process by which the eye changes its refractive power to focus on objects at different distances. It involves adjusting the shape of the lens.

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    How does the eye accommodate for near objects?

    The ciliary muscles contract, which relaxes the suspensory ligaments, making the lens more convex and increasing its refractive power.

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    How does the eye accommodate for far objects?

    The ciliary muscles relax, tightening the suspensory ligaments, flattening the lens and reducing its refractive power.

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    What is presbyopia?

    A condition where the eye's ability to accommodate decreases with age, making it difficult to focus on near objects. This happens due to decreased lens elasticity, lens hardening, and protein degeneration.

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    What is the iris?

    The colored part of the eye that controls the amount of light entering the eye by adjusting the size of the pupil.

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    What is the pupil?

    The opening in the center of the iris that allows light to pass through the lens to the retina.

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    What is the sphincter pupillae?

    The circular muscle of the iris innervated by the parasympathetic nervous system (PSNS). It contracts to constrict the pupil.

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    What is the dilator pupillae?

    The radial muscle of the iris innervated by the sympathetic nervous system (SNS). It contracts to dilate the pupil.

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    Aqueous Humor

    The fluid that fills the anterior and posterior chambers of the eye. It is produced by the ciliary processes and circulates through the chambers, ultimately draining into the Schlemm's canal.

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    Intraocular Pressure (IOP)

    The pressure exerted by the aqueous humor within the eye. It is normally maintained at about 15 mmHg. Increased IOP can lead to glaucoma.

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    Glaucoma

    A condition characterized by increased pressure within the eye. This pressure can damage the optic nerve, leading to vision loss. It's a major cause of blindness.

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    Retina

    The neural layer of the eye that contains light-sensitive cells called photoreceptors. It is responsible for converting light signals into electrical impulses that are sent to the brain.

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    Optic Disc

    The point in the retina where the optic nerve and blood vessels enter and leave the eye. It's where the axons of ganglion cells converge.

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    Fovea

    A small area in the center of the retina. It contains a high density of cones and few rods, making it responsible for sharp central vision.

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    Photoreceptors

    The light-sensitive cells in the retina, divided into rods and cones. Rods detect low-light conditions and cones detect color.

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    Neural Connection in Retina

    The basic pathway of information processing in the retina: Light signals are captured by photoreceptors, then processed by bipolar cells and finally transmitted to the brain by ganglion cells.

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    Amacrine cells

    Specialized retinal cells that inhibit bipolar cells, enhancing contrast borders and sharpening edges in visual perception.

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    Phototransduction

    The process by which light energy is converted into neural signals in the retina.

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    Rhodopsin

    A light-sensitive pigment in rods that initiates the phototransduction cascade in low light conditions.

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    Scotopsin

    A protein component of rhodopsin, responsible for capturing light energy.

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    Color pigments

    Light-sensitive pigments in cones responsible for color vision.

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    Rhodopsin activation

    The breakdown of rhodopsin to metarhodopsin II, triggered by light energy, initiating the phototransduction cascade.

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    Photopsin

    The protein component of color pigments, responsible for capturing specific wavelengths of light for color vision.

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    cGMP reduction

    The decrease in cyclic GMP (cGMP) levels, leading to closure of sodium channels and hyperpolarization of photoreceptor cells.

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    Hyperpolarization

    A decrease in the membrane potential of a neuron, making it less likely to fire an action potential.

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    Vitamin A

    Vitamin A is a lipid-soluble vitamin that cannot be produced by the body. It is essential for vision and plays a critical role in the function of photoreceptor cells.

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    Adaptation (of the eye)

    The process by which the retina adjusts its sensitivity to light levels, allowing us to see in both bright and dim environments.

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    Retinol cycle

    The conversion of all-trans-retinol back into 11-cis-retinal is essential for the regeneration of rhodopsin and color pigments.

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    Vitamin A deficiency

    A deficiency in Vitamin A can lead to night blindness, a condition where it is difficult to see in low light conditions. It can also lead to degeneration of the neuronal layers of the retina.

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    W ganglion cells

    A type of ganglion cell in the retina responsible for processing information related to color and fine detail.

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    Y ganglion cells

    A type of ganglion cell in the retina that processes information related to motion and dim lighting.

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    Study Notes

    Physiology of Vision

    • Light: Electromagnetic radiation, wavelengths range from 400-700nm (visible light), ultraviolet (<400nm) and infrared (>700nm)
    • Light travels at 300,000km/sec in a vacuum. Speed changes when passing through different mediums.
    • Refractive Index (RI): RI = speed of light in air / speed of light in medium.
      • Cornea RI = 1.38
      • Aqueous humor RI = 1.33
      • Vitreous humor RI = 1.34
      • Lens RI = 1.4
    • Most refraction in the eye occurs at the cornea-air interface.
    • Convex lenses converge light rays, focusing at a single point.
    • Concave lenses diverge light rays.
    • Power of a lens is measured in diopters (1/focal length in meters). Convex lenses have positive diopters, concave lenses have negative.
    • A single-lens eye has a refractive power of +59D.

    Refractive Errors of the Eye

    • Myopia (Nearsightedness): Image of distant objects focuses in front of the retina, caused by a long eyeball or a strong lens. Corrected with concave lenses.
    • Hyperopia (Farsightedness): Image of near objects focuses behind the retina, caused by a short eyeball or a weak lens. Corrected with convex lenses.
    • Astigmatism: Uneven curvature of the cornea causes the image to be focused at different distances in different planes. Corrected using cylindrical lenses.
    • Keratoconus: Bulging of the cornea causes the image not to focus correctly on the retina, corrected with contact lenses.

    Accommodation

    • Process by which the eye changes its refractive power to focus on objects at different distances.
    • Ciliary muscles contract, relaxing suspensory ligaments, allowing lens to thicken (more convex) and increasing refractive power.
    • Maximum refractive power is +34D in young individuals and +20D in relaxed state.
    • Accommodation process is a reflex action: The process is triggered by blurred images on the retina. Stimulation of PSNS fibers contraction of ciliary muscles & change in the lens shape. Edinger-Westphal nucleus plays a critical role in triggering this response.
    • The stimulus is a blurred image of near objects on the retina. Sensory information travels through the optic nerve (CN II) and motor response is sent through the oculomotor nerve (CN III) by activating the Edinger-Westphal nucleus to stimulate ciliary muscles.

    Presbyopia

    • Reduction in the ability to accommodate (focus on near objects) with aging due to decreased lens elasticity.

    Pupil

    • Opening in the iris that controls the amount of light entering the eye.
    • Size ranges from 1.5mm (constricted) to 8mm (dilated).
    • Pupil diameter is proportional to light intensity. Large pupils allow more light; small pupils reduce light.
    • Pupil constriction (miosis): Occurs in bright light, stimulated by parasympathetic (PSNS) fibers.
    • Pupil dilation (mydriasis): Occurs in dim light, stimulated by sympathetic (SNS) fibers.

    Aqueous Humor

    • Fluid in the anterior and posterior chambers of the eye.
    • Produced by ciliary processes.
    • Maintains intraocular pressure (IOP).
    • Drains into Schlemm's canal, then general circulation.

    Retina

    • Neural tissue lining the back of the eye.
    • Contains photoreceptors (rods and cones) for light detection, and other neurons for processing signals.
    • Inner two thirds of the retina is supplied by the central retinal artery; outer one third by choroid layer (diffusion).
    • Fovea: Area of highest visual acuity, Contains only cones.

    Phototransduction

    • Process of converting light energy into neural signals in the retina.

    • Stage 1: Light activates rhodopsin (11-cis-retinal and protein).

    • Stage 2: Activated rhodopsin activates phosphodiesterase, decreasing cGMP levels.

    • Stage 3: Sodium channels close, resulting in hyperpolarization leading to inhibition of neurotransmitter release.

    • Dark: Sodium permeable; constantly depolarized, high release of inhibitory neurotransmitters.

    • Light: Low permeability to sodium; hyperpolarized; low/absent release of neurotransmitters.

    Vitamin A

    • Essential: Part of rhodopsin; converted into 11-cis-retinal, which is recycled, enabling rod function and preventing vitamin A deficiency (night blindness and retinal degeneration).
    • Lipid-soluble: cannot be produced in the body and must be obtained through the diet or supplements; Stored in the liver.

    Visual Pathway

    • Visual fields: Temporal and nasal visual fields.
    • Optic nerve: Carries visual signals from retina to the brain.
    • Optic chiasm: Point where nasal fibers decussate; temporal fibers do not.
    • Optic tract: carries signals to the lateral geniculate body (LGN).
    • Optic radiation: Carries signals from the LGN to the visual cortex.
    • Visual cortex: Processes visual information, located in the occipital lobe.

    Visual Field Defects

    • Bitemporal hemianopia: Damage to the optic chiasm.
    • Homonymous hemianopia: Damage to the optic tract or optic radiation.

    Visual Pathway (Optic Nerve, LGB, Optic Tract, Optic Radiation)

    • Primary visual pathway: nerve transmits signals from retina to Lateral Geniculate Body (LGN) through the optic chiasm; then to optic radiations to the Visual Cortex.
    • LGN: relays information from retina to the visual cortex of the brain, contains 6 layers of cells, magnocellular (1, 2); parvocellular (3-6) layers.
    • The primary visual cortex (PVC) located on the calcarine fissure of the occipital lobe receives signals from both eyes.
    • Colored visual information and acute visual information are processed by parvocellular and magnocellular layers of the LGB

    Visual Streams

    • Dorsal stream ("Where" stream): Processes information about motion, depth, and spatial location.
    • Ventral stream ("What" stream): Processes information about object recognition, color, etc.

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