Opioids Effect on Pain Modulation Pathway
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Questions and Answers

How do opioids contribute to analgesia in the cortex?

  • By enhancing synaptic transmission
  • By producing euphoric effects (correct)
  • By making pain more troublesome
  • By producing excitatory effects

    • What effect do opioids have on GABAergic neurons within the PAG?

  • Destroy them
  • Stimulate them
  • Inhibit them (correct)
  • Have no effect on them

    • How do opioids affect descending modulation?

  • They increase descending inhibition (correct)
  • They have no effect on descending modulation
  • They stimulate descending excitation
  • They decrease descending inhibition

    • What is the direct effect of opioids at the synapse in the dorsal horn of the spinal cord?

    <p>Inhibit transmission</p> Signup and view all the answers

    According to very recent work mentioned, what is a direct effect of opioids on nociceptive neurons?

    <p>Inhibition</p> Signup and view all the answers

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