Opioids Effect on Pain Modulation Pathway

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DaringPulsar
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How do opioids contribute to analgesia in the cortex?

By producing euphoric effects

What effect do opioids have on GABAergic neurons within the PAG?

Inhibit them

How do opioids affect descending modulation?

They increase descending inhibition

What is the direct effect of opioids at the synapse in the dorsal horn of the spinal cord?

Inhibit transmission

According to very recent work mentioned, what is a direct effect of opioids on nociceptive neurons?

Inhibition

Explore how opioids impact pain modulation by affecting the cortex, PAG, RVM, and the synapse in the dorsal horn. Learn about the euphoric effects of opioids and their role in analgesia.

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