Podcast
Questions and Answers
What phenomenon contributes to the increased risk of overdose during the first two weeks following release from residential treatment?
What phenomenon contributes to the increased risk of overdose during the first two weeks following release from residential treatment?
- Increased psychological cravings for the drug
- Improved metabolic clearance of the drug
- Enhanced drug potency due to new formulations
- Loss of tolerance to the drug after a period of abstinence (correct)
Which central nervous system depressant is most commonly associated with increased risk when combined with heroin?
Which central nervous system depressant is most commonly associated with increased risk when combined with heroin?
- Caffeine
- Alcohol and benzodiazepines (correct)
- Antidepressants
- Stimulants like amphetamines
Tolerance to heroin can diminish when the drug is used in what context?
Tolerance to heroin can diminish when the drug is used in what context?
- In a new environment different from usual use settings (correct)
- In a familiar environment where use typically occurs
- When combined with stimulants to counteract effects
- After switching to a different route of administration
What is one primary mechanism by which tolerance develops in individuals using heroin?
What is one primary mechanism by which tolerance develops in individuals using heroin?
Which feature does NOT typically develop tolerance in heroin users?
Which feature does NOT typically develop tolerance in heroin users?
What is the impact of injectable drug use on health risks compared to oral or inhalation methods?
What is the impact of injectable drug use on health risks compared to oral or inhalation methods?
Which of the following factors does NOT contribute to an increased risk of overdose?
Which of the following factors does NOT contribute to an increased risk of overdose?
Which statement accurately reflects the effects of tolerance in opioid users?
Which statement accurately reflects the effects of tolerance in opioid users?
What is the primary pharmacological mechanism thought to be involved in developing tolerance to opioids?
What is the primary pharmacological mechanism thought to be involved in developing tolerance to opioids?
How does the lifestyle of heroin addicts indirectly affect their health?
How does the lifestyle of heroin addicts indirectly affect their health?
Which demographic is most commonly represented among individuals visiting emergency departments for drug overdose?
Which demographic is most commonly represented among individuals visiting emergency departments for drug overdose?
What is a notable gender difference observed in unintentional drug poisoning cases?
What is a notable gender difference observed in unintentional drug poisoning cases?
Which type of opioids is associated with the highest number of drug-poisoning deaths?
Which type of opioids is associated with the highest number of drug-poisoning deaths?
What method of heroin administration has been reported the least by 8th, 10th, and 12th graders?
What method of heroin administration has been reported the least by 8th, 10th, and 12th graders?
Which of the following opioids is most commonly reported to be illicitly used among high school students?
Which of the following opioids is most commonly reported to be illicitly used among high school students?
What was the percentage of non-college-attending young adults who reported illicitly using prescription opioids?
What was the percentage of non-college-attending young adults who reported illicitly using prescription opioids?
What factor mentioned contributes to the recent rise in heroin use in the United States?
What factor mentioned contributes to the recent rise in heroin use in the United States?
Which age group showed the highest lifetime heroin use according to the data provided?
Which age group showed the highest lifetime heroin use according to the data provided?
What percentage of grade-12 students indicated that prescription opioids would be 'fairly easy' or 'very easy' to obtain?
What percentage of grade-12 students indicated that prescription opioids would be 'fairly easy' or 'very easy' to obtain?
Which of the following drugs is likely to result in the fastest onset of tolerance among opioid users?
Which of the following drugs is likely to result in the fastest onset of tolerance among opioid users?
What is the primary way that most high school students obtain prescription opioids illicitly?
What is the primary way that most high school students obtain prescription opioids illicitly?
Which of the following is NOT a pharmacological effect of opioid use?
Which of the following is NOT a pharmacological effect of opioid use?
In the context of opioid withdrawal, which of the following symptoms is commonly observed?
In the context of opioid withdrawal, which of the following symptoms is commonly observed?
What is the trend in the use of Vicodin among young people from 2005 to 2014?
What is the trend in the use of Vicodin among young people from 2005 to 2014?
What age group reported the highest rates of prescription pain reliever abuse disorder in 2014?
What age group reported the highest rates of prescription pain reliever abuse disorder in 2014?
Which factor has contributed to the high number of chronic pain sufferers developing opioid addiction?
Which factor has contributed to the high number of chronic pain sufferers developing opioid addiction?
What percentage of opioids prescribed in 1999 were stronger than morphine?
What percentage of opioids prescribed in 1999 were stronger than morphine?
Which demographic reported the second-most illicit use of drug classes after cannabis?
Which demographic reported the second-most illicit use of drug classes after cannabis?
What was the percentage of illicit non-heroin opioid use reported by 23-26 year olds in 2014?
What was the percentage of illicit non-heroin opioid use reported by 23-26 year olds in 2014?
What shift occurred in opioid prescriptions from 1999 to 2012?
What shift occurred in opioid prescriptions from 1999 to 2012?
Approximately how many young adults (ages 18-25) were estimated to be nonmedical users of prescription pain relievers in 2014?
Approximately how many young adults (ages 18-25) were estimated to be nonmedical users of prescription pain relievers in 2014?
What did research from the 1950s and 1960s suggest about the behavior of older heroin users?
What did research from the 1950s and 1960s suggest about the behavior of older heroin users?
What trend has been observed regarding the prevalence of illicit non-heroin opioid use among young age categories since 2010?
What trend has been observed regarding the prevalence of illicit non-heroin opioid use among young age categories since 2010?
What is the primary effect of high doses of opioids on the respiratory system?
What is the primary effect of high doses of opioids on the respiratory system?
In which format was fentanyl indirectly used during the Moscow theater hostage crisis?
In which format was fentanyl indirectly used during the Moscow theater hostage crisis?
What is a common outcome reported among heroin users who attempt to stop on their own?
What is a common outcome reported among heroin users who attempt to stop on their own?
Which condition tends to show tolerance development when using opioids?
Which condition tends to show tolerance development when using opioids?
What factor does NOT typically influence the likelihood of maturing out of heroin addiction?
What factor does NOT typically influence the likelihood of maturing out of heroin addiction?
What is an observed effect of opioid use concerning the seizure threshold?
What is an observed effect of opioid use concerning the seizure threshold?
What trend was noted regarding heroin use among individuals over 50 between 1994 and 2004 in the US?
What trend was noted regarding heroin use among individuals over 50 between 1994 and 2004 in the US?
Which of the following substances is not typically associated with causing convulsions at high doses?
Which of the following substances is not typically associated with causing convulsions at high doses?
What is the estimated percentage range of addicts who may eventually mature out of heroin addiction?
What is the estimated percentage range of addicts who may eventually mature out of heroin addiction?
What may be a contributing factor to the increasing number of heroin addicts among seniors?
What may be a contributing factor to the increasing number of heroin addicts among seniors?
Flashcards
Opioid Mortality Rate
Opioid Mortality Rate
The rate at which people die from opioid-related causes.
Overdose Risk
Overdose Risk
The likelihood of experiencing a drug overdose, often due to factors like high drug use frequency or injecting drugs.
Drug Poisoning
Drug Poisoning
A situation where someone takes a drug and suffers a health crisis, requiring immediate medical attention.
Shooting Up
Shooting Up
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Opioid Addiction
Opioid Addiction
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Needle-Associated Diseases
Needle-Associated Diseases
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Polydrug Use
Polydrug Use
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Lifestyle Effects of Opioid Addiction
Lifestyle Effects of Opioid Addiction
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Illicit opioid use
Illicit opioid use
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Decreasing illicit opioid prevalence
Decreasing illicit opioid prevalence
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Pain relievers: Second most illicit drug
Pain relievers: Second most illicit drug
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Opioid abuse disorder: Highest rate in 18-25 year olds
Opioid abuse disorder: Highest rate in 18-25 year olds
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Figure 11-3: Opioid use by age group
Figure 11-3: Opioid use by age group
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Increased prescription of strong opioids
Increased prescription of strong opioids
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Opioid addiction risk in chronic pain
Opioid addiction risk in chronic pain
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Maturing out of heroin addiction
Maturing out of heroin addiction
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Aging and heroin use
Aging and heroin use
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Winick (1962) study
Winick (1962) study
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Loss of Tolerance in Heroin Users
Loss of Tolerance in Heroin Users
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Heroin Overdose: Mixing Drugs
Heroin Overdose: Mixing Drugs
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Heroin Overdose in Experienced Users
Heroin Overdose in Experienced Users
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Environmental Influence on Heroin Tolerance
Environmental Influence on Heroin Tolerance
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Prescription Opioid Overdose Deaths
Prescription Opioid Overdose Deaths
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Maturing Out
Maturing Out
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Spontaneous Remission of Opioid Addiction
Spontaneous Remission of Opioid Addiction
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Opioid Overdose
Opioid Overdose
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Fentanyl Overdose
Fentanyl Overdose
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Fentanyl Gas
Fentanyl Gas
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Lowered Seizure Threshold in Opioid Use
Lowered Seizure Threshold in Opioid Use
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Moscow Theater Hostage Crisis
Moscow Theater Hostage Crisis
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Chemical Subjugation
Chemical Subjugation
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Opioid Gas
Opioid Gas
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Hostage Situation
Hostage Situation
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Abuse-Deterrent OxyContin
Abuse-Deterrent OxyContin
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Opioid Prevalence
Opioid Prevalence
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Rising Heroin Use
Rising Heroin Use
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Monitoring the Future Survey
Monitoring the Future Survey
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Trend of Illicit Opioid Use
Trend of Illicit Opioid Use
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Non-Heroin Opioids
Non-Heroin Opioids
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Accessibility of Prescription Opioids
Accessibility of Prescription Opioids
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Sources of Illicit Opioids
Sources of Illicit Opioids
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Popular Illicit Opioids
Popular Illicit Opioids
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Study Notes
Opioid Use Prevalence
- Globally, approximately 0.7% of adults use opioids.
- North America shows a significantly higher prevalence at about 3.8%.
- Heroin use in the US has shown an upward trend recently, partially attributed to reformulated OxyContin and decreased heroin costs.
- 0.9-1% of 8th, 10th, and 12th graders have used heroin in their lifetime, compared to 0.2% using methods besides injection.
- College students showed lower heroin use (0.3%), while young adults (19-28) not attending college had a higher rate (1.4%).
- Prescription opioid use (Vicodin, OxyContin, Percocet) is notably higher among young people outside of medical supervision.
- 10% of 12th graders and college students used illicit prescription opioids.
- Over 16% of young adults (not in college) had illicitly used prescription opioids.
- Prescription opioids were largely obtained for free or from friends.
Opioid Use Trends
- Illicit non-heroin opioid use increased in the mid-1990s and then flattened.
- Use was highest among those under 30, peaking at 10% for 23-26 year olds in 2008 and 2010.
- Vicodin use in young adults significantly declined since 2005 (from 9.3% to 4.8% in 2014).
- Pain relievers are the second most used illicit drug class, after cannabis, with young people reporting the highest use.
- Data from the 2014 National Survey of Drug Use and Health shows this.
- More than 978,000 nonmedical users of prescription pain relievers were between 18 and 25 years old in 2014.
Opioid Overdose Deaths
- Overdose deaths involving prescription opioids have increased considerably since 1999.
- 70% of opioid overdose deaths involved natural and semi-synthetic opioids (morphine, hydrocodone, and oxycodone).
- Methadone alone is responsible for 26% of prescription opioid overdose deaths in 2014.
- In 2013, the US had a significantly higher rate of drug-related mortality than the global average (4.6 times higher).
Heroin Overdoses
- Heroin overdose deaths in the US increased significantly from 2010 to 2013.
- Overdose is the leading cause of death for heroin users.
- Overdose risk is increased by mixing heroin with other central nervous system depressants (like alcohol or benzodiazepines). Many celebrities have died from this.
- The risk of overdose is also increased when tolerance has greatly decreased due to a period of abstinence.
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