Questions and Answers
What are other names for buprenorphine?
What are other names for naltrexone?
What are other names for Narcan?
What are opioid agonists?
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What are opioid antagonists?
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What is methadone?
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How is methadone administered?
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How is buprenorphine administered?
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How is naltrexone administered?
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What are the requirements for methadone treatment?
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What is buprenorphine?
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Study Notes
Buprenorphine
- Trade names include Buprenex®, Suboxone®, and Subutex®.
- Acts as a partial opioid agonist, providing similar benefits to methadone but with fewer side effects.
- Can be adjusted after patients stabilize to minimize cravings and withdrawal.
Naltrexone
- Known by the trade names ReVia, Vivitrol, and Depade.
- Administered orally, typically 50 mg once daily, with higher doses possible (100-150 mg) for supervised use.
- Requires abstinence from opioids for at least 7 days prior to starting the medication.
Narcan (Naloxone)
- Recognized as opioid reversal agents, used to counteract the effects of opioids.
- Provides critical emergency intervention for opioid overdoses.
Opioid Agonists
- Agonists actively bind to opioid receptors in the brain, producing full opioid effects.
- Full agonist examples include heroin, oxycodone, methadone, hydrocodone, morphine, and opium.
Opioid Antagonists
- These bind to opioid receptors but do not activate them, blocking the effects of opioids.
- Naloxone is a key example, used primarily to reverse opioid overdoses.
Methadone
- A long-acting oral opioid used for detoxification and maintenance therapy in opioid use disorder (OUD).
- Properties similar to heroin but with reduced potency and slower onset.
- Administered daily, available as liquid, powder, or tablets, and requires supervision initially.
Methadone Administration
- Patients must typically receive methadone under practitioner supervision initially before home administration.
- Treatment duration often lasts a minimum of 12 months, with gradual dose reduction to prevent withdrawal.
Buprenorphine Administration
- Treatment requires patients to abstain from opioids for 12-24 hours and be in early withdrawal.
- Once stabilized, dosing frequency may shift to alternate days based on individual needs.
Naltrexone Administration
- May be taken with or without food, regular monitoring is recommended, particularly in the early stages.
- Must confirm absence of recent opioid use through urine tests prior to starting treatment.
Requirements for Methadone
- Patients undergo assessments for stability and compliance before receiving medications independently.
Overview of Buprenorphine
- Serves as an effective alternative to methadone for OUD, characterized by a lower side effect profile and minimal withdrawal upon discontinuation.
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Description
Explore the essential information about key opioid medications including Buprenorphine, Naltrexone, and Naloxone. This quiz will cover their uses, effects, and mechanisms, providing a comprehensive view of opioid agonists and antagonists. Test your knowledge on these critical substances used in opioid treatment and reversal.
