Podcast
Questions and Answers
What are other names for buprenorphine?
What are other names for buprenorphine?
What are other names for naltrexone?
What are other names for naltrexone?
What are other names for Narcan?
What are other names for Narcan?
What are opioid agonists?
What are opioid agonists?
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What are opioid antagonists?
What are opioid antagonists?
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What is methadone?
What is methadone?
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How is methadone administered?
How is methadone administered?
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How is buprenorphine administered?
How is buprenorphine administered?
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How is naltrexone administered?
How is naltrexone administered?
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What are the requirements for methadone treatment?
What are the requirements for methadone treatment?
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What is buprenorphine?
What is buprenorphine?
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Study Notes
Buprenorphine
- Trade names include Buprenex®, Suboxone®, and Subutex®.
- Acts as a partial opioid agonist, providing similar benefits to methadone but with fewer side effects.
- Can be adjusted after patients stabilize to minimize cravings and withdrawal.
Naltrexone
- Known by the trade names ReVia, Vivitrol, and Depade.
- Administered orally, typically 50 mg once daily, with higher doses possible (100-150 mg) for supervised use.
- Requires abstinence from opioids for at least 7 days prior to starting the medication.
Narcan (Naloxone)
- Recognized as opioid reversal agents, used to counteract the effects of opioids.
- Provides critical emergency intervention for opioid overdoses.
Opioid Agonists
- Agonists actively bind to opioid receptors in the brain, producing full opioid effects.
- Full agonist examples include heroin, oxycodone, methadone, hydrocodone, morphine, and opium.
Opioid Antagonists
- These bind to opioid receptors but do not activate them, blocking the effects of opioids.
- Naloxone is a key example, used primarily to reverse opioid overdoses.
Methadone
- A long-acting oral opioid used for detoxification and maintenance therapy in opioid use disorder (OUD).
- Properties similar to heroin but with reduced potency and slower onset.
- Administered daily, available as liquid, powder, or tablets, and requires supervision initially.
Methadone Administration
- Patients must typically receive methadone under practitioner supervision initially before home administration.
- Treatment duration often lasts a minimum of 12 months, with gradual dose reduction to prevent withdrawal.
Buprenorphine Administration
- Treatment requires patients to abstain from opioids for 12-24 hours and be in early withdrawal.
- Once stabilized, dosing frequency may shift to alternate days based on individual needs.
Naltrexone Administration
- May be taken with or without food, regular monitoring is recommended, particularly in the early stages.
- Must confirm absence of recent opioid use through urine tests prior to starting treatment.
Requirements for Methadone
- Patients undergo assessments for stability and compliance before receiving medications independently.
Overview of Buprenorphine
- Serves as an effective alternative to methadone for OUD, characterized by a lower side effect profile and minimal withdrawal upon discontinuation.
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Description
Explore the essential information about key opioid medications including Buprenorphine, Naltrexone, and Naloxone. This quiz will cover their uses, effects, and mechanisms, providing a comprehensive view of opioid agonists and antagonists. Test your knowledge on these critical substances used in opioid treatment and reversal.
