Ondansetron Side Effects

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Questions and Answers

What is a contraindication for the use of diphenoxylate with atropine?

CNS depressants (correct)

Hypertension

Diabetes

Asthma

What is a non-pharmacological measure to manage diarrhea?

Use antibiotics

Use antacids

Increase fluid intake

Take clear liquids (correct)

What is a potential side effect of long-term use of diphenoxylate with atropine?

Paralytic ileus (correct)

Nausea

Diarrhea

Vomiting

When should metoclopramide be given to help with GI emptying?

Before meals Signup and view all the answers

What is a potential cause of diarrhea?

All of the above Signup and view all the answers

What should be monitored in patients taking promethazine?

CNS depression Signup and view all the answers

What is a potential interaction with diphenoxylate with atropine?

CNS depressants Signup and view all the answers

What should be assessed in patients taking antiemetics?

Emesis, number, quantity, and appearance Signup and view all the answers

What is a teaching instruction for patients taking antiemetics?

Do not drive Signup and view all the answers

What is a potential risk of using antiemetics?

EPS Signup and view all the answers

What is a potential side effect of ondansetron?

Headache, dizziness, and fatigue Signup and view all the answers

What is the mechanism of action of bisacodyl?

Increases peristalsis by direct effect on intestinal smooth muscle Signup and view all the answers

What is a contraindication for the use of bisacodyl?

Appendicitis Signup and view all the answers

What is the primary action of ondansetron in the treatment of nausea and vomiting?

Blocks serotonin receptors in the CTZ Signup and view all the answers

What is the primary goal of administering bisacodyl to a patient?

To stimulate the GI tract and produce a bowel movement Signup and view all the answers

What is a common nonpharmacologic measure to manage vomiting?

Consumption of weak tea Signup and view all the answers

What is a potential side effect of promethazine?

Urinary retention Signup and view all the answers

What is a potential complication of untreated constipation?

Bowel obstruction Signup and view all the answers

Why is it important to assess a patient's abdomen before administering bisacodyl?

To check for signs of appendicitis Signup and view all the answers

What is the classification of bisacodyl as a laxative?

Stimulant laxative Signup and view all the answers

What is the primary use of metoclopramide in the management of gastrointestinal disorders?

Treatment of postoperative emesis Signup and view all the answers

What is a potential risk factor for bowel obstruction?

Chronic laxative use Signup and view all the answers

What is the primary action of ondansetron?

Inhibits the release of serotonin Signup and view all the answers

What is a contraindication for the use of promethazine?

Glaucoma Signup and view all the answers

What is a non-pharmacological treatment for constipation?

Diet with high fiber Signup and view all the answers

What is a potential interaction of promethazine with other medications?

False pregnancy test Signup and view all the answers

What is the most common side effect of bisacodyl?

Abdominal cramping and diarrhea Signup and view all the answers

What is a potential interaction with bisacodyl?

Antacids Signup and view all the answers

What is the primary action of metoclopramide in the treatment of gastrointestinal disorders?

Blocking dopamine receptors in the CTZ Signup and view all the answers

What is the primary indication for the use of bisacodyl?

Relief of constipation Signup and view all the answers

What is a common side effect of ondansetron?

All of the above Signup and view all the answers

What is the action of bisacodyl as a laxative?

Increases peristalsis by direct effect on the smooth muscle of the intestine Signup and view all the answers

What is a potential interaction between bisacodyl and another medication?

Reduces the absorption of oral antibiotics Signup and view all the answers

What is a side effect of bisacodyl?

Abdominal cramps Signup and view all the answers

What is a nonpharmacologic measure to manage diarrhea?

Consumption of Pedialyte Signup and view all the answers

What is a contraindication for bisacodyl?

Pregnancy Signup and view all the answers

What is a characteristic of antiemetics?

They block histamine 1 and dopamine receptors Signup and view all the answers

What is the purpose of ondansetron in cancer chemotherapy?

To control nausea and vomiting Signup and view all the answers

What is a nursing intervention for patients taking laxatives?

Monitor I & O, increase fluids and fiber Signup and view all the answers

What is a result of bisacodyl's action?

Bowel movements occur within 6-8 hours Signup and view all the answers

Study Notes

Medication for Gastrointestinal Disorders

Antiemetics:
- Indications: vomiting, diarrhea, motion sickness, and chemotherapy-induced nausea and vomiting
- Contraindications: glaucoma, CNS depression, GI obstruction, hemorrhage, or perforation
- Side effects: drowsiness, dry mouth and eyes, photosensitivity, urinary retention/constipation, EPS
- Examples: promethazine, ondansetron, metoclopramide
Antidiarrheals:
- Indications: diarrhea, fecal impaction, laxative abuse, malabsorption disorders, inflammatory bowel disease, and stress
- Contraindications: similar to opioids and anticholinergics
- Side effects: long-term use – paralytic ileus
- Examples: diphenoxylate with atropine
Laxatives:
- Indications: constipation, bowel prep, short-term treatment for constipation
- Types: osmotic (saline), stimulant (bisacodyl), bulk-forming (Metamucil), and emollient (stool softeners – docusate sodium)
- Contraindications: undiagnosed abdominal pain, inflammatory disorders of the GI tract, bowel obstruction, fecal impaction, pregnancy

Nursing Process

Assessment:
- Medical/medication history
- Baseline vital signs
- Bowel sounds, diarrhea
- Narcotic use history
Interventions/Teaching:
- Monitor VS, fluid/electrolyte status
- Notify HCP if diarrhea continues longer than 48 hours or acute abdominal pain occurs
- Do not take with CNS depressants
- Take medication as prescribed
- Drink a lot of fluids
- No fried foods or milk products
- Constipation can result from overuse

Practice Questions

Ondansetron:
- Side effects: headache, dizziness, and fatigue
Bisacodyl (Dulcolax):
- Action: increases peristalsis by direct effect on intestinal smooth muscle
- Contraindications: appendicitis, inflammatory disorders of the GI tract, bowel obstruction, fecal impaction, pregnancy

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Description

This quiz assesses the nurse's knowledge of ondansetron side effects, including headache, dizziness, and fatigue. It's essential for nurses to recognize these symptoms to provide quality patient care.