16 Questions
Match the following enzymes with which reaction they catalyze in gluconeogenesis:
Reaction 1 = Pyruvate carboxylase Reaction 7 = Aldolase Reaction 5 = Glyceraldehyde-3-phosphate dehydrogenase Reaction 9 = Phosphoglucose isomerase
Match the following enzymes with which reaction they catalyze in gluconeogenesis:
Reaction 2 = Enolase Reaction 6 = Triose phosphate isomerase Reaction 10 = Glucose-6-phosphatase Reaction 3 = Phosphoglycerate mutase
Match the enzyme with the reaction it corresponds with in gluconeogenesis:
Reaction 4 = Phosphoglycerate isomerase Reaction 8 = Fructose 1,6 bisphosphatase Reaction 5 = Glyceraldehyde-3-phosphate dehydrogenase Reaction 10 - bypass = Glucose-6-phosphotase
Match the reactants with the reaction of gluconeogenesis:
Reaction 1 = Pyruvate -> Oxaloacetate Reaction 5 = 1-3 diphosphoglycerate <-> Glyceraldehyde Reaction 4 = 3-phosphoglycerate <-> 1-3 diphosphoglycerate Reaction 9 = 1,6 bisphosphate -> F6P
Match the reactants to the reaction of gluconeogenesis:
Reaction 3 = 2-phosphoglycerate <-> 3-phosphoglycerate Reaction 8 = Fructose 1,6 bisphosphate -> Fructose-6-phosphate Reaction 2 = Oxaloacetate -> Phosphoenolpyruvate Reaction 6 = Triose phosphate isomerase
Match the reaction with the reactant it corresponds to:
Reaction 10 = G-6-P -> glucose Reaction 7 = Dihydorxyacetone-phosphate + Glyceraldehyde -> Fructose 1,6 bisphosphate Reaction 8 = Fructose 1,6 bisphosphate -> F-6-P Reaction 9 = F-6-P <-> G-6-P
What 3 molecules can be converted into glucose?
lactate, glycerol, glycogenic amino acids
Insulin and glucagon are regulators of gluconeogenesis.
True
Lactate + NAD+ <-> NADH + H + pyruvate
What does this reaction show?
Cori cycle
How can glycerol enter the process of gluconeogenesis?
Being converted to dihydroxyacetone (DHAP)
Which 2 amino acids are not glycogenic and therefore, are ketogenic?
Leucine and lysine
Once in the cytosol, in the malate shuttle system, what is oxaloacetate converted to so it can exit the mitochondria?
Phosphoenolpyruvate
In the malate shuttle system, what is oxaloacetate converted to so it can exit the mitochondria?
Malate
In the lactate shuttle system, what is lactate converted to in the cytosol so it can enter the mitochondria?
Pyruvate
In the lactate shuttle system, once in the mitochondria, oxaloacetate is converted to __________________ to be used in gluconeogenesis.
Phosphoenolpyruvate
In the Cori cycle, where is lactate converted to pyruvate?
Liver
Test your knowledge of gluconeogenesis by matching enzymes with their corresponding reactions in the process. This quiz will help you reinforce your understanding of key enzymes involved in the production of glucose from non-carbohydrate sources.
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