Gluconeogenesis
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Questions and Answers

Match the following enzymes with which reaction they catalyze in gluconeogenesis:

Reaction 1 = Pyruvate carboxylase Reaction 7 = Aldolase Reaction 5 = Glyceraldehyde-3-phosphate dehydrogenase Reaction 9 = Phosphoglucose isomerase

Match the following enzymes with which reaction they catalyze in gluconeogenesis:

Reaction 2 = Enolase Reaction 6 = Triose phosphate isomerase Reaction 10 = Glucose-6-phosphatase Reaction 3 = Phosphoglycerate mutase

Match the enzyme with the reaction it corresponds with in gluconeogenesis:

Reaction 4 = Phosphoglycerate isomerase Reaction 8 = Fructose 1,6 bisphosphatase Reaction 5 = Glyceraldehyde-3-phosphate dehydrogenase Reaction 10 - bypass = Glucose-6-phosphotase

Match the reactants with the reaction of gluconeogenesis:

<p>Reaction 1 = Pyruvate -&gt; Oxaloacetate Reaction 5 = 1-3 diphosphoglycerate &lt;-&gt; Glyceraldehyde Reaction 4 = 3-phosphoglycerate &lt;-&gt; 1-3 diphosphoglycerate Reaction 9 = 1,6 bisphosphate -&gt; F6P</p> Signup and view all the answers

Match the reactants to the reaction of gluconeogenesis:

<p>Reaction 3 = 2-phosphoglycerate &lt;-&gt; 3-phosphoglycerate Reaction 8 = Fructose 1,6 bisphosphate -&gt; Fructose-6-phosphate Reaction 2 = Oxaloacetate -&gt; Phosphoenolpyruvate Reaction 6 = Triose phosphate isomerase</p> Signup and view all the answers

Match the reaction with the reactant it corresponds to:

<p>Reaction 10 = G-6-P -&gt; glucose Reaction 7 = Dihydorxyacetone-phosphate + Glyceraldehyde -&gt; Fructose 1,6 bisphosphate Reaction 8 = Fructose 1,6 bisphosphate -&gt; F-6-P Reaction 9 = F-6-P &lt;-&gt; G-6-P</p> Signup and view all the answers

What 3 molecules can be converted into glucose?

<p>lactate, glycerol, glycogenic amino acids</p> Signup and view all the answers

Insulin and glucagon are regulators of gluconeogenesis.

<p>True</p> Signup and view all the answers

Lactate + NAD+ <-> NADH + H + pyruvate

What does this reaction show?

<p>Cori cycle</p> Signup and view all the answers

How can glycerol enter the process of gluconeogenesis?

<p>Being converted to dihydroxyacetone (DHAP)</p> Signup and view all the answers

Which 2 amino acids are not glycogenic and therefore, are ketogenic?

<p>Leucine and lysine</p> Signup and view all the answers

Once in the cytosol, in the malate shuttle system, what is oxaloacetate converted to so it can exit the mitochondria?

<p>Phosphoenolpyruvate</p> Signup and view all the answers

In the malate shuttle system, what is oxaloacetate converted to so it can exit the mitochondria?

<p>Malate</p> Signup and view all the answers

In the lactate shuttle system, what is lactate converted to in the cytosol so it can enter the mitochondria?

<p>Pyruvate</p> Signup and view all the answers

In the lactate shuttle system, once in the mitochondria, oxaloacetate is converted to __________________ to be used in gluconeogenesis.

<p>Phosphoenolpyruvate</p> Signup and view all the answers

In the Cori cycle, where is lactate converted to pyruvate?

<p>Liver</p> Signup and view all the answers

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