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Questions and Answers
What is the location of pyruvate carboxylase responsible for pyruvate carboxylation?
What is the location of pyruvate carboxylase responsible for pyruvate carboxylation?
- In the mitochondrial matrix (correct)
- In the nucleus
- In the endoplasmic reticulum
- In the cytoplasm
What is the source of energy required for pyruvate carboxylation?
What is the source of energy required for pyruvate carboxylation?
- Hydrolysis of ATP (correct)
- Hydrolysis of GTP
- Hydrolysis of ADP
- Hydrolysis of AMP
What is the product of C2 phosphorylation by GTP during pyruvate carboxylation?
What is the product of C2 phosphorylation by GTP during pyruvate carboxylation?
- Acetyl-CoA
- Pyruvate
- Phosphoenolpyruvate (correct)
- Oxaloacetate
What is the name of the enzyme responsible for oxaloacetate decarboxylation during pyruvate carboxylation?
What is the name of the enzyme responsible for oxaloacetate decarboxylation during pyruvate carboxylation?
What is the name of the molecule that is produced by pyruvate carboxylation?
What is the name of the molecule that is produced by pyruvate carboxylation?
What is the name of the molecule that is required for C2 phosphorylation during pyruvate carboxylation?
What is the name of the molecule that is required for C2 phosphorylation during pyruvate carboxylation?
What is the name of the enzyme responsible for catalyzing the reaction of C2 phosphorylation during pyruvate carboxylation?
What is the name of the enzyme responsible for catalyzing the reaction of C2 phosphorylation during pyruvate carboxylation?
What is the name of the molecule that is produced by oxaloacetate decarboxylation during pyruvate carboxylation?
What is the name of the molecule that is produced by oxaloacetate decarboxylation during pyruvate carboxylation?
What is the name of the molecule that is produced by C2 phosphorylation during pyruvate carboxylation?
What is the name of the molecule that is produced by C2 phosphorylation during pyruvate carboxylation?
What is the name of the molecule that is required for pyruvate carboxylation?
What is the name of the molecule that is required for pyruvate carboxylation?
What is the location of pyruvate carboxylase responsible for pyruvate carboxylation?
What is the location of pyruvate carboxylase responsible for pyruvate carboxylation?
What is the source of energy required for pyruvate carboxylation?
What is the source of energy required for pyruvate carboxylation?
What is the product of C2 phosphorylation by GTP during pyruvate carboxylation?
What is the product of C2 phosphorylation by GTP during pyruvate carboxylation?
What is the name of the enzyme responsible for oxaloacetate decarboxylation during pyruvate carboxylation?
What is the name of the enzyme responsible for oxaloacetate decarboxylation during pyruvate carboxylation?
What is the name of the molecule that is produced by pyruvate carboxylation?
What is the name of the molecule that is produced by pyruvate carboxylation?
What is the name of the molecule that is required for C2 phosphorylation during pyruvate carboxylation?
What is the name of the molecule that is required for C2 phosphorylation during pyruvate carboxylation?
What is the name of the enzyme responsible for catalyzing the reaction of C2 phosphorylation during pyruvate carboxylation?
What is the name of the enzyme responsible for catalyzing the reaction of C2 phosphorylation during pyruvate carboxylation?
What is the name of the molecule that is produced by oxaloacetate decarboxylation during pyruvate carboxylation?
What is the name of the molecule that is produced by oxaloacetate decarboxylation during pyruvate carboxylation?
What is the name of the molecule that is produced by C2 phosphorylation during pyruvate carboxylation?
What is the name of the molecule that is produced by C2 phosphorylation during pyruvate carboxylation?
What is the name of the molecule that is required for pyruvate carboxylation?
What is the name of the molecule that is required for pyruvate carboxylation?
What is the name of the enzyme responsible for pyruvate carboxylation, and where is it present?
What is the name of the enzyme responsible for pyruvate carboxylation, and where is it present?
What is the source of energy required for pyruvate carboxylation?
What is the source of energy required for pyruvate carboxylation?
What is the product of C2 phosphorylation by GTP during pyruvate carboxylation?
What is the product of C2 phosphorylation by GTP during pyruvate carboxylation?
What is the name of the enzyme responsible for catalyzing the reaction that converts oxaloacetate to phosphoenolpyruvate?
What is the name of the enzyme responsible for catalyzing the reaction that converts oxaloacetate to phosphoenolpyruvate?
What molecule is released during the decarboxylation of oxaloacetate?
What molecule is released during the decarboxylation of oxaloacetate?
What is the role of PEPCK in pyruvate carboxylation?
What is the role of PEPCK in pyruvate carboxylation?
Where does the hydrolysis of ATP occur during pyruvate carboxylation?
Where does the hydrolysis of ATP occur during pyruvate carboxylation?
What is the product of pyruvate carboxylation?
What is the product of pyruvate carboxylation?
What is the source of energy for C2 phosphorylation during pyruvate carboxylation?
What is the source of energy for C2 phosphorylation during pyruvate carboxylation?
What is the location of pyruvate carboxylase, the enzyme responsible for pyruvate carboxylation?
What is the location of pyruvate carboxylase, the enzyme responsible for pyruvate carboxylation?
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Study Notes
Pyruvate Carboxylation
- Pyruvate carboxylase, the enzyme responsible for pyruvate carboxylation, is located in the mitochondria.
- The source of energy required for pyruvate carboxylation is ATP, which is hydrolyzed to ADP and Pi during the process.
Phosphorylation and Decarboxylation
- During pyruvate carboxylation, GTP is required for C2 phosphorylation, producing GDP and Pi as byproducts.
- The product of C2 phosphorylation is phosphoenolpyruvate (PEP).
- The enzyme responsible for oxaloacetate decarboxylation is phosphoenolpyruvate carboxykinase (PEPCK).
- CO2 is released during the decarboxylation of oxaloacetate.
Key Molecules Involved
- Pyruvate is the molecule that undergoes carboxylation to produce oxaloacetate.
- GTP is the molecule required for C2 phosphorylation during pyruvate carboxylation.
- Phosphoenolpyruvate (PEP) is the product of pyruvate carboxylation.
Enzymes and Their Roles
- Pyruvate carboxylase catalyzes the reaction of pyruvate carboxylation.
- Phosphoenolpyruvate carboxykinase (PEPCK) is the enzyme responsible for oxaloacetate decarboxylation.
- PEPCK also catalyzes the reaction that converts oxaloacetate to phosphoenolpyruvate (PEP).
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