5. Obstetrics and Gynecology Flashcards

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson
Download our mobile app to listen on the go
Get App

Questions and Answers

A hydatidiform mole is also known by what name?

  • Molar pregnancy (correct)
  • Placental carcinoma
  • Trophoblastic neoplasia
  • Choriocarcinoma variant

Gestational trophoblastic disease (GTD) is characterized by abnormal proliferation of what?

  • Amniotic fluid
  • Ovarian follicles
  • Endometrial lining
  • Trophoblastic (placental) tissue (correct)

Following aberrant fertilization, which condition is most likely to occur, representing a type of gestational trophoblastic disease?

  • Placenta previa
  • Abruptio placentae
  • Complete molar pregnancy (correct)
  • Ectopic pregnancy

Which of the following processes is central to the etiology of both complete and partial molar pregnancies?

<p>Aberrant fertilization (A)</p> Signup and view all the answers

A patient is diagnosed with gestational trophoblastic disease (GTD). Histopathological examination reveals widespread villous edema and trophoblastic proliferation with no identifiable embryonic or fetal tissue. Which specific type of GTD is most consistent with these findings?

<p>Complete hydatidiform mole (D)</p> Signup and view all the answers

A patient presents with abnormal uterine bleeding and significantly elevated hCG levels. Which condition is MOST likely?

<p>Complete hydatidiform mole (D)</p> Signup and view all the answers

Which of the following is the MOST common location for an ectopic pregnancy?

<p>Ampulla of the fallopian tube (C)</p> Signup and view all the answers

A 38-year-old female with a history of pelvic inflammatory disease (PID) and previous tubal surgery presents with amenorrhea, vaginal bleeding, and right lower quadrant abdominal pain. Which of the following conditions should be HIGHLY suspected?

<p>Ectopic pregnancy (C)</p> Signup and view all the answers

A patient is diagnosed with a complete hydatidiform mole. What is the MOST appropriate initial treatment?

<p>Dilation and curettage (D&amp;C) (D)</p> Signup and view all the answers

Which of the following serum progesterone levels would suggest a nonviable pregnancy?

<p>$&lt;5 ng/mL$ (D)</p> Signup and view all the answers

A 36-year-old female presents with vaginal bleeding, a uterus larger than expected for her gestational age, and absence of fetal heart tones. Her quantitative beta-hCG is >100,000 mU/mL. Which of the following ultrasound findings is MOST suggestive of a complete hydatidiform mole?

<p>“Snowstorm” or “cluster of grapes” appearance with no visible embryo (A)</p> Signup and view all the answers

A 28-year-old woman is diagnosed with a partial hydatidiform mole. Which of the following is the recommended initial management?

<p>Dilation and curettage (D&amp;C) with suction curettage (C)</p> Signup and view all the answers

Following evacuation of a complete hydatidiform mole, which of the following monitoring protocols is MOST crucial?

<p>Serial quantitative beta-hCG levels (B)</p> Signup and view all the answers

A 30-year-old patient who recently had a complete hydatidiform mole evacuated is asking about future pregnancies. What is the MOST appropriate recommendation regarding contraception?

<p>Contraception is recommended for 1 year to avoid pregnancy (D)</p> Signup and view all the answers

Which of the following scenarios presents the HIGHEST risk of developing gestational trophoblastic neoplasia (GTN)?

<p>Patient who had a Complete hydatidiform mole (C)</p> Signup and view all the answers

A 40-year-old woman is diagnosed with gestational trophoblastic neoplasia (GTN) following a complete hydatidiform mole. She has persistent elevated beta-hCG levels despite D&C. Which of the following is the MOST appropriate next step in management?

<p>Single-agent chemotherapy (D)</p> Signup and view all the answers

A 25-year-old RhD-negative woman undergoes D&C for a suspected complete hydatidiform mole. What additional intervention should be considered after the procedure?

<p>Administer Rho(D) immune globulin (C)</p> Signup and view all the answers

A 32-year-old patient presents with symptoms suggestive of hyperthyroidism, including tachycardia, warm skin, and tremors, during the second trimester of a pregnancy that was later diagnosed as a complete hydatidiform mole. What is the underlying mechanism MOST likely contributing to these symptoms?

<p>Cross-reactivity of extremely high beta-hCG levels with TSH receptors (C)</p> Signup and view all the answers

A 24-year-old G1P0 presents to the clinic complaining of vaginal bleeding and abdominal cramping. She reports that her last menstrual period was approximately 8 weeks ago, but she has not had a positive pregnancy test. Which of the following is the MOST important next step in evaluating this patient?

<p>Obtain a urine pregnancy test and a quantitative serum beta-hCG level. (B)</p> Signup and view all the answers

Which of the following signs or symptoms is LEAST likely to be associated with a spontaneous abortion?

<p>Severe lower back pain radiating down the legs. (C)</p> Signup and view all the answers

A 32-year-old G2P1 presents to the emergency department with complaints of severe abdominal pain and vaginal bleeding. She reports a history of a previous ectopic pregnancy treated with salpingectomy. Her vital signs are stable. A bedside ultrasound reveals no intrauterine pregnancy, and a moderate amount of free fluid in the cul-de-sac is noted. Her beta-hCG level is 1500 mIU/mL. What is the MOST appropriate next step in management?

<p>Order a complete blood count and coagulation studies, and prepare for possible exploratory laparotomy. (A)</p> Signup and view all the answers

A patient experiencing early pregnancy loss at 7 weeks gestation reports passing a large amount of tissue at home and is now experiencing heavy bleeding. Upon examination, the cervical os is open, and tissue is visible. Vital signs are stable. What is the MOST appropriate next step in management?

<p>Immediately perform a dilation and curettage (D&amp;C) to evacuate the remaining uterine contents. (D)</p> Signup and view all the answers

A 26-year-old G1P0 presents with a suspected ectopic pregnancy. Her beta-hCG is 1800 mIU/mL. Transvaginal ultrasound reveals no intrauterine pregnancy, and a 1.5 cm adnexal mass is seen. She is hemodynamically stable and reports minimal pain. Which of the following factors would be an ABSOLUTE contraindication to methotrexate therapy?

<p>The patient is breastfeeding. (A)</p> Signup and view all the answers

A 29-year-old G1P0 presents to the emergency department complaining of vaginal bleeding and lower abdominal pain. She reports that she is approximately 8 weeks pregnant based on her last menstrual period, but she has not had a positive pregnancy test. Besides obtaining a pregnancy test, which of the following is the MOST crucial next initial step in evaluating this patient?

<p>Performing a pelvic exam to assess cervical dilation and bleeding source (A)</p> Signup and view all the answers

Which of the following signs and symptoms would be LEAST likely associated with a spontaneous abortion?

<p>Severe lower back pain radiating to the legs (C)</p> Signup and view all the answers

A 35-year-old female presents to the clinic complaining of vaginal bleeding and right-sided abdominal pain. She reports a positive pregnancy test 6 weeks ago based on her last menstrual period but has not had an ultrasound. She denies any prior history of ectopic pregnancy or pelvic inflammatory disease. Her vital signs are stable. A bedside ultrasound reveals no intrauterine pregnancy. Her beta-hCG level is 1,200 mIU/mL. Which of the following diagnoses is LEAST likely on the differential?

<p>Viable intrauterine pregnancy (A)</p> Signup and view all the answers

A patient at 10 weeks gestation presents with heavy vaginal bleeding, severe abdominal cramping, and passage of grape-like vesicles. Her beta-hCG level is significantly elevated. Which of the following conditions is MOST likely?

<p>Complete hydatidiform mole (B)</p> Signup and view all the answers

A 28-year-old female presents to the emergency department with severe lower abdominal pain and vaginal bleeding. She reports a history of irregular menstrual cycles and has not had a positive pregnancy test. On examination, she has significant abdominal tenderness, and her vital signs are stable. A bedside ultrasound reveals no intrauterine pregnancy and a small amount of free fluid in the cul-de-sac. Her beta-hCG level is 1,000 mIU/mL. What is the MOST appropriate next step in management?

<p>Administering methotrexate (A)</p> Signup and view all the answers

A patient at 8 weeks gestation presents to the clinic with mild vaginal spotting and lower abdominal cramping. On examination, the cervical os is closed, and the ultrasound reveals a viable intrauterine pregnancy with a fetal heartbeat. What is the MOST likely diagnosis?

<p>Threatened abortion (D)</p> Signup and view all the answers

A 30-year-old female presents to the clinic with a history of irregular menstrual cycles and difficulty conceiving. She reports a positive pregnancy test 5 weeks ago but has now started experiencing vaginal bleeding and lower abdominal pain. An ultrasound reveals no intrauterine pregnancy, and her beta-hCG level is 800 mIU/mL. Which of the following statements is the MOST accurate regarding the next appropriate step in management?

<p>Schedule a repeat beta-hCG level in 48 hours to assess for appropriate doubling and repeat ultrasound (A)</p> Signup and view all the answers

Which of the following is the MOST important risk factor associated with spontaneous abortion in the first trimester?

<p>Maternal age (D)</p> Signup and view all the answers

A 25-year-old G1P0 patient presents to the emergency department complaining of vaginal bleeding that started approximately 2 hours prior to arrival, and abdominal cramping. She reports that her last menstrual period was 7 weeks ago. She denies ever having a positive pregnancy test. On exam you see the cervical os is open. What is the MOST likely type of abortion this patient is experiencing?

<p>Inevitable Abortion (C)</p> Signup and view all the answers

A 32-year-old G2P1 patient presents to the emergency department complaining of severe abdominal pain and vaginal bleeding. She reports a history of missed abortion 6 months prior. She denies any other significant medical history. The patient's vital signs are concerning for hypotension and tachycardia. Pelvic exam reveals a closed cervical os and significant cervical motion tenderness. Which of the following is the MOST concerning finding?

<p>Hypotension and tachycardia (C)</p> Signup and view all the answers

A 19-year-old G0 presents to the ED complaining of bright red vaginal bleeding and abdominal cramping over the last 8 hours. She states she feels pregnant but has not taken a pregnancy test. She believes her LNMP was approximately 12 weeks ago. When considering the initial differential diagnosis, which of the following is the LEAST likely?

<p>Physiologic implantation bleeding (C)</p> Signup and view all the answers

A patient presents with vaginal bleeding, abdominal pain, and the passage of tissue. She reports a history of feeling pregnant but has not had a pregnancy test. Besides obtaining a pregnancy test, which of the following is the MOST critical next step?

<p>Pelvic ultrasound (D)</p> Signup and view all the answers

A patient presents to the emergency department with vaginal bleeding and abdominal pain. Her last menstrual period was approximately 7 weeks ago, and she has not had a positive pregnancy test. The physician suspects an early pregnancy complication. Which test needs to be ordered FIRST?

<p>Quantitative beta-hCG (A)</p> Signup and view all the answers

A 28-year-old G1P0 patient at 9 weeks gestation presents with vaginal bleeding and lower abdominal pain. On examination, the cervical os is closed. An ultrasound reveals a gestational sac with a yolk sac but no visible fetal pole. Beta-hCG levels are declining. Which of the following is the MOST likely diagnosis?

<p>Missed abortion (D)</p> Signup and view all the answers

A 31-year-old female presents with vaginal bleeding, cramping, and passage of tissue. She reports having a positive pregnancy test two weeks prior. Examination reveals an open cervical os with tissue in the cervical canal. Her vital signs are stable. What type of abortion is she MOST likely experiencing?

<p>Incomplete (A)</p> Signup and view all the answers

A 25-year-old female presents to the clinic complaining of vaginal bleeding and abdominal cramping. She reports a positive pregnancy test approximately 6 weeks ago. On examination, the cervical os is closed, and the ultrasound reveals a viable intrauterine pregnancy. What is the MOST appropriate next step in management??

<p>Monitor expectantly (D)</p> Signup and view all the answers

Which of the following findings would be LEAST consistent with inevitable abortion?

<p>Closed cervical os (D)</p> Signup and view all the answers

During an evaluation for early pregnancy loss, a patient's beta-hCG level is 1,500 mIU/mL. A transvaginal ultrasound fails to visualize an intrauterine pregnancy. What is the MOST appropriate next step?

<p>Repeat beta-hCG in 48 hours (C)</p> Signup and view all the answers

A 34-year-old patient presents with a history of vaginal bleeding and the passage of tissue. Ultrasound confirms the presence of some, but not all, products of conception in the uterus. What is the MOST appropriate diagnosis?

<p>Incomplete abortion (D)</p> Signup and view all the answers

A patient presents to the emergency department complaining of vaginal bleeding and abdominal pain. She reports that her last menstrual period was 6 weeks ago and had a positive pregnancy test 1 week prior. She denies passing any tissue. On examination, the cervical os is closed. The patient is hemodynamically stable. An ultrasound reveals an intrauterine pregnancy. Which of the following is the MOST likely diagnosis?

<p>Threatened abortion (B)</p> Signup and view all the answers

What is the primary objective when managing preterm labor?

<p>Preventing delivery (B)</p> Signup and view all the answers

Which of the following is LEAST likely a neonatal consequence of preterm delivery?

<p>Shoulder dystocia (B)</p> Signup and view all the answers

What is the primary concern regarding premature rupture of membranes (PROM)?

<p>Intrauterine infection (A)</p> Signup and view all the answers

What is the significance of the discriminatory zone in the context of ectopic pregnancy?

<p>hCG level thresholds (C)</p> Signup and view all the answers

In Rh alloimmunization, what fetal condition results in severe edema and fluid accumulation?

<p>Hydrops fetalis (D)</p> Signup and view all the answers

What is the Kleihauer-Betke test used for in the context of Rh-negative pregnancies?

<p>Maternal hemorrhage (B)</p> Signup and view all the answers

What is the most immediate risk associated with placenta abruptio?

<p>Fetal demise (A)</p> Signup and view all the answers

In the management of placenta previa, what is the primary determinant of the delivery method?

<p>Placental location (D)</p> Signup and view all the answers

What laboratory finding is most indicative of significant postpartum hemorrhage?

<p>Decreased fibrinogen (B)</p> Signup and view all the answers

Which clinical scenario would MOST strongly suggest the need for Anti-D immune globulin administration?

<p>Rh- mom, Rh+ baby (A)</p> Signup and view all the answers

Preterm labor is clinically defined as regular uterine contractions occurring between which gestational age ranges?

<p>Greater than 20 0/7 weeks and less than 37 0/7 weeks. (A)</p> Signup and view all the answers

Which of the following maternal factors is considered a risk factor for preterm labor?

<p>History of Short Interpregnancy Interval (A)</p> Signup and view all the answers

Which class of medications is NOT typically used in the management of preterm labor according to the provided information?

<p>Opioid analgesics (A)</p> Signup and view all the answers

Corticosteroids are administered to women in preterm labor to accelerate fetal lung maturity. Which of the following corticosteroid regimens involves a total of four doses?

<p>Dexamethasone 6mg IM every 12 hours (B)</p> Signup and view all the answers

Which of the following is a potential neonatal consequence specifically associated with preterm delivery?

<p>Retinopathy of Prematurity (D)</p> Signup and view all the answers

Respiratory Distress Syndrome (RDS) in neonates is primarily caused by a deficiency of which substance?

<p>Surfactant (C)</p> Signup and view all the answers

Which of the following interventions is a primary treatment strategy for Respiratory Distress Syndrome (RDS) in neonates?

<p>Surfactant replacement therapy (C)</p> Signup and view all the answers

A 28-year-old pregnant woman at 32 weeks gestation, with a history of smoking and a prior preterm birth at 34 weeks, presents with regular uterine contractions and documented cervical change. Considering her risk factors and presentation, which initial management strategy directly targets the acceleration of fetal lung maturity and is most beneficial for neonatal outcomes in this preterm scenario?

<p>Initiate Betamethasone administration intramuscularly. (B)</p> Signup and view all the answers

What is the standard intramuscular dose of Anti-D immune globulin given to Rh-negative mothers?

<p>300 μg or 1500 IU (B)</p> Signup and view all the answers

A 35-year-old G1P0 woman at 36 weeks gestation presents with leakage of clear fluid. She denies contractions or bleeding. What is an appropriate diagnostic test to confirm spontaneous rupture of membranes (SROM)?

<p>Nitrazine test (B)</p> Signup and view all the answers

Which of the following is considered a risk factor for PROM?

<p>Polyhydramnios (D)</p> Signup and view all the answers

A 17-year-old G1 female at 34 weeks gestation presents with lower abdominal cramping and lower back pain. She reports 3-5 contractions per hour. Examination reveals the cervix is 1 cm dilated and 60% effaced. What is the MOST immediate concern in the management of this patient?

<p>Preventing preterm delivery (B)</p> Signup and view all the answers

Which of the following is a potential complication associated with PROM?

<p>Placental abruption (A)</p> Signup and view all the answers

In cases of confirmed PREMATURE RUPTURE OF MEMBRANES (PROM) without active labor, what medication is administered to the mother to help accelerate fetal lung maturity?

<p>Betamethasone (C)</p> Signup and view all the answers

Which test, when positive, is MOST indicative of the presence of amniotic fluid?

<p>Nitrazine test (D)</p> Signup and view all the answers

A patient at 30 weeks gestation presents with PPROM. After administering corticosteroids, which of the following management strategies would be MOST appropriate?

<p>Expectant management with close monitoring (C)</p> Signup and view all the answers

Which of the following neonatal complications is MOST directly associated with chronic oligohydramnios resulting from prolonged PPROM before 26 weeks gestation?

<p>Pulmonary hypoplasia (C)</p> Signup and view all the answers

A previously unsensitized Rh-negative woman delivers a healthy Rh-positive baby at term. Assuming standard protocols are followed, when should the mother receive Rh immune globulin to prevent alloimmunization?

<p>Within 72 hours postpartum (D)</p> Signup and view all the answers

A patient presents with abdominal pain, vaginal bleeding, and a positive pregnancy test. Her quantitative serum hCG is 3,000 mIU/mL. Transvaginal ultrasound shows no intrauterine pregnancy. Which of the following is the MOST likely diagnosis, considering the discriminatory zone?

<p>Ectopic pregnancy (C)</p> Signup and view all the answers

A patient with a history of pelvic inflammatory disease presents with left lower quadrant abdominal pain, vaginal spotting, and a positive pregnancy test. Her last menstrual period was 6 weeks ago. Transvaginal ultrasound reveals an empty uterus. The quantitative beta-hCG level is 1800 mIU/mL. Which of the following management options is MOST appropriate?

<p>Perform diagnostic laparoscopy or laparotomy (C)</p> Signup and view all the answers

In the context of ectopic pregnancy, what does the 'discriminatory zone' refer to concerning serum hCG levels?

<p>The range of hCG levels at which an intrauterine pregnancy should be consistently visible on ultrasound (B)</p> Signup and view all the answers

A 28-year-old female presents to the emergency department complaining of right lower quadrant abdominal pain and vaginal bleeding. She reports a positive pregnancy test one week ago. Her vital signs are stable. Transvaginal ultrasound reveals an empty uterus. Her beta-hCG level is 1600 mIU/mL. Considering the location of most ectopic pregnancies, where is the MOST likely location of this pregnancy?

<p>Fallopian tube (C)</p> Signup and view all the answers

A patient experienced a prior ectopic pregnancy treated with salpingectomy and is now presenting with symptoms suggestive of another ectopic pregnancy. The physician is considering both methotrexate and surgical management. Which of the following factors would MOST strongly favor surgical management over methotrexate in this scenario?

<p>Ultrasound reveals a ruptured ectopic pregnancy with hemoperitoneum (D)</p> Signup and view all the answers

Which of the following is the MOST critical concern regarding premature rupture of membranes (PROM)?

<p>Risk of infection (C)</p> Signup and view all the answers

A patient with two prior cesarean sections presents with painless vaginal bleeding at 32 weeks gestation. Ultrasound reveals the placenta completely covering the internal cervical os. Which condition is MOST likely?

<p>Total placenta previa (B)</p> Signup and view all the answers

During the third stage of labor, an Rh-negative mother is exposed to fetal Rh-positive blood. Which of the following is NOT an event that may lead to alloimmunization in this scenario?

<p>Spontaneous vaginal delivery without complications (D)</p> Signup and view all the answers

A fetus experiencing hemolytic disease due to Rh alloimmunization is at risk for developing immune hydrops fetalis. What is the primary mechanism leading to this condition?

<p>Destruction of fetal red blood cells leading to severe anemia and cardiac failure (A)</p> Signup and view all the answers

A 28-year-old Rh-negative (Rh-) woman delivers a healthy Rh-positive (Rh+) baby. She did not receive Rh immunoglobulin during her pregnancy. When should she receive Rh immunoglobulin to prevent alloimmunization?

<p>Within 72 hours postpartum (B)</p> Signup and view all the answers

In Rh genetics, if both parents are Rh-positive (Rh+), what is the likelihood that their child will be Rh-negative (Rh-)?

<p>25% (A)</p> Signup and view all the answers

Cord compression is most likely associated with?

<p>Vasa Previa (B)</p> Signup and view all the answers

A 30-year-old G1P0 presents with vaginal bleeding and is diagnosed with placenta previa at 28 weeks gestation. Which of the following instructions should be given to the patient?

<p>Pelvic rest: Refrain from sexual intercourse. (C)</p> Signup and view all the answers

Which of the following ultrasound findings is MOST suggestive of placenta accreta spectrum?

<p>Loss of the retroplacental clear space. (A)</p> Signup and view all the answers

A 32-year-old G3P2 presents at 35 weeks gestation with painless vaginal bleeding. Ultrasound confirms placenta previa. She is hemodynamically stable and not in labor. Which of the following is the MOST appropriate next step in management?

<p>Admit for inpatient monitoring, administer betamethasone, and plan for delivery at 36-37 weeks gestation. (A)</p> Signup and view all the answers

A 30-year-old female, G2P1, presents to the emergency department complaining of lower abdominal pain and vaginal bleeding. She states she is approximately 7 weeks pregnant based on her last menstrual period. Her vital signs are stable. Transvaginal ultrasound reveals no intrauterine pregnancy, and the adnexa are difficult to visualize due to patient discomfort. Her beta-hCG level is 1,800 mIU/mL. Which of the following is the MOST appropriate next step in managing this patient?

<p>Repeat beta-hCG in 48 hours and repeat ultrasound (B)</p> Signup and view all the answers

Which of the following patient profiles is MOST likely to develop an ectopic pregnancy?

<p>A 28-year-old with a history of pelvic inflammatory disease (PID) (A)</p> Signup and view all the answers

A hemodynamically stable patient is diagnosed with an ectopic pregnancy and has a beta-hCG level of 800 mIU/mL. An ultrasound reveals a 2 cm unruptured ectopic mass. Which of the following is the MOST appropriate initial treatment option?

<p>Methotrexate administration (B)</p> Signup and view all the answers

Which of the following findings would be MOST concerning in a patient presenting with painless bright red vaginal bleeding at 28 weeks gestation?

<p>Repetitive late decelerations on fetal monitoring (B)</p> Signup and view all the answers

Which of the following factors is LEAST associated with an increased risk of postpartum hemorrhage (PPH)?

<p>Small for gestational age infant (A)</p> Signup and view all the answers

Which of the following is the MOST appropriate first-line intervention for uterine atony resulting in postpartum hemorrhage after vaginal delivery?

<p>Bimanual uterine massage (A)</p> Signup and view all the answers

A 26-year-old G1P0 Rh-negative woman delivers a healthy, Rh-positive infant. She received Rhogam at 28 weeks gestation. However, a large fetal-maternal hemorrhage is suspected. Which of the following is the MOST appropriate next step to determine the correct dose of Anti-D immune globulin?

<p>Kleihauer-Betke test (D)</p> Signup and view all the answers

A 35-year-old G3P2 woman at 32 weeks gestation presents with painless vaginal bleeding. Ultrasound reveals a placenta completely covering the internal cervical os. Which of the following is the MOST appropriate management approach?

<p>Expectant management with pelvic rest and planned cesarean delivery (D)</p> Signup and view all the answers

Which of the following is the MOST critical factor to consider when determining the route of delivery (vaginal vs. cesarean) in a patient diagnosed with placenta previa?

<p>Degree to which the placenta covers the internal cervical os (A)</p> Signup and view all the answers

A 24-year-old G1P0 presents at 26 weeks gestation complaining of a gush of fluid from her vagina approximately 2 hours ago. On examination, you note pooling of clear fluid in the posterior fornix, and a nitrazine test is positive. Ferning is also noted. Which of the following is the MOST appropriate next step in management, assuming there are no signs of infection, labor, or fetal distress?

<p>Administration of antibiotics and corticosteroids (C)</p> Signup and view all the answers

A patient presents with vaginal bleeding, abdominal pain, and reports passing tissue. The patient has NOT taken a pregnancy test, so, besides that, what is the MOST critical next step?

<p>Speculum examination (D)</p> Signup and view all the answers

A 17-year-old, G0 presents with a primary complaint of bright red vaginal bleeding and abdominal cramping of 6 hours duration. The patient reports feeling pregnant, but with no pregnancy test accomplished. Believes her LNMP was 3+ months ago, and the PMH and surgical history are non-contributory. Which of the following is the LEAST likely diagnosis?

<p>Complete abortion (A)</p> Signup and view all the answers

A 32-year-old G2P1 patient presents to the emergency department complaining of severe abdominal pain and vaginal bleeding. She reports a history of missed abortion 6 months prior. She denies any other significant medical history. The patient's vital signs show hypotension and tachycardia. Pelvic exam reveals a closed cervical os and significant cervical motion tenderness. Which of the following is the MOST concerning finding?

<p>Hemodynamic instability (C)</p> Signup and view all the answers

A patient presents with vaginal bleeding, abdominal pain, and the passage of tissue. The patient gives a history of feeling pregnant, despite the lack of a pregnancy test. Besides obtaining a pregnancy test, which of the following is the MOST critical next step?

<p>Speculum examination (A)</p> Signup and view all the answers

At which gestational age does spontaneous abortion typically occur?

<p>Before 20 weeks (D)</p> Signup and view all the answers

A patient tests for serum beta-hCG, and the level is 1,500 mIU/mL. A transvaginal ultrasound fails to visualize an intrauterine pregnancy. What is the MOST appropriate next step?

<p>Repeat hCG in 48 hours (D)</p> Signup and view all the answers

A 34-year-old patient presents with both vaginal bleeding and the passage of tissue. Ultrasound confirms the presence of some, but not all, products of conception in the uterus. What is the MOST appropriate diagnosis?

<p>Incomplete abortion (C)</p> Signup and view all the answers

A patient at 9 weeks gestation presents with vaginal bleeding and the passage of grape-like vesicles. Her beta-hCG level registers significantly elevated. Which condition is MOST likely?

<p>Hydatidiform mole (C)</p> Signup and view all the answers

A 28-year-old female presents to the emergency department complaining of severe lower abdominal pain and vaginal bleeding. She reports a history of irregular menstrual cycles and has not had a positive pregnancy test. On examination, she has significant abdominal tenderness. Her vital signs are stable. A bedside ultrasound reveals no intrauterine pregnancy and a small amount of free fluid in the cul-de-sac. Her beta-hCG level registers 1,000 mIU/mL. What is the MOST appropriate next step in management?

<p>Serial hCG measurements (C)</p> Signup and view all the answers

When a patient experiencing early pregnancy loss at 7 weeks gestation reports passing a large amount of tissue at home and is now experiencing heavy bleeding, and the examination reveals an open cervical os with tissue visible, what is the MOST appropriate next step in management?

<p>Surgical uterine evacuation (C)</p> Signup and view all the answers

A patient presents with vaginal bleeding, abdominal pain, and passage of tissue. The patient has felt pregnant but never took a pregnancy test. Besides ordering a pregnancy test, what is the MOST critical next step?

<p>Ultrasound evaluation (D)</p> Signup and view all the answers

A 17-year-old, G0 presents with a primary complaint of bright red vaginal bleeding and abdominal cramping of 6 hours duration. The patient reports feeling pregnant, but states her LNMP was 3+ months ago, and no pregnancy test was accomplished. PMH and surgical history are non-contributory. Which of the following is the LEAST likely diagnosis?

<p>Placenta previa (A)</p> Signup and view all the answers

What symptoms may indicate a spontaneous abortion?

<p>Back pain (A)</p> Signup and view all the answers

A patient presents with bleeding and pain. What type of pregnancy can cause bleeding?

<p>Molar (C)</p> Signup and view all the answers

Vaginal bleeding and abdominal pain can occur in which of the following non-viable pregnancy condition?

<p>Ectopic (C)</p> Signup and view all the answers

The passing of a pregnancy at ________ weeks is considered a spontaneous abortion.

<p>20 (D)</p> Signup and view all the answers

What is a symptom of spontaneous abortion mentioned?

<p>Low back pain (C)</p> Signup and view all the answers

What is considered an abnormality in pregnancies in reference to this presentation?

<p>Abdominal Pain (A)</p> Signup and view all the answers

Spontaneous abortion is defined as the passing of a pregnancy at less than _____ weeks gestation?

<p>20 (B)</p> Signup and view all the answers

A 17-year-old, G0 presents with a 6-hour history of bright red vaginal bleeding and abdominal cramping. She reports feeling pregnant, but has not taken a pregnancy test. The patient probably has which condition?

<p>Abortion (B)</p> Signup and view all the answers

Which symptom is LEAST associated with spontaneous abortion?

<p>Weight gain (C)</p> Signup and view all the answers

Bright red vaginal bleeding and abdominal cramping are most indicative of _____.

<p>Spontaneous abortion (D)</p> Signup and view all the answers

The MOST common symptoms of early pregnancy abnormalities include vaginal __________ and abdominal __________.

<p>Bleeding, pain (B)</p> Signup and view all the answers

In a non-viable intrauterine pregnancy, which of the following is UNLIKELY?

<p>Fetal movement (D)</p> Signup and view all the answers

Which condition may present with vaginal bleeding but is NOT an abortion?

<p>Ectopic (A)</p> Signup and view all the answers

Which type of bleeding in early pregnancy is generally considered benign?

<p>Subchorionic (C)</p> Signup and view all the answers

Loss of pregnancy symptoms is suggestive of which condition?

<p>Spontaneous abortion (A)</p> Signup and view all the answers

Symptoms of abortion include vaginal bleeding and what other symptom?

<p>Cramping (D)</p> Signup and view all the answers

Flashcards

Hydatidiform Mole

Also known as a molar pregnancy, it's part of gestational trophoblastic disease (GTD) and occurs after abnormal fertilization.

Gestational Trophoblastic Disease (GTD)

A range of conditions that start in the placenta, marked by unusual growth of placental (trophoblastic) tissue.

Aberrant Fertilization (in Molar Pregnancy)

Occurs when fertilization goes wrong, leading to the development of either a complete or partial molar pregnancy.

Complete Molar Pregnancy

One type of hydatidiform mole.

Signup and view all the flashcards

Partial Molar Pregnancy

One type of hydatidiform mole.

Signup and view all the flashcards

Choriocarcinoma

A malignant tumor originating from trophoblast cells, known for being highly vascular and invasive, often following a complete mole.

Signup and view all the flashcards

Choriocarcinoma Symptoms

Abnormal uterine bleeding and elevated hCG levels are indicators of a possible malignancy.

Signup and view all the flashcards

Ectopic Pregnancy

Ectopic pregnancy is when implantation occurs outside the uterine cavity, most commonly in the fallopian tubes.

Signup and view all the flashcards

Symptoms of Ectopic Pregnancy

Abdominal pain, vaginal bleeding, and possible cervical motion tenderness may occur.

Signup and view all the flashcards

Ruptured Ectopic Pregnancy Symptoms

Severe abdominal or shoulder pain with peritonitis, syncope, orthostatic hypotension are indications.

Signup and view all the flashcards

Hydatidiform Mole (Molar Pregnancy)

Most common, usually benign form of GTD. Characterized by abnormal placental development.

Signup and view all the flashcards

Invasive Mole

Molar pregnancy that extends into the uterine wall or vagina.

Signup and view all the flashcards

Complete Hydatidiform Mole

No fetal tissue present, fertilization of an egg with no DNA.

Signup and view all the flashcards

Partial Hydatidiform Mole

Fetal tissue present along with molar degeneration; fertilization of normal egg with two sperm.

Signup and view all the flashcards

Diagnosis of Complete Mole

"Snowstorm" or "cluster of grapes" appearance on ultrasound, very high beta-hCG levels.

Signup and view all the flashcards

Treatment for Hydatidiform Mole

D&C with suction curettage, serial beta-hCG monitoring, contraception for 1 year.

Signup and view all the flashcards

Spontaneous Abortion

Passing of a pregnancy.

Signup and view all the flashcards

Vaginal Bleeding and Abdominal Pain

A common presentation in early pregnancy that may indicate various conditions.

Signup and view all the flashcards

Symptoms Reported by Patient

Bright red vaginal bleeding and abdominal cramping

Signup and view all the flashcards

Signs and Symptoms of Abortion

Vaginal bleeding, cramping/pain, tissue/fluid passage, loss of pregnancy symptoms, back pain.

Signup and view all the flashcards

Sub-chorionic Hemorrhage

A possible cause of vaginal bleeding in early pregnancy.

Signup and view all the flashcards

Obstetrics

A branch of medicine that deals with the care of women during pregnancy, childbirth, and the postpartum period.

Signup and view all the flashcards

Objectives of Obstetrics Study

To understand common complications and their treatment during pregnancy.

Signup and view all the flashcards

Key Obstetric Topics

Conditions include spontaneous abortion, hemorrhage, isoimmunization, GTD, ectopic pregnancy, PROM, and preterm labor.

Signup and view all the flashcards

Early Pregnancy Abnormalities

Includes vaginal bleeding and/or abdominal pain.

Signup and view all the flashcards

Non-Viable Pregnancy

Pregnancy that is not expected to result in a live birth.

Signup and view all the flashcards

Viable Intra-Uterine Pregnancy

Pregnancy with the potential to result in a live birth

Signup and view all the flashcards

Molar Pregnancy

Pregnancy characterized by abnormal placental development.

Signup and view all the flashcards

Physiologic Implantation Bleeding

Normal bleeding that occurs when the embryo implants in the uterus.

Signup and view all the flashcards

Patient Symptoms

Bright red vaginal bleeding and abdominal cramping.

Signup and view all the flashcards

Preterm Labor

Gestational age between 20 0/7 and 37 0/7 weeks with regular uterine contractions and cervical changes.

Signup and view all the flashcards

Risk Factors for Preterm Labor

Previous preterm birth, short interpregnancy interval, vaginal bleeding, UTI, low BMI, smoking, alcohol use, short cervical length, cervical surgery.

Signup and view all the flashcards

Preterm Labor Management (Pharmacological)

Calcium channel blockers, beta-adrenergic receptor agonists, NSAIDs, Magnesium Sulfate.

Signup and view all the flashcards

Preterm Labor: Non-Pharmacological Management

Bedrest and corticosteroids (Betamethasone or Dexamethasone) to accelerate fetal lung maturity.

Signup and view all the flashcards

Neonatal Consequences of Preterm Delivery

Respiratory distress, infection, intraventricular hemorrhage, retinopathy of prematurity.

Signup and view all the flashcards

Respiratory Distress Syndrome (RDS)

Also known as Hyaline membrane disease caused by a lack of surfactant in the lungs.

Signup and view all the flashcards

Respiratory Distress Syndrome (RDS) Treatment

Surfactant replacement therapy and continuous positive airway pressure (CPAP).

Signup and view all the flashcards

Tocolytics

Medications that can be used to suppress or stop uterine contractions in preterm labor.

Signup and view all the flashcards

Hemolytic Disease of the Newborn (HDN)

Caused by incompatibility between mother and fetus blood types, leading to the destruction of fetal red blood cells.

Signup and view all the flashcards

Complications of HDFN

Anemia, cardiac issues, jaundice, and potential brain damage (kernicterus).

Signup and view all the flashcards

Phototherapy (for HDFN)

Light therapy used to reduce bilirubin levels in newborns.

Signup and view all the flashcards

Anti-D Immune Globulin Mechanism

Given to Rh-negative mothers to prevent alloimmunization by binding to fetal Rh-positive red blood cells.

Signup and view all the flashcards

Anti-D Immune Globulin Timing

Administered to D-negative mothers at 28 weeks of gestation and postpartum if the baby is D-positive.

Signup and view all the flashcards

Premature Rupture of Membranes (PROM)

Rupture of membranes at or beyond 37 weeks gestation before the onset of labor.

Signup and view all the flashcards

Preterm Premature Rupture of Membranes (PPROM)

Rupture of membranes before 37 weeks gestation.

Signup and view all the flashcards

PROM/PPROM Diagnosis

Nitrazine, Fern, Immunoassay tests and Ultrasound.

Signup and view all the flashcards

PROM/PPROM Complications

Infection, placental abruption, and umbilical cord prolapse.

Signup and view all the flashcards

PROM/PPROM Management

Group B Strep prophylaxis and potential corticosteroids.

Signup and view all the flashcards

Ectopic Pregnancy Risk Factors

Prior ectopic pregnancy, tubal surgery, STIs, or pelvic inflammatory disease.

Signup and view all the flashcards

Ectopic Pregnancy Treatment

Medical (methotrexate) if stable; surgical (salpingectomy/salpingostomy) if unstable.

Signup and view all the flashcards

Postpartum Hemorrhage

Hemorrhage of >1000 ml following delivery of the placenta.

Signup and view all the flashcards

4 Ts of Postpartum Hemorrhage

Tone, trauma, tissue, thrombin.

Signup and view all the flashcards

Causes of Postpartum Hemorrhage

Uterine atony, trauma, retained placental tissue, and blood clotting conditions.

Signup and view all the flashcards

Immediate Management of PPH

Fundal massage, uterotonic agents.

Signup and view all the flashcards

Chief Complaint Case

Bright red vaginal bleeding.

Signup and view all the flashcards

Postpartum Hemorrhage Risk Factors

Overdistention of the uterus, multiple gestations, large baby >4000 gms, and hydramnios.

Signup and view all the flashcards

Trauma Causes of Postpartum Hemorrhage

Perineal laceration, Cervical laceration Anal sphincter, and Uterine rupture.

Signup and view all the flashcards

Discriminatory Zone (hCG)

hCG level range where a transvaginal ultrasound should detect an intrauterine pregnancy (1500-2000 mIU/mL). Transabdominal US range is 5000 – 6500 mIU/mL.

Signup and view all the flashcards

Purpose of Discriminatory Zone

Used to determine if an intrauterine pregnancy should be visible on ultrasound, based on hCG level.

Signup and view all the flashcards

Ectopic Pregnancy Diagnosis

Rule out other conditions based on history, physical exam, hCG levels and ultrasound findings.

Signup and view all the flashcards

Alloimmunization in Pregnancy

A condition where transplacental maternal antibodies destroy fetal erythrocytes, leading to overproduction of immature fetal RBCs.

Signup and view all the flashcards

Rh Genetics

Presence of antigen D = Rhesus positive (Rh+). Absence of antigen D = Rhesus negative (Rh-).

Signup and view all the flashcards

Alloimmunization Process

Maternal exposure to Rh+ fetal blood leads to the production of IgG antibodies against the Rh factor. Subsequent pregnancies are at risk.

Signup and view all the flashcards

Causes of Alloimmunization

Third stage of labor, Cesarean section, Antepartum hemorrhage, Abortion/ectopic pregnancy, Amniocentesis, Abdominal trauma.

Signup and view all the flashcards

Immune Hydrops Fetalis

Hemolytic disease causing anemia, tissue hypoxia, metabolic acidosis, generalized edema, ascites, pleural effusions, and potentially fetal death.

Signup and view all the flashcards

Management of Rh alloimmunization

Involves monitoring with Liley curve and middle cerebral artery Doppler to assess fetal anemia.

Signup and view all the flashcards

PUBS

Percutaneous Umbilical Blood Sampling, a procedure used in the management of Rh alloimmunization.

Signup and view all the flashcards

Placenta Previa

A condition where the placenta either partially or completely covers the cervix.

Signup and view all the flashcards

Diagnosis of Placental Previa

Diagnosis involves ultrasound, including color Doppler, to assess placental location and rule out vasa previa .

Signup and view all the flashcards

Management of Placenta Previa

Avoiding strenuous activity, managing bleeding episodes, and planning for a Cesarean delivery are key steps.

Signup and view all the flashcards

Bleeding & Pain in Early Pregnancy

A common presentation characterized by vaginal bleeding and abdominal pain.

Signup and view all the flashcards

Abortion Symptoms

Bright red vaginal bleeding, cramping/pain in the abdomen, and possible passage of tissue.

Signup and view all the flashcards

Implantation Bleeding

Normal bleeding that occurs when the embryo implants in the uterus.

Signup and view all the flashcards

ED (in OB context)

Emergency Department

Signup and view all the flashcards

LNMP

Last Normal Menstrual Period

Signup and view all the flashcards

Spontaneous Abortion Definition

The expulsion of a pregnancy before fetal viability.

Signup and view all the flashcards

Non-Viable Intra-Uterine Pregnancy

Pregnancies that are inside the uterus but are not able to result in a live birth.

Signup and view all the flashcards

G0

A woman who has never been pregnant.

Signup and view all the flashcards

Typical Abortion Symptoms

Bright red vaginal bleeding with abdominal cramping.

Signup and view all the flashcards

Passage of Tissue/Fluid

Passing tissue or fluid from the vagina, indicating pregnancy loss.

Signup and view all the flashcards

Loss of Pregnancy Symptoms

Reduced or absent signs of pregnancy, like morning sickness.

Signup and view all the flashcards

Back Pain in Abortion

Pain in the lower back that may accompany vaginal bleeding.

Signup and view all the flashcards

Initial Assessment Steps

The initial steps in assessing a patient for a potential miscarriage.

Signup and view all the flashcards

Study Notes

  • G0, 17-year-old presents to the ED with a 6 hour history of bright red vaginal bleeding and abdominal cramping
  • Reports feeling pregnant without taking a pregnancy test.
  • Last menstrual period 3+ months ago.
  • PMH and surgical history are non-contributory.

Types of Abortions

  • Threatened abortion involves bleeding before the 20th completed week in a viable gestation
  • Complete abortion implies that expulsion of all conception products happened before 20 weeks.
  • Incomplete abortion is the incomplete expulsion of conception products before 20 weeks.
  • Inevitable abortion means the cervix is dilated with bleeding before 20 weeks of gestation.
  • Missed abortion refers to a nonviable gestational sac retained without dilation.

Signs and Symptoms of Abortion

  • Include vaginal bleeding, cramping and pain, passage of tissue or fluid and back pain.
  • Other symptoms are loss of pregnancy symptoms

Etiologies of Abortion

  • Genetric factors
  • Advanced Maternal Age
  • Chronic Health Conditions
  • Infections
  • Uterine Abnormalities
  • Exposure to Toxins

Etiologies of Abortion - Genetic Factors

  • Aneuploidy accounts for greater than 50% of early pregnancy losses.
  • Autosomal trisomies are the most commone.
  • Trisomy 16 is very common
  • Monosomy X (45 X) is very common

Diagnosis of Abortion

  • Transvaginal ultrasonography.
  • Quantitative beta-hCG testing.
  • A pelvic examination
  • Type and screen for blood type.
  • Examination of passed tissue

Management of Abortion

  • Suction curettage

Recurrent Abortion

  • Defined as two or more failed pregnancies before '20 weeks gestation'
  • Related to
  • Genetic Factors
  • Uterine Abnormalities
  • Hormonal Factors
  • Immune Disorders

Gestational Trophoblastic Disease (GTD) Symptoms

  • Abnormal uterine bleeding is the most common presenting symptom.
  • The uterus may be larger than expected for gestational age.
  • Nausea and vomiting may require hospitalization.
  • Preeclampsia can show during the first or early second trimester
  • Passage of "grape-like" structures from the vagina.

GTD - Pregnancy

  • 32-year-old G2P1 at 8 weeks presents with severe nausea and vomiting requiring IV hydration
  • Intermittent vaginal bleeding for 3 days with grape-like structures in blood
  • The patient presents with a snowfall pattern on transvaginal ultrasound.

Normal Fertilization

  • The female pronucleus and male pronucleus both have 23 chromosomes.
  • After combining there are 46 total.

Types of Abnormal trophoblast proliferation

Benign:

  • Gestational Trophoblastic Disease (GTD)
  • Hydatidiform Moles
  • Complete Mole & Partial Mole Malignant: Gestational Trophoblastic Neoplasia (GTN)
  • Invasive Moles, Choriocarcinoma, Placental Site, Trophoblastic Tumor.

Alloimmunization in Pregnancy

  • Is marked by transplacental maternal antibodies that destroy fetal erythrocytes
  • Overproduction of immature RBCs marks fetal and neonatal RBCs
  • Can lead to Hemolytic disease of the fetus and newborn (HDFN)
  • CcDEe are main antigens of Rh blood group
  • D is very important Rh antigen

Rh Genetics

  • Antigen D was discovered in Rhesus monkeys in 1940
  • Presence of antigen D = Rhesus positive (Rh+)
  • 65% of Rh+ men are heterozygous (Dd) and 35% are homozygous (dd)
  • The D gene is dominant, DD and Dd are Rh+, and dd is Rh-

Alloimmunization Process

  • Maternal Rh antibodies are IgG, acquired through exposure to Rh+ blood
  • First pregnancy not usually affected
  • In subsequent pregnancies, the mother will already possess IgG antibodies to the Rh factor
  • Fetal hydrops or hemolytic disease of the newborn.

Risk conditions for Alloimmunization

  • Includes third stage of labor, Cesarean section, antepartum and postpartum hemorrhage, abortion/ectopic pregnancy, amniocentesis and chorionic villus sampling, and abdominal trauma.

Result of all immunization - Immune Hydrops Fetalis

  • Leads to Hemolytic disease
  • Causes destruction of fetal red blood cells
  • Hemolytic anemia causes
  • Tissue hypoxia
  • Leads to Metabolic acidosis
  • Generalized edema, ascites, Pleural effusions
  • Can cause Fetal death secondary to cardiac failure

Management of Rh alloimmunization

  • Liley Curve
  • Middle cerebral artery doppler
  • Percutaneous Umbilical Blood Sampling (PUBS)

Result of Severe RH alloimmunization - Hemolytic Disease of the Fetus and Newborn (HDN)

  • Can cause Jaundice and kernicterus.

Complications of Hemolytic Disease of the Fetus and Newborn (HDN)

  • Causes Anemia, Cardiac complications
  • Leads to Hyperbilirubinemia, jaundice, kernicterus
  • Can result in Kernicterus Spectrum Disorder
  • Causes Cerebral Palsy
  • Causes Hearing Loss
  • Causes Vision Problems
  • Causes Cognitive and learning issues

Treatment of Hemolytic Disease of the Fetus and Newborn

  • Phototheraphy

Treatment of Rh Disease

  • Anti-D Immune Globulin, which is derived from individuals with high-titer immunoglobuline D antibodies
  • Given Prophylatically to all D-negative, unsensitized women at 28 weeks and after delivery if newborn is D-positive
  • Given as Standard IM dose of anti-D immune globulin-300 µg or 1500 IU

Premature Rupture of Membranes

  • 35 yo G₁Po, at 36 weeks, presents with leaking clear fluid.
  • Is diagnosed from Nitrazine test, Fern test, Immunoassay (Amnisure) and Ultrasound.
  • PROM, ≥ 37 gestation when membranes rupture prior to onset of labor
  • PPROM, membranes rupture prior to onset of labor before < 37 gestation.

PREMATURE RUPTURE OF MEMBRANES (PROM)

  • Risk factors include Infection Polyhydramnios and Smoking/drugs
  • Complications can be Infection/*endometritis, Placental abruption, Umbilical cord prolapse, leading to Respiratory distress of newborn and can cause Skeletal deformities
  • Management includes treatments for Group B Streptococcus, Corticosteroids and to Montior.

Preterm Labor

  • 17-year-old G₁ at 34 weeks gestation presents with c/o lower abdominal cramping and lower back pain
  • Report feelings of 3-5 contractions per hour and denies vaginal bleeding or rupture of membranes.
  • Cervix is 1 cm and 60% effaced.

Preterm Labor Indicators

  • The is when Gestational age is > 20 0/7 weeks and < 37 0/7 weeks
  • This causes Regular uterine contractions at frequent intervals and documented cervical dilatation or effacement

Risk conditions for preterm Labor

  • History of Preterm birth
  • Short inter pregnancy interval
  • Vaginal Bleeding and Urinary Tract Infections
  • Cervical Surgery
  • Low Maternal BMI
  • Related to smoking and alcohol
  • Short Cervical Length

Preterm birth per race, 2021-2023

  • Black accounts for 14.7% of all preterm births
  • American Indian accounts for 12.1%
  • Hispanic accounts for 10.2%
  • White accounts for 9.8%
  • Asian accounts for 9.2%

Preterm Labor Management

  • Calcium channel blockers
  • Beta-adrenergic receptor agonists
  • NSAID
  • Magnesium Sulfate
  • Bedrest
    • Also treat with Corticosteroids to accelerate fetal lung maturity (between 23 and 34 weeks)
  • Betamethasone, 12mg IM q24hours for total of 2 doses
  • Dexamthasone, 6 mg IM, q12 hours apart for total of 4 doses

Neonatal Consequences of preterm Delivery

  • Causes Respiratory distress
  • Infections
  • Intraventricular hemorrhage
  • Causes Retinopathy of prematurity

Respiratory Distress Syndrome can result from

  • Hyaline membrane disease
  • Caused by a lack of surfactant in the lungs
  • Treated with Surfactant replacement therapy and Continuous positive airway pressure (CPAP)

Spontaneous Abortion

  • Occurs prior to 20 weeks gestation
  • 15-20%
  • 80% in 1st 12 weeks

Risk factors of spontaneous abortion

  • parity
  • increasing maternal/paternal age
  • smoking

S/S: of spontaneous abortion:

  • crampy, Abd pain, fever, pain, bleeding if septic

Threatened abortion

  • vaginal bleeding WITHOUT cervical dilation or passage of tissues -50%

inevitable abortion:

  • ruptures, cervical diliataion: Painful contractions

incomplete abortion:

  • tissue is passed, retained material
  • curettage used to remove conceptions

Complete abortion:

-tissue passed, cervix closed

missed abortion:

  • no/failed heart beat, closed cervix
  • Sxs persistent amenorrhea

Labs spontaneous abortions:

  • high titers, viable pregnancy.
  • blood type

Elective Abortion:

-termined

  • No risk of complications.

Ectopic pregnancy diagnosis

  • physical exam, HCG, ultrasound

Partial/low-lying

  • resolve in 32-35 weeks

Sxs : placenta

-Pain less, resolves.

  • Avoid digital exam

A abruptio placenta sxs :

  • trauma, chronic HTN and smoking. Painful /con, tender.
  • Labs: CBC, fibrin blood type -US evaluation

Management :

-delivery

  • Cautions of bleeding

heterotopic : is

  • extrauterine

Hemolytic

  • RHD IM
  • autoantibodies

Kernicterus

  • 37 weeks
  • heel prick
  • UV. Exchange

Gestational Trophoblastic Disease (GTD)

  • aka) a molar pregnancy

  • Part of the spectrum of interrelated conditions classified as gestational trophoblastic disease Occurs after aberrant fertilization

  • There's two forms: 1) complete molar pregnancy 2) Partial molar pregnancy

What is it?

  • Spectrum of interrelated conditions originating in the placenta w/ abnormal placental (trophoblastic) proliferation. Types of GTD:

  • Hydatidiform mole (molar pregnancy)- MC presentation usually benign Intrusive -invasive in the uterus Choriocarcinoma malignant transformation

Complete mole

fetal tissue, fertilization of egg w/ no DNA (cells that were meant to become the placenta are abnormal) fetal tissue plus molar degeneration fertilization of normal egg w/ 2 sperm (part of fetus forms cells vaginal size absent hyperthyroidism seen trimes (tachy warm )

Complete Mole:

Ultrason is "snowstorm”, “cluster of grapes”, “Swiss cheese” appearance b/c of absence fetus

Partial Mole:

difficult to do (fetus may be present but growth restricted)

Both:

amniotic fluid

  • Abnorm placenta diameter elev

-S/S of ectopic pregnancy:

  • Amenorrhea, vaginal bleeding, abdominal pain, cervical motion tenderness (and 1/3 of women have adnexal mass on exam)

Studying That Suits You

Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

Quiz Team

More Like This

Gestational Trophoblastic Disease (GTD)
38 questions
Hydatidiform Mole in Second Trimester
20 questions
Use Quizgecko on...
Browser
Browser