Podcast
Questions and Answers
A hydatidiform mole is also known by what name?
A hydatidiform mole is also known by what name?
- Molar pregnancy (correct)
- Placental carcinoma
- Trophoblastic neoplasia
- Choriocarcinoma variant
Gestational trophoblastic disease (GTD) is characterized by abnormal proliferation of what?
Gestational trophoblastic disease (GTD) is characterized by abnormal proliferation of what?
- Amniotic fluid
- Ovarian follicles
- Endometrial lining
- Trophoblastic (placental) tissue (correct)
Following aberrant fertilization, which condition is most likely to occur, representing a type of gestational trophoblastic disease?
Following aberrant fertilization, which condition is most likely to occur, representing a type of gestational trophoblastic disease?
- Placenta previa
- Abruptio placentae
- Complete molar pregnancy (correct)
- Ectopic pregnancy
Which of the following processes is central to the etiology of both complete and partial molar pregnancies?
Which of the following processes is central to the etiology of both complete and partial molar pregnancies?
A patient is diagnosed with gestational trophoblastic disease (GTD). Histopathological examination reveals widespread villous edema and trophoblastic proliferation with no identifiable embryonic or fetal tissue. Which specific type of GTD is most consistent with these findings?
A patient is diagnosed with gestational trophoblastic disease (GTD). Histopathological examination reveals widespread villous edema and trophoblastic proliferation with no identifiable embryonic or fetal tissue. Which specific type of GTD is most consistent with these findings?
A patient presents with abnormal uterine bleeding and significantly elevated hCG levels. Which condition is MOST likely?
A patient presents with abnormal uterine bleeding and significantly elevated hCG levels. Which condition is MOST likely?
Which of the following is the MOST common location for an ectopic pregnancy?
Which of the following is the MOST common location for an ectopic pregnancy?
A 38-year-old female with a history of pelvic inflammatory disease (PID) and previous tubal surgery presents with amenorrhea, vaginal bleeding, and right lower quadrant abdominal pain. Which of the following conditions should be HIGHLY suspected?
A 38-year-old female with a history of pelvic inflammatory disease (PID) and previous tubal surgery presents with amenorrhea, vaginal bleeding, and right lower quadrant abdominal pain. Which of the following conditions should be HIGHLY suspected?
A patient is diagnosed with a complete hydatidiform mole. What is the MOST appropriate initial treatment?
A patient is diagnosed with a complete hydatidiform mole. What is the MOST appropriate initial treatment?
Which of the following serum progesterone levels would suggest a nonviable pregnancy?
Which of the following serum progesterone levels would suggest a nonviable pregnancy?
A 36-year-old female presents with vaginal bleeding, a uterus larger than expected for her gestational age, and absence of fetal heart tones. Her quantitative beta-hCG is >100,000 mU/mL. Which of the following ultrasound findings is MOST suggestive of a complete hydatidiform mole?
A 36-year-old female presents with vaginal bleeding, a uterus larger than expected for her gestational age, and absence of fetal heart tones. Her quantitative beta-hCG is >100,000 mU/mL. Which of the following ultrasound findings is MOST suggestive of a complete hydatidiform mole?
A 28-year-old woman is diagnosed with a partial hydatidiform mole. Which of the following is the recommended initial management?
A 28-year-old woman is diagnosed with a partial hydatidiform mole. Which of the following is the recommended initial management?
Following evacuation of a complete hydatidiform mole, which of the following monitoring protocols is MOST crucial?
Following evacuation of a complete hydatidiform mole, which of the following monitoring protocols is MOST crucial?
A 30-year-old patient who recently had a complete hydatidiform mole evacuated is asking about future pregnancies. What is the MOST appropriate recommendation regarding contraception?
A 30-year-old patient who recently had a complete hydatidiform mole evacuated is asking about future pregnancies. What is the MOST appropriate recommendation regarding contraception?
Which of the following scenarios presents the HIGHEST risk of developing gestational trophoblastic neoplasia (GTN)?
Which of the following scenarios presents the HIGHEST risk of developing gestational trophoblastic neoplasia (GTN)?
A 40-year-old woman is diagnosed with gestational trophoblastic neoplasia (GTN) following a complete hydatidiform mole. She has persistent elevated beta-hCG levels despite D&C. Which of the following is the MOST appropriate next step in management?
A 40-year-old woman is diagnosed with gestational trophoblastic neoplasia (GTN) following a complete hydatidiform mole. She has persistent elevated beta-hCG levels despite D&C. Which of the following is the MOST appropriate next step in management?
A 25-year-old RhD-negative woman undergoes D&C for a suspected complete hydatidiform mole. What additional intervention should be considered after the procedure?
A 25-year-old RhD-negative woman undergoes D&C for a suspected complete hydatidiform mole. What additional intervention should be considered after the procedure?
A 32-year-old patient presents with symptoms suggestive of hyperthyroidism, including tachycardia, warm skin, and tremors, during the second trimester of a pregnancy that was later diagnosed as a complete hydatidiform mole. What is the underlying mechanism MOST likely contributing to these symptoms?
A 32-year-old patient presents with symptoms suggestive of hyperthyroidism, including tachycardia, warm skin, and tremors, during the second trimester of a pregnancy that was later diagnosed as a complete hydatidiform mole. What is the underlying mechanism MOST likely contributing to these symptoms?
A 24-year-old G1P0 presents to the clinic complaining of vaginal bleeding and abdominal cramping. She reports that her last menstrual period was approximately 8 weeks ago, but she has not had a positive pregnancy test. Which of the following is the MOST important next step in evaluating this patient?
A 24-year-old G1P0 presents to the clinic complaining of vaginal bleeding and abdominal cramping. She reports that her last menstrual period was approximately 8 weeks ago, but she has not had a positive pregnancy test. Which of the following is the MOST important next step in evaluating this patient?
Which of the following signs or symptoms is LEAST likely to be associated with a spontaneous abortion?
Which of the following signs or symptoms is LEAST likely to be associated with a spontaneous abortion?
A 32-year-old G2P1 presents to the emergency department with complaints of severe abdominal pain and vaginal bleeding. She reports a history of a previous ectopic pregnancy treated with salpingectomy. Her vital signs are stable. A bedside ultrasound reveals no intrauterine pregnancy, and a moderate amount of free fluid in the cul-de-sac is noted. Her beta-hCG level is 1500 mIU/mL. What is the MOST appropriate next step in management?
A 32-year-old G2P1 presents to the emergency department with complaints of severe abdominal pain and vaginal bleeding. She reports a history of a previous ectopic pregnancy treated with salpingectomy. Her vital signs are stable. A bedside ultrasound reveals no intrauterine pregnancy, and a moderate amount of free fluid in the cul-de-sac is noted. Her beta-hCG level is 1500 mIU/mL. What is the MOST appropriate next step in management?
A patient experiencing early pregnancy loss at 7 weeks gestation reports passing a large amount of tissue at home and is now experiencing heavy bleeding. Upon examination, the cervical os is open, and tissue is visible. Vital signs are stable. What is the MOST appropriate next step in management?
A patient experiencing early pregnancy loss at 7 weeks gestation reports passing a large amount of tissue at home and is now experiencing heavy bleeding. Upon examination, the cervical os is open, and tissue is visible. Vital signs are stable. What is the MOST appropriate next step in management?
A 26-year-old G1P0 presents with a suspected ectopic pregnancy. Her beta-hCG is 1800 mIU/mL. Transvaginal ultrasound reveals no intrauterine pregnancy, and a 1.5 cm adnexal mass is seen. She is hemodynamically stable and reports minimal pain. Which of the following factors would be an ABSOLUTE contraindication to methotrexate therapy?
A 26-year-old G1P0 presents with a suspected ectopic pregnancy. Her beta-hCG is 1800 mIU/mL. Transvaginal ultrasound reveals no intrauterine pregnancy, and a 1.5 cm adnexal mass is seen. She is hemodynamically stable and reports minimal pain. Which of the following factors would be an ABSOLUTE contraindication to methotrexate therapy?
A 29-year-old G1P0 presents to the emergency department complaining of vaginal bleeding and lower abdominal pain. She reports that she is approximately 8 weeks pregnant based on her last menstrual period, but she has not had a positive pregnancy test. Besides obtaining a pregnancy test, which of the following is the MOST crucial next initial step in evaluating this patient?
A 29-year-old G1P0 presents to the emergency department complaining of vaginal bleeding and lower abdominal pain. She reports that she is approximately 8 weeks pregnant based on her last menstrual period, but she has not had a positive pregnancy test. Besides obtaining a pregnancy test, which of the following is the MOST crucial next initial step in evaluating this patient?
Which of the following signs and symptoms would be LEAST likely associated with a spontaneous abortion?
Which of the following signs and symptoms would be LEAST likely associated with a spontaneous abortion?
A 35-year-old female presents to the clinic complaining of vaginal bleeding and right-sided abdominal pain. She reports a positive pregnancy test 6 weeks ago based on her last menstrual period but has not had an ultrasound. She denies any prior history of ectopic pregnancy or pelvic inflammatory disease. Her vital signs are stable. A bedside ultrasound reveals no intrauterine pregnancy. Her beta-hCG level is 1,200 mIU/mL. Which of the following diagnoses is LEAST likely on the differential?
A 35-year-old female presents to the clinic complaining of vaginal bleeding and right-sided abdominal pain. She reports a positive pregnancy test 6 weeks ago based on her last menstrual period but has not had an ultrasound. She denies any prior history of ectopic pregnancy or pelvic inflammatory disease. Her vital signs are stable. A bedside ultrasound reveals no intrauterine pregnancy. Her beta-hCG level is 1,200 mIU/mL. Which of the following diagnoses is LEAST likely on the differential?
A patient at 10 weeks gestation presents with heavy vaginal bleeding, severe abdominal cramping, and passage of grape-like vesicles. Her beta-hCG level is significantly elevated. Which of the following conditions is MOST likely?
A patient at 10 weeks gestation presents with heavy vaginal bleeding, severe abdominal cramping, and passage of grape-like vesicles. Her beta-hCG level is significantly elevated. Which of the following conditions is MOST likely?
A 28-year-old female presents to the emergency department with severe lower abdominal pain and vaginal bleeding. She reports a history of irregular menstrual cycles and has not had a positive pregnancy test. On examination, she has significant abdominal tenderness, and her vital signs are stable. A bedside ultrasound reveals no intrauterine pregnancy and a small amount of free fluid in the cul-de-sac. Her beta-hCG level is 1,000 mIU/mL. What is the MOST appropriate next step in management?
A 28-year-old female presents to the emergency department with severe lower abdominal pain and vaginal bleeding. She reports a history of irregular menstrual cycles and has not had a positive pregnancy test. On examination, she has significant abdominal tenderness, and her vital signs are stable. A bedside ultrasound reveals no intrauterine pregnancy and a small amount of free fluid in the cul-de-sac. Her beta-hCG level is 1,000 mIU/mL. What is the MOST appropriate next step in management?
A patient at 8 weeks gestation presents to the clinic with mild vaginal spotting and lower abdominal cramping. On examination, the cervical os is closed, and the ultrasound reveals a viable intrauterine pregnancy with a fetal heartbeat. What is the MOST likely diagnosis?
A patient at 8 weeks gestation presents to the clinic with mild vaginal spotting and lower abdominal cramping. On examination, the cervical os is closed, and the ultrasound reveals a viable intrauterine pregnancy with a fetal heartbeat. What is the MOST likely diagnosis?
A 30-year-old female presents to the clinic with a history of irregular menstrual cycles and difficulty conceiving. She reports a positive pregnancy test 5 weeks ago but has now started experiencing vaginal bleeding and lower abdominal pain. An ultrasound reveals no intrauterine pregnancy, and her beta-hCG level is 800 mIU/mL. Which of the following statements is the MOST accurate regarding the next appropriate step in management?
A 30-year-old female presents to the clinic with a history of irregular menstrual cycles and difficulty conceiving. She reports a positive pregnancy test 5 weeks ago but has now started experiencing vaginal bleeding and lower abdominal pain. An ultrasound reveals no intrauterine pregnancy, and her beta-hCG level is 800 mIU/mL. Which of the following statements is the MOST accurate regarding the next appropriate step in management?
Which of the following is the MOST important risk factor associated with spontaneous abortion in the first trimester?
Which of the following is the MOST important risk factor associated with spontaneous abortion in the first trimester?
A 25-year-old G1P0 patient presents to the emergency department complaining of vaginal bleeding that started approximately 2 hours prior to arrival, and abdominal cramping. She reports that her last menstrual period was 7 weeks ago. She denies ever having a positive pregnancy test. On exam you see the cervical os is open. What is the MOST likely type of abortion this patient is experiencing?
A 25-year-old G1P0 patient presents to the emergency department complaining of vaginal bleeding that started approximately 2 hours prior to arrival, and abdominal cramping. She reports that her last menstrual period was 7 weeks ago. She denies ever having a positive pregnancy test. On exam you see the cervical os is open. What is the MOST likely type of abortion this patient is experiencing?
A 32-year-old G2P1 patient presents to the emergency department complaining of severe abdominal pain and vaginal bleeding. She reports a history of missed abortion 6 months prior. She denies any other significant medical history. The patient's vital signs are concerning for hypotension and tachycardia. Pelvic exam reveals a closed cervical os and significant cervical motion tenderness. Which of the following is the MOST concerning finding?
A 32-year-old G2P1 patient presents to the emergency department complaining of severe abdominal pain and vaginal bleeding. She reports a history of missed abortion 6 months prior. She denies any other significant medical history. The patient's vital signs are concerning for hypotension and tachycardia. Pelvic exam reveals a closed cervical os and significant cervical motion tenderness. Which of the following is the MOST concerning finding?
A 19-year-old G0 presents to the ED complaining of bright red vaginal bleeding and abdominal cramping over the last 8 hours. She states she feels pregnant but has not taken a pregnancy test. She believes her LNMP was approximately 12 weeks ago. When considering the initial differential diagnosis, which of the following is the LEAST likely?
A 19-year-old G0 presents to the ED complaining of bright red vaginal bleeding and abdominal cramping over the last 8 hours. She states she feels pregnant but has not taken a pregnancy test. She believes her LNMP was approximately 12 weeks ago. When considering the initial differential diagnosis, which of the following is the LEAST likely?
A patient presents with vaginal bleeding, abdominal pain, and the passage of tissue. She reports a history of feeling pregnant but has not had a pregnancy test. Besides obtaining a pregnancy test, which of the following is the MOST critical next step?
A patient presents with vaginal bleeding, abdominal pain, and the passage of tissue. She reports a history of feeling pregnant but has not had a pregnancy test. Besides obtaining a pregnancy test, which of the following is the MOST critical next step?
A patient presents to the emergency department with vaginal bleeding and abdominal pain. Her last menstrual period was approximately 7 weeks ago, and she has not had a positive pregnancy test. The physician suspects an early pregnancy complication. Which test needs to be ordered FIRST?
A patient presents to the emergency department with vaginal bleeding and abdominal pain. Her last menstrual period was approximately 7 weeks ago, and she has not had a positive pregnancy test. The physician suspects an early pregnancy complication. Which test needs to be ordered FIRST?
A 28-year-old G1P0 patient at 9 weeks gestation presents with vaginal bleeding and lower abdominal pain. On examination, the cervical os is closed. An ultrasound reveals a gestational sac with a yolk sac but no visible fetal pole. Beta-hCG levels are declining. Which of the following is the MOST likely diagnosis?
A 28-year-old G1P0 patient at 9 weeks gestation presents with vaginal bleeding and lower abdominal pain. On examination, the cervical os is closed. An ultrasound reveals a gestational sac with a yolk sac but no visible fetal pole. Beta-hCG levels are declining. Which of the following is the MOST likely diagnosis?
A 31-year-old female presents with vaginal bleeding, cramping, and passage of tissue. She reports having a positive pregnancy test two weeks prior. Examination reveals an open cervical os with tissue in the cervical canal. Her vital signs are stable. What type of abortion is she MOST likely experiencing?
A 31-year-old female presents with vaginal bleeding, cramping, and passage of tissue. She reports having a positive pregnancy test two weeks prior. Examination reveals an open cervical os with tissue in the cervical canal. Her vital signs are stable. What type of abortion is she MOST likely experiencing?
A 25-year-old female presents to the clinic complaining of vaginal bleeding and abdominal cramping. She reports a positive pregnancy test approximately 6 weeks ago. On examination, the cervical os is closed, and the ultrasound reveals a viable intrauterine pregnancy. What is the MOST appropriate next step in management??
A 25-year-old female presents to the clinic complaining of vaginal bleeding and abdominal cramping. She reports a positive pregnancy test approximately 6 weeks ago. On examination, the cervical os is closed, and the ultrasound reveals a viable intrauterine pregnancy. What is the MOST appropriate next step in management??
Which of the following findings would be LEAST consistent with inevitable abortion?
Which of the following findings would be LEAST consistent with inevitable abortion?
During an evaluation for early pregnancy loss, a patient's beta-hCG level is 1,500 mIU/mL. A transvaginal ultrasound fails to visualize an intrauterine pregnancy. What is the MOST appropriate next step?
During an evaluation for early pregnancy loss, a patient's beta-hCG level is 1,500 mIU/mL. A transvaginal ultrasound fails to visualize an intrauterine pregnancy. What is the MOST appropriate next step?
A 34-year-old patient presents with a history of vaginal bleeding and the passage of tissue. Ultrasound confirms the presence of some, but not all, products of conception in the uterus. What is the MOST appropriate diagnosis?
A 34-year-old patient presents with a history of vaginal bleeding and the passage of tissue. Ultrasound confirms the presence of some, but not all, products of conception in the uterus. What is the MOST appropriate diagnosis?
A patient presents to the emergency department complaining of vaginal bleeding and abdominal pain. She reports that her last menstrual period was 6 weeks ago and had a positive pregnancy test 1 week prior. She denies passing any tissue. On examination, the cervical os is closed. The patient is hemodynamically stable. An ultrasound reveals an intrauterine pregnancy. Which of the following is the MOST likely diagnosis?
A patient presents to the emergency department complaining of vaginal bleeding and abdominal pain. She reports that her last menstrual period was 6 weeks ago and had a positive pregnancy test 1 week prior. She denies passing any tissue. On examination, the cervical os is closed. The patient is hemodynamically stable. An ultrasound reveals an intrauterine pregnancy. Which of the following is the MOST likely diagnosis?
What is the primary objective when managing preterm labor?
What is the primary objective when managing preterm labor?
Which of the following is LEAST likely a neonatal consequence of preterm delivery?
Which of the following is LEAST likely a neonatal consequence of preterm delivery?
What is the primary concern regarding premature rupture of membranes (PROM)?
What is the primary concern regarding premature rupture of membranes (PROM)?
What is the significance of the discriminatory zone in the context of ectopic pregnancy?
What is the significance of the discriminatory zone in the context of ectopic pregnancy?
In Rh alloimmunization, what fetal condition results in severe edema and fluid accumulation?
In Rh alloimmunization, what fetal condition results in severe edema and fluid accumulation?
What is the Kleihauer-Betke test used for in the context of Rh-negative pregnancies?
What is the Kleihauer-Betke test used for in the context of Rh-negative pregnancies?
What is the most immediate risk associated with placenta abruptio?
What is the most immediate risk associated with placenta abruptio?
In the management of placenta previa, what is the primary determinant of the delivery method?
In the management of placenta previa, what is the primary determinant of the delivery method?
What laboratory finding is most indicative of significant postpartum hemorrhage?
What laboratory finding is most indicative of significant postpartum hemorrhage?
Which clinical scenario would MOST strongly suggest the need for Anti-D immune globulin administration?
Which clinical scenario would MOST strongly suggest the need for Anti-D immune globulin administration?
Preterm labor is clinically defined as regular uterine contractions occurring between which gestational age ranges?
Preterm labor is clinically defined as regular uterine contractions occurring between which gestational age ranges?
Which of the following maternal factors is considered a risk factor for preterm labor?
Which of the following maternal factors is considered a risk factor for preterm labor?
Which class of medications is NOT typically used in the management of preterm labor according to the provided information?
Which class of medications is NOT typically used in the management of preterm labor according to the provided information?
Corticosteroids are administered to women in preterm labor to accelerate fetal lung maturity. Which of the following corticosteroid regimens involves a total of four doses?
Corticosteroids are administered to women in preterm labor to accelerate fetal lung maturity. Which of the following corticosteroid regimens involves a total of four doses?
Which of the following is a potential neonatal consequence specifically associated with preterm delivery?
Which of the following is a potential neonatal consequence specifically associated with preterm delivery?
Respiratory Distress Syndrome (RDS) in neonates is primarily caused by a deficiency of which substance?
Respiratory Distress Syndrome (RDS) in neonates is primarily caused by a deficiency of which substance?
Which of the following interventions is a primary treatment strategy for Respiratory Distress Syndrome (RDS) in neonates?
Which of the following interventions is a primary treatment strategy for Respiratory Distress Syndrome (RDS) in neonates?
A 28-year-old pregnant woman at 32 weeks gestation, with a history of smoking and a prior preterm birth at 34 weeks, presents with regular uterine contractions and documented cervical change. Considering her risk factors and presentation, which initial management strategy directly targets the acceleration of fetal lung maturity and is most beneficial for neonatal outcomes in this preterm scenario?
A 28-year-old pregnant woman at 32 weeks gestation, with a history of smoking and a prior preterm birth at 34 weeks, presents with regular uterine contractions and documented cervical change. Considering her risk factors and presentation, which initial management strategy directly targets the acceleration of fetal lung maturity and is most beneficial for neonatal outcomes in this preterm scenario?
What is the standard intramuscular dose of Anti-D immune globulin given to Rh-negative mothers?
What is the standard intramuscular dose of Anti-D immune globulin given to Rh-negative mothers?
A 35-year-old G1P0 woman at 36 weeks gestation presents with leakage of clear fluid. She denies contractions or bleeding. What is an appropriate diagnostic test to confirm spontaneous rupture of membranes (SROM)?
A 35-year-old G1P0 woman at 36 weeks gestation presents with leakage of clear fluid. She denies contractions or bleeding. What is an appropriate diagnostic test to confirm spontaneous rupture of membranes (SROM)?
Which of the following is considered a risk factor for PROM?
Which of the following is considered a risk factor for PROM?
A 17-year-old G1 female at 34 weeks gestation presents with lower abdominal cramping and lower back pain. She reports 3-5 contractions per hour. Examination reveals the cervix is 1 cm dilated and 60% effaced. What is the MOST immediate concern in the management of this patient?
A 17-year-old G1 female at 34 weeks gestation presents with lower abdominal cramping and lower back pain. She reports 3-5 contractions per hour. Examination reveals the cervix is 1 cm dilated and 60% effaced. What is the MOST immediate concern in the management of this patient?
Which of the following is a potential complication associated with PROM?
Which of the following is a potential complication associated with PROM?
In cases of confirmed PREMATURE RUPTURE OF MEMBRANES (PROM) without active labor, what medication is administered to the mother to help accelerate fetal lung maturity?
In cases of confirmed PREMATURE RUPTURE OF MEMBRANES (PROM) without active labor, what medication is administered to the mother to help accelerate fetal lung maturity?
Which test, when positive, is MOST indicative of the presence of amniotic fluid?
Which test, when positive, is MOST indicative of the presence of amniotic fluid?
A patient at 30 weeks gestation presents with PPROM. After administering corticosteroids, which of the following management strategies would be MOST appropriate?
A patient at 30 weeks gestation presents with PPROM. After administering corticosteroids, which of the following management strategies would be MOST appropriate?
Which of the following neonatal complications is MOST directly associated with chronic oligohydramnios resulting from prolonged PPROM before 26 weeks gestation?
Which of the following neonatal complications is MOST directly associated with chronic oligohydramnios resulting from prolonged PPROM before 26 weeks gestation?
A previously unsensitized Rh-negative woman delivers a healthy Rh-positive baby at term. Assuming standard protocols are followed, when should the mother receive Rh immune globulin to prevent alloimmunization?
A previously unsensitized Rh-negative woman delivers a healthy Rh-positive baby at term. Assuming standard protocols are followed, when should the mother receive Rh immune globulin to prevent alloimmunization?
A patient presents with abdominal pain, vaginal bleeding, and a positive pregnancy test. Her quantitative serum hCG is 3,000 mIU/mL. Transvaginal ultrasound shows no intrauterine pregnancy. Which of the following is the MOST likely diagnosis, considering the discriminatory zone?
A patient presents with abdominal pain, vaginal bleeding, and a positive pregnancy test. Her quantitative serum hCG is 3,000 mIU/mL. Transvaginal ultrasound shows no intrauterine pregnancy. Which of the following is the MOST likely diagnosis, considering the discriminatory zone?
A patient with a history of pelvic inflammatory disease presents with left lower quadrant abdominal pain, vaginal spotting, and a positive pregnancy test. Her last menstrual period was 6 weeks ago. Transvaginal ultrasound reveals an empty uterus. The quantitative beta-hCG level is 1800 mIU/mL. Which of the following management options is MOST appropriate?
A patient with a history of pelvic inflammatory disease presents with left lower quadrant abdominal pain, vaginal spotting, and a positive pregnancy test. Her last menstrual period was 6 weeks ago. Transvaginal ultrasound reveals an empty uterus. The quantitative beta-hCG level is 1800 mIU/mL. Which of the following management options is MOST appropriate?
In the context of ectopic pregnancy, what does the 'discriminatory zone' refer to concerning serum hCG levels?
In the context of ectopic pregnancy, what does the 'discriminatory zone' refer to concerning serum hCG levels?
A 28-year-old female presents to the emergency department complaining of right lower quadrant abdominal pain and vaginal bleeding. She reports a positive pregnancy test one week ago. Her vital signs are stable. Transvaginal ultrasound reveals an empty uterus. Her beta-hCG level is 1600 mIU/mL. Considering the location of most ectopic pregnancies, where is the MOST likely location of this pregnancy?
A 28-year-old female presents to the emergency department complaining of right lower quadrant abdominal pain and vaginal bleeding. She reports a positive pregnancy test one week ago. Her vital signs are stable. Transvaginal ultrasound reveals an empty uterus. Her beta-hCG level is 1600 mIU/mL. Considering the location of most ectopic pregnancies, where is the MOST likely location of this pregnancy?
A patient experienced a prior ectopic pregnancy treated with salpingectomy and is now presenting with symptoms suggestive of another ectopic pregnancy. The physician is considering both methotrexate and surgical management. Which of the following factors would MOST strongly favor surgical management over methotrexate in this scenario?
A patient experienced a prior ectopic pregnancy treated with salpingectomy and is now presenting with symptoms suggestive of another ectopic pregnancy. The physician is considering both methotrexate and surgical management. Which of the following factors would MOST strongly favor surgical management over methotrexate in this scenario?
Which of the following is the MOST critical concern regarding premature rupture of membranes (PROM)?
Which of the following is the MOST critical concern regarding premature rupture of membranes (PROM)?
A patient with two prior cesarean sections presents with painless vaginal bleeding at 32 weeks gestation. Ultrasound reveals the placenta completely covering the internal cervical os. Which condition is MOST likely?
A patient with two prior cesarean sections presents with painless vaginal bleeding at 32 weeks gestation. Ultrasound reveals the placenta completely covering the internal cervical os. Which condition is MOST likely?
During the third stage of labor, an Rh-negative mother is exposed to fetal Rh-positive blood. Which of the following is NOT an event that may lead to alloimmunization in this scenario?
During the third stage of labor, an Rh-negative mother is exposed to fetal Rh-positive blood. Which of the following is NOT an event that may lead to alloimmunization in this scenario?
A fetus experiencing hemolytic disease due to Rh alloimmunization is at risk for developing immune hydrops fetalis. What is the primary mechanism leading to this condition?
A fetus experiencing hemolytic disease due to Rh alloimmunization is at risk for developing immune hydrops fetalis. What is the primary mechanism leading to this condition?
A 28-year-old Rh-negative (Rh-) woman delivers a healthy Rh-positive (Rh+) baby. She did not receive Rh immunoglobulin during her pregnancy. When should she receive Rh immunoglobulin to prevent alloimmunization?
A 28-year-old Rh-negative (Rh-) woman delivers a healthy Rh-positive (Rh+) baby. She did not receive Rh immunoglobulin during her pregnancy. When should she receive Rh immunoglobulin to prevent alloimmunization?
In Rh genetics, if both parents are Rh-positive (Rh+), what is the likelihood that their child will be Rh-negative (Rh-)?
In Rh genetics, if both parents are Rh-positive (Rh+), what is the likelihood that their child will be Rh-negative (Rh-)?
Cord compression is most likely associated with?
Cord compression is most likely associated with?
A 30-year-old G1P0 presents with vaginal bleeding and is diagnosed with placenta previa at 28 weeks gestation. Which of the following instructions should be given to the patient?
A 30-year-old G1P0 presents with vaginal bleeding and is diagnosed with placenta previa at 28 weeks gestation. Which of the following instructions should be given to the patient?
Which of the following ultrasound findings is MOST suggestive of placenta accreta spectrum?
Which of the following ultrasound findings is MOST suggestive of placenta accreta spectrum?
A 32-year-old G3P2 presents at 35 weeks gestation with painless vaginal bleeding. Ultrasound confirms placenta previa. She is hemodynamically stable and not in labor. Which of the following is the MOST appropriate next step in management?
A 32-year-old G3P2 presents at 35 weeks gestation with painless vaginal bleeding. Ultrasound confirms placenta previa. She is hemodynamically stable and not in labor. Which of the following is the MOST appropriate next step in management?
A 30-year-old female, G2P1, presents to the emergency department complaining of lower abdominal pain and vaginal bleeding. She states she is approximately 7 weeks pregnant based on her last menstrual period. Her vital signs are stable. Transvaginal ultrasound reveals no intrauterine pregnancy, and the adnexa are difficult to visualize due to patient discomfort. Her beta-hCG level is 1,800 mIU/mL. Which of the following is the MOST appropriate next step in managing this patient?
A 30-year-old female, G2P1, presents to the emergency department complaining of lower abdominal pain and vaginal bleeding. She states she is approximately 7 weeks pregnant based on her last menstrual period. Her vital signs are stable. Transvaginal ultrasound reveals no intrauterine pregnancy, and the adnexa are difficult to visualize due to patient discomfort. Her beta-hCG level is 1,800 mIU/mL. Which of the following is the MOST appropriate next step in managing this patient?
Which of the following patient profiles is MOST likely to develop an ectopic pregnancy?
Which of the following patient profiles is MOST likely to develop an ectopic pregnancy?
A hemodynamically stable patient is diagnosed with an ectopic pregnancy and has a beta-hCG level of 800 mIU/mL. An ultrasound reveals a 2 cm unruptured ectopic mass. Which of the following is the MOST appropriate initial treatment option?
A hemodynamically stable patient is diagnosed with an ectopic pregnancy and has a beta-hCG level of 800 mIU/mL. An ultrasound reveals a 2 cm unruptured ectopic mass. Which of the following is the MOST appropriate initial treatment option?
Which of the following findings would be MOST concerning in a patient presenting with painless bright red vaginal bleeding at 28 weeks gestation?
Which of the following findings would be MOST concerning in a patient presenting with painless bright red vaginal bleeding at 28 weeks gestation?
Which of the following factors is LEAST associated with an increased risk of postpartum hemorrhage (PPH)?
Which of the following factors is LEAST associated with an increased risk of postpartum hemorrhage (PPH)?
Which of the following is the MOST appropriate first-line intervention for uterine atony resulting in postpartum hemorrhage after vaginal delivery?
Which of the following is the MOST appropriate first-line intervention for uterine atony resulting in postpartum hemorrhage after vaginal delivery?
A 26-year-old G1P0 Rh-negative woman delivers a healthy, Rh-positive infant. She received Rhogam at 28 weeks gestation. However, a large fetal-maternal hemorrhage is suspected. Which of the following is the MOST appropriate next step to determine the correct dose of Anti-D immune globulin?
A 26-year-old G1P0 Rh-negative woman delivers a healthy, Rh-positive infant. She received Rhogam at 28 weeks gestation. However, a large fetal-maternal hemorrhage is suspected. Which of the following is the MOST appropriate next step to determine the correct dose of Anti-D immune globulin?
A 35-year-old G3P2 woman at 32 weeks gestation presents with painless vaginal bleeding. Ultrasound reveals a placenta completely covering the internal cervical os. Which of the following is the MOST appropriate management approach?
A 35-year-old G3P2 woman at 32 weeks gestation presents with painless vaginal bleeding. Ultrasound reveals a placenta completely covering the internal cervical os. Which of the following is the MOST appropriate management approach?
Which of the following is the MOST critical factor to consider when determining the route of delivery (vaginal vs. cesarean) in a patient diagnosed with placenta previa?
Which of the following is the MOST critical factor to consider when determining the route of delivery (vaginal vs. cesarean) in a patient diagnosed with placenta previa?
A 24-year-old G1P0 presents at 26 weeks gestation complaining of a gush of fluid from her vagina approximately 2 hours ago. On examination, you note pooling of clear fluid in the posterior fornix, and a nitrazine test is positive. Ferning is also noted. Which of the following is the MOST appropriate next step in management, assuming there are no signs of infection, labor, or fetal distress?
A 24-year-old G1P0 presents at 26 weeks gestation complaining of a gush of fluid from her vagina approximately 2 hours ago. On examination, you note pooling of clear fluid in the posterior fornix, and a nitrazine test is positive. Ferning is also noted. Which of the following is the MOST appropriate next step in management, assuming there are no signs of infection, labor, or fetal distress?
A patient presents with vaginal bleeding, abdominal pain, and reports passing tissue. The patient has NOT taken a pregnancy test, so, besides that, what is the MOST critical next step?
A patient presents with vaginal bleeding, abdominal pain, and reports passing tissue. The patient has NOT taken a pregnancy test, so, besides that, what is the MOST critical next step?
A 17-year-old, G0 presents with a primary complaint of bright red vaginal bleeding and abdominal cramping of 6 hours duration. The patient reports feeling pregnant, but with no pregnancy test accomplished. Believes her LNMP was 3+ months ago, and the PMH and surgical history are non-contributory. Which of the following is the LEAST likely diagnosis?
A 17-year-old, G0 presents with a primary complaint of bright red vaginal bleeding and abdominal cramping of 6 hours duration. The patient reports feeling pregnant, but with no pregnancy test accomplished. Believes her LNMP was 3+ months ago, and the PMH and surgical history are non-contributory. Which of the following is the LEAST likely diagnosis?
A 32-year-old G2P1 patient presents to the emergency department complaining of severe abdominal pain and vaginal bleeding. She reports a history of missed abortion 6 months prior. She denies any other significant medical history. The patient's vital signs show hypotension and tachycardia. Pelvic exam reveals a closed cervical os and significant cervical motion tenderness. Which of the following is the MOST concerning finding?
A 32-year-old G2P1 patient presents to the emergency department complaining of severe abdominal pain and vaginal bleeding. She reports a history of missed abortion 6 months prior. She denies any other significant medical history. The patient's vital signs show hypotension and tachycardia. Pelvic exam reveals a closed cervical os and significant cervical motion tenderness. Which of the following is the MOST concerning finding?
A patient presents with vaginal bleeding, abdominal pain, and the passage of tissue. The patient gives a history of feeling pregnant, despite the lack of a pregnancy test. Besides obtaining a pregnancy test, which of the following is the MOST critical next step?
A patient presents with vaginal bleeding, abdominal pain, and the passage of tissue. The patient gives a history of feeling pregnant, despite the lack of a pregnancy test. Besides obtaining a pregnancy test, which of the following is the MOST critical next step?
At which gestational age does spontaneous abortion typically occur?
At which gestational age does spontaneous abortion typically occur?
A patient tests for serum beta-hCG, and the level is 1,500 mIU/mL. A transvaginal ultrasound fails to visualize an intrauterine pregnancy. What is the MOST appropriate next step?
A patient tests for serum beta-hCG, and the level is 1,500 mIU/mL. A transvaginal ultrasound fails to visualize an intrauterine pregnancy. What is the MOST appropriate next step?
A 34-year-old patient presents with both vaginal bleeding and the passage of tissue. Ultrasound confirms the presence of some, but not all, products of conception in the uterus. What is the MOST appropriate diagnosis?
A 34-year-old patient presents with both vaginal bleeding and the passage of tissue. Ultrasound confirms the presence of some, but not all, products of conception in the uterus. What is the MOST appropriate diagnosis?
A patient at 9 weeks gestation presents with vaginal bleeding and the passage of grape-like vesicles. Her beta-hCG level registers significantly elevated. Which condition is MOST likely?
A patient at 9 weeks gestation presents with vaginal bleeding and the passage of grape-like vesicles. Her beta-hCG level registers significantly elevated. Which condition is MOST likely?
A 28-year-old female presents to the emergency department complaining of severe lower abdominal pain and vaginal bleeding. She reports a history of irregular menstrual cycles and has not had a positive pregnancy test. On examination, she has significant abdominal tenderness. Her vital signs are stable. A bedside ultrasound reveals no intrauterine pregnancy and a small amount of free fluid in the cul-de-sac. Her beta-hCG level registers 1,000 mIU/mL. What is the MOST appropriate next step in management?
A 28-year-old female presents to the emergency department complaining of severe lower abdominal pain and vaginal bleeding. She reports a history of irregular menstrual cycles and has not had a positive pregnancy test. On examination, she has significant abdominal tenderness. Her vital signs are stable. A bedside ultrasound reveals no intrauterine pregnancy and a small amount of free fluid in the cul-de-sac. Her beta-hCG level registers 1,000 mIU/mL. What is the MOST appropriate next step in management?
When a patient experiencing early pregnancy loss at 7 weeks gestation reports passing a large amount of tissue at home and is now experiencing heavy bleeding, and the examination reveals an open cervical os with tissue visible, what is the MOST appropriate next step in management?
When a patient experiencing early pregnancy loss at 7 weeks gestation reports passing a large amount of tissue at home and is now experiencing heavy bleeding, and the examination reveals an open cervical os with tissue visible, what is the MOST appropriate next step in management?
A patient presents with vaginal bleeding, abdominal pain, and passage of tissue. The patient has felt pregnant but never took a pregnancy test. Besides ordering a pregnancy test, what is the MOST critical next step?
A patient presents with vaginal bleeding, abdominal pain, and passage of tissue. The patient has felt pregnant but never took a pregnancy test. Besides ordering a pregnancy test, what is the MOST critical next step?
A 17-year-old, G0 presents with a primary complaint of bright red vaginal bleeding and abdominal cramping of 6 hours duration. The patient reports feeling pregnant, but states her LNMP was 3+ months ago, and no pregnancy test was accomplished. PMH and surgical history are non-contributory. Which of the following is the LEAST likely diagnosis?
A 17-year-old, G0 presents with a primary complaint of bright red vaginal bleeding and abdominal cramping of 6 hours duration. The patient reports feeling pregnant, but states her LNMP was 3+ months ago, and no pregnancy test was accomplished. PMH and surgical history are non-contributory. Which of the following is the LEAST likely diagnosis?
What symptoms may indicate a spontaneous abortion?
What symptoms may indicate a spontaneous abortion?
A patient presents with bleeding and pain. What type of pregnancy can cause bleeding?
A patient presents with bleeding and pain. What type of pregnancy can cause bleeding?
Vaginal bleeding and abdominal pain can occur in which of the following non-viable pregnancy condition?
Vaginal bleeding and abdominal pain can occur in which of the following non-viable pregnancy condition?
The passing of a pregnancy at ________ weeks is considered a spontaneous abortion.
The passing of a pregnancy at ________ weeks is considered a spontaneous abortion.
What is a symptom of spontaneous abortion mentioned?
What is a symptom of spontaneous abortion mentioned?
What is considered an abnormality in pregnancies in reference to this presentation?
What is considered an abnormality in pregnancies in reference to this presentation?
Spontaneous abortion is defined as the passing of a pregnancy at less than _____ weeks gestation?
Spontaneous abortion is defined as the passing of a pregnancy at less than _____ weeks gestation?
A 17-year-old, G0 presents with a 6-hour history of bright red vaginal bleeding and abdominal cramping. She reports feeling pregnant, but has not taken a pregnancy test. The patient probably has which condition?
A 17-year-old, G0 presents with a 6-hour history of bright red vaginal bleeding and abdominal cramping. She reports feeling pregnant, but has not taken a pregnancy test. The patient probably has which condition?
Which symptom is LEAST associated with spontaneous abortion?
Which symptom is LEAST associated with spontaneous abortion?
Bright red vaginal bleeding and abdominal cramping are most indicative of _____.
Bright red vaginal bleeding and abdominal cramping are most indicative of _____.
The MOST common symptoms of early pregnancy abnormalities include vaginal __________ and abdominal __________.
The MOST common symptoms of early pregnancy abnormalities include vaginal __________ and abdominal __________.
In a non-viable intrauterine pregnancy, which of the following is UNLIKELY?
In a non-viable intrauterine pregnancy, which of the following is UNLIKELY?
Which condition may present with vaginal bleeding but is NOT an abortion?
Which condition may present with vaginal bleeding but is NOT an abortion?
Which type of bleeding in early pregnancy is generally considered benign?
Which type of bleeding in early pregnancy is generally considered benign?
Loss of pregnancy symptoms is suggestive of which condition?
Loss of pregnancy symptoms is suggestive of which condition?
Symptoms of abortion include vaginal bleeding and what other symptom?
Symptoms of abortion include vaginal bleeding and what other symptom?
Flashcards
Hydatidiform Mole
Hydatidiform Mole
Also known as a molar pregnancy, it's part of gestational trophoblastic disease (GTD) and occurs after abnormal fertilization.
Gestational Trophoblastic Disease (GTD)
Gestational Trophoblastic Disease (GTD)
A range of conditions that start in the placenta, marked by unusual growth of placental (trophoblastic) tissue.
Aberrant Fertilization (in Molar Pregnancy)
Aberrant Fertilization (in Molar Pregnancy)
Occurs when fertilization goes wrong, leading to the development of either a complete or partial molar pregnancy.
Complete Molar Pregnancy
Complete Molar Pregnancy
Signup and view all the flashcards
Partial Molar Pregnancy
Partial Molar Pregnancy
Signup and view all the flashcards
Choriocarcinoma
Choriocarcinoma
Signup and view all the flashcards
Choriocarcinoma Symptoms
Choriocarcinoma Symptoms
Signup and view all the flashcards
Ectopic Pregnancy
Ectopic Pregnancy
Signup and view all the flashcards
Symptoms of Ectopic Pregnancy
Symptoms of Ectopic Pregnancy
Signup and view all the flashcards
Ruptured Ectopic Pregnancy Symptoms
Ruptured Ectopic Pregnancy Symptoms
Signup and view all the flashcards
Hydatidiform Mole (Molar Pregnancy)
Hydatidiform Mole (Molar Pregnancy)
Signup and view all the flashcards
Invasive Mole
Invasive Mole
Signup and view all the flashcards
Complete Hydatidiform Mole
Complete Hydatidiform Mole
Signup and view all the flashcards
Partial Hydatidiform Mole
Partial Hydatidiform Mole
Signup and view all the flashcards
Diagnosis of Complete Mole
Diagnosis of Complete Mole
Signup and view all the flashcards
Treatment for Hydatidiform Mole
Treatment for Hydatidiform Mole
Signup and view all the flashcards
Spontaneous Abortion
Spontaneous Abortion
Signup and view all the flashcards
Vaginal Bleeding and Abdominal Pain
Vaginal Bleeding and Abdominal Pain
Signup and view all the flashcards
Symptoms Reported by Patient
Symptoms Reported by Patient
Signup and view all the flashcards
Signs and Symptoms of Abortion
Signs and Symptoms of Abortion
Signup and view all the flashcards
Sub-chorionic Hemorrhage
Sub-chorionic Hemorrhage
Signup and view all the flashcards
Obstetrics
Obstetrics
Signup and view all the flashcards
Objectives of Obstetrics Study
Objectives of Obstetrics Study
Signup and view all the flashcards
Key Obstetric Topics
Key Obstetric Topics
Signup and view all the flashcards
Early Pregnancy Abnormalities
Early Pregnancy Abnormalities
Signup and view all the flashcards
Non-Viable Pregnancy
Non-Viable Pregnancy
Signup and view all the flashcards
Viable Intra-Uterine Pregnancy
Viable Intra-Uterine Pregnancy
Signup and view all the flashcards
Molar Pregnancy
Molar Pregnancy
Signup and view all the flashcards
Physiologic Implantation Bleeding
Physiologic Implantation Bleeding
Signup and view all the flashcards
Patient Symptoms
Patient Symptoms
Signup and view all the flashcards
Preterm Labor
Preterm Labor
Signup and view all the flashcards
Risk Factors for Preterm Labor
Risk Factors for Preterm Labor
Signup and view all the flashcards
Preterm Labor Management (Pharmacological)
Preterm Labor Management (Pharmacological)
Signup and view all the flashcards
Preterm Labor: Non-Pharmacological Management
Preterm Labor: Non-Pharmacological Management
Signup and view all the flashcards
Neonatal Consequences of Preterm Delivery
Neonatal Consequences of Preterm Delivery
Signup and view all the flashcards
Respiratory Distress Syndrome (RDS)
Respiratory Distress Syndrome (RDS)
Signup and view all the flashcards
Respiratory Distress Syndrome (RDS) Treatment
Respiratory Distress Syndrome (RDS) Treatment
Signup and view all the flashcards
Tocolytics
Tocolytics
Signup and view all the flashcards
Hemolytic Disease of the Newborn (HDN)
Hemolytic Disease of the Newborn (HDN)
Signup and view all the flashcards
Complications of HDFN
Complications of HDFN
Signup and view all the flashcards
Phototherapy (for HDFN)
Phototherapy (for HDFN)
Signup and view all the flashcards
Anti-D Immune Globulin Mechanism
Anti-D Immune Globulin Mechanism
Signup and view all the flashcards
Anti-D Immune Globulin Timing
Anti-D Immune Globulin Timing
Signup and view all the flashcards
Premature Rupture of Membranes (PROM)
Premature Rupture of Membranes (PROM)
Signup and view all the flashcards
Preterm Premature Rupture of Membranes (PPROM)
Preterm Premature Rupture of Membranes (PPROM)
Signup and view all the flashcards
PROM/PPROM Diagnosis
PROM/PPROM Diagnosis
Signup and view all the flashcards
PROM/PPROM Complications
PROM/PPROM Complications
Signup and view all the flashcards
PROM/PPROM Management
PROM/PPROM Management
Signup and view all the flashcards
Ectopic Pregnancy Risk Factors
Ectopic Pregnancy Risk Factors
Signup and view all the flashcards
Ectopic Pregnancy Treatment
Ectopic Pregnancy Treatment
Signup and view all the flashcards
Postpartum Hemorrhage
Postpartum Hemorrhage
Signup and view all the flashcards
4 Ts of Postpartum Hemorrhage
4 Ts of Postpartum Hemorrhage
Signup and view all the flashcards
Causes of Postpartum Hemorrhage
Causes of Postpartum Hemorrhage
Signup and view all the flashcards
Immediate Management of PPH
Immediate Management of PPH
Signup and view all the flashcards
Chief Complaint Case
Chief Complaint Case
Signup and view all the flashcards
Postpartum Hemorrhage Risk Factors
Postpartum Hemorrhage Risk Factors
Signup and view all the flashcards
Trauma Causes of Postpartum Hemorrhage
Trauma Causes of Postpartum Hemorrhage
Signup and view all the flashcards
Discriminatory Zone (hCG)
Discriminatory Zone (hCG)
Signup and view all the flashcards
Purpose of Discriminatory Zone
Purpose of Discriminatory Zone
Signup and view all the flashcards
Ectopic Pregnancy Diagnosis
Ectopic Pregnancy Diagnosis
Signup and view all the flashcards
Alloimmunization in Pregnancy
Alloimmunization in Pregnancy
Signup and view all the flashcards
Rh Genetics
Rh Genetics
Signup and view all the flashcards
Alloimmunization Process
Alloimmunization Process
Signup and view all the flashcards
Causes of Alloimmunization
Causes of Alloimmunization
Signup and view all the flashcards
Immune Hydrops Fetalis
Immune Hydrops Fetalis
Signup and view all the flashcards
Management of Rh alloimmunization
Management of Rh alloimmunization
Signup and view all the flashcards
PUBS
PUBS
Signup and view all the flashcards
Placenta Previa
Placenta Previa
Signup and view all the flashcards
Diagnosis of Placental Previa
Diagnosis of Placental Previa
Signup and view all the flashcards
Management of Placenta Previa
Management of Placenta Previa
Signup and view all the flashcards
Bleeding & Pain in Early Pregnancy
Bleeding & Pain in Early Pregnancy
Signup and view all the flashcards
Abortion Symptoms
Abortion Symptoms
Signup and view all the flashcards
Implantation Bleeding
Implantation Bleeding
Signup and view all the flashcards
ED (in OB context)
ED (in OB context)
Signup and view all the flashcards
LNMP
LNMP
Signup and view all the flashcards
Spontaneous Abortion Definition
Spontaneous Abortion Definition
Signup and view all the flashcards
Non-Viable Intra-Uterine Pregnancy
Non-Viable Intra-Uterine Pregnancy
Signup and view all the flashcards
G0
G0
Signup and view all the flashcards
Typical Abortion Symptoms
Typical Abortion Symptoms
Signup and view all the flashcards
Passage of Tissue/Fluid
Passage of Tissue/Fluid
Signup and view all the flashcards
Loss of Pregnancy Symptoms
Loss of Pregnancy Symptoms
Signup and view all the flashcards
Back Pain in Abortion
Back Pain in Abortion
Signup and view all the flashcards
Initial Assessment Steps
Initial Assessment Steps
Signup and view all the flashcards
Study Notes
- G0, 17-year-old presents to the ED with a 6 hour history of bright red vaginal bleeding and abdominal cramping
- Reports feeling pregnant without taking a pregnancy test.
- Last menstrual period 3+ months ago.
- PMH and surgical history are non-contributory.
Types of Abortions
- Threatened abortion involves bleeding before the 20th completed week in a viable gestation
- Complete abortion implies that expulsion of all conception products happened before 20 weeks.
- Incomplete abortion is the incomplete expulsion of conception products before 20 weeks.
- Inevitable abortion means the cervix is dilated with bleeding before 20 weeks of gestation.
- Missed abortion refers to a nonviable gestational sac retained without dilation.
Signs and Symptoms of Abortion
- Include vaginal bleeding, cramping and pain, passage of tissue or fluid and back pain.
- Other symptoms are loss of pregnancy symptoms
Etiologies of Abortion
- Genetric factors
- Advanced Maternal Age
- Chronic Health Conditions
- Infections
- Uterine Abnormalities
- Exposure to Toxins
Etiologies of Abortion - Genetic Factors
- Aneuploidy accounts for greater than 50% of early pregnancy losses.
- Autosomal trisomies are the most commone.
- Trisomy 16 is very common
- Monosomy X (45 X) is very common
Diagnosis of Abortion
- Transvaginal ultrasonography.
- Quantitative beta-hCG testing.
- A pelvic examination
- Type and screen for blood type.
- Examination of passed tissue
Management of Abortion
- Suction curettage
Recurrent Abortion
- Defined as two or more failed pregnancies before '20 weeks gestation'
- Related to
- Genetic Factors
- Uterine Abnormalities
- Hormonal Factors
- Immune Disorders
Gestational Trophoblastic Disease (GTD) Symptoms
- Abnormal uterine bleeding is the most common presenting symptom.
- The uterus may be larger than expected for gestational age.
- Nausea and vomiting may require hospitalization.
- Preeclampsia can show during the first or early second trimester
- Passage of "grape-like" structures from the vagina.
GTD - Pregnancy
- 32-year-old G2P1 at 8 weeks presents with severe nausea and vomiting requiring IV hydration
- Intermittent vaginal bleeding for 3 days with grape-like structures in blood
- The patient presents with a snowfall pattern on transvaginal ultrasound.
Normal Fertilization
- The female pronucleus and male pronucleus both have 23 chromosomes.
- After combining there are 46 total.
Types of Abnormal trophoblast proliferation
Benign:
- Gestational Trophoblastic Disease (GTD)
- Hydatidiform Moles
- Complete Mole & Partial Mole Malignant: Gestational Trophoblastic Neoplasia (GTN)
- Invasive Moles, Choriocarcinoma, Placental Site, Trophoblastic Tumor.
Alloimmunization in Pregnancy
- Is marked by transplacental maternal antibodies that destroy fetal erythrocytes
- Overproduction of immature RBCs marks fetal and neonatal RBCs
- Can lead to Hemolytic disease of the fetus and newborn (HDFN)
- CcDEe are main antigens of Rh blood group
- D is very important Rh antigen
Rh Genetics
- Antigen D was discovered in Rhesus monkeys in 1940
- Presence of antigen D = Rhesus positive (Rh+)
- 65% of Rh+ men are heterozygous (Dd) and 35% are homozygous (dd)
- The D gene is dominant, DD and Dd are Rh+, and dd is Rh-
Alloimmunization Process
- Maternal Rh antibodies are IgG, acquired through exposure to Rh+ blood
- First pregnancy not usually affected
- In subsequent pregnancies, the mother will already possess IgG antibodies to the Rh factor
- Fetal hydrops or hemolytic disease of the newborn.
Risk conditions for Alloimmunization
- Includes third stage of labor, Cesarean section, antepartum and postpartum hemorrhage, abortion/ectopic pregnancy, amniocentesis and chorionic villus sampling, and abdominal trauma.
Result of all immunization - Immune Hydrops Fetalis
- Leads to Hemolytic disease
- Causes destruction of fetal red blood cells
- Hemolytic anemia causes
- Tissue hypoxia
- Leads to Metabolic acidosis
- Generalized edema, ascites, Pleural effusions
- Can cause Fetal death secondary to cardiac failure
Management of Rh alloimmunization
- Liley Curve
- Middle cerebral artery doppler
- Percutaneous Umbilical Blood Sampling (PUBS)
Result of Severe RH alloimmunization - Hemolytic Disease of the Fetus and Newborn (HDN)
- Can cause Jaundice and kernicterus.
Complications of Hemolytic Disease of the Fetus and Newborn (HDN)
- Causes Anemia, Cardiac complications
- Leads to Hyperbilirubinemia, jaundice, kernicterus
- Can result in Kernicterus Spectrum Disorder
- Causes Cerebral Palsy
- Causes Hearing Loss
- Causes Vision Problems
- Causes Cognitive and learning issues
Treatment of Hemolytic Disease of the Fetus and Newborn
- Phototheraphy
Treatment of Rh Disease
- Anti-D Immune Globulin, which is derived from individuals with high-titer immunoglobuline D antibodies
- Given Prophylatically to all D-negative, unsensitized women at 28 weeks and after delivery if newborn is D-positive
- Given as Standard IM dose of anti-D immune globulin-300 µg or 1500 IU
Premature Rupture of Membranes
- 35 yo G₁Po, at 36 weeks, presents with leaking clear fluid.
- Is diagnosed from Nitrazine test, Fern test, Immunoassay (Amnisure) and Ultrasound.
- PROM, ≥ 37 gestation when membranes rupture prior to onset of labor
- PPROM, membranes rupture prior to onset of labor before < 37 gestation.
PREMATURE RUPTURE OF MEMBRANES (PROM)
- Risk factors include Infection Polyhydramnios and Smoking/drugs
- Complications can be Infection/*endometritis, Placental abruption, Umbilical cord prolapse, leading to Respiratory distress of newborn and can cause Skeletal deformities
- Management includes treatments for Group B Streptococcus, Corticosteroids and to Montior.
Preterm Labor
- 17-year-old G₁ at 34 weeks gestation presents with c/o lower abdominal cramping and lower back pain
- Report feelings of 3-5 contractions per hour and denies vaginal bleeding or rupture of membranes.
- Cervix is 1 cm and 60% effaced.
Preterm Labor Indicators
- The is when Gestational age is > 20 0/7 weeks and < 37 0/7 weeks
- This causes Regular uterine contractions at frequent intervals and documented cervical dilatation or effacement
Risk conditions for preterm Labor
- History of Preterm birth
- Short inter pregnancy interval
- Vaginal Bleeding and Urinary Tract Infections
- Cervical Surgery
- Low Maternal BMI
- Related to smoking and alcohol
- Short Cervical Length
Preterm birth per race, 2021-2023
- Black accounts for 14.7% of all preterm births
- American Indian accounts for 12.1%
- Hispanic accounts for 10.2%
- White accounts for 9.8%
- Asian accounts for 9.2%
Preterm Labor Management
- Calcium channel blockers
- Beta-adrenergic receptor agonists
- NSAID
- Magnesium Sulfate
- Bedrest
- Also treat with Corticosteroids to accelerate fetal lung maturity (between 23 and 34 weeks)
- Betamethasone, 12mg IM q24hours for total of 2 doses
- Dexamthasone, 6 mg IM, q12 hours apart for total of 4 doses
Neonatal Consequences of preterm Delivery
- Causes Respiratory distress
- Infections
- Intraventricular hemorrhage
- Causes Retinopathy of prematurity
Respiratory Distress Syndrome can result from
- Hyaline membrane disease
- Caused by a lack of surfactant in the lungs
- Treated with Surfactant replacement therapy and Continuous positive airway pressure (CPAP)
Spontaneous Abortion
- Occurs prior to 20 weeks gestation
- 15-20%
- 80% in 1st 12 weeks
Risk factors of spontaneous abortion
- parity
- increasing maternal/paternal age
- smoking
S/S: of spontaneous abortion:
- crampy, Abd pain, fever, pain, bleeding if septic
Threatened abortion
- vaginal bleeding WITHOUT cervical dilation or passage of tissues -50%
inevitable abortion:
- ruptures, cervical diliataion: Painful contractions
incomplete abortion:
- tissue is passed, retained material
- curettage used to remove conceptions
Complete abortion:
-tissue passed, cervix closed
missed abortion:
- no/failed heart beat, closed cervix
- Sxs persistent amenorrhea
Labs spontaneous abortions:
- high titers, viable pregnancy.
- blood type
Elective Abortion:
-termined
- No risk of complications.
Ectopic pregnancy diagnosis
- physical exam, HCG, ultrasound
Partial/low-lying
- resolve in 32-35 weeks
Sxs : placenta
-Pain less, resolves.
- Avoid digital exam
A abruptio placenta sxs :
- trauma, chronic HTN and smoking. Painful /con, tender.
- Labs: CBC, fibrin blood type -US evaluation
Management :
-delivery
- Cautions of bleeding
heterotopic : is
- extrauterine
Hemolytic
- RHD IM
- autoantibodies
Kernicterus
- 37 weeks
- heel prick
- UV. Exchange
Gestational Trophoblastic Disease (GTD)
-
aka) a molar pregnancy
-
Part of the spectrum of interrelated conditions classified as gestational trophoblastic disease Occurs after aberrant fertilization
-
There's two forms: 1) complete molar pregnancy 2) Partial molar pregnancy
What is it?
-
Spectrum of interrelated conditions originating in the placenta w/ abnormal placental (trophoblastic) proliferation. Types of GTD:
-
Hydatidiform mole (molar pregnancy)- MC presentation usually benign Intrusive -invasive in the uterus Choriocarcinoma malignant transformation
Complete mole
fetal tissue, fertilization of egg w/ no DNA (cells that were meant to become the placenta are abnormal) fetal tissue plus molar degeneration fertilization of normal egg w/ 2 sperm (part of fetus forms cells vaginal size absent hyperthyroidism seen trimes (tachy warm )
Complete Mole:
Ultrason is "snowstorm”, “cluster of grapes”, “Swiss cheese” appearance b/c of absence fetus
Partial Mole:
difficult to do (fetus may be present but growth restricted)
Both:
amniotic fluid
- Abnorm placenta diameter elev
-S/S of ectopic pregnancy:
- Amenorrhea, vaginal bleeding, abdominal pain, cervical motion tenderness (and 1/3 of women have adnexal mass on exam)
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.