Hydatidiform Mole: Diagnosis and Treatment
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Questions and Answers

How is Epithelioid Trophoblastic Tumor diagnosed?

  • Neurological examination
  • Histopathological examination of uterine tissue (correct)
  • X-ray of the foot
  • Blood test for cholesterol levels

    • What is a common symptom of Epithelioid Trophoblastic Tumor?

  • Vaginal bleeding (correct)
  • Nosebleeds
  • Joint pain
  • Coughing

    • What is a potential complication of a Molar Pregnancy?

  • Hair loss
  • Shoulder pain
  • Preeclampsia (correct)
  • Toothache

    • What is a common treatment for Placental Site Trophoblastic Tumor?

    <p>Surgical removal (hysterectomy or tumor resection)</p> Signup and view all the answers

    Where does Epithelioid Trophoblastic Tumor typically develop?

    <p>Uterus or cervix</p> Signup and view all the answers

    How can the risk of malignant transformation in a Molar Pregnancy be reduced?

    <p>Regular beta-hCG level monitoring</p> Signup and view all the answers

    What is a characteristic that distinguishes a complete mole from a partial mole?

    <p>Presence of fetal tissue</p> Signup and view all the answers

    Which of the following is a common complication of molar pregnancy?

    <p>Thyroid dysfunction</p> Signup and view all the answers

    What is the primary treatment for choriocarcinoma?

    <p>Chemotherapy</p> Signup and view all the answers

    Which of the following is a characteristic of placental site trophoblastic tumor?

    <p>Typically develops at the implantation site of the placenta</p> Signup and view all the answers

    What is the primary method of diagnosis for hydatidiform mole?

    <p>Ultrasound</p> Signup and view all the answers

    Which of the following is a potential risk factor for developing gestational trophoblastic disease?

    <p>All of the above</p> Signup and view all the answers

    Study Notes

    Hydatidiform Mole

    • Definition: A type of gestational trophoblastic disease where the placenta grows abnormally and forms a mass of cysts
    • Types:
      • Complete mole: Only paternal chromosomes present, no fetal tissue
      • Partial mole: Both paternal and maternal chromosomes present, some fetal tissue
    • Symptoms:
      • Vaginal bleeding
      • Abdominal pain
      • Enlarged uterus
    • Diagnosis:
      • Ultrasound
      • Serum beta-hCG levels
      • Histopathological examination of uterine tissue
    • Treatment:
      • Suction evacuation of the uterus
      • Follow-up with serial beta-hCG levels to monitor for malignant transformation

    Choriocarcinoma

    • Definition: A malignant type of gestational trophoblastic disease that originates from the placenta
    • Characteristics:
      • Highly aggressive and invasive
      • Can metastasize to lungs, brain, and other organs
    • Symptoms:
      • Vaginal bleeding
      • Abdominal pain
      • Shortness of breath (if lung metastases)
    • Diagnosis:
      • Histopathological examination of uterine tissue
      • Serum beta-hCG levels
      • Imaging studies (e.g. CT, MRI)
    • Treatment:
      • Chemotherapy (methotrexate, actinomycin D, etc.)
      • Surgery (in some cases)

    Placental Site Trophoblastic Tumor

    • Definition: A rare type of gestational trophoblastic disease that originates from the placenta
    • Characteristics:
      • Typically develops at the implantation site of the placenta
      • Can be benign or malignant
    • Symptoms:
      • Vaginal bleeding
      • Abdominal pain
      • Enlarged uterus
    • Diagnosis:
      • Histopathological examination of uterine tissue
      • Serum beta-hCG levels
      • Imaging studies (e.g. CT, MRI)
    • Treatment:
      • Hysterectomy (in most cases)
      • Chemotherapy (in some cases)

    Epithelioid Trophoblastic Tumor

    • Definition: A rare type of gestational trophoblastic disease that originates from the placenta
    • Characteristics:
      • Typically develops in the uterus or cervix
      • Can be benign or malignant
    • Symptoms:
      • Vaginal bleeding
      • Abdominal pain
      • Enlarged uterus
    • Diagnosis:
      • Histopathological examination of uterine tissue
      • Serum beta-hCG levels
      • Imaging studies (e.g. CT, MRI)
    • Treatment:
      • Surgery (hysterectomy or tumor resection)
      • Chemotherapy (in some cases)

    Molar Pregnancy Complications

    • Risk of malignant transformation:
      • Complete mole: 15-20%
      • Partial mole: 0.5-1%
    • Other complications:
      • Recurrent molar pregnancy
      • Thyrotoxicosis
      • Preeclampsia
      • Post-molar pregnancy syndrome (rare)
    • Follow-up care:
      • Regular beta-hCG level monitoring
      • Imaging studies (e.g. ultrasound, CT)
      • Contraception to prevent pregnancy until beta-hCG levels return to normal

    Gestational Trophoblastic Diseases

    Hydatidiform Mole

    • A type of gestational trophoblastic disease characterized by abnormal placental growth and formation of cysts
    • Two types: complete mole (only paternal chromosomes present, no fetal tissue) and partial mole (both paternal and maternal chromosomes present, some fetal tissue)
    • Symptoms: vaginal bleeding, abdominal pain, and enlarged uterus
    • Diagnosis: ultrasound, serum beta-hCG levels, and histopathological examination of uterine tissue
    • Treatment: suction evacuation of the uterus and follow-up with serial beta-hCG levels to monitor for malignant transformation

    Choriocarcinoma

    • A malignant type of gestational trophoblastic disease originating from the placenta
    • Characteristics: highly aggressive and invasive, can metastasize to lungs, brain, and other organs
    • Symptoms: vaginal bleeding, abdominal pain, and shortness of breath (if lung metastases)
    • Diagnosis: histopathological examination of uterine tissue, serum beta-hCG levels, and imaging studies (e.g. CT, MRI)
    • Treatment: chemotherapy (methotrexate, actinomycin D, etc.) and surgery (in some cases)

    Placental Site Trophoblastic Tumor

    • A rare type of gestational trophoblastic disease originating from the placenta
    • Typically develops at the implantation site of the placenta and can be benign or malignant
    • Symptoms: vaginal bleeding, abdominal pain, and enlarged uterus
    • Diagnosis: histopathological examination of uterine tissue, serum beta-hCG levels, and imaging studies (e.g. CT, MRI)
    • Treatment: hysterectomy (in most cases) and chemotherapy (in some cases)

    Epithelioid Trophoblastic Tumor

    • A rare type of gestational trophoblastic disease originating from the placenta
    • Typically develops in the uterus or cervix and can be benign or malignant
    • Symptoms: vaginal bleeding, abdominal pain, and enlarged uterus
    • Diagnosis: histopathological examination of uterine tissue, serum beta-hCG levels, and imaging studies (e.g. CT, MRI)
    • Treatment: surgery (hysterectomy or tumor resection) and chemotherapy (in some cases)

    Molar Pregnancy Complications

    • Risk of malignant transformation: 15-20% for complete mole and 0.5-1% for partial mole
    • Other complications: recurrent molar pregnancy, thyrotoxicosis, preeclampsia, and post-molar pregnancy syndrome (rare)
    • Follow-up care: regular beta-hCG level monitoring, imaging studies (e.g. ultrasound, CT), and contraception to prevent pregnancy until beta-hCG levels return to normal

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    Description

    A quiz about Hydatidiform mole, a type of gestational trophoblastic disease, its types, symptoms, diagnosis, and treatment options.

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