Nutritional Biochemistry Overview 2022-2023
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Nutritional Biochemistry Overview 2022-2023

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Questions and Answers

What is Nutrition?

Composition and quantity of food intake by living organisms

Which of the following are areas of human nutrition?

  • Malnutrition only
  • Optimal nutrition (correct)
  • Undernutrition (correct)
  • Overnutrition (correct)
  • Malnutrition in humans is assessed by dietary intake studies, biochemical studies, and __________

    clinical symptoms

    What are Dietary Reference Intakes (DRIs)?

    <p>Quantitative estimates of nutrient intakes required to prevent deficiencies and maintain optimal health in populations</p> Signup and view all the answers

    What are the four standards of Dietary Reference Intakes (DRIs)?

    <p>Estimated Average Requirement (EAR)</p> Signup and view all the answers

    What does the Recommended Dietary Allowance (RDA) represent?

    <p>The amount of nutrient intake that is sufficient to meet the nutritional requirement of nearly all healthy individuals in a group</p> Signup and view all the answers

    Humans can synthesize their own vitamin C.

    <p>False</p> Signup and view all the answers

    What is the function of Vitamin C in metabolic processes?

    <p>Functions as a cofactor, enzyme complement, co-substrate, and a powerful anti-oxidant</p> Signup and view all the answers

    What historical problem was associated with the lack of Vitamin C?

    <p>Scurvy</p> Signup and view all the answers

    List two food sources high in Vitamin C.

    <p>Oranges and strawberries</p> Signup and view all the answers

    Vitamin C is known as __________.

    <p>ascorbic acid</p> Signup and view all the answers

    Study Notes

    Nutrition Overview

    • Nutrition encompasses the composition and quantity of food intake by living organisms, along with biochemical utilization.
    • Human nutrition is categorized into three areas:
      • Undernutrition (nutrient deficiency)
      • Overnutrition (excessive nutrient intake)
      • Optimal nutrition (balanced nutrient intake)

    Assessment of Malnutrition

    • Malnutrition is assessed through:
      • Dietary intake studies to identify individuals with deficient diets.
      • Biochemical studies identifying subclinical nutritional deficiencies.
      • Clinical symptoms revealing clinical nutritional deficiencies.

    Dietary Reference Intakes (DRIs)

    • DRIs provide quantitative estimates of nutrient intake needed to prevent deficiencies and maintain optimal health in populations.
    • DRIs are recommended by the Food and Nutrition Board of the National Research Council, USA.

    Four Standards of DRIs

    • Estimated Average Requirement (EAR): Nutrient intake to meet requirements of 50% of healthy individuals in a specific group.
    • Recommended Dietary Allowance (RDA): Intake sufficient for 97-98% of healthy individuals; calculated as RDA = EAR + 2 SD.
    • Adequate Intake (AI): Used when EAR/RDA cannot be established; approximates the nutrient needs for all individuals in a group.
    • Tolerable Upper Intake Level (UL): Highest daily intake with no adverse health effects or toxicity for almost all individuals.

    Vitamin C (Ascorbic Acid)

    • Vitamin C functions as a cofactor in enzyme reactions, a powerful antioxidant, and stabilizes vitamins E and folic acid while enhancing iron absorption.
    • It neutralizes free radicals and inflammatory responses, including sepsis.
    • Vitamin C cannot be synthesized by humans; it must be obtained through diet.

    Chemical Properties and Metabolism of Vitamin C

    • During oxidation of ascorbic acid, an ascorbyl radical forms but reacts poorly with oxygen, preventing harmful reactive oxygen species formation.
    • Dehydroascorbic acid can revert to ascorbic acid with help from reduced glutathione.
    • Vitamin C has several vitamers active in animals, including different forms dependent on pH.

    Historical Context of Vitamin C

    • Scurvy, a disease due to vitamin C deficiency, was prevalent among sailors; refusal to consume fresh fruits led to high mortality.
    • The remedy of consuming lime juice reduced scurvy's effects, leading to British sailors being nicknamed "limey."
    • Humans cannot synthesize vitamin C due to the absence of gulonolactone oxidase, the final enzyme in its synthesis pathway.

    Food Sources of Vitamin C

    • Rich sources include fruits, vegetables, and organ meats; notable examples are:
      • Asparagus, papaya, oranges, cantaloupe, cauliflower, broccoli, green peppers, grapefruit, lemons, strawberries.
    • Citrus products are highlighted as significant vitamin C sources.
    • Supplements typically provide vitamin C as free ascorbic acid, calcium ascorbate, sodium ascorbate, and related forms.

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    Description

    This quiz focuses on the fundamentals of Nutritional Biochemistry, including the composition and quantity of food intake by living organisms. It covers the three main areas of human nutrition: undernutrition, overnutrition, and optimal nutrition, along with methods of assessing malnutrition.

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