Nutrition and Obesity Quiz

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Questions and Answers

What is the threshold for classifying an individual as obese based on BMI?

  • BMI > 30 (correct)
  • BMI > 35
  • BMI > 25
  • BMI > 27

Which of the following is a serious disorder highly related to obesity?

  • Alzheimer's disease
  • Asthma
  • Diabetes mellitus (correct)
  • Influenza

What demographic trend has been observed regarding obesity prevalence in lower socio-economic groups?

  • Higher prevalence in lower socio-economic groups (correct)
  • No significant change with economic status
  • Lower incidence in lower socio-economic groups
  • Higher prevalence in upper socio-economic groups

In which regions is the prevalence of obesity accelerating markedly?

<p>Less developed countries like Asia and urban Africa (A)</p> Signup and view all the answers

What is a limitation of using BMI as a metric for obesity?

<p>It does not consider differences in muscle mass versus body fat. (B)</p> Signup and view all the answers

What serious condition is NOT listed as a consequence of obesity?

<p>Osteoporosis (D)</p> Signup and view all the answers

Which vitamin's supplementation successfully ended an epidemic of rickets?

<p>Vitamin D (B)</p> Signup and view all the answers

Which accessory organ is primarily responsible for the initial breakdown of starch?

<p>Salivary glands (B)</p> Signup and view all the answers

What is the primary function of the vagus nerve in relation to the gastrointestinal tract?

<p>Links most digestive organs and alters metabolic responses (B)</p> Signup and view all the answers

Which of the following nutrients is associated with the prevention of pernicious anemia?

<p>Vitamin B12 (B)</p> Signup and view all the answers

What condition resulted from thiamine deficiency, often linked to polished rice consumption?

<p>Beriberi (C)</p> Signup and view all the answers

Which food-related disease is NOT mentioned as a consequence of obesity?

<p>Celiac disease (D)</p> Signup and view all the answers

Which statement about sensory receptors in the GI tract is true?

<p>They are similar to taste receptors and activate the same pathways. (C)</p> Signup and view all the answers

What is the primary effect of extendin-4 in animals?

<p>Raises blood insulin and lowers blood glucose (A)</p> Signup and view all the answers

How does extendin-4 differ from GLP-1 in terms of stability?

<p>Extendin-4 is resistant to the enzyme that breaks down GLP-1 (A)</p> Signup and view all the answers

What is one clinical outcome improved by GLP-1 treatments?

<p>Reduced cardiovascular risk scores (C)</p> Signup and view all the answers

What happens when food enters the distal small intestine?

<p>Satiety signals are triggered, leading to reduced food intake (C)</p> Signup and view all the answers

Which factor is known to worsen triglyceride levels in relation to dietary carbohydrates?

<p>Excessive fructose consumption (D)</p> Signup and view all the answers

Which of the following factors makes individuals more sensitive to dietary carbohydrate effects?

<p>Obesity and insulin resistance (D)</p> Signup and view all the answers

What is the significance of the Gila monster's saliva in medical research?

<p>It led to the development of the first GLP-1 drug (B)</p> Signup and view all the answers

What is the 'intestinal brake' concept associated with GLP-1?

<p>Enhances nutrient storage and promotes satiety (C)</p> Signup and view all the answers

What type of protein deficiency is characterized solely by a lack of protein?

<p>Kwashiorkor (D)</p> Signup and view all the answers

Which of the following best describes the Acceptable Macronutrient Distribution Range (AMDR) for protein in adults?

<p>10 to 35% of energy (B)</p> Signup and view all the answers

How much protein is generally recommended per kilogram of body weight for adults?

<p>0.8 g/kg (B)</p> Signup and view all the answers

What is considered to be a high-quality protein according to the Digestible Indispensable Amino Acid Score (DIAAS)?

<p>100 or more (B)</p> Signup and view all the answers

What happens to excess protein beyond the optimal synthesis threshold?

<p>It is oxidized (D)</p> Signup and view all the answers

Which combination of foods can provide a complete protein in a vegan diet?

<p>Rice and Beans (C)</p> Signup and view all the answers

Which condition involves both energy and protein deficiency?

<p>Marasmus (A)</p> Signup and view all the answers

What effect does regular aerobic exercise have on protein requirements for athletes?

<p>Increases the oxidation of essential amino acids (B)</p> Signup and view all the answers

What does glycemic load measure?

<p>The food's glycemic index multiplied by the amount consumed (A)</p> Signup and view all the answers

Which of the following food items has a very low glycemic index?

<p>Lentils (C)</p> Signup and view all the answers

What is a primary cause of insulin resistance in skeletal muscle?

<p>Higher insulin secretion required for glucose transport (A)</p> Signup and view all the answers

Which diabetes type is characterized by the absence of insulin production?

<p>Type 1 diabetes (A)</p> Signup and view all the answers

What effect does a hypocaloric diet have on the metabolic rate?

<p>Reduces metabolic rate (B)</p> Signup and view all the answers

What is the metabolic fate of carbohydrates when consumed in excess?

<p>Oxidation or glycogen storage primarily (D)</p> Signup and view all the answers

What is the primary source of dietary protein for about two-thirds of the population in the U.S.?

<p>Meat, poultry, seafood, eggs, and dairy (A)</p> Signup and view all the answers

How do whole grains affect heart disease risk?

<p>Reduce the risk by lowering dietary cholesterol absorption (B)</p> Signup and view all the answers

What is true about essential amino acids?

<p>They must be obtained through diet (C)</p> Signup and view all the answers

Which of the following is an example of insulin resistance affecting the liver?

<p>Elevated blood glucose levels due to overproduction of glucose (A)</p> Signup and view all the answers

Which macronutrient has the greatest thermogenic effect based on the calorie composition?

<p>Proteins (B)</p> Signup and view all the answers

What leads to the poor glucose control indicated by high HbA1C levels?

<p>High glycosylation of hemoglobin due to elevated blood glucose (A)</p> Signup and view all the answers

What is the effect of a high-carbohydrate, low-fat diet on weight loss?

<p>Leads to weight loss when exercised and followed properly (C)</p> Signup and view all the answers

What is the main function of Cholecystokinin in digestion?

<p>It stimulates the release of digestive enzymes. (D)</p> Signup and view all the answers

Which type of carbohydrate consists of only one sugar unit?

<p>Monosaccharides (A)</p> Signup and view all the answers

How does pepsinogen become an active digestive enzyme?

<p>It is mixed with HCl. (A)</p> Signup and view all the answers

Which statement about fiber is correct?

<p>Fiber adds bulk to stools and supports digestive health. (A)</p> Signup and view all the answers

What effect does salivary amylase have on carbohydrates?

<p>It breaks starch into shorter polysaccharides. (D)</p> Signup and view all the answers

Which of the following is NOT a source of glucose?

<p>Fatty acids from triglycerides (B)</p> Signup and view all the answers

What type of carbohydrate is lactose?

<p>Disaccharide (D)</p> Signup and view all the answers

Which of the following hormones increases hunger when the body has not eaten?

<p>Ghrelin (B)</p> Signup and view all the answers

What is the primary role of pancreatic amylase in digestion?

<p>To break starch into monosaccharides. (B)</p> Signup and view all the answers

What indicates a food's glycemic index of 70?

<p>It causes a 70% blood glucose response compared to pure glucose. (A)</p> Signup and view all the answers

Which nutrient is absorbed most easily in the stomach?

<p>Alcohol (A)</p> Signup and view all the answers

In the context of dietary carbohydrates, which statement is true?

<p>Whole food carbohydrates provide a variety of essential nutrients. (C)</p> Signup and view all the answers

What is the primary ingredient that leads to lactose intolerance?

<p>Lactose, a disaccharide found in milk (D)</p> Signup and view all the answers

What process is responsible for linking two sugar molecules together?

<p>Dehydration reaction (D)</p> Signup and view all the answers

Flashcards

Obesity

A condition where a person has significantly more body fat than lean tissue, leading to various health problems.

Body Mass Index (BMI)

A weight-based measure used to assess obesity, calculated by dividing the body weight in kilograms by the square of the height in meters.

BMI Thresholds for Obesity

A BMI value greater than 30 indicates obesity, while a value between 27 and 30 suggests overweight.

Limitations of BMI

While BMI is a convenient indicator, it's not perfect for determining obesity. It doesn't account for muscle mass or body composition.

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Obesity and Socioeconomic Status

In developed nations, obesity prevalence is higher in lower socioeconomic groups, unlike historical patterns.

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What is the lumen of the digestive tract?

The lumen is the inner space of the gastrointestinal tract, from the mouth to the rectum. It faces the outside of the body, not the internal environment.

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What are accessory organs in the digestive system?

Accessory organs like the salivary glands, liver, pancreas, and gallbladder support digestion but are not part of the main GI tract.

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What are the roles of salivary glands?

Salivary glands produce saliva, lubricating food and initiating starch breakdown. Parotid glands produce watery saliva, and submaxillary/mandibular glands produce a mix of watery and mucus.

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What is a key role of the GI tract beyond digestion?

The GI tract protects the body from infections and toxins by its lining and immune responses.

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How does the GI tract affect the body beyond digestion?

The GI tract influences peripheral metabolism (how energy is managed) and feeding behavior, partly through the vagus nerve.

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How is taste connected to the GI tract?

Sensory receptors in the GI tract are similar to taste receptors and activate the same neural pathways, influencing our perception of food.

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What are the main digestive organs?

The esophagus, stomach, small intestine, colon (large intestine) are the key digestive organs.

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What are the main nerves controlling GI functions?

The vagus nerve connects many digestive organs with the brain, including the stomach, small intestine, liver, gallbladder, pancreas, and parts of the colon. The pelvic nerve controls the rectum and bladder.

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Cholecystokinin (CCK)

A hormone that stimulates the release of digestive enzymes from the pancreas and gallbladder, promoting feelings of fullness after eating.

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Incretins (GLP-1 & GIP)

Hormones secreted by the gut that regulate insulin secretion in response to food intake.

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Peptide YY (PYY)

A hormone secreted by the gut that signals satiety (fullness) and reduces appetite.

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Neuropeptide Y (NPY)

A neurotransmitter acting in the brain that stimulates appetite, particularly for carbohydrates.

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Ghrelin

A hormone produced by the stomach that stimulates appetite, especially for fatty foods.

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Substance P

A neurotransmitter involved in pain perception and inflammation, also implicated in the digestive system.

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Gastrointestinal Motility

The process of moving food along the digestive tract, involving both propulsion and mixing.

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Peristalsis

The rhythmic, wave-like contractions of smooth muscle that propel food through the digestive tract.

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Digestion

The process of breaking down food into smaller components through mechanical and chemical actions.

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Pepsinogen

Inactive precursor of pepsin, an enzyme that breaks down proteins in the stomach.

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Glucose

The primary fuel source for the brain and central nervous system.

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Gluconeogenesis

The process of converting non-carbohydrate sources (like proteins) into glucose.

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Glycogen

A complex carbohydrate found in animals, primarily stored in the liver and muscles.

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Starches

Complex carbohydrates found in plants and other organisms, providing energy and fiber.

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Fiber

Non-digestible plant material that adds bulk to stools and promotes digestive health.

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Carb Digestion

The process of breaking down starch and other carbohydrates into smaller sugars for absorption.

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What are enzymes?

Enzymes are biological catalysts that accelerate chemical reactions within cells, facilitating metabolism and vital functions.

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What do transport proteins do?

Transport proteins act like gatekeepers, moving substances across cell membranes, regulating the internal environment and enabling essential processes.

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What are antibodies?

Antibodies are specialized proteins produced by the immune system that recognize and neutralize foreign invaders, such as bacteria and viruses, protecting against infections.

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What are contractile proteins?

Contractile proteins, like actin and myosin, are the building blocks of muscles, allowing for movement by contracting and relaxing, enabling locomotion and other bodily functions.

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What are hormones?

Hormones are chemical messengers produced by glands, like insulin and glucagon, that travel through the bloodstream to target cells, regulating various processes, such as metabolism and growth.

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How do proteins regulate fluids and pH?

Proteins help regulate fluid balance by maintaining osmotic pressure in body fluids, while also buffering pH, preventing drastic changes in acidity, which is vital for cell function.

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What is the recommended daily protein intake?

The recommended daily protein intake for adults is 0.8 grams per kilogram of body weight, though this can vary based on age, activity level, and health status.

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What is protein synthesis?

Protein synthesis is the process of building new proteins, essential for growth, repair, and maintaining bodily functions. High-quality protein sources like whey protein and essential amino acids can boost protein synthesis efficiently.

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Glycemic Load

A measure of how quickly a food raises blood glucose levels, calculated by multiplying the glycemic index of a food by the amount consumed.

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Carbohydrate Oxidation

The conversion of carbohydrates into energy, involving the breakdown of glucose into carbon dioxide, water, and ATP.

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Insulin Resistance

A condition where the body's cells do not respond properly to insulin, leading to high blood sugar levels.

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Glycosylation

The process of glucose binding to proteins, a consequence of high blood sugar levels, which can damage tissues like blood vessels and nerves.

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Basal Metabolic Rate (BMR)

The rate at which the body burns calories while at rest.

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Non-Exercise Activity Thermogenesis (NEAT)

The energy expenditure associated with movement and activity beyond exercise, including fidgeting and daily life tasks.

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Lipogenesis

The process of converting excess glucose into fat, occurring when glycogen stores are full.

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Protein Digestion

The breakdown of proteins into amino acids, occurring in the stomach and small intestine.

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Protein Turnover

The continuous process of protein synthesis and breakdown, recycling amino acids for body needs.

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Essential Amino Acids

Amino acids that cannot be synthesized by the body and must be obtained from the diet.

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Transamination

The process of transferring an amino group from one molecule to another, allowing the synthesis of nonessential amino acids.

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Protein Structure

The unique 3-dimensional shape of a protein, which determines its function.

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Sickle Cell Anemia

The condition caused by a genetic mutation that alters the shape of hemoglobin, leading to sickled red blood cells.

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Protein Digestion

The breakdown of dietary protein into smaller units, including amino acids, dipeptides, and tripeptides, for absorption.

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Protein Turnover

The continuous process of protein synthesis and breakdown, recycling amino acids for body needs.

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What is GLP-1?

GLP-1 is a hormone naturally produced by the intestines, playing a key role in glucose regulation and satiety. Its discovery led to a revolution in diabetes treatment and weight management.

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What is Extendin-4?

Extendin-4 is a protein discovered in Gila monsters, possessing similar effects to GLP-1, including blood glucose lowering and prolonged action.

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What is the "Intestinal Brake"?

The "Intestinal Brake" mechanism refers to the role of the small intestine in regulating blood glucose and appetite through GLP-1 release.

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How does GLP-1 affect weight?

GLP-1 treatment results in significant weight loss due to its effects on appetite suppression and increased satiety.

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What are the clinical benefits of GLP-1?

GLP-1 improves various clinical outcomes in diabetes and other conditions, including reduced cardiovascular risk and kidney complications.

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What makes people more susceptible to the negative effects of carbohydrates?

Simple carbohydrates, especially fructose, can lead to increased triglyceride levels, making individuals more sensitive to the negative effects of dietary carbohydrates.

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What factors amplify the negative effects of carbs?

Obesity, insulin resistance, high fasting triglycerides, and postmenopausal status can enhance the negative impact of a high carbohydrate diet on the body.

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What is the recommended approach to carbohydrate intake?

A balanced diet with moderate carbohydrate intake, focusing on complex carbohydrates and fiber-rich foods, is recommended for optimal health.

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Study Notes

Obesity Statistics and Prevalence

  • Obesity is increasing globally; in the US, it rose from 15% in 1976-80 to 33% in adults today.
  • Youth are increasingly affected, making it a growing concern.
  • Obesity is strongly linked to significant health problems such as cardiovascular disease, diabetes, liver disease, and other serious conditions, becoming a major cause of death.

Obesity as a Disorder

  • Obesity is characterized by having excessive body fat relative to lean tissue.
  • It is frequently diagnosed using Body Mass Index (BMI).
  • BMI > 30 is categorized as obese, while BMI > 27 is considered overweight.
  • Importantly, BMI is not a perfect measure; a more accurate assessment involves determining body fat stores, and criteria for classification vary by age, sex, and ethnicity.

Demographics and Prevalence

  • Obesity prevalence is more pronounced among lower socio-economic groups in developed, western countries.
  • This trend opposes historical patterns.
  • Recent data indicates high prevalence in minority groups in the US, and increases are notable in several developing regions like Asia, South America, urban Africa, and central Europe.
  • Historically, obesity was uncommon, but it is now a common occurrence.

Diseases Associated with Obesity

  • Obesity is strongly linked to several diseases and conditions, including:
    • Cancers (especially colon, prostate, and breast)
    • Sleep and breathing disorders
    • High blood pressure
    • Gall bladder disease
    • Dyslipidemia (lipid disorders)
    • Reproductive dysfunction
    • Cardiovascular disease, stroke
    • Liver disease (NAFLD)
    • Depression
    • Cognitive impairment (e.g., Alzheimer's).

Nutritional Interventions in the Past

  • Pellagra was dramatically reduced by niacin fortification in bread.
  • Rickets incidence declined substantially due to vitamin D supplementation in milk and other foods.
  • Iodine addition to salt helped control endemic goiter and cretinism.
  • Beriberi was largely eliminated by thiamine supplementation, particularly for rice consumption.
  • Vitamin C supplementation effectively prevented scurvy.
  • Iron and folate supplementation reduced anemia, a major problem in women, especially pregnant women
  • Pernicious anemia was cured via monthly vitamin B12 injections.

Gastric Phase

  • Food entering the stomach—smell, taste, sight of food—stimulates gastric secretions as part of preparation, involving signals from the brain. This phase also controls the passage of food from the stomach to the intestines.
  • Stomach acid, enzymes, such as HCI, pepsin, and gastric lipase, and hormones (e.g. gastrin) facilitate digestion.
  • Intrinsic factor, needed for vitamin B12 absorption, is secreted.

Intestinal Phase

  • Entry of food into the small intestine triggers hormonal responses in the small intestine, initiating a process to slow and regulate gastric secretion.
  • Stomach motility is reduced to allow proper digestion by the intestines.
  • Pancreatic and intestinal enzymes, such as bicarbonate, are secreted by the intestines to help further digest carbohydrates into sugars.

Digestion of Nutrients

  • Other functions of the GI tract include: regulating nutrients and fluids, defending against infections, absorbing fluids and electrolytes, and producing important hormones and bioactive compounds.

Macronutrients Summary

  • All foods need macronutrients: carbohydrates, proteins, fats, vitamins, and minerals.
  • Carbohydrates are a primary energy source for the body and come in different forms (simple and complex).
  • Simple carbohydrates are made of a single sugar molecule.
  • Complex carbohydrates are made of multiple sugar units, found in many plant-based sources.
    • Refined grains are commonly stripped of many of their nutrients during processing. Whole grains retain essential nutrients.
  • Fats are essential; they provide energy and are crucial for hormone production and cell structure. A variety of fats is important.
  • Protein functions include structure and enzyme production; it's a key component in many bodily functions.

Obesity Considerations in the context of Diet

  • High-fructose corn syrup intake is correlated with increased obesity rates.
  • Whole-grain foods provide a combination of carbohydrates, vitamins, minerals and fiber that are beneficial for health.
  • People with varied diets and diverse needs require varying amounts of macronutrients like carbohydrates and proteins for optimal energy and nutrient intake.
  • High carbohydrate diets can also lead to weight loss if coupled with decreased fat intake.

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