Podcast
Questions and Answers
Usually food has what effect on drug dissolution and absorption?
Usually food has what effect on drug dissolution and absorption?
What occurs during the vascular phase of inflammation?
What occurs during the vascular phase of inflammation?
Vasodilation with increased capillary permeability
What should concern the nurse about a client taking NSAIDs who complains of heartburn?
What should concern the nurse about a client taking NSAIDs who complains of heartburn?
Further investigation is needed
How does the NSAID work?
How does the NSAID work?
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What is a common symptom of early toxicity related to aspirin?
What is a common symptom of early toxicity related to aspirin?
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What is the half-life of aspirin in large doses?
What is the half-life of aspirin in large doses?
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Which manifestations should concern the nurse regarding large doses of aspirin?
Which manifestations should concern the nurse regarding large doses of aspirin?
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What should concern the RN about a 25-year-old client with asthma prescribed aspirin?
What should concern the RN about a 25-year-old client with asthma prescribed aspirin?
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Which route of drug absorption has the greatest bioavailability?
Which route of drug absorption has the greatest bioavailability?
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What is the best description of a drug's serum half-life?
What is the best description of a drug's serum half-life?
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Which factors most commonly affect a drug's action? (Select all that apply)
Which factors most commonly affect a drug's action? (Select all that apply)
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Excretion or elimination primarily occurs by which organ?
Excretion or elimination primarily occurs by which organ?
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What is the best determinant of the biologic activity of a drug?
What is the best determinant of the biologic activity of a drug?
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Which type of drug prevents or inhibits a cellular response?
Which type of drug prevents or inhibits a cellular response?
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Which indicator measures the margin of safety of a drug?
Which indicator measures the margin of safety of a drug?
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To avoid drug toxicity, how often should blood levels be drawn?
To avoid drug toxicity, how often should blood levels be drawn?
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What information should the nurse provide to an individual taking NSAIDs? (Select all that apply)
What information should the nurse provide to an individual taking NSAIDs? (Select all that apply)
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Which statement is true regarding anti-gout agents?
Which statement is true regarding anti-gout agents?
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When discontinuing steroid therapy, how many days should the dosage be tapered over?
When discontinuing steroid therapy, how many days should the dosage be tapered over?
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What information should be included when planning patient education regarding antigout drugs? (Select all that apply)
What information should be included when planning patient education regarding antigout drugs? (Select all that apply)
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Which factor is most relevant to the relief of chronic pain?
Which factor is most relevant to the relief of chronic pain?
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What is the opioid antagonist used to treat an overdose of morphine-like substances?
What is the opioid antagonist used to treat an overdose of morphine-like substances?
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Withdrawal symptoms usually occur how many hours after the opioid dose?
Withdrawal symptoms usually occur how many hours after the opioid dose?
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What should the RN assess to check if a client taking morphine for post-operative pain is having side effects?
What should the RN assess to check if a client taking morphine for post-operative pain is having side effects?
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What should the client do if they experience dizzy spells while taking morphine?
What should the client do if they experience dizzy spells while taking morphine?
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Study Notes
Drug Effects on Absorption
- Food generally interferes with drug dissolution and absorption.
Inflammation Response
- Vascular phase of inflammation includes vasodilation and increased capillary permeability.
NSAID Side Effects
- Common side effect of NSAIDs includes heartburn; further investigation may be necessary if reported by clients.
Mechanism of NSAIDs
- NSAIDs inhibit synthesis of prostaglandins, which reduces pain and inflammation.
Aspirin Use Considerations
- Tinnitus is an early symptom of aspirin toxicity.
- Aspirin has a half-life of approximately 15-30 hours when taken in large doses.
- Aspirin not taken at mealtime may cause gastrointestinal distress.
Aspirin and Asthma
- In asthmatic patients, aspirin can trigger bronchospasms and should be used with caution.
Drug Absorption Bioavailability
- Intravenous (IV) route has the greatest bioavailability among drug absorption methods.
Drug Half-Life Definition
- A drug’s serum half-life is defined as the time required for half of the drug to be eliminated after absorption.
Factors Affecting Drug Action
- Common factors affecting drug action include poor circulation, pain, stress, hunger, and fasting.
Drug Excretion
- The kidneys are primarily responsible for the excretion or elimination of drugs from the body.
Drug Activity Determinant
- The fit of the drug at the receptor site is the best determinant of its biological activity.
Drug Response Inhibition
- Antagonists are drugs that prevent or inhibit a cellular response.
Therapeutic Index
- The therapeutic index measures the margin of safety of a drug.
Monitoring Drug Toxicity
- Blood levels should be drawn at periodic intervals to avoid drug toxicity.
NSAID Patient Education
- Clients should report epigastric distress.
- Observation for tarry stools and bruising is critical during extended NSAID use.
- Clients should avoid NSAIDs during heavy menstrual flow.
Anti-Gout Agent Facts
- Colchicine is used for managing acute gout attacks.
Steroid Therapy Withdrawal
- When discontinuing steroids, the dosage should be tapered over 5 to 10 days.
- Increased fluid intake is advised during tapering.
Antigout Drug Education
- Patients should avoid alcohol, caffeine, and high-purine foods.
- Medications should be taken with food.
Chronic Pain Management
- Use of drugs with long half-lives is relevant to effectively relieve chronic pain.
Opioid Antagonist
- Naloxone is the opioid antagonist used to treat morphine-like overdoses.
Opioid Withdrawal Symptoms
- Withdrawal symptoms typically occur 8 to 24 hours after an opioid dose.
Monitoring Morphine Side Effects
- Assess for urinary retention in clients taking morphine for post-operative pain.
Morphine Side Effects and Safety
- Clients taking morphine should be advised to move slowly to avoid dizziness and falls.
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Description
This quiz covers key topics related to pharmacology as part of the NUR 334 course. Questions involve drug dissolution, the vascular phase of inflammation, and NSAIDs side effects. It's essential for nursing students preparing for their exam.
