Nucleotide Metabolism and DNA Structure Lecture
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Questions and Answers

Which enzyme is responsible for catalyzing the breakdown of uric acid to allantoin?

  • Recombinant uricase (correct)
  • AMP deaminase
  • Nucleotidase
  • Adenosine deaminase

    • Which type of gout is caused by inherited abnormalities of enzymes of purine metabolism?

  • Secondary gout
  • Lactic acidosis
  • Renal failure
  • Primary gout (correct)

    • What are the degradation products of nucleotidase and phosphatase acting on NMP?

  • Nucleoside phosphorylase
  • Nucleosidase
  • Base and Ribose
  • Nucleoside and H2O (correct)

    • What is the rate at which a healthy adult human excretes uric acid in 24 hours?

    <p>0.6 g</p> Signup and view all the answers

    Which pathway involves the breakdown of purine and pyrimidine nucleotides?

    <p>Salvage pathways of nucleotide synthesis</p> Signup and view all the answers

    What is the structure of a nucleotide?

    <p>Five-carbon sugar, nitrogenous base, phosphate</p> Signup and view all the answers

    Which molecule serves as an activated precursor of DNA and RNA?

    <p>ATP</p> Signup and view all the answers

    What is the function of nucleotides as coenzymes?

    <p>Structural moieties of coenzymes</p> Signup and view all the answers

    What occurs to ingested nucleic acids in the duodenum?

    <p>Denaturation by low pH</p> Signup and view all the answers

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