Nucleotide Metabolism and DNA Structure Lecture
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Questions and Answers

Which enzyme is responsible for catalyzing the breakdown of uric acid to allantoin?

  • Recombinant uricase (correct)
  • AMP deaminase
  • Nucleotidase
  • Adenosine deaminase

Which type of gout is caused by inherited abnormalities of enzymes of purine metabolism?

  • Secondary gout
  • Lactic acidosis
  • Renal failure
  • Primary gout (correct)

What are the degradation products of nucleotidase and phosphatase acting on NMP?

  • Nucleoside phosphorylase
  • Nucleosidase
  • Base and Ribose
  • Nucleoside and H2O (correct)

What is the rate at which a healthy adult human excretes uric acid in 24 hours?

<p>0.6 g (B)</p> Signup and view all the answers

Which pathway involves the breakdown of purine and pyrimidine nucleotides?

<p>Salvage pathways of nucleotide synthesis (D)</p> Signup and view all the answers

What is the structure of a nucleotide?

<p>Five-carbon sugar, nitrogenous base, phosphate (A)</p> Signup and view all the answers

Which molecule serves as an activated precursor of DNA and RNA?

<p>ATP (B)</p> Signup and view all the answers

What is the function of nucleotides as coenzymes?

<p>Structural moieties of coenzymes (A)</p> Signup and view all the answers

What occurs to ingested nucleic acids in the duodenum?

<p>Denaturation by low pH (D)</p> Signup and view all the answers

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