Nucleophilic Substitution Reactions

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5 Questions

Which of the following best describes a nucleophilic substitution reaction?

A reaction in which an electron-rich species replaces a functional group in an electron-deficient molecule

What is the role of the nucleophile in a nucleophilic substitution reaction?

It attacks the substrate and bonds with it

What is the principal product of a nucleophilic substitution reaction?

R-Nuc

Which of the following can be a nucleophile in a nucleophilic substitution reaction?

All of the above

What is the leaving group in a nucleophilic substitution reaction?

LG

Study Notes

Nucleophilic Substitution Reaction

  • A nucleophilic substitution reaction is a type of organic reaction where a nucleophile replaces a leaving group in a substrate.

Nucleophile's Role

  • The nucleophile plays a crucial role in a nucleophilic substitution reaction by donating an electron pair to form a new bond with the substrate.

Principal Product

  • The principal product of a nucleophilic substitution reaction is a new compound with a new bond between the substrate and the nucleophile.

Nucleophile Examples

  • Examples of nucleophiles in a nucleophilic substitution reaction include negatively charged species like Cl-, OH-, and CN-, as well as neutral species with a lone pair of electrons like NH3 and H2O.

Leaving Group

  • The leaving group in a nucleophilic substitution reaction is a group that leaves the substrate, forming a new bond with the nucleophile, and is typically a stable molecule or ion with a weak bond to the substrate.

Test your knowledge of nucleophilic substitution reactions in chemistry with this quiz! Learn about nucleophiles, electrophiles, and substrates as you answer questions about this important class of chemical reactions.

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