Nucleophilic Substitution Mechanisms Quiz
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Questions and Answers

In the SN1 mechanism, the rate-determining step involves:

  • Simultaneous attack of the nucleophile and departure of the leaving group
  • Direct interaction between the nucleophile and the substrate
  • Formation of a carbocation (correct)
  • Partial attachment of the nucleophile to the carbon before departure of the leaving group
  • The SN2 mechanism is characterized by:

  • Formation of a stable carbocation intermediate
  • Partial attachment of the nucleophile to the carbon before departure of the leaving group
  • Multiple steps involving the nucleophile and leaving group
  • Simultaneous displacement of the leaving group and attack by the nucleophile (correct)
  • In the hydrolysis of bromomethane in aqueous base, the energy necessary for breaking the C-Br bond is supplied by:

  • Formation of the HO-C bond (correct)
  • Formation of a stable carbocation intermediate
  • Approach by -OH along the line of centers of the C & Br
  • Quantum mechanical calculation
  • The approach by -OH along the line of centers of the C & Br is associated with:

    <p>Lowest energy for the reaction</p> Signup and view all the answers

    The transition state for SN2 mechanism involves:

    <p>Inversion of configuration (Walden inversion)</p> Signup and view all the answers

    In the SN1 mechanism, the rate of the reaction depends on:

    <p>The concentration of the alkyl halide only</p> Signup and view all the answers

    In the SN2 mechanism, the stereochemistry of the product shows:

    <p>Inversion of configuration</p> Signup and view all the answers

    In the hydrolysis of bromomethane in aqueous base, the rate-determining step involves:

    <p>Partial attachment of -OH to carbon before Br- is fully detached</p> Signup and view all the answers

    In the SN2 mechanism, the nucleophile attacks the carbon atom:

    <p>Along the line of centers of the C &amp; Br</p> Signup and view all the answers

    The hydrolysis of bromomethane in aqueous base is classified as:

    <p>Bimolecular</p> Signup and view all the answers

    Study Notes

    SN1 Mechanism

    • The rate-determining step involves a unimolecular process
    • The rate of the reaction depends on the concentration of the substrate

    SN2 Mechanism

    • Characterized by a bimolecular process
    • The transition state involves a pentacoordinate carbon atom
    • The nucleophile attacks the carbon atom from the backside, resulting in an inversion of stereochemistry
    • Stereochemistry of the product shows an inversion of configuration

    Hydrolysis of Bromomethane

    • The energy necessary for breaking the C-Br bond is supplied by the aqueous base
    • The rate-determining step involves a bimolecular process
    • Classified as an SN2 reaction

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    Description

    Test your knowledge of nucleophilic substitution mechanisms with this quiz covering SN1 and SN2 reactions. Challenge yourself to understand the differences between unimolecular and bimolecular substitution processes.

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