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Questions and Answers
Draw a nucleotide and label the three main parts.
Draw a nucleotide and label the three main parts.
Nucleotide consists of a base, a deoxyribose sugar, and a phosphate.
Which of the following represent purine and pyrimidine nucleotides?
Which of the following represent purine and pyrimidine nucleotides?
Explain why the pairing of one purine with one pyrimidine is important to the shape of a DNA molecule.
Explain why the pairing of one purine with one pyrimidine is important to the shape of a DNA molecule.
It maintains a constant distance between the deoxyribose backbones.
Define 'complementary base pairing.'
Define 'complementary base pairing.'
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Explain the difference between a nucleotide and a 'base.'
Explain the difference between a nucleotide and a 'base.'
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Explain how the structure of DNA is important to its function as an information storage molecule.
Explain how the structure of DNA is important to its function as an information storage molecule.
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List three structural differences between DNA and RNA.
List three structural differences between DNA and RNA.
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Describe the importance of phosphodiester bonds and hydrogen bonds to the structure of DNA and RNA molecules.
Describe the importance of phosphodiester bonds and hydrogen bonds to the structure of DNA and RNA molecules.
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Calculate the percentage of each of the nucleotides in a DNA molecule if the percentage of one of the nucleotides is known.
Calculate the percentage of each of the nucleotides in a DNA molecule if the percentage of one of the nucleotides is known.
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Describe how a phosphodiester bond is formed between two nucleotides.
Describe how a phosphodiester bond is formed between two nucleotides.
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Predict the effect of increasing temperature on the structure of DNA and RNA molecules.
Predict the effect of increasing temperature on the structure of DNA and RNA molecules.
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Explain how the structure of DNA makes it possible for a cell to make exact copies of its chromosomes quickly and with very few errors.
Explain how the structure of DNA makes it possible for a cell to make exact copies of its chromosomes quickly and with very few errors.
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Explain why the two strands in a DNA molecule are described as antiparallel to each other.
Explain why the two strands in a DNA molecule are described as antiparallel to each other.
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Study Notes
Nucleotides and Their Structure
- A nucleotide consists of three main components: a nitrogenous base, a deoxyribose sugar, and a phosphate group.
- Purine nucleotides include adenine (A) and guanine (G); pyrimidine nucleotides consist of cytosine (C) and thymine (T).
Importance of Base Pairing
- Pairing one purine with one pyrimidine maintains a consistent distance of three carbon rings between deoxyribose backbones, critical for the DNA structure.
- "Complementary base pairing" refers to specific hydrogen bonds that form between bases across the two strands of DNA.
Nucleotides vs. Bases
- The term "base" specifically refers to one of the nitrogenous bases (A, G, C, T).
- One nucleotide is made up of a base, a sugar, and a phosphate; there are four types of nucleotides corresponding to four nitrogenous bases.
DNA Structure and Function
- DNA stores genetic information via its double helix structure, consisting of two intertwined backbones and base pairs.
- Bases are linked by hydrogen bonds, creating "bridges" between the strands that stabilize the entire structure.
Structural Differences Between DNA and RNA
- DNA features adenine, thymine, guanine, and cytosine as bases, while RNA replaces thymine with uracil (U).
- DNA contains deoxyribose sugar; RNA contains ribose sugar.
- DNA is double-stranded; RNA exists as a single strand.
Bonds in Nucleic Acids
- Hydrogen bonds stabilize DNA structure, holding complementary nucleotide bases together.
- Phosphodiester bonds connect nucleotides in both DNA and RNA, forming the backbone of these nucleic acid molecules.
Calculating Nucleotide Percentages
- If one percentage of a nucleotide is known, the percentage can be calculated for complementary nucleotides; e.g., if T is 28%, then A is also 28%.
Formation of Phosphodiester Bonds
- A phosphodiester bond is created when a phosphate group links the 5' carbon of one nucleotide to the 3' carbon of another, forming a 3'-5' phosphodiester bridge.
Effects of Temperature on Nucleic Acids
- Increasing temperature leads to DNA unwinding and the breaking of hydrogen bonds, resulting in denaturation and formation of single strands.
DNA Replication Mechanism
- DNA replication occurs before cell division, with each strand serving as a template for creating a complementary strand, ensuring accuracy and fidelity of genetic information.
Antiparallel Nature of DNA Strands
- DNA strands run in opposite directions (3' to 5' and 5' to 3'), facilitating stable hydrogen bonding between complementary bases, critical for the double helix formation.
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Description
Test your knowledge of nucleic acids with these flashcards that cover the structure of nucleotides and their importance in DNA. Learn about purines and pyrimidines and their role in maintaining the DNA structure. Perfect for biology students studying genetics and molecular biology.