CHAPTER 49
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Questions and Answers

Which types of effects are possible therapeutic effects of nonsteroidal anti-inflammatory drugs (NSAIDs)?

  • Diuretic effects
  • Antimicrobial effects
  • Antipyretic effects (correct)
  • Anxiolytic effects

A 75-year-old female patient has been given naproxen sodium (Aleve®) for the treatment of rheumatoid arthritis. Which type of medication will have a possible interaction with this NSAID?

  • Antibiotics
  • Antihistamines
  • Decongestants
  • Anticoagulants (correct)

An older adult patient tells the nurse that he uses acetylsalicylic acid for "anything that ails me." What are the most common signs of chronic salicylate intoxication in adults?

  • Photosensitivity and nervousness
  • Acute gastrointestinal bleeding and anorexia
  • Tinnitus and hearing loss (correct)
  • Hyperventilation and central nervous system (CNS) effects

A patient is being treated with allopurinol (Zyloprim®) for gout. Which therapeutic result should the nurse monitor for?

<p>Decreased uric acid levels (D)</p> Signup and view all the answers

A patient is prescribed colchicine for the treatment of gout. What important information should the nurse give the patient about this drug?

<p>Report to the health care provider the occurrence of increased pain, blood in the urine, or excessive fatigue. (C)</p> Signup and view all the answers

A 55-year-old female patient is being administered ketorolac intramuscularly. What information should the nurse give this patient about this drug?

<p>The medication is given slowly intramuscularly into a large muscle mass. (A)</p> Signup and view all the answers

If a child has a fever, the nurse will likely suggest which medication?

<p>ibuprofen (Motrin®) (D)</p> Signup and view all the answers

A patient has used buffered acetylsalicylic acid (Aspirin) for several years as treatment for osteoarthritis. However, the patient's symptoms are worsening, and now something stronger is needed. The physician prescribes an NSAID and misoprostol. The patient asks the nurse why two pills now have to be taken for the arthritis. Which is the nurse's best response to the patient?

<p>Misoprostol may help to prevent gastric ulcers that may occur when taking NSAIDs. (C)</p> Signup and view all the answers

A patient who has a history of coronary artery disease has been instructed to take one 81-mg tablet of acetylsalicylic acid (Aspirin) each day. What is the purpose of this dose of acetylsalicylic acid?

<p>To prevent thrombus formation (D)</p> Signup and view all the answers

Which natural health product is sometimes used to treat the pain of osteoarthritis?

<p>Glucosamine (A)</p> Signup and view all the answers

Which are contraindications to the use of NSAIDs? (Select all that apply.)

<p>Rhinitis (A), Peptic ulcer disease (C), Epistaxis (E), Breastfeeding (G)</p> Signup and view all the answers

Flashcards

NSAIDs: Antipyretic Effects

Reduce fever.

NSAIDs & Anticoagulant Interaction

Increased bleeding risk due to platelet inhibition.

Chronic Salicylate Intoxication (Adults)

Tinnitus and hearing loss.

Allopurinol Therapeutic Effect

Decreased uric acid levels.

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Colchicine: When to Report Symptoms

Report increased pain, blood in urine, or fatigue to the doctor.

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Ketorolac Administration (IM)

Administer intramuscular injections slowly, into a large muscle mass.

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Antipyretic for Children

Ibuprofen.

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Misoprostol with NSAIDs

Prevent gastric ulcers from NSAIDs.

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Low-Dose Aspirin Purpose

Prevent thrombus (clot) formation.

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Natural Remedy for Osteoarthritis Pain

Glucosamine.

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NSAIDs Contraindications

Rhinitis, peptic ulcer disease, breastfeeding, epistaxis.

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What are antipyretic effects?

Nonsteroidal anti-inflammatory drugs reduce fever.

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Naproxen sodium interactions?

Naproxen sodium interacts with anticoagulants leading to increased bleeding risk.

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What are signs of salicylate intoxication?

The most common signs of chronic salicylate (aspirin) intoxication are ringing in the ears and hearing loss.

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Monitoring for gout treatment

Monitor for decreased uric acid levels.

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Adverse effects of colchicine

Report symptoms of increased pain fatigue and blood in the urine.

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Ketorolac administration information

It should be administered slowly intramuscularly into a large muscle mass.

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Treatment for a child with a temperature

Likely suggest ibuprofen (Motrin).

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Why is misoprostol prescribed with and NSAID

May help to prevent gastric ulcers.

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Purpose of 81-mg tablet of acetylsalicylic acid (Aspirin)

To prevent thrombus formation

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What treats oa pain?

Glucosamine

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Contraindications for using NSAIDs

NSAIDs are not use if breastfeeding.

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NSAIDs treat what?

NSAIDs have what effects?

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Naproxen sodium interaction warning?

Anticoagulants may increase risk factors.

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Effects of Salicylate?

Hearing loss.

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Treating gout effectively?

Treatment leads to decrease in levels.

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Adverse effects of colchicine and when to report

Colchicine treatment requirements?

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Ketorolac intramuscularly info?

Dosage is not to exceed a 5-7 day time period.

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A children's Tylenol subsitute

Ibuprofen

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The main purpose of Misoprostol

Misoprostol helps reduce gastric irritation.

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NSAIDs side effect

Contraindications to NSAIDs include conditions that increase bleeding risk.

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Study Notes

  • Nonsteroidal anti-inflammatory drugs (NSAIDs) can have antipyretic effects.
  • A potential interaction with naproxen sodium (Aleve) prescribed for rheumatoid arthritis may occur with anticoagulants, increasing bleeding tendencies due to platelet inhibition and hypoprothrombinemia.
  • Tinnitus and hearing loss are common signs of chronic salicylate intoxication in adults.
  • Allopurinol (Zyloprim) treatment for gout should lead to a decrease in uric acid levels.
  • Colchicine may cause renal effects so report increased pain, blood in the urine, or excessive fatigue immediately.
  • Ketorolac should be administered intramuscularly slowly into a large muscle mass with dosing not exceeding 5-7 days.
  • Ibuprofen is available over-the-counter for fever reduction.
  • Aspirin is not recommended for children younger than 12 due to the risk of Reye's syndrome.
  • Misoprostol is prescribed with NSAIDs to help prevent gastric ulcers by inhibiting gastric acid secretions and stimulating mucous secretions.
  • Low-dose acetylsalicylic acid (Aspirin) is taken daily to prevent thrombus formation by reducing platelet aggregation, beneficial for adults with high risk factors for coronary artery disease or stroke.
  • Glucosamine can be used individually or with chondroitin to treat pain from osteoarthritis.
  • Contraindications to NSAID use include:
    • Rhinitis due to the risk of nosebleeds
    • Peptic ulcer disease
    • Breastfeeding

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Description

Overview of NSAIDs, their antipyretic effects, and interactions. Focus on drugs like naproxen, allopurinol, colchicine, ketorolac, ibuprofen, aspirin and misoprostol. Highlights potential side effects and precautions

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