Recent Lessons

Show all results for ""

Feature Overview

Ace your exams with our all-in-one platform for creating and sharing quizzes and tests.

Quizzes

Create quizzes and tests automatically from your content using AI.

Flashcards

Automatically turn your notes into digital flashcards.

Share, Export & Embed

Share with classmates or export to Excel and your learning management system.

Stats & Reporting

Auto-grading quizzes and tests with detailed stats and reports.

Mobile Apps

The smarter way to study – wherever you are.

Pricing

Search...

5 Questions

100 Views

Norepinephrine Flashcards

Choose a study mode

Play Quiz

Study Flashcards

Spaced Repetition

Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the generic or trade name for Norepinephrine?

Adrenaline

Levophed (correct)

Epinephrine

Dopamine

What is the classification of Norepinephrine?

Sympathomimetic / Sympathetic agonist / Catecholamine

Describe the primary mechanism of action of Norepinephrine.

Primary a1 agonist --> second messenger release of Ca2+ in VSMC --> peripheral vasoconstriction --> increased SVR --> increased BP

What is the secondary mechanism of action of Norepinephrine?

<p>B1 agonist --> increased intracellular Ca2+ in cardiac cells --> + inotropy, dromotropy, chronotropy</p> Signup and view all the answers

What are the pharmacokinetics of Norepinephrine regarding onset?

<p>Not provided</p> Signup and view all the answers

Study Notes

Norepinephrine Overview

Norepinephrine is also known by its trade name, Levophed.
Classified as a sympathomimetic drug, sympathetic agonist, and catecholamine.

Mechanism of Action

Acts primarily as an alpha-1 (α1) agonist, leading to increased calcium ion (Ca2+) release in vascular smooth muscle cells (VSMC).
Results in peripheral vasoconstriction, which elevates systemic vascular resistance (SVR) and blood pressure (BP).
Functions secondarily as a beta-1 (β1) agonist, enhancing intracellular calcium levels in cardiac cells.
This secondary action promotes increased myocardial contractility (positive inotropy), conduction velocity (positive dromotropy), and heart rate (positive chronotropy).

Pharmacokinetics

Norepinephrine has an onset of action that needs to be detailed further, as the specific timings were not provided.

Studying That Suits You

Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

Description

Test your knowledge of norepinephrine with these flashcards. Each card covers essential information including its generic name, classification, and mechanism of action. Perfect for students and professionals in pharmacology or related fields.