Noninvasive Prenatal Screening Guideline Development

Developing a guideline for the use of NIPS for pregnant individuals at general risk for trisomies. (correct)

Reviewing the existing guidelines for traditional prenatal screenings.

Conducting a study on the prevalence of fetal trisomies in twin gestations.

Evaluating the utility of invasive prenatal screening methods for chromosomal disorders.

Grading of Recommendations Assessment, Development, and Evaluation Evidence to Decision framework (correct)

Peer Evaluation and Clinical Assessment System

American College of Medical Genetics and Genomics Review Process

Grading System for Clinical Practice Guidelines

There is no significant difference in accuracy between NIPS and traditional methods.

NIPS is less accurate than traditional methods.

NIPS is more accurate for trisomies 21, 18, and 13 in singleton and twin gestations. (correct)

NIPS has limited utility in detecting chromosomal disorders.

<p>Detection of rare autosomal trisomies and other microdeletion syndromes</p> Signup and view all the answers

<p>Offering NIPS to screen for fetal sex chromosome aneuploidy</p> Signup and view all the answers

<p>Extensive internal and external peer review with a public comment period</p> Signup and view all the answers