Podcast
Questions and Answers
A patient on a ventilator has low ventilation pressures and is hypoxic. List three possible causes.
A patient on a ventilator has low ventilation pressures and is hypoxic. List three possible causes.
Ventilator circuit leak, endotracheal tube cuff leak, or esophageal intubation.
What specific score, within an established system, is the target when managing sedation for a patient on mechanical ventilation?
What specific score, within an established system, is the target when managing sedation for a patient on mechanical ventilation?
A Richmond Agitation Sedation Score (RASS) between -2 and 0.
Explain what physiological mechanism is behind the reduction in venous return associated with positive pressure ventilation.
Explain what physiological mechanism is behind the reduction in venous return associated with positive pressure ventilation.
Increased intrathoracic pressure from positive pressure ventilation compresses the heart and great vessels reducing venous return.
Aside from respiratory failure, what is the other primary indication for providing mechanical ventilation?
Aside from respiratory failure, what is the other primary indication for providing mechanical ventilation?
Compare and contrast spontaneous breathing and positive pressure ventilation with regards to their effect on intrathoracic pressure.
Compare and contrast spontaneous breathing and positive pressure ventilation with regards to their effect on intrathoracic pressure.
In what specific scenarios, despite general avoidance, might Noninvasive Positive-Pressure Ventilation (NPPV) be considered?
In what specific scenarios, despite general avoidance, might Noninvasive Positive-Pressure Ventilation (NPPV) be considered?
What is a key difference in the pressure delivery mechanism between BiPAP and CPAP?
What is a key difference in the pressure delivery mechanism between BiPAP and CPAP?
Compare the method of breath delivery between Pressure-Controlled (PC) and Volume-Controlled (VC) ventilation.
Compare the method of breath delivery between Pressure-Controlled (PC) and Volume-Controlled (VC) ventilation.
Describe how Assist-Control (A/C) mode ensures a minimum ventilation rate compared to Synchronized Intermittent-Mandatory Ventilation (SIMV).
Describe how Assist-Control (A/C) mode ensures a minimum ventilation rate compared to Synchronized Intermittent-Mandatory Ventilation (SIMV).
What condition is the maximum recommended plateau pressure during mechanical ventilation trying to avoid?
What condition is the maximum recommended plateau pressure during mechanical ventilation trying to avoid?
If a patient exhibits increasingly elevated ventilation pressures, name 3 potential causes that must be investigated.
If a patient exhibits increasingly elevated ventilation pressures, name 3 potential causes that must be investigated.
How does the concept of 'variable' differ between PC and VC ventilation in terms of what is being actively controlled?
How does the concept of 'variable' differ between PC and VC ventilation in terms of what is being actively controlled?
Can both A/C and SIMV ventilation modes be applied using pressure and volume-controlled setups? Explain why or why not.
Can both A/C and SIMV ventilation modes be applied using pressure and volume-controlled setups? Explain why or why not.
What is the first-line therapy for COPD exacerbations and acute cardiogenic pulmonary edema (ACPE)?
What is the first-line therapy for COPD exacerbations and acute cardiogenic pulmonary edema (ACPE)?
When should NPPV generally be avoided?
When should NPPV generally be avoided?
What are two conditions where NPPV might still be used despite being generally avoided?
What are two conditions where NPPV might still be used despite being generally avoided?
What are the initial pressure settings for BiPAP?
What are the initial pressure settings for BiPAP?
Flashcards
Richmond Agitation Sedation Scale (RASS)
Richmond Agitation Sedation Scale (RASS)
A scoring system used to assess the level of sedation in mechanically ventilated patients, aiming for a score between -2 and 0.
Hypoxia
Hypoxia
A condition where the body's tissues and organs do not receive enough oxygen.
Positive-Pressure Ventilation
Positive-Pressure Ventilation
A technique that uses positive pressure to deliver air into the lungs, which can affect hemodynamics by increasing intrathoracic pressure, reducing venous return, and decreasing cardiac output.
Reasons for Ventilatory Support
Reasons for Ventilatory Support
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Hypotension after Ventilation
Hypotension after Ventilation
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What is the first-line therapy for COPD exacerbations and acute cardiogenic pulmonary edema (ACPE)?
What is the first-line therapy for COPD exacerbations and acute cardiogenic pulmonary edema (ACPE)?
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When should NPPV be generally avoided?
When should NPPV be generally avoided?
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What is the difference between BiPAP and CPAP?
What is the difference between BiPAP and CPAP?
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How often should BiPAP settings be evaluated?
How often should BiPAP settings be evaluated?
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How does pressure-controlled ventilation (PC) differ from volume-controlled ventilation (VC)?
How does pressure-controlled ventilation (PC) differ from volume-controlled ventilation (VC)?
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How does synchronized intermittent-mandatory ventilation (SIMV) differ from assist-control (A/C) ventilation?
How does synchronized intermittent-mandatory ventilation (SIMV) differ from assist-control (A/C) ventilation?
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What might elevated ventilation pressures indicate?
What might elevated ventilation pressures indicate?
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What is the maximum recommended plateau pressure during mechanical ventilation?
What is the maximum recommended plateau pressure during mechanical ventilation?
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Noninvasive Positive-Pressure Ventilation (NPPV)
Noninvasive Positive-Pressure Ventilation (NPPV)
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What is the first-line therapy for COPD exacerbations and ACPE?
What is the first-line therapy for COPD exacerbations and ACPE?
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When should NPPV generally be avoided?
When should NPPV generally be avoided?
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When might NPPV still be used despite being generally avoided?
When might NPPV still be used despite being generally avoided?
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What is the main advantage of volume-controlled ventilation (VC)?
What is the main advantage of volume-controlled ventilation (VC)?
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What does Assist-Control (A/C) ventilation deliver?
What does Assist-Control (A/C) ventilation deliver?
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How does Synchronized Intermittent-Mandatory Ventilation (SIMV) differ from A/C?
How does Synchronized Intermittent-Mandatory Ventilation (SIMV) differ from A/C?
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Can A/C and SIMV be used with PC and VC modes?
Can A/C and SIMV be used with PC and VC modes?
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What are the initial pressure settings for BiPAP?
What are the initial pressure settings for BiPAP?
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What could low ventilation pressures combined with hypoxia suggest?
What could low ventilation pressures combined with hypoxia suggest?
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What scoring system is recommended for managing sedation in mechanically ventilated patients?
What scoring system is recommended for managing sedation in mechanically ventilated patients?
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What is the target RASS score for sedation?
What is the target RASS score for sedation?
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Why should prolonged neuromuscular blockade be avoided?
Why should prolonged neuromuscular blockade be avoided?
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How does spontaneous breathing create airflow into the lungs?
How does spontaneous breathing create airflow into the lungs?
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What happens to venous return and cardiac output during positive-pressure ventilation?
What happens to venous return and cardiac output during positive-pressure ventilation?
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Why might hypotension occur after initiating positive-pressure ventilation?
Why might hypotension occur after initiating positive-pressure ventilation?
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What are the two main reasons for initiating ventilatory support?
What are the two main reasons for initiating ventilatory support?
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How does positive-pressure ventilation affect intrathoracic pressure compared to spontaneous breathing?
How does positive-pressure ventilation affect intrathoracic pressure compared to spontaneous breathing?
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What are the potential hemodynamic consequences of positive-pressure ventilation?
What are the potential hemodynamic consequences of positive-pressure ventilation?
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What is positive-pressure ventilation?
What is positive-pressure ventilation?
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What is the main advantage of volume-controlled ventilation (VC)?
What is the main advantage of volume-controlled ventilation (VC)?
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What is the main advantage of volume-controlled ventilation (VC)?
What is the main advantage of volume-controlled ventilation (VC)?
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Can A/C and SIMV be used with PC and VC modes?
Can A/C and SIMV be used with PC and VC modes?
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What are the initial pressure settings for BiPAP?
What are the initial pressure settings for BiPAP?
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What could low ventilation pressures combined with hypoxia suggest?
What could low ventilation pressures combined with hypoxia suggest?
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What scoring system is recommended for managing sedation in mechanically ventilated patients?
What scoring system is recommended for managing sedation in mechanically ventilated patients?
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What is the target RASS score for sedation?
What is the target RASS score for sedation?
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Why should prolonged neuromuscular blockade be avoided?
Why should prolonged neuromuscular blockade be avoided?
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Volume-controlled ventilation (VC)
Volume-controlled ventilation (VC)
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What key benefit does VC offer?
What key benefit does VC offer?
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What is a potential risk of using VC?
What is a potential risk of using VC?
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When is VC particularly useful?
When is VC particularly useful?
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Pressure-controlled ventilation (PC)
Pressure-controlled ventilation (PC)
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What is a key advantage of PC?
What is a key advantage of PC?
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When is PC particularly beneficial?
When is PC particularly beneficial?
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What is a limitation of PC?
What is a limitation of PC?
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Assist-control ventilation (A/C)
Assist-control ventilation (A/C)
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Intermittent mandatory ventilation (IMV)
Intermittent mandatory ventilation (IMV)
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Continuous spontaneous ventilation (CSV)
Continuous spontaneous ventilation (CSV)
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What is the key difference between A/C and IMV?
What is the key difference between A/C and IMV?
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Dual-control ventilation
Dual-control ventilation
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What is the 'control variable' in mechanical ventilation?
What is the 'control variable' in mechanical ventilation?
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How does spontaneous breathing create airflow?
How does spontaneous breathing create airflow?
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How does positive-pressure ventilation differ from spontaneous breathing?
How does positive-pressure ventilation differ from spontaneous breathing?
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What are the cardiovascular effects of positive pressure ventilation?
What are the cardiovascular effects of positive pressure ventilation?
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When is VC the preferred ventilation mode?
When is VC the preferred ventilation mode?
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When is PC the preferred ventilation mode?
When is PC the preferred ventilation mode?
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What risk does VC pose in patients with impaired lung compliance?
What risk does VC pose in patients with impaired lung compliance?
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What risk does PC pose in patients with acute changes in lung compliance?
What risk does PC pose in patients with acute changes in lung compliance?
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What conditions are better managed with VC?
What conditions are better managed with VC?
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What conditions are better managed with PC?
What conditions are better managed with PC?
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What are some main types of ventilation modes?
What are some main types of ventilation modes?
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What is volume-controlled ventilation (VC)?
What is volume-controlled ventilation (VC)?
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What's the main advantage of VC?
What's the main advantage of VC?
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What is pressure-controlled ventilation (PC)?
What is pressure-controlled ventilation (PC)?
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What are the clinical implications of PC?
What are the clinical implications of PC?
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What are the clinical implications of VC?
What are the clinical implications of VC?
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What is Assist-Control (A/C) ventilation?
What is Assist-Control (A/C) ventilation?
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What is Intermittent Mechanical Ventilation (IMV)?
What is Intermittent Mechanical Ventilation (IMV)?
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What is Continuous Spontaneous Ventilation (CSV)?
What is Continuous Spontaneous Ventilation (CSV)?
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What is tidal volume?
What is tidal volume?
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What is respiratory rate (RR)?
What is respiratory rate (RR)?
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What is inspiratory flow pattern?
What is inspiratory flow pattern?
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What is inspiratory time?
What is inspiratory time?
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What is peak inspiratory pressure (PIP)?
What is peak inspiratory pressure (PIP)?
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What is end-inspiratory alveolar pressure?
What is end-inspiratory alveolar pressure?
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What is pressure-regulated volume control (PRVC)?
What is pressure-regulated volume control (PRVC)?
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What are the limitations of PRVC?
What are the limitations of PRVC?
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What is positive end-expiratory pressure (PEEP)?
What is positive end-expiratory pressure (PEEP)?
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What is inspiratory flow rate?
What is inspiratory flow rate?
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Study Notes
Noninvasive Positive-Pressure Ventilation (NPPV)
- NPPV is the first-line therapy for COPD exacerbations and acute cardiogenic pulmonary edema (ACPE).
- NPPV is generally avoided for definitive management of pneumonia or acute respiratory distress syndrome (ARDS).
- NPPV may still be used in cases of clear improvement or for patients with a do-not-intubate (DNI) status.
BiPAP and CPAP
- Initial BiPAP settings typically include an inspiratory pressure of 10 cm Hâ‚‚O and an expiratory pressure of 5 cm Hâ‚‚O.
- BiPAP uses two levels of pressure (inspiratory and expiratory), while CPAP applies a single, constant pressure.
- BiPAP settings should be frequently evaluated and titrated to maintain patient tolerance.
Pressure-Controlled (PC) vs. Volume-Controlled (VC) Ventilation
- Pressure-controlled ventilation delivers breaths at a predetermined pressure, resulting in variable volumes.
- Volume-controlled ventilation delivers breaths with a predetermined volume, resulting in variable pressures.
- Volume-controlled ventilation ensures consistent tidal volumes, important for patients with specific ventilation needs.
Ventilation Modes
- Assist-Control ventilation delivers a set number and volume of breaths per minute.
- Synchronized Intermittent Mandatory Ventilation (SIMV) synchronizes mandatory breaths with spontaneous breaths, unlike A/C's fixed breath delivery.
- Both A/C and SIMV can be used with either pressure-controlled or volume-controlled ventilation.
Monitoring and Complications
- The recommended maximum plateau pressure during mechanical ventilation is below 30 cm Hâ‚‚O.
- Elevated ventilation pressures may indicate issues like circuit obstructions, bronchospasm, incorrect intubation, or reduced chest wall compliance.
- Low ventilation pressures accompanied by hypoxia might signify a leak in the ventilator circuit, faulty connections, or an esophageal intubation.
Sedation and Analgesia
- The Richmond Agitation-Sedation Scale (RASS) is the recommended tool for managing sedation in intubated patients.
- The target RASS score for sedation is between -2 and 0.
- Prolonged neuromuscular blockade should be avoided due to potential muscle weakness and prolonged recovery time.
Physiology of Positive-Pressure Breathing
- Spontaneous breathing generates negative intrathoracic pressure via diaphragm and intercostal muscle contraction.
- Positive-pressure ventilation decreases venous return and cardiac output due to increased intrathoracic pressure.
- Hypotension can result from positive pressure ventilation, especially in hypovolemic or vasodilated patients.
- Reduced venous return and cardiac output due to increased intrathoracic pressure, especially in hypovolemic or vasodilated patients.
- Low ventilation pressures combined with hypoxia might suggest ventilator circuit leaks, faulty connections, endotracheal tube cuff leaks, accidental extubation, or esophageal intubation
General Concepts
- Ventilatory support is initiated primarily for respiratory failure and airway protection.
- Positive-pressure ventilation increases intrathoracic pressure, contrary to spontaneous breathing that decreases it.
- Potential hemodynamic consequences of positive pressure ventilation include reduced venous return, decreased cardiac output, and possible hypotension.
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