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ISHD Nitrate Medications Quiz - Generic and Drug Category
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ISHD Nitrate Medications Quiz - Generic and Drug Category

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Questions and Answers

Which type of nitroglycerin has the shortest duration of action?

  • Nitroglycerin ointment 2%
  • Nitroglycerin TL spray
  • Nitroglycerin SL tablet (correct)
  • Nitroglycerin SL powder
  • Which nitrate medication is classified as a long-acting nitrate?

  • Nitroglycerin TL spray
  • Nitroglycerin transdermal patch
  • Nitroglycerin SL powder
  • Isosorbide mononitrate IR/ER tablet (correct)
  • Which medication is not a nitrate, but is commonly used for similar therapeutic effects?

  • Nitroglycerin ER capsule (correct)
  • Nitroglycerin SL tablet
  • Nitroglycerin ointment 2%
  • Isosorbide dinitrate IR/ER tablet
  • Is nitroglycerin ER capsule classified as a short-acting nitrate?

    <p>False</p> Signup and view all the answers

    Isosorbide dinitrate IR/ER tablet is classified as a short-acting nitrate?

    <p>False</p> Signup and view all the answers

    Is nitroglycerin ointment 2% considered a long-acting nitrate?

    <p>True</p> Signup and view all the answers

    Explain the differences between short-acting nitrates and long-acting nitrates in terms of pharmacokinetics and clinical indications.

    <p>Short-acting nitrates have a rapid onset and short duration of action, making them suitable for acute relief of angina. Long-acting nitrates have a slower onset and longer duration of action, providing sustained prophylaxis against angina.</p> Signup and view all the answers

    Discuss the potential drug interactions and adverse effects associated with the use of nitroglycerin and its derivatives.

    <p>Nitroglycerin and its derivatives can interact with medications such as sildenafil, tadalafil, and vardenafil, leading to severe hypotension. Common adverse effects include headache, dizziness, and orthostatic hypotension.</p> Signup and view all the answers

    Compare the mechanisms of action of nitroglycerin and isosorbide mononitrate, and explain how their differences contribute to their clinical use.

    <p>Nitroglycerin is a prodrug that releases nitric oxide, leading to vasodilation. Isosorbide mononitrate is a nitrate vasodilator that directly relaxes vascular smooth muscle. Their differences in bioactivation and mechanism of action influence their clinical use in angina management.</p> Signup and view all the answers

    Match the nitroglycerin formulation with its classification based on duration of action:

    <p>Nitroglycerin SL tablet = Short-Acting Nitrates Nitroglycerin ER capsule = Long-Acting Nitrates Nitroglycerin TL spray = Short-Acting Nitrates Nitroglycerin transdermal patch = Long-Acting Nitrates</p> Signup and view all the answers

    Match the medication with its drug category:

    <p>Isosorbide mononitrate IR/ER tablet = Long-Acting Nitrates Nitroglycerin SL powder = Short-Acting Nitrates Isosorbide dinitrate IR/ER tablet = Long-Acting Nitrates Nitroglycerin ointment 2% = Long-Acting Nitrates</p> Signup and view all the answers

    Match the medication with its formulation:

    <p>Nitroglycerin transdermal patch = Long-Acting Nitrates Nitroglycerin ER capsule = Long-Acting Nitrates Nitroglycerin SL powder = Short-Acting Nitrates Isosorbide dinitrate IR/ER tablet = Long-Acting Nitrates</p> Signup and view all the answers

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