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ISHD Nitrate Medications Quiz - Generic and Drug Category

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ISHD Nitrate Medications Quiz - Generic and Drug Category

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Questions and Answers

Which type of nitroglycerin has the shortest duration of action?

Nitroglycerin ointment 2%
Nitroglycerin TL spray
Nitroglycerin SL tablet (correct)
Nitroglycerin SL powder

Which nitrate medication is classified as a long-acting nitrate?

Nitroglycerin TL spray
Nitroglycerin transdermal patch
Nitroglycerin SL powder
Isosorbide mononitrate IR/ER tablet (correct)

Which medication is not a nitrate, but is commonly used for similar therapeutic effects?

Nitroglycerin ER capsule (correct)
Nitroglycerin SL tablet
Nitroglycerin ointment 2%
Isosorbide dinitrate IR/ER tablet

Is nitroglycerin ER capsule classified as a short-acting nitrate?

False (B) Signup and view all the answers

Isosorbide dinitrate IR/ER tablet is classified as a short-acting nitrate?

False (B) Signup and view all the answers

Is nitroglycerin ointment 2% considered a long-acting nitrate?

True (A) Signup and view all the answers

Explain the differences between short-acting nitrates and long-acting nitrates in terms of pharmacokinetics and clinical indications.

Short-acting nitrates have a rapid onset and short duration of action, making them suitable for acute relief of angina. Long-acting nitrates have a slower onset and longer duration of action, providing sustained prophylaxis against angina. Signup and view all the answers

Discuss the potential drug interactions and adverse effects associated with the use of nitroglycerin and its derivatives.

Nitroglycerin and its derivatives can interact with medications such as sildenafil, tadalafil, and vardenafil, leading to severe hypotension. Common adverse effects include headache, dizziness, and orthostatic hypotension. Signup and view all the answers

Compare the mechanisms of action of nitroglycerin and isosorbide mononitrate, and explain how their differences contribute to their clinical use.

Nitroglycerin is a prodrug that releases nitric oxide, leading to vasodilation. Isosorbide mononitrate is a nitrate vasodilator that directly relaxes vascular smooth muscle. Their differences in bioactivation and mechanism of action influence their clinical use in angina management. Signup and view all the answers

Match the nitroglycerin formulation with its classification based on duration of action:

Nitroglycerin SL tablet = Short-Acting Nitrates Nitroglycerin ER capsule = Long-Acting Nitrates Nitroglycerin TL spray = Short-Acting Nitrates Nitroglycerin transdermal patch = Long-Acting Nitrates Signup and view all the answers

Match the medication with its drug category:

Isosorbide mononitrate IR/ER tablet = Long-Acting Nitrates Nitroglycerin SL powder = Short-Acting Nitrates Isosorbide dinitrate IR/ER tablet = Long-Acting Nitrates Nitroglycerin ointment 2% = Long-Acting Nitrates Signup and view all the answers

Match the medication with its formulation:

Nitroglycerin transdermal patch = Long-Acting Nitrates Nitroglycerin ER capsule = Long-Acting Nitrates Nitroglycerin SL powder = Short-Acting Nitrates Isosorbide dinitrate IR/ER tablet = Long-Acting Nitrates Signup and view all the answers