Questions and Answers
What is the action of Nitroglycerin?
Dilates arteries and veins, decreases preload on heart; dilates coronary arteries, increases O2 supply to heart.
What is the use of Nitroglycerin?
Prophylaxis and treatment of acute angina attacks.
Which of the following are common adverse drug reactions (ADRs) of Nitroglycerin? (Select all that apply)
Which of the following can interact with Nitroglycerin to lower blood pressure? (Select all that apply)
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How can Nitroglycerin be administered?
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Study Notes
Action of Nitroglycerin
- Dilates both arteries and veins, leading to decreased preload on the heart.
- Increases blood flow to the heart by dilating coronary arteries, enhancing oxygen supply.
Use of Nitroglycerin
- Primarily used for prophylaxis and treatment of acute angina attacks.
Common ADR (Adverse Drug Reactions) of Nitroglycerin
- Can cause excessive hypotension, dizziness, flushing, and syncope (loss of consciousness).
- May lead to prolonged headaches as a side effect.
- Continuous use can result in tolerance; an 8-12 hour drug-free period is recommended daily.
- Possible rebound hypertension and increased cardiac excitation upon discontinuation.
Drug Interactions for Nitroglycerin
- Interactions with erectile dysfunction drugs, alcohol, calcium channel blockers, and beta-blockers can significantly lower blood pressure.
Administration for Nitroglycerin
- Hospitalized patients are allowed to keep nitroglycerin at their bedside for easy access.
- Available formulations include sustained release tablets, translingual spray, sublingual tablets, topical applications, and IV for acute care.
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Description
Test your knowledge of Nitroglycerin, a nitrate used in managing angina. This quiz includes key actions, uses, and adverse reactions associated with the medication. Perfect for students and healthcare professionals looking to deepen their understanding of this important drug.
