Nitrate Tolerance and Nitroglycerin Patches
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Questions and Answers

Which effect of β-blockers makes them the drugs of choice to treat effort-induced angina?

  • Decreasing heart rate and contractility (correct)
  • Reducing cardiac output and blood pressure
  • Lowering the rate of contraction of the heart
  • Lowering the force of contraction of the heart

    • Why are β-blockers ineffective against vasospastic angina?

  • They reduce cardiac output and blood pressure
  • They are nonselective at high doses and can inhibit β2 receptors (correct)
  • They increase heart rate and contractility
  • They suppress the activation of the heart

    • Why are agents with intrinsic sympathomimetic activity less effective and should be avoided in angina?

  • They are nonselective at high doses and can inhibit β2 receptors
  • They reduce the work of the heart
  • They are less effective in reducing the frequency and severity of angina attacks (correct)
  • They suppress the activation of the heart

    • What is particularly important to remember in the case of asthmatic patients when using β-blockers?

    <p>They are nonselective at high doses and can inhibit β2 receptors (A)</p> Signup and view all the answers

    Why are β-blockers without intrinsic sympathomimetic activity particularly useful in the treatment of patients with myocardial infarction?

    <p>They have been shown to prolong survival (B)</p> Signup and view all the answers

    Why are metoprolol and atenolol preferred over propranolol for treating effort-induced angina?

    <p>They are cardio-selective (D)</p> Signup and view all the answers

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