Neutrophils
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Questions and Answers

Which type of granules in neutrophils contain proteinases, acid phosphatase, myeloperoxidase, and β-glucuronidase?

  • Toxic granulation
  • Specific granules
  • Azurophilic granules (correct)
  • Döhle bodies

What causes neutrophilia and changes in neutrophil morphology?

  • Myelofibrosis, metastasis
  • Inflammation, CML
  • Vitamin B12/folate deficiency
  • Bacterial infection (correct)

What is the term used to describe the presence of neutrophil precursors like band cells and metamyelocytes in peripheral blood?

  • Döhle bodies
  • Left shift (correct)
  • Toxic granulation
  • Leukoerythroblastic reaction

What is the term used to describe the dark blue, coarse granules seen in neutrophils?

<p>Toxic granulation (B)</p> Signup and view all the answers

What is the term used to describe the light blue, peripheral inclusions seen in neutrophils?

<p>Döhle bodies (C)</p> Signup and view all the answers

Which of the following is NOT a neutrophil chemotactic agent?

<p>C6 (D)</p> Signup and view all the answers

What is the term used to describe neutrophils with a nucleus that has 6+ lobes?

<p>Hypersegmented neutrophils (C)</p> Signup and view all the answers

What does a left shift in peripheral blood suggest?

<p>Inflammation, CML (D)</p> Signup and view all the answers

What does a leukoerythroblastic reaction suggest?

<p>Bone marrow infiltration (C)</p> Signup and view all the answers

Which of the following is the primary source of energy for erythrocytes?

<p>Carbohydrate (C)</p> Signup and view all the answers

What is the average lifespan of erythrocytes in healthy adults?

<p>90-120 days (A)</p> Signup and view all the answers

What is the term used to describe the condition of having an increased RBCs?

<p>Erythrocytosis (A)</p> Signup and view all the answers

What does the presence of varying shapes of erythrocytes indicate?

<p>Poikilocytosis (C)</p> Signup and view all the answers

Which of the following is true about thrombocytes (platelets)?

<p>They have a life span of 8-10 days. (C)</p> Signup and view all the answers

Which of the following is a function of thrombocytes (platelets)?

<p>Form platelet plug. (B)</p> Signup and view all the answers

Where is approximately 1/3 of the platelet pool stored?

<p>Spleen (B)</p> Signup and view all the answers

Which receptor is responsible for vWF binding on thrombocytes (platelets)?

<p>GpIb (D)</p> Signup and view all the answers

Which of the following is a component of thrombocytes (platelets) alpha granules?

<p>vWF (B)</p> Signup and view all the answers

Which of the following is a characteristic of monocytes?

<p>Extensive cytoplasm (B)</p> Signup and view all the answers

Where do monocytes differentiate into macrophages?

<p>In the tissues (D)</p> Signup and view all the answers

What does the term 'mono' in monocytes refer to?

<p>One nucleus (A)</p> Signup and view all the answers

Which of the following is true about macrophages?

<p>They differentiate from circulating blood monocytes (D)</p> Signup and view all the answers

Which of the following is a function of macrophages?

<p>Presenting antigens via MHC II (B)</p> Signup and view all the answers

Where are macrophages an important cellular component?

<p>Liver (A)</p> Signup and view all the answers

What initiates septic shock by binding to macrophages?

<p>Lipid A from bacterial LPS (B)</p> Signup and view all the answers

Which molecule from bacterial LPS binds to CD14 on macrophages?

<p>Lipid A (D)</p> Signup and view all the answers

What is the role of CD14 in the initiation of septic shock?

<p>It binds to Lipid A on macrophages (A)</p> Signup and view all the answers

Which immune cells are primarily targeted by Lipid A from bacterial LPS?

<p>Macrophages (C)</p> Signup and view all the answers

Which cells function as a link between the innate and adaptive immune systems?

<p>Dendritic cells (D)</p> Signup and view all the answers

Which receptors are expressed on the surface of dendritic cells?

<p>MHC class II and Fc receptors (D)</p> Signup and view all the answers

What is the term used to describe the presentation of exogenous antigens on MHC class I by dendritic cells?

<p>Cross-presentation (B)</p> Signup and view all the answers

Which of the following is a function of eosinophils?

<p>Phagocytosis of antigen-antibody complexes (C)</p> Signup and view all the answers

What is the major basic protein (MBP) produced by eosinophils?

<p>Eosinophil-derived neurotoxin (D)</p> Signup and view all the answers

What is the cause of eosinophilia known as PACMAN Eats?

<p>Myeloproliferative disorders (C)</p> Signup and view all the answers

What does eosinophilic granulomatosis with polyangiitis cause?

<p>Eosinophilia (A)</p> Signup and view all the answers

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