Podcast
Questions and Answers
Which neurotransmitter is known to be the major inhibitory neurotransmitter?
Which neurotransmitter is known to be the major inhibitory neurotransmitter?
- Gamma-aminobutyric acid (GABA) (correct)
- Glutamate
- Dopamine
- Acetylcholine
What is the enzyme responsible for breaking down acetylcholine into acetate and choline?
What is the enzyme responsible for breaking down acetylcholine into acetate and choline?
- Glutamate decarboxylase
- GAD
- Synthetase
- Acetylcholinesterase (correct)
What is the main mechanism for the rapid removal of neurotransmitters from the synaptic cleft?
What is the main mechanism for the rapid removal of neurotransmitters from the synaptic cleft?
- Re-uptake by postsynaptic neuron
- Diffusion into the postsynaptic neuron
- Enzymatic breakdown by GAD
- Diffusion away from synapses (correct)
Which neurotransmitter is known to be excitatory and the most abundant in the human brain?
Which neurotransmitter is known to be excitatory and the most abundant in the human brain?
What is the ionized form of glutamic acid that serves as an excitatory neurotransmitter?
What is the ionized form of glutamic acid that serves as an excitatory neurotransmitter?
Which neurotransmitter cannot cross the blood-brain barrier?
Which neurotransmitter cannot cross the blood-brain barrier?
Which enzyme synthesizes GABA from glutamate?
Which enzyme synthesizes GABA from glutamate?
What type of receptors involve ligand-gated ion channels and cause a quick depolarization response?
What type of receptors involve ligand-gated ion channels and cause a quick depolarization response?
What effect does GABA have on the postsynaptic neuron?
What effect does GABA have on the postsynaptic neuron?
Which type of receptors are slower due to a signalling cascade?
Which type of receptors are slower due to a signalling cascade?
Where are the somatosensory neurons located in the spinal cord?
Where are the somatosensory neurons located in the spinal cord?
What effect does an antagonist have on neurotransmission?
What effect does an antagonist have on neurotransmission?
How does releasing glutamate in different parts of the brain affect its function?
How does releasing glutamate in different parts of the brain affect its function?
What is the primary function of grey matter in the spinal cord?
What is the primary function of grey matter in the spinal cord?
Which type of receptors can activate many different subtypes?
Which type of receptors can activate many different subtypes?
How does an agonist affect a receptor?
How does an agonist affect a receptor?
Which part of the CNS is highly organised based on innervation of body areas?
Which part of the CNS is highly organised based on innervation of body areas?
How can releasing glutamate in different parts of the brain affect its function?
How can releasing glutamate in different parts of the brain affect its function?
Explain the difference between agonists and antagonists in terms of their effects on neurotransmission.
Explain the difference between agonists and antagonists in terms of their effects on neurotransmission.
What is the significance of allosteric sites in receptor pharmacology?
What is the significance of allosteric sites in receptor pharmacology?
Describe the organization of the grey and white matter in the spinal cord.
Describe the organization of the grey and white matter in the spinal cord.
How does the CNS organize its functions based on the areas of the body that they innervate?
How does the CNS organize its functions based on the areas of the body that they innervate?
Metabotropic GPCR's are faster than ionotropic receptors due to their signalling cascade.
Metabotropic GPCR's are faster than ionotropic receptors due to their signalling cascade.
One neurotransmitter can only activate one subtype of receptor in the brain.
One neurotransmitter can only activate one subtype of receptor in the brain.
Grey matter in the spinal cord contains somatosensory neurons in the ventral horn.
Grey matter in the spinal cord contains somatosensory neurons in the ventral horn.
Agonists bind to receptors and cause no change in the neuron transmission.
Agonists bind to receptors and cause no change in the neuron transmission.
Antagonists bind to receptors but have no effect on neuron transmission.
Antagonists bind to receptors but have no effect on neuron transmission.
