Neurotransmitters: Excitatory & Inhibitory

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

Which of the following best describes the action of an agonist?

  • It decreases the production of neurotransmitters.
  • It blocks a receptor site, preventing a response.
  • It inhibits the reuptake of neurotransmitters.
  • It mimics the effect of a neurotransmitter. (correct)

If a drug is classified as an antagonist, what effect does it have on receptors?

  • It prevents neurotransmitters from binding to the receptor. (correct)
  • It accelerates the production of neurotransmitters.
  • It enhances the receptor's sensitivity to neurotransmitters.
  • It mimics the effects of the natural neurotransmitter.

What is the primary action of reuptake inhibitors on neurotransmitters?

  • They increase the degradation of neurotransmitters in the synapse.
  • They convert inhibitory neurotransmitters into excitatory ones.
  • They stimulate the production of more neurotransmitters.
  • They prevent the reabsorption of neurotransmitters, increasing their availability. (correct)

Which of the following neurotransmitters is primarily associated with excitatory effects?

<p>Dopamine (D)</p> Signup and view all the answers

Which of the following neurotransmitters primarily functions as an inhibitory neurotransmitter?

<p>GABA (C)</p> Signup and view all the answers

Which neurotransmitter is known to have both inhibitory and excitatory effects?

<p>Acetylcholine (B)</p> Signup and view all the answers

Which of the following neurotransmitters is associated with mood regulation and is typically inhibitory?

<p>Serotonin (D)</p> Signup and view all the answers

If a drug increases the effect of serotonin, which of the following effects could be expected?

<p>Decreased anxiety and improved mood (D)</p> Signup and view all the answers

Which of the following is an example of a neurotransmitter that primarily causes excitation in the nervous system?

<p>Glutamine (B)</p> Signup and view all the answers

What role do inhibitory neurotransmitters play in neural function?

<p>They reduce the likelihood of an action potential. (C)</p> Signup and view all the answers

How do adrenergic drugs affect the body?

<p>They relax the body. (A)</p> Signup and view all the answers

What is the potential consequence of taking too much benzodiazepine?

<p>Coma (A)</p> Signup and view all the answers

What is the primary effect of opioid analgesics on the central nervous system (CNS)?

<p>Suppression (D)</p> Signup and view all the answers

What is the antidote for Fentanyl?

<p>Naloxone (A)</p> Signup and view all the answers

Which neurotransmitter is released by Cholinergics?

<p>Acetylcholine (D)</p> Signup and view all the answers

What is a potential physiological effect of taking Fentanyl?

<p>Decreased respiration (A)</p> Signup and view all the answers

Which of the following drugs is categorized as a Benzodiazepine, often prescribed to reduce anxiety?

<p>Alprazolam (D)</p> Signup and view all the answers

How does acetaminophen differ from opioid analgesics like fentanyl in terms of anti-inflammatory effects?

<p>Acetaminophen has no anti-inflammatory effects, while fentanyl's anti-inflammatory properties are more potent. (D)</p> Signup and view all the answers

What is the primary therapeutic goal when administering drugs like benzodiazepines for anxiety?

<p>To reduce feelings of fear, danger, and tension (B)</p> Signup and view all the answers

How might excess carbon dioxide levels relate to the administration of strong pain killers like fentanyl?

<p>Fentanyl administration can lead to decreased respiration, causing an increase in carbon dioxide levels. (D)</p> Signup and view all the answers

Which of the following scenarios would warrant a prescription for Levetiracetam?

<p>Treatment of partial-onset seizures. (D)</p> Signup and view all the answers

A patient has been prescribed an SSRI. What is the most important instruction to give this patient regarding their medication?

<p>They should discuss with an HCP prior to discontinuing. (D)</p> Signup and view all the answers

A patient reports difficulty maintaining relationships and exhibits consistently changing behaviors. Which class of disorders might the health care provider suspect?

<p>Mood disorders. (D)</p> Signup and view all the answers

What is a crucial consideration when a patient is prescribed an antiseizure medication such as Phenytoin?

<p>The importance of regular blood tests to monitor drug levels. (D)</p> Signup and view all the answers

How do SSRIs work to alleviate symptoms of depression?

<p>By inhibiting the reuptake of serotonin. (C)</p> Signup and view all the answers

What is a potential consequence of abruptly stopping antidepressant medication?

<p>Rebound insomnia, nausea, and/or anxiety. (D)</p> Signup and view all the answers

What is the primary mechanism of action for drugs like barbiturates and zolpidem in treating insomnia?

<p>Enhancing GABA activity. (C)</p> Signup and view all the answers

What is the therapeutic implication of understanding that 'mood is someone's behavior change constantly'?

<p>It suggests a possible need to further assess mood disorders. (C)</p> Signup and view all the answers

A doctor is considering prescribing medication for a patient experiencing emotional and mood disorders. Which medication requires further consideration?

<p>SSRI (D)</p> Signup and view all the answers

What is the role of GABA in the context of anti-seizure medications?

<p>Inhibiting neuronal excitability. (A)</p> Signup and view all the answers

What is the primary mechanism by which SNRIs affect neurotransmitter levels in the brain?

<p>Blocking the reuptake of serotonin and norepinephrine. (B)</p> Signup and view all the answers

Which combination of medications or substances significantly elevates the risk of serotonin syndrome?

<p>Combining antidepressants with migraine pain medication or herbal remedies. (B)</p> Signup and view all the answers

What are the key signs and symptoms indicative of serotonin syndrome?

<p>Sweating, restlessness, dilated pupils, seizure, elevated blood pressure, and tachycardia. (B)</p> Signup and view all the answers

Why is extreme caution necessary when prescribing MAOIs (Monoamine Oxidase Inhibitors)?

<p>They require strict dietary restrictions due to the risk of hypertensive crisis. (B)</p> Signup and view all the answers

What is the primary therapeutic goal of mood stabilizers, such as lithium, in treating bipolar disorder?

<p>To stabilize mood swings and prevent extreme highs and lows. (C)</p> Signup and view all the answers

Why is it critical for patients taking lithium to avoid table salt (sodium)?

<p>Sodium competes with lithium in the kidneys, affecting lithium levels and potentially causing toxicity. (C)</p> Signup and view all the answers

What potential side effects should a patient be aware of when starting lithium therapy?

<p>Poor coordination, nausea, vomiting, diarrhea, and dehydration. (C)</p> Signup and view all the answers

What is the primary indication for using antipsychotic medications like Haloperidol?

<p>To manage psychosis and diminish abnormal actions and behaviors, such as hallucinations. (D)</p> Signup and view all the answers

How might Haloperidol affect a patient experiencing psychosis?

<p>Decrease the hallucinations and abnormal actions and behavior. (C)</p> Signup and view all the answers

A patient on Haloperidol reports seeing 'shadow people' that no one else can see. How would you describe this symptom?

<p>Visual hallucinations, unique to the patient’s psychotic state. (A)</p> Signup and view all the answers

What is the primary cause of extrapyramidal symptoms?

<p>Blockage of dopamine in the midbrain. (C)</p> Signup and view all the answers

Which of the following is classified as a symptom rather than a disease?

<p>Dementia (B)</p> Signup and view all the answers

What is a critical aspect of managing Carbidopa/Levodopa treatment for Parkinson's disease, especially concerning side effects?

<p>The necessity for consistent monitoring and possible adjustments due to side effects. (A)</p> Signup and view all the answers

When should healthcare providers exercise extreme caution when administering propofol?

<p>When managing and maintaining the patient's airway. (C)</p> Signup and view all the answers

Which of the following indicates how local anesthetics are typically administered?

<p>Topically, via cream, aerosol spray, or otic application (B)</p> Signup and view all the answers

How does Donepezil function in the treatment of Alzheimer's disease?

<p>By increasing the concentration of acetylcholine in the brain. (A)</p> Signup and view all the answers

A patient taking Carbidopa/Levodopa for Parkinson's disease experiences uncontrolled movements and nausea. What adjustment to the medication regimen might be considered?

<p>Temporarily stopping the medication and then restarting at a lower dose. (C)</p> Signup and view all the answers

Which initial symptom might lead a healthcare provider to suspect extrapyramidal syndrome (EPS) in a patient treated with dopamine-blocking agents?

<p>Involuntary muscle movements or rigidity. (D)</p> Signup and view all the answers

Why is it important to use caution when using general anesthesia?

<p>It can affect the patient's airway. (C)</p> Signup and view all the answers

How should topical anesthetics be administered to children for minor procedures requiring skin numbing?

<p>Spray liberally, avoiding contact with eyes or open wounds. (B)</p> Signup and view all the answers

Flashcards

Agonist

Mimics the effects of a neurotransmitter.

Antagonist

Blocks the action of a neurotransmitter by blocking the receptor.

Reuptake Inhibitor

Blocks the reuptake of a neurotransmitter, increasing its availability.

Excitatory Neurotransmitter

Increases the likelihood of a neuron firing.

Signup and view all the flashcards

Inhibitory Neurotransmitter

Decreases the likelihood of a neuron firing.

Signup and view all the flashcards

Dopamine

Excitatory neurotransmitter involved in mood, motivation, and reward.

Signup and view all the flashcards

Serotonin

Inhibitory neurotransmitter that stabilizes mood, and can affect appetite and sleep.

Signup and view all the flashcards

Norepinephrine

Excitatory neurotransmitter increasing alertness, arousal, and attention.

Signup and view all the flashcards

GABA

Inhibitory neurotransmitter primary role is to reduce neuron excitability throughout the nervous system.

Signup and view all the flashcards

Acetylcholine

Neurotransmitter that can be both excitatory and inhibitory depending on the receptor.

Signup and view all the flashcards

Cholinergics

Drugs that release acetylcholine.

Signup and view all the flashcards

Adrenergics

Drugs that relax the body.

Signup and view all the flashcards

Analgesics

Medications used to reduce pain.

Signup and view all the flashcards

Opioid Analgesic

Strong pain killer, suppresses the central nervous system

Signup and view all the flashcards

Fentanyl (IV)

An opioid analgesic administered intravenously.

Signup and view all the flashcards

Naloxone

Medication that serves as an antidote to opioids.

Signup and view all the flashcards

Anxiety

A feeling of fear, danger, and tenseness.

Signup and view all the flashcards

Benzodiazepine

Examples include alprazolam; has a calming effect.

Signup and view all the flashcards

SSRIS

Selective Serotonin Reuptake Inhibitors

Signup and view all the flashcards

Insomnia Medications

Medications used to treat insomnia, such as Barbiturates and Zolpidem.

Signup and view all the flashcards

Antiseizure Medications

Medications used to prevent or control seizures.

Signup and view all the flashcards

GABA and Phenytoin

A neurotransmitter that reduces neuron excitability, and a common antiseizure mediation. (Phenytoin)

Signup and view all the flashcards

Levetiracetam

Levetiracetam: Used for partial onset seizures.

Signup and view all the flashcards

Emotional/Mood Disorders

Behavior exhibits difficulty maintaining relationships

Signup and view all the flashcards

Amphetamine

A stimulant medication. Examples include Amphetamine and Dextroamphetamine .

Signup and view all the flashcards

Antidepressant Discontinuation Syndrome

A syndrome which can occur following the interruption, reduction, or discontinuation of antidepressant drugs.

Signup and view all the flashcards

Rebound Effect

Rebound of insomnia, as well as symptoms of nausea and anxiety.

Signup and view all the flashcards

Discontinuing Medications

It is not safe to abruptly discontinue medication. One should always discuss discontinuing medications with a qualified HCP.

Signup and view all the flashcards

Serotonin Syndrome

Potentially life-threatening condition caused by excessive serotonin activity in the central nervous system.

Signup and view all the flashcards

Monoamine Oxidase Inhibitor

Class of drugs that prevent the breakdown of monoamine neurotransmitters, such as serotonin, norepinephrine, and dopamine.

Signup and view all the flashcards

Mood Stabilizers

Medications used to stabilize mood, particularly in bipolar disorder.

Signup and view all the flashcards

Lithium

A common mood stabilizer that requires regular blood tests.

Signup and view all the flashcards

Antipsychotics

Medications used used to manage psychosis, like hallucinations and delusions

Signup and view all the flashcards

Haloperidol

A traditional antipsychotic medication associated with the management of abnormal actions

Signup and view all the flashcards

Extrapyramidal symptoms

A set of side effects caused by blocking dopamine in the midbrain.

Signup and view all the flashcards

Extrapyramidal symptom examples

Symptoms include: Acute dystonia, Akathisia, drooling, shuffling gait.

Signup and view all the flashcards

Dementia

A symptom characterized by progressive, irreversible decline in mental function.

Signup and view all the flashcards

Alzheimer's

A disease and diagnosis that cause progressive, irreversible decline in mental function.

Signup and view all the flashcards

Parkinson's Disease medications

Carbidopa and Levodopa are medications used, need both medications.

Signup and view all the flashcards

Local Anesthesia

Include cream, aerosol spray and otic.

Signup and view all the flashcards

Propofol

Pay attention to the patient's airway.

Signup and view all the flashcards

General Anesthesia

Medication designed to make a patient unconscious.

Signup and view all the flashcards

Study Notes

  • Extrapyramidal symptoms are a set of manifestations caused by blocking dopamine in the midbrain
  • Symptoms include acute dystonia, akathisia, drooling, and shuffling gait
  • Dementia is a symptom and not a disease
  • A progressive, irreversible decline in mental function is seen
  • Alzheimer's is a disease, or diagnosis
  • Donezopil

Parkinson's Disease

  • Carbidopa/levodopa: both medications are needed
  • A possible side effect is to stop a week and start over

Local Anesthesia

  • Delivered through cream, aerosol spray, or otic application

General Anesthesia

  • Propofol
  • Need to pay attention to the airway
  • SNRIs block reuptake of serotonin
  • Serotonin syndrome can occur when mixing antidepressants with migraine pain medication or herbal medications
  • Serotonin syndrome symptoms: sweating, restlessness, dilated pupils, seizure, changes in blood pressure (BP), and tachycardia
  • Monoamine oxidase inhibitors cannot be taken with other medications; they interact

Mood Stabilizers

  • Mood stabilizers stabilize mood, for example, in bipolar disorder; lithium is an example of a mood stabilizer
  • Avoid table salt while taking mood stabilizers; can be fatal, regular blood tests are needed
  • Side effects of mood stabilizers: poor coordination, nausea, vomiting, diarrhea, dehydration, and overdose

Antipsychotics

  • Haloperidol can treat abnormal actions and behavior
  • Some experience situations that only they can see or hear

Studying That Suits You

Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

Quiz Team

More Like This

Use Quizgecko on...
Browser
Browser