Neurotransmitters and Antidepressants

What is the mechanism of action of Monoamine Oxidase Inhibitors (MAOIs)?

Activate the neurotransmitters
Inhibit the activity of Monoamine Oxidase enzyme (correct)
Inhibit the reuptake of neurotransmitters
Increase the breakdown of neurotransmitters

What is a therapeutic use of Monoamine Oxidase Inhibitors (MAOIs)?

To reduce pain (correct)
To treat Parkinson's disease
To manage Hypertension
To induce anesthesia

What is a common adverse reaction of Monoamine Oxidase Inhibitors (MAOIs)?

Diarrhea
Tremors
Orthostatic hypotension (correct)
Anxiety

What is the reference book for the information about Monoamine Oxidase Inhibitors (MAOIs)?

Core Concepts in Pharmacology (A) Signup and view all the answers

What is not a therapeutic use of Monoamine Oxidase Inhibitors (MAOIs)?

To treat cancer (D) Signup and view all the answers

What is the primary effect of benzodiazepines on chloride channels?

Keeping the chloride channel open for a prolonged period (D) Signup and view all the answers

What is the primary difference between the mechanism of action of barbiturates and benzodiazepines?

Barbiturates decrease the duration of chloride channel opening, while benzodiazepines increase the duration of chloride channel opening (A) Signup and view all the answers

What is the mechanism of action of non-benzodiazepine anxiolytics?

Blocking the receptors for dopamine and serotonin (B) Signup and view all the answers

What is a common therapeutic use of benzodiazepines?

Treatment of anxiety disorders (D) Signup and view all the answers

What is a potential adverse effect of benzodiazepine use?

Fatigue (D) Signup and view all the answers

What is the primary mechanism of action of anticholinergic drugs in treating parkinsonism?

Decrease the production of acetylcholine (C) Signup and view all the answers

What is the primary therapeutic use of dopaminergic drugs?

To treat signs and symptoms of parkinsonism (D) Signup and view all the answers

What is the effect of anesthesia on nerve impulse transmission?

Temporarily inhibit nerve impulse transmission (B) Signup and view all the answers

What is the primary difference between local and general anesthesia?

The area of the body affected (A) Signup and view all the answers

What is a common adverse reaction of dopaminergic and anticholinergic drugs?

Nausea and vomiting (B) Signup and view all the answers

What is the primary mechanism of action of benzodiazepines?

Increase the effect of GABA (C) Signup and view all the answers

What is the main difference between the mechanism of action of barbiturates and benzodiazepines?

Barbiturates open chloride channels for a short period while benzodiazepines open them for a long period (B) Signup and view all the answers

What is the primary therapeutic use of barbiturates?

To treat insomnia and prepare patients for surgery (C) Signup and view all the answers

What is the main difference between benzodiazepines and non-benzodiazepines?

Benzodiazepines are a class of anti-anxiety drugs while non-benzodiazepines are not (B) Signup and view all the answers

What is the common effect of barbiturates on the respiratory system?

Respiratory depression (A) Signup and view all the answers

What is the primary mechanism of action of Tricyclic Antidepressants (TCAs)?

Inhibiting the uptake of norepinephrine and serotonin into the same neuron (C) Signup and view all the answers

Which type of antidepressant selectively inhibits the uptake of serotonin into the same neuron?

Selective Serotonin Reuptake Inhibitors (SSRIs) (C) Signup and view all the answers

What is the effect of some antidepressants on the central nervous system?

It causes CNS stimulation (C) Signup and view all the answers

What is the effect of some antidepressants on neurotransmitters?

They block the reuptake of neurotransmitters (A) Signup and view all the answers

What is the result of blocking the reuptake of neurotransmitters by antidepressants?

The patient will become excited and relieved from depression (C) Signup and view all the answers

What is the primary effect of GABA on impulse transmission?

Slow down or inhibit impulse transmission (A) Signup and view all the answers

What is the difference between barbiturates and benzodiazepines in terms of their mechanism of action?

Barbiturates have a different binding site on the GABA receptor than benzodiazepines (D) Signup and view all the answers

What is the primary therapeutic use of sedatives and hypnotics?

To produce a calming and relaxing effect (D) Signup and view all the answers

Which of the following is a characteristic of barbiturates that is NOT shared with benzodiazepines?

Increased duration of chloride channel opening (A) Signup and view all the answers

What is the effect of barbiturates on the central nervous system?

Depression of the CNS (C) Signup and view all the answers

What is the primary mechanism of action of antiepileptic drugs?

Reduce the excitability of neurons in the brain (A) Signup and view all the answers

What is a common symptom of Parkinson's disease?

Muscular rigidity (C) Signup and view all the answers

What is the primary cause of Parkinson's disease?

Deficiency of dopamine and excess of acetylcholine in the CNS (B) Signup and view all the answers

What is the therapeutic use of antiepileptic drugs?

To relieve seizures (D) Signup and view all the answers

What is a possible adverse reaction of antiepileptic drugs?

Constipation and hepatotoxicity (B) Signup and view all the answers

What is a characteristic of epilepsy?

It is a permanent seizure disorder (D) Signup and view all the answers

What is the primary effect of antiepileptic drugs on neurons?

Decrease the excitability of neurons (D) Signup and view all the answers

What is a symptom of epilepsy?

Seizure (C) Signup and view all the answers

What is the primary cause of seizures in epilepsy?

Abnormal electrical activity in the brain (B) Signup and view all the answers

What is a possible therapeutic use of anti-parkinsonism drugs?

To relieve tremors (A) Signup and view all the answers