10 Questions
What is the effect of noradrenergic and serotonergic antidepressants on the reuptake of neurotransmitters?
They inhibit the reuptake of norepinephrine and serotonin
What is the primary use of tricyclic antidepressants like amitriptyline and doxepin?
Treatment of neuropathic pain
What neurotransmitters are released by local inhibitory interneurons?
GABA and glycine
What is the mechanism of action of tricyclic antidepressants in the treatment of neuropathic pain?
They inhibit the reuptake of norepinephrine and serotonin
What is a common application of imipramine?
Treatment of depression
What is the primary function of local inhibitory interneurons?
Release of GABA and glycine
Which neurotransmitters are involved in the mechanism of action of tricyclic antidepressants?
Norepinephrine and serotonin
What is the common application of amitriptyline and doxepin?
Treatment of neuropathic pain
What is the effect of tricyclic antidepressants on the reuptake of neurotransmitters?
Inhibition of reuptake
What is a characteristic of tricyclic antidepressants?
Inhibitors of norepinephrine and serotonin reuptake
Study Notes
Noradrenergic and Serotonergic Antidepressants
- Tricyclic antidepressants are used to treat neuropathic pain.
- Examples of tricyclic antidepressants include amitriptyline, doxepin, and imipramine.
- These antidepressants work by inhibiting the reuptake of norepinephrine and serotonin.
Local Inhibitory Interneurons
- Local inhibitory interneurons release GABA (gamma-aminobutyric acid) and glycine.
- GABA and glycine are involved in inhibitory functions in the nervous system.
Noradrenergic and Serotonergic Antidepressants
- Tricyclic antidepressants are used to treat neuropathic pain.
- Examples of tricyclic antidepressants include amitriptyline, doxepin, and imipramine.
- These antidepressants work by inhibiting the reuptake of norepinephrine and serotonin.
Local Inhibitory Interneurons
- Local inhibitory interneurons release GABA (gamma-aminobutyric acid) and glycine.
- GABA and glycine are involved in inhibitory functions in the nervous system.
This quiz covers the treatment of neuropathic pain using tricyclic antidepressants such as amitriptyline, doxepin, and imipramine, and their effects on local inhibitory interneurons. Learn about the role of norepinephrine, serotonin, GABA, and glycine in pain management.
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