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Noradrenergic and Serotonergic Antidepressants

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Noradrenergic and Serotonergic Antidepressants

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Questions and Answers

What is the effect of noradrenergic and serotonergic antidepressants on the reuptake of neurotransmitters?

They stimulate the release of GABA and glycine

They inhibit the reuptake of norepinephrine and serotonin (correct)

They enhance the reuptake of norepinephrine and serotonin

They have no effect on the reuptake of norepinephrine and serotonin

What is the primary use of tricyclic antidepressants like amitriptyline and doxepin?

Treatment of depression

Treatment of bipolar disorder

Treatment of anxiety disorders

Treatment of neuropathic pain (correct)

What neurotransmitters are released by local inhibitory interneurons?

Dopamine and acetylcholine

GABA and glycine (correct)

Norepinephrine and serotonin

GABA and glutamate

What is the mechanism of action of tricyclic antidepressants in the treatment of neuropathic pain?

They inhibit the reuptake of norepinephrine and serotonin Signup and view all the answers

What is a common application of imipramine?

Treatment of depression Signup and view all the answers

What is the primary function of local inhibitory interneurons?

Release of GABA and glycine Signup and view all the answers

Which neurotransmitters are involved in the mechanism of action of tricyclic antidepressants?

Norepinephrine and serotonin Signup and view all the answers

What is the common application of amitriptyline and doxepin?

Treatment of neuropathic pain Signup and view all the answers

What is the effect of tricyclic antidepressants on the reuptake of neurotransmitters?

Inhibition of reuptake Signup and view all the answers

What is a characteristic of tricyclic antidepressants?

Inhibitors of norepinephrine and serotonin reuptake Signup and view all the answers

Study Notes

Noradrenergic and Serotonergic Antidepressants

Tricyclic antidepressants are used to treat neuropathic pain.
Examples of tricyclic antidepressants include amitriptyline, doxepin, and imipramine.
These antidepressants work by inhibiting the reuptake of norepinephrine and serotonin.

Local Inhibitory Interneurons

Local inhibitory interneurons release GABA (gamma-aminobutyric acid) and glycine.
GABA and glycine are involved in inhibitory functions in the nervous system.

Noradrenergic and Serotonergic Antidepressants

Tricyclic antidepressants are used to treat neuropathic pain.
Examples of tricyclic antidepressants include amitriptyline, doxepin, and imipramine.
These antidepressants work by inhibiting the reuptake of norepinephrine and serotonin.

Local Inhibitory Interneurons

Local inhibitory interneurons release GABA (gamma-aminobutyric acid) and glycine.
GABA and glycine are involved in inhibitory functions in the nervous system.

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Description

This quiz covers the treatment of neuropathic pain using tricyclic antidepressants such as amitriptyline, doxepin, and imipramine, and their effects on local inhibitory interneurons. Learn about the role of norepinephrine, serotonin, GABA, and glycine in pain management.