Neurotransmitter Activity and Calcium Channel Inhibition Quiz

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10 Questions

Phenobarbital does not interact with the GABAA-Cl channel complex.

False

Primidone inhibits Na/K transport channels in the central nervous system.

False

Primidone directly causes vitamin D deficiency.

False

Primidone is a first-line treatment for essential tremors.

False

Primidone is the drug of choice for treating infantile spasms.

False

Primidone's metabolism can cause folic acid and vitamin B12 deficiency.

True

Ethosuximide, valproate, and trimethadione are used in the treatment of partial and generalized tonic-clonic seizures.

False

Inhibition of slow Ca2+ ion current is one of the mechanisms of action for antiseizure drugs.

True

Antiseizure drugs primarily target excitatory neurotransmitter activity in the CNS.

False

Primidone is associated with hematological abnormalities such as leucopenia, thrombocytopenia, and hypoprothrombinemia in newborns.

True

Test your knowledge on excitatory neurotransmitter activity in the CNS, including glutamate and aspartate, as well as the inhibition of Ca2+ channels. Learn about the mechanisms of action of valproate and topiramate on NMDA and kainate receptors. Challenge yourself with questions on metabotropic and ionotropic receptors.

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