10 Questions
Phenobarbital does not interact with the GABAA-Cl channel complex.
False
Primidone inhibits Na/K transport channels in the central nervous system.
False
Primidone directly causes vitamin D deficiency.
False
Primidone is a first-line treatment for essential tremors.
False
Primidone is the drug of choice for treating infantile spasms.
False
Primidone's metabolism can cause folic acid and vitamin B12 deficiency.
True
Ethosuximide, valproate, and trimethadione are used in the treatment of partial and generalized tonic-clonic seizures.
False
Inhibition of slow Ca2+ ion current is one of the mechanisms of action for antiseizure drugs.
True
Antiseizure drugs primarily target excitatory neurotransmitter activity in the CNS.
False
Primidone is associated with hematological abnormalities such as leucopenia, thrombocytopenia, and hypoprothrombinemia in newborns.
True
Test your knowledge on excitatory neurotransmitter activity in the CNS, including glutamate and aspartate, as well as the inhibition of Ca2+ channels. Learn about the mechanisms of action of valproate and topiramate on NMDA and kainate receptors. Challenge yourself with questions on metabotropic and ionotropic receptors.
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