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Questions and Answers
Phenobarbital does not interact with the GABAA-Cl channel complex.
False
Primidone inhibits Na/K transport channels in the central nervous system.
False
Primidone directly causes vitamin D deficiency.
False
Primidone is a first-line treatment for essential tremors.
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Primidone is the drug of choice for treating infantile spasms.
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Primidone's metabolism can cause folic acid and vitamin B12 deficiency.
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Ethosuximide, valproate, and trimethadione are used in the treatment of partial and generalized tonic-clonic seizures.
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Inhibition of slow Ca2+ ion current is one of the mechanisms of action for antiseizure drugs.
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Antiseizure drugs primarily target excitatory neurotransmitter activity in the CNS.
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Primidone is associated with hematological abnormalities such as leucopenia, thrombocytopenia, and hypoprothrombinemia in newborns.
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