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Questions and Answers
What is the primary effect of the increased intracellular calcium ion concentration in the axon terminal?
What is the primary effect of the increased intracellular calcium ion concentration in the axon terminal?
- Depolarization of the motor end plate
- Hydrolysis of Ach by the cholinesterase enzyme
- Migration of synaptic vesicles towards the membrane and fusion with it (correct)
- Opening of membrane channels to both Na and K ions
What is the primary function of the cholinesterase enzyme in the synaptic cleft?
What is the primary function of the cholinesterase enzyme in the synaptic cleft?
- To depolarize the motor end plate
- To bind to the receptor sites on the postsynaptic membrane
- To facilitate the release of Ach from the synaptic vesicles
- To rapidly hydrolyze Ach into choline and acetic acid (correct)
What is the result of the influx of Na ions and efflux of K ions at the postsynaptic membrane?
What is the result of the influx of Na ions and efflux of K ions at the postsynaptic membrane?
- Generation of an action potential on the presynaptic membrane
- Local hyperpolarization of the motor end plate
- No change in the membrane potential of the motor end plate
- Local depolarization of the motor end plate (correct)
What is the role of the voltage-gated Ca channels in the axon terminal?
What is the role of the voltage-gated Ca channels in the axon terminal?
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What is the direction of the movement of the synaptic vesicles in the axon terminal?
What is the direction of the movement of the synaptic vesicles in the axon terminal?
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What is the consequence of the action potential propagating on both sides of the motor end plate?
What is the consequence of the action potential propagating on both sides of the motor end plate?
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What is the binding site of Ach on the postsynaptic membrane?
What is the binding site of Ach on the postsynaptic membrane?
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