Neurotransmission: Autonomic and Somatic Systems
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Questions and Answers

Which of the following substances is classified as a sympathetic neurotransmitter?

  • Dopamine
  • Acetylcholine
  • Sympathin (correct)
  • Muscarine
  • What key concept did Dixon propose regarding the vagus nerve in 1907?

  • It acts solely as an inhibitor of nerve impulses.
  • It primarily affects the sympathetic nervous system.
  • It liberated a muscarine-like chemical. (correct)
  • It released a substance acting as a stimulant.
  • What did Barger and Dale identify about the effects of sympathetic nerve stimulation?

  • They primarily depend on the presence of sympathin.
  • They lack similarity with any known chemical substances.
  • They resemble the effects of sympathomimetic primary amines. (correct)
  • They are most closely reproduced by secondary amines.
  • In the context of neurotransmitters, which of the following actions was NOT noted by Dale regarding acetylcholine?

    <p>It acts similarly to EPI. (B)</p> Signup and view all the answers

    What did Reid Hunt investigate in 1910 regarding neurotransmitters?

    <p>The actions of acetylcholine and other choline esters. (B)</p> Signup and view all the answers

    Which mechanism is primarily responsible for the action of antiepileptic drugs?

    <p>Alteration of ion channel activity (B)</p> Signup and view all the answers

    What is a common side effect associated with benzodiazepines?

    <p>Sedation and cognitive impairment (A)</p> Signup and view all the answers

    Which class of antidepressants primarily works by inhibiting the reuptake of serotonin?

    <p>Selective serotonin reuptake inhibitors (C)</p> Signup and view all the answers

    Which condition is a contraindication for benzodiazepine usage?

    <p>Severe respiratory disorders (D)</p> Signup and view all the answers

    What is a potential risk associated with the long-term use of antiepileptic drugs?

    <p>Development of drug resistance (A)</p> Signup and view all the answers

    Which neurotransmitter's activity is primarily targeted by the pharmacotherapy of anxiety disorders?

    <p>GABA (D)</p> Signup and view all the answers

    Which of the following best describes a common action of mood stabilizers in bipolar disorder treatment?

    <p>Modification of glutamate release (C)</p> Signup and view all the answers

    What is a notable withdrawal symptom associated with benzodiazepines?

    <p>Severe insomnia (D)</p> Signup and view all the answers

    Which neurotransmitter is primarily associated with the action of benzodiazepines?

    <p>GABA (D)</p> Signup and view all the answers

    What is the primary mechanism of action for most anti-depressants?

    <p>Inhibiting serotonin reuptake (D)</p> Signup and view all the answers

    Which of the following divisions of the autonomic nervous system is activated during a stress response?

    <p>Sympathetic outflow (A)</p> Signup and view all the answers

    5-HT, a neurotransmitter involved in mood regulation, is also known as what?

    <p>Serotonin (D)</p> Signup and view all the answers

    Which type of receptor is predominantly involved in the actions of anti-epileptics?

    <p>Ligand-gated ion channels (D)</p> Signup and view all the answers

    Which cranial nerve is part of the parasympathetic division responsible for innervating the heart?

    <p>Cranial nerve X (A)</p> Signup and view all the answers

    What role does inositol 1,4,5-trisphosphate (IP3) play in neurotransmitter signaling?

    <p>Second messenger in signal transduction (D)</p> Signup and view all the answers

    Which condition is commonly treated with benzodiazepines due to their sedative properties?

    <p>Anxiety disorders (C)</p> Signup and view all the answers

    Which of the following terms refers to the inhibitory postsynaptic potential?

    <p>IPSP (A)</p> Signup and view all the answers

    Which of the following neurotransmitters is primarily associated with the sympathetic functions integrated by the midline nuclei?

    <p>Epinephrine (B)</p> Signup and view all the answers

    What role do interstitial cells of Cajal (ICC) play in the enteric nervous system?

    <p>They act as the primary pacemakers in gastrointestinal motility. (B)</p> Signup and view all the answers

    At which level are higher integrated patterns of response generally organized?

    <p>Hypothalamic level (C)</p> Signup and view all the answers

    Which of the following is NOT a characteristic of the extraneuronal transporter (ENT)?

    <p>It has no relevance in sympathetic nervous system functions. (A)</p> Signup and view all the answers

    What is the primary function of excitatory postsynaptic potentials (EPSP) within the central nervous system?

    <p>They depolarize the postsynaptic neuron, leading to an action potential. (C)</p> Signup and view all the answers

    What is the role of the tuber cinereum in autonomic function?

    <p>It integrates and regulates autonomic, endocrine, and behavioral responses. (B)</p> Signup and view all the answers

    Which component is least likely to be directly involved in the patterned responses organized by the brainstem?

    <p>Emotional regulation (C)</p> Signup and view all the answers

    In which context would dihydroxyphenylglycolaldehyde (DOPGAL) likely be significant?

    <p>In the regulation of enteric nervous system functions (B)</p> Signup and view all the answers

    Which level of the nervous system is involved in organizing more limited responses as compared to the hypothalamic level?

    <p>Spinal cord (C)</p> Signup and view all the answers

    Which neurotransmitter could potentially influence both autonomic and behavioral responses through its integration at the hypothalamic level?

    <p>Norepinephrine (D)</p> Signup and view all the answers

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    Study Notes

    Neurotransmission: Autonomic and Somatic Motor Systems

    • Autonomic nervous system has two main divisions: sympathetic (thoracic and lumbar regions) and parasympathetic (cranial nerves III, VII, IX, X, and sacral regions).
    • Effector cells have both excitatory and inhibitory "receptive substances".
    • Epinephrine (EPI) is a chemical mediator released by sympathetic nerves at neuroeffector junctions.
    • Early studies suggested "sympathin" is similar to EPI but not identical.
    • ACh (acetylcholine) and choline esters were identified as chemical transmitters, with actions mimicking muscarinic and nicotinic responses.
    • Neurotransmission involves integration at hypothalamic, basal forebrain, brainstem, and spinal cord levels.
    • Integrated responses involve autonomic, endocrine, and behavioral components.

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    Description

    Explore the intricacies of neurotransmission within the autonomic and somatic motor systems. This quiz covers key concepts like the roles of the sympathetic and parasympathetic divisions, neurotransmitters such as epinephrine and acetylcholine, and their implications on integration across various brain regions. Test your understanding of how these systems interact and impact behavior.

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