Neurosurgery and Cranial Anatomy
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Questions and Answers

What is the main principle of the Monro-Kellie doctrine?

  • The volume of the cranial cavity increases with age
  • The brain tissue, CSF, and blood vessels have a variable volume
  • The cranial cavity has a fixed volume composed of brain tissue, CSF, and blood vessels (correct)
  • The intravascular blood is the largest component of the cranial cavity

What is the rate of cerebrospinal fluid production?

  • 10 to 15 mL/hr
  • 15 to 20 mL/hr (correct)
  • 20 to 25 mL/hr
  • 5 to 10 mL/hr

What happens when there is an elevation in the volume of one compartment in the cranial cavity?

  • The volume of the other compartments remains the same
  • The intracranial pressure decreases
  • The volume of the other compartments increases
  • The volume of one or more of the other compartments can be reduced (correct)

What is the composition of the cranial cavity?

<p>Brain tissue, CSF, and blood vessels (B)</p> Signup and view all the answers

What is the consequence of an increase in one component of the cranial cavity?

<p>An equal and opposite decrease in one or both of the remaining components (A)</p> Signup and view all the answers

What is the purpose of the Monro-Kellie doctrine?

<p>To explain the relationship between the components of the cranial cavity and the intracranial pressure (C)</p> Signup and view all the answers

Cerebral venous thrombosis occurs more frequently in which gender?

<p>Women (D)</p> Signup and view all the answers

Which of the following symptoms is NOT associated with cerebral venous thrombosis?

<p>Fever (C)</p> Signup and view all the answers

What is the importance of an elevated D-dimer level in diagnosing cerebral venous thrombosis?

<p>It supports the diagnosis of cerebral venous thrombosis (D)</p> Signup and view all the answers

What imaging modality is used to demonstrate hyperdensities along the left tentorium and involving the left sigmoid sinus?

<p>Computed Tomogram (CT) without intravenous contrast (C)</p> Signup and view all the answers

In which age group should cerebral venous thrombosis be considered in patients with acute, subacute, or chronic headache with unusual features?

<p>Patients 50 years of age (C)</p> Signup and view all the answers

What is a characteristic of cerebral venous thrombosis on imaging?

<p>Hyperdensities along the left tentorium (A)</p> Signup and view all the answers

What happens when tissue demand exceeds autoregulation or CBF declines for pathologic reasons?

<p>The arteriovenous oxygen difference extraction increases (B)</p> Signup and view all the answers

What is the formula for calculating cerebral perfusion pressure?

<p>CPP = MAP - ICP (B)</p> Signup and view all the answers

What percentage of trauma deaths are caused by head injury?

<p>50% (B)</p> Signup and view all the answers

What is the primary cause of primary injury in traumatic brain injury?

<p>External physical forces applied to the head (D)</p> Signup and view all the answers

What is the estimated number of head injury cases every year?

<p>500,000 to 1 million (B)</p> Signup and view all the answers

What is the percentage of head injuries classified as moderate to severe?

<p>20% (D)</p> Signup and view all the answers

What happens to CSF production when there is an increase in intracranial backpressure?

<p>It remains unaffected (C)</p> Signup and view all the answers

What is the normal range of CBF in mL/100 g of brain tissue per minute?

<p>30 to 100 (A)</p> Signup and view all the answers

What determines the blood flow to a particular area of the brain?

<p>Metabolic demand from neuronal activity (B)</p> Signup and view all the answers

What is the effect of an elevated or decreased arterial PCO2 on the autoregulation curve?

<p>It shifts the curve as indicated (C)</p> Signup and view all the answers

What happens to the autoregulation curve in the setting of traumatic brain injury?

<p>It becomes more pronounced (D)</p> Signup and view all the answers

What is the purpose of autoregulation in the brain vasculature?

<p>To match blood flow to tissue metabolic demand (A)</p> Signup and view all the answers

What is the goal of treatment in traumatic brain injury?

<p>To maintain CPP at or above 70 mmHg (D)</p> Signup and view all the answers

What is the predictor of poor outcome in traumatic brain injury?

<p>SBP &lt; 90 mmHg or a PaO2 &lt; 60 mmHg (B)</p> Signup and view all the answers

What is the treatment approach for epidural and subdural hematomas?

<p>Craniotomy centered on the clot (B)</p> Signup and view all the answers

What is the estimated annual incidence of cerebral venous thrombosis in the general population?

<p>3 to 4 cases per million (D)</p> Signup and view all the answers

In pregnant women, what is the incidence of cerebral venous thrombosis?

<p>12 cases per 100 000 deliveries (C)</p> Signup and view all the answers

What is the volume of clot or contusion that is considered operable?

<p>30 mL (A)</p> Signup and view all the answers

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