Neuroscience Quiz: Brain Structures and Functions
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Questions and Answers

Which artery primarily supplies blood to the internal capsule and most of the lateral hemispheres of the brain?

  • Anterior cerebral artery (ACA)
  • Middle cerebral artery (MCA) (correct)
  • Posterior cerebral artery (PCA)
  • Basilar artery
  • A patient exhibits impaired motor control, difficulty with planning, and notable changes in personality. Which lobe of the brain is MOST likely affected?

  • Temporal lobe
  • Occipital lobe
  • Parietal lobe
  • Frontal lobe (correct)
  • Which of the following structures separates the precentral and postcentral gyrus?

  • Sylvian fissure
  • Parieto-occipital sulcus
  • Central sulcus (correct)
  • Deep longitudinal fissure
  • What critical function is primarily associated with the brainstem, and loss of function may result in death?

    <p>Vital functions such as cardiovascular activity and respiration (C)</p> Signup and view all the answers

    If a patient experiences sensory loss due to an injury of the cerebellum, which side of the body will the loss occur?

    <p>Ipsilateral (B)</p> Signup and view all the answers

    Which of the following symptoms is NOT associated with Horner’s syndrome?

    <p>Vasoconstriction of skin to face (C)</p> Signup and view all the answers

    What is a common early indicator of autism spectrum disorders in infants?

    <p>Poor eye contact (C)</p> Signup and view all the answers

    What biological factor is significantly increased in the cerebrospinal fluid (CSF) of individuals with fibromyalgia?

    <p>Substance P (B)</p> Signup and view all the answers

    Which of the following correctly describes a key feature of Complex Regional Pain Syndrome (CRPS)?

    <p>Pain is out of proportion to the original injury (D)</p> Signup and view all the answers

    Which type of nerve fiber has the slowest conduction velocity?

    <p>C fibers (B)</p> Signup and view all the answers

    In a three-order neuron pathway, which of the following describes the location of the second-order neuron's cell body?

    <p>Dorsal horn, ipsilateral side (D)</p> Signup and view all the answers

    Which of the following is NOT sensory information carried by the spinothalamic tract?

    <p>Proprioception (A)</p> Signup and view all the answers

    What is the primary function of dendrites in a neuron?

    <p>Detecting stimuli (D)</p> Signup and view all the answers

    What is the role of radial glia during cell migration in brain development?

    <p>Guiding migrating cells to their permanent location (C)</p> Signup and view all the answers

    During which stage of development does gastrulation occur?

    <p>Embryonic stage (C)</p> Signup and view all the answers

    Which structure does NOT arise from the mesoderm?

    <p>Stomach (D)</p> Signup and view all the answers

    What is the neural crest responsible for forming?

    <p>Nerves of the PNS (C)</p> Signup and view all the answers

    Which primary brain vesicle gives rise to the cerebellum and pons?

    <p>Rhombencephalon (D)</p> Signup and view all the answers

    What event marks the beginning of the fetal stage of development?

    <p>The 8th week of gestation (C)</p> Signup and view all the answers

    What is the process by which a cell takes on the specific characteristics of a neuron termed?

    <p>Differentiation (D)</p> Signup and view all the answers

    During neural development, when does myelination of axons begin?

    <p>The fourth month of gestation (C)</p> Signup and view all the answers

    Which of the following is a result of the failure of the anterior neural tube to close?

    <p>Anencephaly (B)</p> Signup and view all the answers

    In spina bifida cystica, what is the difference between a meningocele and a myelomeningocele?

    <p>Meningocele involves herniation of the meninges only, while myelomeningocele involves herniation of both the meninges and spinal cord. (B)</p> Signup and view all the answers

    Which of the following best describes the role of neuroglia?

    <p>To provide support and metabolic support to neurons. (C)</p> Signup and view all the answers

    What is the primary function of the axon hillock?

    <p>Generating action potentials. (D)</p> Signup and view all the answers

    What is the most severely affected sensation in demyelination?

    <p>Vibratory sense (B)</p> Signup and view all the answers

    A nerve root lesion affects sensation in what pattern?

    <p>Dermatomal pattern (A)</p> Signup and view all the answers

    What type of lesion results in contralateral pain and temperature loss below its level?

    <p>Hemi-section lesion (D)</p> Signup and view all the answers

    What is the primary function of an MRI?

    <p>Shows soft tissue structures (C)</p> Signup and view all the answers

    Which sensory receptor responds to changes in temperature?

    <p>Thermoreceptors (C)</p> Signup and view all the answers

    Which of the following accurately describes the role of the spinothalamic tract?

    <p>Processes temperature and nociception (B)</p> Signup and view all the answers

    In a complete transection of the spinal cord, what sensation will be lost below the level of the lesion?

    <p>All sensations (B)</p> Signup and view all the answers

    Which imaging technique is primarily used to assess blood flow and metabolic functions in the brain?

    <p>PET scan (C)</p> Signup and view all the answers

    What type of sensory receptor is primarily adapted for detecting rapid changes in stimuli?

    <p>Phasic receptors (C)</p> Signup and view all the answers

    What kind of sensory loss is expected in an anterior cord lesion?

    <p>Loss of pain and crude touch (C)</p> Signup and view all the answers

    Which of the following correctly describes the function of DTI in brain imaging?

    <p>Measures water diffusion in axons (B)</p> Signup and view all the answers

    What is the role of the dorsal column in sensory information processing?

    <p>Carries discriminative touch and proprioceptive information (A)</p> Signup and view all the answers

    Where does the spinal cord end in humans?

    <p>At the conus medullaris (A)</p> Signup and view all the answers

    What characterizes the first-order neuron in the DCML pathway?

    <p>Receives sensory input from the dorsal column and ascends contralaterally (A)</p> Signup and view all the answers

    What is the primary difference between recovery and compensation in the context of neural plasticity?

    <p>Recovery restores function in damaged neural systems, while compensation uses unaffected systems. (C)</p> Signup and view all the answers

    Which principle does NOT enhance experience-dependent neuroplasticity?

    <p>Passive observation (C)</p> Signup and view all the answers

    What is a crucial critical period for visual development?

    <p>Between ages 3 to puberty (C)</p> Signup and view all the answers

    What neurotransmitter is primarily used by the parasympathetic nervous system?

    <p>Acetylcholine (D)</p> Signup and view all the answers

    Which statement best describes the function of the sympathetic nervous system?

    <p>It prepares the body for stressful situations. (B)</p> Signup and view all the answers

    What role do endorphins play in relation to pain?

    <p>They inhibit pain perception. (D)</p> Signup and view all the answers

    What typically causes referred pain?

    <p>Converging nociceptive fibers in the spinal cord. (D)</p> Signup and view all the answers

    What is NOT a characteristic of the autonomic nervous system?

    <p>It directly controls skeletal muscle movements. (C)</p> Signup and view all the answers

    What is an effect of high-intensity treadmill training in neuroplasticity?

    <p>It necessitates thousands of repetitions for motor recovery. (B)</p> Signup and view all the answers

    What distinguishes experience-expectant plasticity from experience-dependent plasticity?

    <p>Experience-expectant plasticity occurs during development, while experience-dependent continues throughout life. (A)</p> Signup and view all the answers

    Flashcards

    Central Nervous System (CNS)

    The CNS consists of the brain, spinal cord, and cranial nerves 1 & 2.

    Circle of Willis

    A network of arteries that supplies blood to the cerebral hemispheres of the brain.

    Frontal Lobe Functions

    Responsible for motor control, executive functioning, planning, and personality traits.

    Cerebellum Functions

    Involved in coordination, balance, and unconscious proprioception for motor control.

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    Action Potential

    The nerve impulse carried from one neuron to another via electrical signals.

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    Spina bifida prevention

    Spina bifida can be prevented with adequate folic acid levels in mothers.

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    Cerebral palsy

    A movement and postural disorder from permanent, nonprogressive brain damage.

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    Autism spectrum disorders

    A range of abnormal behaviors related to social skills and interactions.

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    Horner’s syndrome

    Affects sympathetic innervation leading to miosis, ptosis, and anhidrosis.

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    Fibromyalgia

    Characterized by muscle tenderness, stiffness, and biologically amplified pain signals.

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    Three-order neuron pathway

    Neurons involved in relaying sensory information to the brain, divided into three orders.

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    First order neuron

    The neuron that transmits sensory information from the periphery to the spinal cord's dorsal horn.

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    Second order neuron

    The neuron that crosses the midline from the spinal cord to the thalamus, conveying sensory information further up.

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    Third order neuron

    The neuron that transmits sensory information from the thalamus to the parietal lobe of the brain.

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    Spinothalamic tract

    Pathway that carries nociception, temperature, and crude touch information to the brain.

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    Neuron

    A nerve cell that receives and transmits signals, controlling body functions.

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    Axon

    The conducting portion of a neuron that transmits electrical impulses away from the cell body.

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    Dendrites

    Branch-like structures of a neuron that receive incoming signals from other neurons.

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    Soma (Cell Body)

    The central part of a neuron containing the nucleus and cytoplasm.

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    Neuroglia

    Supporting cells in the nervous system that protect neurons and provide metabolic support.

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    Myotome

    Embryonic structure that develops into muscle tissue.

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    Dermatome

    Embryonic structure that develops into the dermis of the skin.

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    Neurulation

    The process of forming the neural tube during embryonic development.

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    Spina Bifida

    A condition resulting from improper closure of the neural tube in the lower spine.

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    Anencephaly

    Failure of the anterior neural tube to close, resulting in incomplete brain formation.

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    Contralateral

    Refers to the opposite side of the body relative to a lesion.

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    Compression effects

    Can cause paresthesias and sensory losses like proprioception and light touch.

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    Demyelination

    Loss of myelin sheath affecting proprioception and vibratory sense.

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    Nerve root lesion

    Impaired sensation in a dermatomal pattern with motor loss in a myotomal pattern.

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    Complete transection

    All sensation lost 1-2 levels below the level of the lesion.

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    Brown-Sequard syndrome

    Hemi-section leads to contralateral pain/temperature loss and ipsilateral touch/proprioception loss.

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    Posterior column lesions

    Loss of conscious proprioception, vibration, and 2-point discrimination below the lesion.

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    Anterior cord lesion

    Loss of pain, temperature, and crude touch below the lesion level.

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    Lesion of thalamus

    Results in contralateral decrease or loss of sensation.

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    fMRI

    Measures changes in oxygen consumption to assess brain function.

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    Proprioceptors

    Sensors that provide internal sense of movement and joint position.

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    DCML pathway

    Transmits discriminative touch, proprioception, and vibration sensations.

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    EEG

    Records electrical impulses from the brain's cortex through scalp electrodes.

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    Sensory receptors types

    Includes exteroceptors, interoceptors, proprioceptors, responding to various stimuli.

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    Neural Plasticity

    The brain's ability to change its structure and function based on experience.

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    Recovery vs Compensation

    Recovery is restoration of function, while compensation involves unaffected systems taking over.

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    Experience-Expectant Plasticity

    Changes in the CNS organization that occur during development, driven by expected experiences.

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    Experience-Dependent Plasticity

    Changes in cellular structure based on unique experiences after injury.

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    Critical Period

    A sensitive time during which certain experiences shape neural wiring, like vision and language.

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    Sympathetic Nervous System (SNS)

    Part of the autonomic nervous system responsible for the 'fight or flight' response.

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    Parasympathetic Nervous System (PSNS)

    Part of the autonomic nervous system that conserves energy and promotes rest.

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    Nociceptors

    Sensors that detect harmful stimuli, signaling pain and injury.

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    Endorphins

    Natural pain suppressors released in response to stress or pain.

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    Study Notes

    Central Nervous System (CNS) Anatomy and Function

    • CNS comprises the brain, spinal cord, and cranial nerves 1 & 2. Major regions include the spinal cord, brainstem, cerebellum, and cerebrum.
    • Circle of Willis: A network of arteries supplying blood to the cerebral hemispheres.
      • Anterior Cerebral Artery (ACA): Branches supply the medial surface of frontal and parietal lobes.
      • Middle Cerebral Artery (MCA): Supplies internal capsule, globus pallidus, putamen, caudate, and most of the lateral hemispheres.
      • Posterior Cerebral Artery (PCA): Supplies midbrain, occipital lobe, and parts of medial and inferior temporal lobe.
    • Brain Lobes and Functions:
      • Frontal Lobe: Motor functions, executive functions, planning, and personality.
      • Parietal Lobe: Sensation processing.
      • Temporal Lobe: Language and hearing.
      • Occipital Lobe: Vision.
    • Brainstem Functions: Vital functions, cardiovascular activity, respiration, conveying information from cerebrum and spinal cord, cranial nerve nuclei, and consciousness.
    • Brain Structure and Sulci/Gyri:
      • Deep Longitudinal Fissure: Separates right and left hemispheres.
      • Central Sulcus: Separates precentral and postcentral gyri, both part of the frontal lobe.
      • Parieto-occipital Sulcus: Separates parietal and occipital lobes.
    • Communication Between Brain Areas: Presynaptic neuron transmits information to the postsynaptic neuron via action potentials (nerve impulses).
    • Cerebellum Function and Sensory Input:
      • Motor and nonmotor domains.
      • Comparator function (coordination, regulation, and modulation of motor behavior).
      • Sensory function: Unconscious proprioception, regulating balance and coordination of movement, quality control of movement.
      • Sensory loss with injury is ipsilateral for cerebellum.
      • Sensory losses include proprioception, light touch, fast nociception, heat, and slow nociception.
    • Demyelination: Affects proprioception and vibratory sense (most heavily myelinated).
    • Nerve Root Lesion: Impaired sensation in dermatomal pattern and loss of motor function in myotomal pattern.
    • Complete Transection: All sensation lost 1-2 levels below lesion level.
    • Hemi-section/Brown-Sequard Syndrome:
      • Pain and temperature interrupted below lesion contralaterally.
      • Pain and temperature interrupted at lesion ipsilaterally.
      • Discriminative touch and conscious proprioception lost below lesion ipsilaterally.
    • Posterior Column Lesions: Loss of conscious proprioception, vibration, and 2-point discrimination below lesion level.
    • Anterior Cord Lesion: Loss of pain, temperature, and crude touch below lesion level.
    • Brainstem Lesions: Contralateral or ipsilateral signs, depending on lesion location.
    • Thalamus Lesion: Contralateral decrease or loss of sensation.
    • Somatosensory Cortex: Contralateral impairments; discriminative sensations include stereognosis, conscious proprioception, 2-point discrimination, localization of touch, and fast nociception.
    • Spinal Cord Anatomy: Extends from foramen magnum to L1 vertebra (ends at conus medullaris). Blood supply via 3 spinal arteries: 1 anterior (⅔), 2 posterior (⅓). Dorsal (sensory) and ventral (motor) roots join to form nerve roots.
    • Imaging Techniques:
      • PET: Shows metabolic functions, blood flow (radioactive material).
      • CT: Detailed images of bones/fractures (X-rays).
      • MRI: Shows soft tissue detail (magnetic field).
      • MRA: Visualizes blood vessels in detail (contrast medium).
      • BOLD MRI: Detects areas of oxygen consumption; assesses brain function.
      • DTI: Detailed white matter tract imaging; detects ischemic stroke (water diffusion).
      • EEG: Records electrical impulses from brain cortex; detects seizures.

    Sensory Receptors and Functions

    • Exteroreceptors: Respond to external environment.
    • Interoreceptors: Respond to internal environment.
    • Proprioceptors: Internal sense of movement; joint position sense.
    • Tonic Receptors: Slowly adapting receptors.
    • Phasic Receptors: Fast adapting receptors.
    • Mechanoreceptors: Respond to mechanical deformation.
    • Thermoreceptors: Respond to temperature gradients across the skin.
    • Nociceptors: Respond to tissue-damaging stimuli.
    • Chemoreceptors: Respond to chemical constituents.

    Dorsal Column-Medial Lemniscus (DCML) Pathway

    • Discriminative tactile sensation, kinesthesia/proprioception and stereognosis.
    • Heavily myelinated.
    • Three-neuron pathway:
      • First order: Enters dorsal column, ascends ipsilaterally to medulla; cell body in DRG.
      • Second order: Crosses, travels to contralateral dorsal column nuclei, ascends to thalamus; cell body in medulla.
      • Third order: Thalamus to parietal lobe; cell body in thalamus.
    • Carries discriminative touch, conscious proprioception, and vibration.

    Spinothalamic Tract

    • Part of the anterolateral system; for nociception, temperature, and crude touch.
    • Lightly myelinated.
    • Three-neuron pathway:
      • First order: Enters spinal cord, synapses in dorsal horn; cell body in DRG.
      • Second order: Crosses midline, ascends in anterolateral white matter to thalamus; cell body in dorsal horn.
      • Third order: Thalamus to parietal lobe; cell body in thalamus.
    • Carries nociception (fast), temperature, and crude touch.

    Nerve Structure and Function

    • Neurons: Nerve cells; receive and transmit signals; responsible for control, integration, and responses of body functions.
    • Parts: Axon (conducting), dendrites (receptive), soma (cell body).
    • Neuroglia: Supporting cells; protect and supply metabolic support to neurons.
    • Information Transmission: Axons (nerve fibers) forming bundles (tracts/pathways).

    Nerve Damage

    • Description of damage effects not provided.

    CNS Development

    • Zygote: Fertilized egg; divides into cells.
    • Morula: Collection of blastomeres (cells).
    • Blastocyst: Spheres of cells; outer layer becomes placenta, inner layer embryo.
    • Embryo: Until 8 weeks; Fetus: After 8 weeks.
    • Gastrulation: Single-layered blastula reorganized into trilaminar gastrula (ectoderm, mesoderm, endoderm).
    • Neurulation: Formation of neural tube (3rd week gestation).
    • Neural Plate: Thickening of ectoderm.
    • Neural Tube: Forms CNS.
    • Neurocele: Forms ventricles and spinal cord.
    • Neural Crest: Forms PNS.
    • Somite Development: Develop from mesoderm (day 20-30).
    • Myotome: Embryonic part of somite that becomes muscle.
    • Dermatome: Embryonic part of somite that becomes dermis.
    • Brain Formation (primary vesicles): 4 weeks.
      • Prosencephalon (forebrain), Mesencephalon (midbrain), Rhombencephalon (hindbrain).
    • Brain Formation (secondary vesicles): 5 weeks.
      • Telencephalon → cerebral hemispheres (lateral ventricles)
      • Diencephalon → thalamus, hypothalamus, optic vesicles
      • Mesencephalon → midbrain
      • Rhombencephalon → cerebellum, pons, medulla
    • Fetal Stage (8 weeks-birth): More nervous system development, myelination begins.
    • Cellular Development: Proliferation, migration, differentiation (growth cones, synaptogenesis).
    • Myelination: Begins 4th month, most sheaths complete by 3 years.
    • Clinical Conditions: Descriptions and causes of anencephaly, spina bifida, cerebral palsy, autism spectrum disorders, Horner's syndrome, fibromyalgia, complex regional pain syndrome, listed.

    Neurotransmitters

    • General descriptions of neurotransmitters (e.g., acetylcholine, norepinephrine, dopamine, GABA).

    Neurological Plasticity

    • Neural plasticity: Ability of NS to change functions, chemical profiles, or structure.
      • Recovery vs. compensation.
    • Experience-expectant plasticity: Changes during development.
    • Experience-dependent plasticity: Cellular structure changes.
    • Critical periods: Specific times for development.
    • Treatments: Examples of treatment approaches.

    Autonomic Nervous System (ANS)

    • SNS: Increase energy utilization; fight-or-flight (stress, exercise).
      • Efferent pathway, innervates adrenal medulla, vasculature, etc.
      • Paravertebral ganglia, short preganglionic, long postganglionic fibers; uses ACh (pre) & EPI/NE/ACh (post).
    • PSNS: Most active at rest; energy conservation, increases digestion, promotes relaxation.
      • Efferent pathway, PS fibers innervate pupil, salivary glands, etc.
      • Long preganglionic, short postganglionic fibers, ganglia near/in organ.
      • Uses ACh for both pre and post.
    • SNS vs PSNS: Comparison table of functions.

    Pain

    • Nociceptors: Signal injury.
    • Referred pain: Perceived as coming from different origin due to shared secondary neuron in spinal cord; thalamus.
    • Spinothalamic tract mediates pain.
    • Antinociception: Suppression of pain.

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    Test your knowledge on key aspects of neuroscience including understanding brain structures, their functions, and related neurological conditions. This quiz covers essential topics such as blood supply to the brain, brain damage effects, and syndromes associated with nerve conditions.

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