Neuroscience Quiz: Brain Functions and Mechanisms
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Questions and Answers

Which type of brain matter is primarily responsible for the brain's computation?

  • Myelin
  • White matter
  • Grey matter (correct)
  • Axons

What is the primary cause of the white color of white matter in the brain?

  • Presence of neurotransmitters
  • The density of neurons
  • Myelination of axons (correct)
  • High glucose levels

Which biological factor is critical for both short-term and long-term impact on the nervous system?

  • Neurotransmitters
  • Dendrites
  • Oxygen (correct)
  • Synapses

What does the cortex of the brain mainly contribute to?

<p>Higher cognitive functions (C)</p> Signup and view all the answers

What concept explains that all brain areas can be functionally connected despite not being directly linked?

<p>Functional connectivity (B)</p> Signup and view all the answers

What triggers the release of neurotransmitters into the synaptic cleft?

<p>Action potential (C)</p> Signup and view all the answers

How do receptors affect the receiving neuron?

<p>By changing the ion charge inside (A)</p> Signup and view all the answers

What is the primary function of selective serotonin reuptake inhibitors (SSRIs)?

<p>Prevent the reuptake of serotonin (C)</p> Signup and view all the answers

What mechanism represents the action of drugs that mimic neurotransmitters?

<p>Agonism (A)</p> Signup and view all the answers

What happens to free neurotransmitters in the synapse after their function is complete?

<p>They are reabsorbed or broken down (A)</p> Signup and view all the answers

What is synaptic plasticity primarily concerned with?

<p>Changes in the strength of connections between synapses (B)</p> Signup and view all the answers

Which process specifically involves the formation and elimination of synapses?

<p>Synaptogenesis and synaptic pruning (C)</p> Signup and view all the answers

What primary function does the somatic nervous system serve?

<p>Transmitting information from the senses to muscles (B)</p> Signup and view all the answers

What is the effect of drugs that act directly on ion channels?

<p>Modify ion flow into neurons (B)</p> Signup and view all the answers

What is functional reorganization in the context of neuroplasticity?

<p>The redistribution of brain functions to different areas (B)</p> Signup and view all the answers

Which type of neuron is specialized for receiving signals from other neurons?

<p>Dendrite (A)</p> Signup and view all the answers

Which of the following describes a characteristic of neurotransmitter receptors?

<p>They can only be activated by specific neurotransmitters (A)</p> Signup and view all the answers

What does neurogenesis refer to?

<p>The creation of new neurons (A)</p> Signup and view all the answers

What is a potential consequence of dysfunction in proteins within the nervous system?

<p>Altered neuronal function (B)</p> Signup and view all the answers

What defines the resting membrane potential of a neuron?

<p>A voltage of approximately -70mV (A)</p> Signup and view all the answers

Which method allows for direct examination of brain tissue?

<p>Post-mortem measures (C)</p> Signup and view all the answers

What occurs during depolarization of a neuronal membrane?

<p>Positive ions flow into the cell (D)</p> Signup and view all the answers

What might cause neural cell death in the brain?

<p>Over-excitation or disease (D)</p> Signup and view all the answers

What is the role of the autonomic nervous system?

<p>Monitoring and controlling bodily functions without conscious thought (A)</p> Signup and view all the answers

What is a common result of practice in relation to brain activity?

<p>Reduction in brain activity and distribution of activity (C)</p> Signup and view all the answers

What initiates an action potential in a neuron?

<p>Depolarization caused by positive ions entering the cell (B)</p> Signup and view all the answers

Which method alters brain function to study its effects?

<p>Lesions and genetic changes (D)</p> Signup and view all the answers

How is the signal passed from one neuron to another when an action potential reaches the axon terminal?

<p>By releasing neurotransmitters into the synaptic cleft (B)</p> Signup and view all the answers

Which component of a neuron is responsible for conducting electrical impulses away from the cell body?

<p>Axon (B)</p> Signup and view all the answers

What is misleading about the idea of specific brain areas being dedicated to certain functions?

<p>Certain brain areas are exclusive to specific functions. (A), Functions are solely determined by the social context. (D)</p> Signup and view all the answers

What is highlighted as a more helpful way to understand psychological disorders?

<p>Using different levels of explanation. (B)</p> Signup and view all the answers

What does neurobiology primarily study?

<p>The molecular and cellular aspects of the nervous system. (C)</p> Signup and view all the answers

Which of the following descriptions best defines systems neuroscience?

<p>The study of neural networks and brain circuits. (B)</p> Signup and view all the answers

What role does psychopharmacology play in neuroscience?

<p>It studies the neurobiology of substances that alter mental states. (C)</p> Signup and view all the answers

Which statement reflects the relationship between neuro disciplines?

<p>They have significant overlap and similar naming conventions. (A)</p> Signup and view all the answers

What is studied in computational neuroscience?

<p>The computational modeling of neural networks. (C)</p> Signup and view all the answers

What common feature do antipsychotics and street drugs share in psychopharmacology?

<p>Both can alter mental states. (B)</p> Signup and view all the answers

What is the primary composition of grey matter in the brain?

<p>Neuronal cell bodies (A)</p> Signup and view all the answers

Which factor is known to impact the nervous system in the long-term?

<p>Oxygen levels (D)</p> Signup and view all the answers

What is a key characteristic of white matter in the brain?

<p>Includes myelinated axons (C)</p> Signup and view all the answers

Which structure of the brain is primarily responsible for folding to increase surface area?

<p>Cortex (A)</p> Signup and view all the answers

How does the concept of a 'network of networks' relate to brain function?

<p>Brain areas can communicate through indirect signaling pathways (A)</p> Signup and view all the answers

What are the two main divisions of the nervous system?

<p>Central nervous system and peripheral nervous system (D)</p> Signup and view all the answers

Which part of the peripheral nervous system is responsible for voluntary movements?

<p>Somatic nervous system (B)</p> Signup and view all the answers

What occurs when an action potential propagates down an axon?

<p>A temporary shift from negative to positive membrane potential (D)</p> Signup and view all the answers

What is the primary function of the autonomic nervous system?

<p>To maintain essential bodily functions without conscious control (D)</p> Signup and view all the answers

Which part of a neuron is primarily responsible for receiving neurotransmitters?

<p>Dendrite (B)</p> Signup and view all the answers

What is synaptogenesis?

<p>The creation and removal of synapses. (B)</p> Signup and view all the answers

What maintains the resting membrane potential in a neuron?

<p>The balance of positive and negative ions across the membrane (D)</p> Signup and view all the answers

Which process is described as a limited ability in the human brain?

<p>Neurogenesis (B)</p> Signup and view all the answers

Which of the following best describes the action potential's initiation?

<p>It is initiated by the flow of sodium ions into the cell (B)</p> Signup and view all the answers

What characterizes the sympathetic nervous system?

<p>It is responsible for fight or flight responses (D)</p> Signup and view all the answers

What does functional reorganization in the brain involve?

<p>Redistributing functions to different brain regions. (C)</p> Signup and view all the answers

What type of study would involve altering brain function to examine the outcome?

<p>Interventional studies (A)</p> Signup and view all the answers

Which of the following outcomes is a consequence of practice based on neuroplasticity?

<p>Reduced brain activity with enhanced efficiency. (A)</p> Signup and view all the answers

What does neuroplasticity encompass?

<p>All changes related to learning and adaptation in the brain. (D)</p> Signup and view all the answers

Which term describes the process of neurons dying as a natural mechanism?

<p>Apoptosis (B)</p> Signup and view all the answers

What does synaptic plasticity specifically refer to?

<p>Changes in the strength of connections between synapses. (C)</p> Signup and view all the answers

Why is the notion that certain brain areas are dedicated to specific functions considered misleading?

<p>Different brain areas can perform multiple functions. (C)</p> Signup and view all the answers

What is the main focus of systems neuroscience?

<p>Neural networks and their functioning. (B)</p> Signup and view all the answers

Which of the following includes substances that alter mental states?

<p>Psychopharmacology. (A)</p> Signup and view all the answers

How should psychological disorders be categorized according to the content?

<p>Using multiple, overlapping approaches. (D)</p> Signup and view all the answers

What area of study focuses on the nervous system at a molecular and cellular level?

<p>Neurobiology. (A)</p> Signup and view all the answers

What can lead to confusion among different 'neuro' disciplines?

<p>Their names are often similar but meanings differ. (A)</p> Signup and view all the answers

Which statement best describes an approach to understanding cognitive functions?

<p>Cognition should be understood through various overlapping disciplines. (D)</p> Signup and view all the answers

Which type of neuroscience specifically studies the interactions of medications and drugs with the nervous system?

<p>Neuropsychopharmacology. (B)</p> Signup and view all the answers

What role do receptors play in neuronal communication?

<p>They activate ion channels allowing ions to enter the neuron. (D)</p> Signup and view all the answers

What happens to neurotransmitters after they have performed their function?

<p>They are reabsorbed by the axon terminal or broken down by enzymes. (D)</p> Signup and view all the answers

What does the action of SSRIs primarily achieve in the synaptic cleft?

<p>Prevents reuptake of serotonin, increasing its availability. (D)</p> Signup and view all the answers

What is the term for drugs that mimic neurotransmitters and activate specific receptors?

<p>Agonists. (D)</p> Signup and view all the answers

How do drugs that act on ion channels influence neuronal activity?

<p>They allow or block the flow of ions in and out of the neuron. (A)</p> Signup and view all the answers

What is one way that drugs can selectively affect certain brain circuits or systems?

<p>They target specific neurotransmitters and receptors that are unique to those circuits. (B)</p> Signup and view all the answers

What impact can dysfunction in proteins have on the nervous system?

<p>It can disrupt various biological processes critical for neural function. (C)</p> Signup and view all the answers

Which of the following is NOT a way that drugs can modify neurotransmitter activity?

<p>They can change the color of neurotransmitters. (A)</p> Signup and view all the answers

Flashcards

What is Neuroscience?

The study of the nervous system, encompassing both the brain and other related structures.

Central Nervous System

Comprises the brain and spinal cord, acting as the central processing unit for the nervous system.

Peripheral Nervous System

Handles communication between the central nervous system and the body's external environment. It transmits sensory information and controls muscle movement.

Somatic Nervous System

A part of the peripheral nervous system responsible for voluntary actions, including sensations and muscle movements.

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Autonomic Nervous System

A specialized part of the peripheral nervous system that regulates automatic bodily functions without conscious control.

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Sympathetic Nervous System

The branch of the autonomic nervous system that triggers the 'fight-or-flight' response. It prepares the body for stressful situations.

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Parasympathetic Nervous System

The branch of the autonomic nervous system responsible for 'rest-and-digest' functions. It promotes relaxation and energy conservation.

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What is a Neuron?

The basic building block of the nervous system, responsible for transmitting information throughout the body.

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Brain as a Network

The brain is a network of interconnected regions, even if not directly connected by white matter tracts, information can be transferred indirectly, allowing for functional communication between all areas.

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Cortex

The outer layers of the brain, responsible for higher cognitive processes, including conscious actions and deliberate thinking.

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Grey Matter

The brain's 'computation center', containing the cell bodies of neurons, responsible for processing information.

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White Matter

The brain's 'cabling', composed of axons that transmit information between neurons, facilitating communication across the brain.

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Myelination

The fatty tissue that surrounds axons, speeding up signal transmission. Damage to myelin can lead to disorders like multiple sclerosis.

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Synapse

The point where two neurons meet, enabling communication through the release and reception of neurotransmitters.

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Neurotransmitters

Chemical messengers that transmit signals between neurons across the synaptic cleft.

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Receptors

Specialized proteins on the receiving neuron that bind to specific neurotransmitters, triggering the neuron's response.

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Neurotransmitter reuptake

The process of removing neurotransmitters from the synaptic cleft, either by breaking them down with enzymes or reabsorbing them back into the sending neuron.

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Selective serotonin reuptake inhibitors (SSRIs)

Drugs that block the reuptake of neurotransmitters, increasing their concentration in the synapse and enhancing their effects.

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Agonists

Drugs that mimic the action of neurotransmitters, binding to their specific receptors and triggering the same effects.

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Antagonists

Drugs that block the action of neurotransmitters, preventing them from binding to their receptors and initiating a response.

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Selective drug action

The ability of drugs to selectively target specific brain circuits, behaviors, and perceptual systems due to the diverse roles of different neurotransmitters and receptors.

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Neuroplasticity

The ability of the brain to change and adapt in response to experiences or stimuli.

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Synaptic plasticity

Changes in the strength of connections between synapses, affecting how neurons communicate with each other.

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Synaptogenesis

The formation of new synapses, allowing for new connections and learning.

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Synaptic pruning

The elimination of unused synapses, streamlining brain networks and promoting efficiency.

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Neurogenesis

The creation of new neurons, a limited process in the human brain.

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Neuronal migration

The movement of neurons from their birthplace to their final destination in the brain.

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Functional reorganisation

When brain functions, like vision, are taken over by other brain areas due to damage or adaptation.

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Direct interventional studies

A research method that involves directly altering brain function, like using drugs or creating lesions, to observe the effects.

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Levels of Explanation

Different approaches to understanding the brain, from the social to the biological, offer various levels of explanation. This helps avoid classifying disorders as solely 'social' or 'biological', recognizing that they can involve multiple levels.

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Neurobiology

The nervous system and its functions at the molecular and cellular level, exploring aspects like neuronal signaling, cell physiology, genetics, and interventions.

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Systems Neuroscience

The study of groups of interconnected neurons, examining how they work together to form circuits in the brain.

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Psychopharmacology

The study of how substances affect mental states, including medications, common drugs, street drugs, and industrial chemicals.

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Brain Area Specialization

Areas of the brain are involved in various functions, but none are dedicated exclusively to a single function.

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Cortical Column

A group of interconnected neurons forming a functional unit within the cortex.

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What is Neural Plasticity?

Changes in brain structure and function that help us learn and adapt.

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What is Synaptic Plasticity?

The process of strengthening or weakening connections between neurons.

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What is Synaptogenesis?

The creation of new connections between neurons.

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What is Synaptic Pruning?

The removal of unused connections between neurons.

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What is Neurogenesis?

The process of generating new neurons.

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What is Neuronal Migration?

The movement of neurons from their birthplace to their final location.

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What is Functional Reorganization?

The relocation of brain functions to different brain areas.

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What are Direct Interventional Studies?

Studies that directly change brain function to observe the effects.

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What is the Cortex?

The outermost layer of the brain, responsible for complex cognitive functions like planning, decision-making, and conscious actions. It's made up of grey matter and is folded to increase surface area.

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What is White Matter?

The brain's 'wiring', formed by long, thin fibers called axons. It transmits electrical signals between neurons, allowing for communication across the brain.

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What is Grey Matter?

The brain's 'computing' center, composed of neuron cell bodies that process information. It's called 'grey' due to its darker appearance.

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What is Neuroplasticity?

The brain's ability to change and adapt in response to experiences or stimuli. This includes strengthening existing connections, forming new ones, and even creating new neurons in some cases.

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What is Transcranial Magnetic Stimulation (TMS)?

A technique that uses magnetic fields to manipulate brain activity, allowing researchers to study specific brain regions and their functions. It's a non-invasive method.

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Neuron

The fundamental unit of the nervous system responsible for transmitting information.

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Action Potential

The electrical signal that travels down the axon of a neuron, triggered by the flow of ions through ion channels.

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What is a Synapse?

The space between two neurons where communication occurs.

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What are Neurotransmitters?

Chemical messengers released by neurons to transmit signals across the synapse.

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What are Receptors?

Specialized proteins on the receiving neuron that bind to specific neurotransmitters, triggering a response.

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What is Neurotransmitter Reuptake?

The process of removing neurotransmitters from the synaptic cleft.

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What are SSRIs?

Drugs that block the reuptake of neurotransmitters, increasing their concentration in the synapse.

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What are Agonists?

Drugs that mimic the action of neurotransmitters, binding to their specific receptors and triggering the same effects.

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What are Antagonists?

Drugs that block the action of neurotransmitters, preventing them from binding to their receptors.

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What is Selective Drug Action?

The ability of drugs to selectively target specific brain circuits, behaviors, and perceptual systems due to the diverse roles of different neurotransmitters and receptors.

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Synaptic Transmission

The study of how neurons transmit information across the synapse using chemical messengers called neurotransmitters.

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Study Notes

Introduction to Neuroscience

  • Neuroscience is the study of the nervous system, encompassing more than just the brain.
  • The nervous system is fundamentally divided into the central nervous system (CNS) and the peripheral nervous system (PNS).
  • The nervous system's functions are greatly affected by various factors including proteins, cellular metabolic processes, large-scale bodily processes like oxygen and nutrient availability, and hormonal influences.
  • The generation and regeneration of cells is also important, as seen in neurodevelopment and stem cell therapy, as well as disease processes such as Alzheimer's Disease.

Central Nervous System (CNS)

  • The CNS consists of the brain and spinal cord.
  • The brain is responsible for complex functions like thought, memory, and action.
  • The spinal cord's function is primarily to transmit information between the brain and the rest of the body.

Peripheral Nervous System (PNS)

  • The PNS comprises the nerves extending beyond the CNS.
  • It is divided into two main branches: the somatic nervous system and the autonomic nervous system.

Somatic Nervous System

  • The somatic nervous system deals with voluntary actions.
  • It transmits information between the sensory organs and the muscles.
  • This system has two types of nerves : sensory nerves (sensation) and motor nerves (muscle contraction).
  • Spinal nerves transmit information via the spine
  • Cranial nerves transmit information via the brainstem

Autonomic Nervous System

  • The autonomic nervous system regulates involuntary functions.
  • It maintains essential bodily functions like breathing, digestion, and heart rate.
  • This system comprises two branches: the sympathetic nervous system (fight or flight) and the parasympathetic nervous system (rest and digest).

Neuron

  • The basic unit of the nervous system is the neuron.

  • Neurons consist of cell bodies, axons, dendrites.

  • The cell body houses the nucleus and other organelles, responsible for the cell's metabolism.

  • The axon transmits electrical impulses, typically in a myelin-sheathed fibre.

  • Myelin sheaths speed up transmission

  • Dendrites receive signals from other neurons.

  • Signal transmission progresses from dendrites to cell body to axon.

  • Although all neurons have similar basic components, many diverse types exist, each specialized for specific functions.

Communication (action potential)

  • An electrical signal, the action potential, travels down the axon.
  • Action potential results from the movement of charged particles (ions) across the axon membrane through channels.
  • An unequal distribution of ions creates a resting membrane potential (-70mV).
  • Positive ions flow into the axon, causing depolarization (change in membrane potential), triggering further channels to open—propagating the signal.

Communication between neurons

  • Communication occurs at synapses.
  • Neurotransmitters are released from the presynaptic neuron into the synaptic cleft.
  • Receptors on the postsynaptic neuron receive the neurotransmitters.
  • These events result in a change in the postsynaptic neuron's membrane potential.
  • Neurotransmitters can be broken down by enzymes or reabsorbed by the presynaptic terminal.

Drug Action

  • Drugs can modify neuron function at various levels.
  • Some drugs inhibit the reuptake of neurotransmitters, leading to increased neurotransmitter availability.
  • Other drug types mimic or block neurotransmitters to affect their receptors.
  • Drugs can modify the function of ion channels in the membrane, changing the strength of the action potential.

Many Biological Factors

  • Any factor that affects the nervous system can influence human function.
  • Proteins, cell processes (e.g., neurodevelopment), and large-scale body factors (e.g., oxygen, glucose, hormones, and nutrients) all play crucial roles.
  • The generation and regeneration of cells is important (e.g., Alzheimer's and stem cell therapy).

Brain Lobes

  • The brain is divided into lobes: frontal, parietal, temporal, and occipital. Each lobe plays a role in specific cognitive functions.

Neuroanatomy

  • Gray matter is composed of cell bodies and involved in computation, processing information.
  • White matter is comprised of myelinated axons, which transmit signals across different brain regions and resemble "wiring" of the brain.
  • The cortex consists of folded layers of gray matter, a characteristic that increases the surface area for sophisticated neural processing.
  • Subcortical structures are deeper brain regions that serve specialized functions, for example the hippocampus and amygdala.

White Matter Tracts

  • White matter tracts are pathways that connect different areas of the brain.
  • Activity spread throughout the brain, even if connections are not directly shared by the regions.
  • A modular, interconnected network describes the brain.

Network Change/ Neuroplasticity

  • Neuroplasticity, the brain's potential to change in structure and function, underlies learning and adaptation.
  • Changes in the structures and functions of neural networks are key to learning new things and adapting behavior.

Types of Neuroplasticity

  • Synaptic plasticity: alterations in the strength of synaptic connections
  • Synaptogenesis and synaptic pruning: creating or eliminating synapses
  • Neurogenesis: generating new neurons
  • Neuronal migration: neurons traveling to different brain regions
  • Neural cell death (apoptosis): removing damaged or unnecessary neurons
  • Functional reorganization: reassigning cognitive functions to different brain areas.

Neuroscience Methods

  • Direct interventional studies include alterations of brain function (e.g., drugs, lesions, stimulation)
  • Indirect measurements include examining brain tissue, metabolites, and neuroimaging to understand neural function—including in vivo and post-mortem analyses.
  • Neuropsychological assessments use tests and tasks to study brain functions related to behaviour and cognitive ability.

Levels of Explanation

  • To understand a disorder, it's better to consider different levels (e.g. social, psychological, cognitive, and biological), not consider them mutually exclusive.

Disciplines

  • Neuroscience has multiple overlapping specializations with varying emphases
  • Examples include computational neuroscience, cognitive neuropsychiatry, and neuropsychopharmacology.

Neurobiology

  • Neurobiology focuses on the molecular and cellular interactions within the nervous system
  • Neurobiology studies neuronal signaling, cell physiology, and genetics. Includes natural and artifical interventions & pathologies.

Systems Neuroscience

  • Systems neuroscience examines neural networks as a whole. A range of scales, encompassing from interconnected neurons to larger brain circuits, are investigated in systems neuroscience.

Psychopharmacology

  • Psychopharmacology specifically investigates neuronal mechanisms by which substances influence the mental state by acting on neurochemicals.

Neuropsychology

  • Neuropsychology assesses the relationship between brain structure and function and human thoughts, feelings, and behaviour. It uses standardized tasks.

Cognitive Neuroscience

  • Cognitive neuroscience explores neural correlates of thoughts, emotions and behaviour using intervention techniques like transcranial magnetic stimulation as well as neuroimaging.

Computational Neuroscience

  • Computational neuroscience builds computer models of brain function to test theories.

Additional Information from the Text

  • Different types of neurons, including multipolar, pyramidal, Purkinje, bipolar, and unipolar neurons, exist.
  • Communication between neurons involves action potentials and neurotransmitters.
  • The brain is a network of networks.
  • The different uses of specific neurotransmitters and receptors in the brain's systems allows for drugs to selectively affect certain circuits, behaviors, and perceptual systems.
  • The hippocampus and similar areas are key in cognition and memory but are not exclusively dedicated to these tasks.
  • Various disciplines exist within neuroscience, emphasizing elements of a given system, like biological, cellular to larger-scale brain processes.
  • Specific examples, such as how SSRIs work and how dopamine receptor occupancy differs across antipsychotics. There is also specific example information relating to brain damage (hemispatial neglect) through a case study of drawings.

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Test your knowledge on the various functions of the brain, focusing on brain matter, neurotransmitters, and neural connections. This quiz covers key concepts in neuroscience, including synaptic plasticity, the role of the somatic nervous system, and the effects of certain drugs on brain activity. Challenge yourself with these thought-provoking questions!

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