Neuroscience: CNS Axis and Brain Regions
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Questions and Answers

What is the primary function of regional specialisation in the cerebral cortex?

  • To process sensory information
  • To enable asymmetry between brain hemispheres
  • To allow for functional segregation of cognitive tasks (correct)
  • To facilitate distributed networks
  • What is the term for the deficits in knowing or recognizing faces, resulting from damage to the cortex?

  • Agnosia
  • Prosopagnosia (correct)
  • Cerebral palsy
  • Hemiparesis
  • Which part of the brain is responsible for integrating sensory information from the spinal cord and other brain regions?

  • Midbrain
  • Hindbrain
  • Forebrain (correct)
  • Cerebellum
  • What is the term for the networks of neurons in the cortex that are distributed across different regions?

    <p>Distributed networks</p> Signup and view all the answers

    Which artist was known to have prosopagnosia?

    <p>Chuck Close</p> Signup and view all the answers

    What is the primary function of the autonomic system in the nervous system?

    <p>To control involuntary actions, such as heart rate and digestion</p> Signup and view all the answers

    What was a notable consequence of Phineas Gage's accident?

    <p>He experienced significant changes in his decision-making abilities</p> Signup and view all the answers

    What was the outcome of Eduardo Leite's accident?

    <p>He made a full recovery after the operation</p> Signup and view all the answers

    What was the purpose of the prefrontal leucotomy procedure?

    <p>To alleviate mental conflicts in patients</p> Signup and view all the answers

    What was a common trait observed in patients who underwent prefrontal leucotomy?

    <p>Apathetic and lethargic behavior</p> Signup and view all the answers

    Who is credited with performing the first prefrontal leucotomy?

    <p>Egas Moniz</p> Signup and view all the answers

    What was the outcome of Egas Moniz's work on prefrontal leucotomy?

    <p>He received a Nobel Prize for his work</p> Signup and view all the answers

    What is the primary function of the V4 region in the visual cortex?

    <p>Recognition of specific objects, including faces</p> Signup and view all the answers

    What is a characteristic of the organization of the cortex?

    <p>Regional specialization and distributed networks</p> Signup and view all the answers

    What is the main function of the default mode network?

    <p>None of the above</p> Signup and view all the answers

    What is the term for the areas of the brain that are active when a person is not focused on the outside world?

    <p>Default mode network</p> Signup and view all the answers

    What is the primary function of the dorsal attention network?

    <p>Executive control of attention</p> Signup and view all the answers

    What is the name of the technique used to study the resting state network?

    <p>Resting state functional MRI (RS-fMRI)</p> Signup and view all the answers

    What is the term for the low-frequency correlations observed in the resting state network?

    <p>Low-frequency correlations</p> Signup and view all the answers

    Which network is involved in decision-making?

    <p>Frontoparietal network</p> Signup and view all the answers

    What is the term for the visual cortex region involved in integrating vision with specific actions?

    <p>Dorsal and ventral streams</p> Signup and view all the answers

    How many leucotomy operations were performed in England and Wales between 1942 and 1954?

    <p>10,365</p> Signup and view all the answers

    What is the primary characteristic of the cerebral cortex, as described by its organization?

    <p>Regional specialization and distributed networks</p> Signup and view all the answers

    What is the term for the condition in which a person cannot read words seen in the left visual field?

    <p>Pure alexia</p> Signup and view all the answers

    Which brain region is responsible for integrating sensory information from the spinal cord and other brain regions?

    <p>Diencephalon</p> Signup and view all the answers

    What is the primary function of the corpus callosum?

    <p>Connecting the two hemispheres of the brain</p> Signup and view all the answers

    What is the term for the 'maps' found in primary sensory areas of the cerebral cortex?

    <p>Sensory homunculi</p> Signup and view all the answers

    What is the term for the phenomenon in which one hemisphere of the brain is dominant over the other?

    <p>Hemispheric lateralization</p> Signup and view all the answers

    What is the primary function of the cerebral cortex in relation to the rest of the nervous system?

    <p>Processing sensory information</p> Signup and view all the answers

    What is the term for the part of the brain that plays a crucial role in motor control and learning?

    <p>Cerebellum</p> Signup and view all the answers

    Which structure is responsible for integrating basal ganglia and cerebellar output?

    <p>Thalamus</p> Signup and view all the answers

    What is the primary function of the cerebellum?

    <p>Timing and error detection</p> Signup and view all the answers

    Which part of the brain is responsible for physiological homeostasis?

    <p>Hypothalamus</p> Signup and view all the answers

    What is the primary function of the midbrain?

    <p>Motor control of eye movement</p> Signup and view all the answers

    Which structure is involved in central pattern generation and coordinated movement?

    <p>Spinal cord</p> Signup and view all the answers

    What is the primary function of the autonomic nervous system?

    <p>Maintenance of metabolic homeostasis</p> Signup and view all the answers

    Which structure is involved in evaluating and updating metabolic and physiological processes?

    <p>Hypothalamus</p> Signup and view all the answers

    What is the primary function of the thalamus in sensation?

    <p>Integration of sensory information from the spinal cord and other brain regions</p> Signup and view all the answers

    Which structure is involved in learning and prediction, particularly through error calculation and motor learning?

    <p>Cerebellum</p> Signup and view all the answers

    What is the primary function of the cortex in terms of output?

    <p>Exclusive output to the spinal cord</p> Signup and view all the answers

    Study Notes

    Introduction to Functional Organisation of the Nervous System

    • The CNS axis consists of the spinal cord, hindbrain (medulla and pons), midbrain, forebrain (cortex, basal ganglia, and thalamus), and autonomic system.
    • The lecture is divided into three parts: the cerebral cortex, other brain regions and the spinal cord, and functional integration.

    Part 1: The Cerebral Cortex

    • Features of cortical organisation:
      • Regional specialisation
      • Distributed networks
      • Asymmetry
      • Maps
    • Regional specialisation:
      • Prefrontal cortex: decision making and executive function
      • Parietal cortex: sensation and spatial awareness
      • Temporal cortex: hearing and memory
      • Occipital cortex: vision
    • Distributed networks:
      • Networks are not limited to specific regions
      • Examples: default mode network, language network
    • Asymmetry:
      • Different functions are localised to different sides of the brain
      • Examples: language (left hemisphere), spatial awareness (right hemisphere)
    • Maps:
      • Primary visual cortex: maps visual information
      • Primary motor cortex: maps motor control

    Phineas Gage and Eduardo Leite

    • Phineas Gage: a famous case study of a man who suffered a brain injury that affected his personality and decision-making abilities
    • Eduardo Leite: a man who had an iron bar pierce his skull and brain, affecting his cognitive abilities

    Vision

    • Primary visual cortex: processes basic visual information
    • Dorsal and ventral streams:
      • Dorsal stream: "where" pathway, guides actions towards objects
      • Ventral stream: "what" pathway, recognises objects

    Language

    • Regional specialisation:
      • Language is localised to the left hemisphere
    • Distributed networks:
      • Language network involves multiple brain regions
    • Asymmetry:
      • Language is typically lateralised to the left hemisphere
    • Maps:
      • Language areas in the brain are organised topographically

    Part 2: Other Brain Regions and the Spinal Cord

    • Diencephalon:
      • Thalamus: relays sensory information to the cortex
      • Hypothalamus: regulates physiological homeostasis
    • Midbrain:
      • Cranial nerves III, IV: motor control of eye movement
      • Dopamine (substantia nigra): involved in reward and motivation
    • Cerebellum and hindbrain:
      • Cerebellum: coordinates movement and regulates timing
      • Pons: relays information to the cerebellum
      • Medulla: regulates basic functions such as breathing and swallowing
    • Spinal cord:
      • Processes sensory information and relays it to the brain
      • Regulates reflexes and autonomic functions

    Part 3: Functional Integration

    • Autonomic nervous system:
      • Parasympathetic nervous system: involved in relaxation and digestion
      • Sympathetic nervous system: involved in "fight or flight" responses
    • Metabolic regulation:
      • Hypothalamus: regulates energy metabolism, circadian rhythms, and reproductive behaviour
    • Learning and prediction:
      • Thalamus: involved in sensory processing and learning
      • Cerebellum: involved in motor learning and error calculation
      • Basal ganglia: involved in reward and salience processing

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    Description

    Understand the functional organisation of the central nervous system, including the autonomic system, spinal cord, hindbrain, cerebellum, midbrain, and forebrain, as well as the significance of regions and maps in the cortex.

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