Neuroscience: Chemistry of Memory and Energy
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Questions and Answers

What is typically referred to as the ability of biological systems to store and retrieve information, primarily at the molecular level?

Memory

What is the process by which a polypeptide chain acquires its functional three-dimensional structure from a linear sequence of amino acids?

Protein folding

What is a long-lasting increase in synaptic strength following high-frequency stimulation of a synapse?

Long term potentiation or LTP

Which two diseases are caused by insufficient and misfolded proteins?

<p>Parkinson's Disease</p> Signup and view all the answers

What is the process of creating glucose from non-carbohydrate sources, such as amino acids and lactate?

<p>Gluconeogenesis</p> Signup and view all the answers

What is involved in the final step of glycolysis, producing ATP?

<p>Pyruvate Kinase</p> Signup and view all the answers

What is essential for neurons to generate action potentials and release neurotransmitters, processes vital for brain cell communication?

<p>Glucose</p> Signup and view all the answers

What type of diet is rich in omega-3-fatty acids, antioxidants and whole grains, and can improve glucose metabolism, reduce inflammation and enhance cognitive function?

<p>Mediterranean diet</p> Signup and view all the answers

What catalyzes the first step in glycolysis, trapping glucose in the cell?

<p>Hexokinase</p> Signup and view all the answers

What is a long, thin fiber that carries electrical signals away from the cell body?

<p>Axon</p> Signup and view all the answers

What is the primary role of neurotransmitters in the body?

<p>To transmit messages from neurons to muscles.</p> Signup and view all the answers

What process allows neurotransmitters to be reabsorbed back into the presynaptic neuron?

<p>Reuptake</p> Signup and view all the answers

What is a natural chemical produced by the brain, also known as gamma-aminobutyric acid?

<p>GABA</p> Signup and view all the answers

Foods like salmon, turkey and tofu are rich in tryptophan, which helps produce which neurotransmitter?

<p>Serotonin</p> Signup and view all the answers

What is also known as the "stress hormone"?

<p>Cortisol</p> Signup and view all the answers

Which two hormones are released along with cortisol, and play a role in the body's immediate response?

<p>Norepinephrine</p> Signup and view all the answers

What disorder is characterized by long-term overproduction of cortisol, unrelated to stress?

<p>Cushing's Syndrome</p> Signup and view all the answers

What condition occurs when the adrenal glands don't produce enough cortisol and aldosterone?

<p>Addison's Disease</p> Signup and view all the answers

What is DNA primarily responsible for?

<p>Carrying genetic information for an organism's development and functioning.</p> Signup and view all the answers

In the context of gene-environment interaction, what does "nurture" refer to?

<p>The influence of learning, life experiences, and environment after birth.</p> Signup and view all the answers

What is epigenetics?

<p>The study of changes in gene expression that do not alter the DNA sequence.</p> Signup and view all the answers

Which process involves adding a methyl group to DNA to suppress gene activity?

<p>DNA methylation</p> Signup and view all the answers

How does transgenerational epigenetics impact future generations?

<p>By inheriting chemical changes in gene expression.</p> Signup and view all the answers

What is produced by the pineal gland in response to darkness, helping to regulate the sleep-wake cycle by signaling to the body that it's time to sleep?

<p>Melatonin</p> Signup and view all the answers

What promotes cortical arousal and desynchrony, which are essential for the brain's activity during REM sleep?

<p>Acetylcholine</p> Signup and view all the answers

What are the effects on mental health if melatonin production is disrupted?

<p>All of the above</p> Signup and view all the answers

What is a chronic condition where individuals compulsively seek and use substances, despite harmful consequences?

<p>Addiction</p> Signup and view all the answers

Which neurotransmitter is most associated with the brain's reward system and is heavily impacted by drug use?

<p>Dopamine</p> Signup and view all the answers

Chronic use of alcohol can disrupt the body's ability to process which main energy source for the brain?

<p>Glucose</p> Signup and view all the answers

How does opioid use (like heroin) impact brain cell function?

<p>It disrupts mitochondrial function, leading to lower energy for brain cells.</p> Signup and view all the answers

Which neurotransmitter is linked to mood, cravings, and can be affected by drugs like ecstasy?

<p>Serotonin</p> Signup and view all the answers

What are some examples of environmental factors that can affect brain health?

<p>All of the above</p> Signup and view all the answers

What is a developmental disorder affecting communication and behavior, often associated with neurochemical and structural brain differences?

<p>Autism Spectrum Disorder (ASD)</p> Signup and view all the answers

What is a major component of cell membranes, playing a crucial role in regulating membrane fluidity and synaptogenesis?

<p>Cholesterol</p> Signup and view all the answers

Unlike polysaccharides, proteins and nucleic acids, what cannot form polymers?

<p>Lipids</p> Signup and view all the answers

What type of fat contains omega-3 and omega-6 fatty acids?

<p>Good fat</p> Signup and view all the answers

What is water-soluble and effective in scavenging ROS in the brain's aqueous environment?

<p>Ascorbic acid</p> Signup and view all the answers

Which neurotransmitter precursor plays a significant role in improving attention, understanding and memory?

<p>Acetylcholine</p> Signup and view all the answers

Which neurotransmitter precursor is naturally found in foods high in protein?

<p>Glutamate</p> Signup and view all the answers

What is an excitatory neurotransmitter that prepares the body for the fight and flight response?

<p>Epinephrine</p> Signup and view all the answers

What neurotransmitter is secreted from brainstem neurons and nerves, internalizing the gastrointestinal tract?

<p>Serotonin</p> Signup and view all the answers

What neurotransmitter can affect several areas of the brain systematically, modulating thinking, feeling, and action?

<p>Dopamine</p> Signup and view all the answers

What does the gut-brain axis represent?

<p>The communication network linking the gut and the brain.</p> Signup and view all the answers

What are the neurotransmitters produced by the gut?

<p>Both A and B</p> Signup and view all the answers

What are the signs of poor gut health?

<p>All of the above</p> Signup and view all the answers

What are serotonin, dopamine and ghrelin examples of?

<p>Neurotransmitters</p> Signup and view all the answers

Which health condition is linked to the gut-brain axis?

<p>All of the above</p> Signup and view all the answers

What is a progressive disease that affects motor neurons, resulting in muscle weakness and paralysis?

<p>Amyotrophic lateral sclerosis</p> Signup and view all the answers

What are proteins that help speed up metabolism, or the chemical reactions in our bodies?

<p>Enzymes</p> Signup and view all the answers

What are enzymes that break down proteins?

<p>Proteolytic enzymes</p> Signup and view all the answers

What helps to maintain the body's redox balance and protect against oxidative stress?

<p>Antioxidant enzymes</p> Signup and view all the answers

What are diverse conditions characterized by selective dysfunction and ongoing loss of neurons, glial cells, and the neural networks in the brain and spinal cord?

<p>Neurodegenerative diseases</p> Signup and view all the answers

What is a group of hormones that belong to the class of chemical compounds known as steroids?

<p>Steroid hormone</p> Signup and view all the answers

What refers to the wide array of behaviors and actions one can display that can result in emotional, mental, or physical harm to a person?

<p>Aggression</p> Signup and view all the answers

What are chemicals that coordinate different functions in the body by carrying messages through the blood to your organs, skins, muscles, and other tissues?

<p>Hormones</p> Signup and view all the answers

What region in the brain processes emotions like fear and aggression?

<p>Amygdala</p> Signup and view all the answers

What can chronic stress lead to, affecting mood, memory, and immune function?

<p>Cortisol and stress</p> Signup and view all the answers

What helps us understand how substances like alcohol, nicotine, and drugs affect brain biochemistry?

<p>Understanding how substances like alcohol, nicotine, and drugs affect brain biochemistry</p> Signup and view all the answers

What is the primary marker for diabetes, indicating blood sugar levels?

<p>Glucose</p> Signup and view all the answers

What is a disorder characterized by reduced levels of brain-derived neurotrophic factor (BDNF) and serotonin, often associated with depression?

<p>Major depressive disorder</p> Signup and view all the answers

What can plasma drug levels predict, indicating whether a patient is receiving an effective dose or experiencing toxicity?

<p>Antidepressants</p> Signup and view all the answers

Study Notes

The Chemistry of Memory

  • Memory is the ability of biological systems to store and retrieve information.
  • Protein folding is the process where a polypeptide chain acquires its three-dimensional structure.
  • Long-term potentiation (LTP) is a long-lasting increase in synaptic strength.
  • Alzheimer's disease and Parkinson's disease are examples of diseases caused by insufficient and misfolded proteins.

The Brain's Energy Currency

  • Gluconeogenesis is the process of creating glucose from non-carbohydrate sources.
  • Pyruvate kinase is involved in the final step of glycolysis, producing ATP.
  • Glucose is essential for neurons generating action potentials and releasing neurotransmitters, crucial for brain cell communication.
  • omega-3 fatty acids, antioxidants, and whole grains improve glucose metabolism, reduce inflammation, and enhance cognitive function.

Neurotransmitters: The Body's Chemical Messengers

  • Axons are long, thin fibers that carry electrical signals away from the cell body.
  • Neurotransmitters transmit messages from neurons to muscles.
  • Reuptake is the process of reabsorbing neurotransmitters back into the presynaptic neuron.
  • GABA is a natural chemical produced by the brain.
  • Serotonin is produced from tryptophan, found in foods like salmon, turkey, and tofu.

Stress and Cortisol

  • Cortisol is the "stress hormone."
  • Adrenaline and norepinephrine play a role in the body's immediate response to stress.
  • Cushing's syndrome is a disorder characterized by long-term cortisol overproduction, unrelated to stress.

DNA, Genes, & Behaviour

  • DNA carries genetic information crucial for development and functioning.
  • Nurture refers to learning, life experiences, and environment after birth in gene-environment interactions.
  • Epigenetics studies changes in gene expression without altering the DNA sequence.
  • DNA methylation is a process involving adding a methyl group to DNA to regulate gene activity.
  • Transgenerational epigenetics means inheriting chemical changes in gene expression through future generations.

Sleep, Dreams, and Biochemistry

  • Melatonin is a hormone produced by the pineal gland that regulates the sleep-wake cycle.
  • Acetylcholine promotes cortical arousal and desynchrony, essential for REM sleep.
  • Mood disorders, sleep quality, and seasonal affective disorder (SAD) can be impacted by disrupted melatonin production.

The Biochemical Basis of Addiction

  • Addiction is a chronic condition where individuals compulsively seek and use substances.
  • Dopamine is a neurotransmitter strongly connected to the brain's reward system.
  • Chronic alcohol use can disrupt the brain's glucose processing.
  • Opioid (like heroin) use disrupts mitochondrial function, leading to lower brain cell energy.
  • Serotonin is affected by drugs like ecstasy, influencing mood and cravings.

The Gut-Brain Connection

  • The gut-brain axis represents the communication network connecting the gut and the brain.
  • The gut produces neurotransmitters like serotonin and GABA.

Antioxidants and Brain Health

  • Ascorbic acid is a water-soluble antioxidant that scavanges harmful reactive oxygen species (ROS) in the brain.
  • Reactive oxygen species (ROS) are unstable molecules that react with other molecules, damaging cells.
  • Antioxidants counteract these unstable molecules.

Enzymes and Neurodegenerative Diseases

  • Amyotrophic lateral sclerosis (ALS) affects motor neurons.
  • Amygdala is a region of the brain that processes emotions like fear and aggression.
  • Enzymes are proteins that speed up metabolic reactions.
  • Proteolytic enzymes break down proteins.
  • Antioxidants play a role in reducing oxidative damage and protecting brain cells.

Addiction and Substance Abuse

  • Addictive behaviors stem from factors like imbalances in neurotransmitters and stress response.
  • Blood glucose levels (measured by glucose levels) are a key indicator of diabetes.
  • BDNF (brain-derived neurotrophic factor) and serotonin are connected to depression.
  • Antidepressants can be used to treat a variety of conditions including severe depression.

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Description

Explore the intricate relationship between chemistry and neuroscience in this quiz. Delve into the processes of memory creation, energy production in the brain, and the role of neurotransmitters in communication. Test your understanding of these fundamental concepts affecting brain function and health.

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