Neuroscience Chapter Overview

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Questions and Answers

The size of the ___________________ and ___________________ explains how we can be extremely expressive in our facial expressions.

frontal lobe, temporal lobe

Which of the following is NOT a function of the parietal lobe?

  • Processing of sensory information
  • Storage of auditory information (correct)
  • Integration of visual stimuli
  • Somatic sensory processing

The primary visual cortex receives input exclusively from the auditory system.

False (B)

What are the two important functional areas found in the occipital lobe?

<p>Primary visual cortex and visual association cortex</p> Signup and view all the answers

Match the following areas of the brain with their respective functions:

<p>Wernicke area = Language comprehension Primary somatic sensory area = Sensory information processing Primary visual cortex = Visual information reception Visual association cortex = Interpretation of visual stimuli</p> Signup and view all the answers

The sensory association area will ____________________________ the processing of sensory information coming to the primary sensory area.

<p>enhance</p> Signup and view all the answers

Which of the following is a function of the temporal lobe?

<p>Comprehension of language (D)</p> Signup and view all the answers

What are the three important functional areas of the temporal lobe?

<p>Auditory cortex, Wernicke area, hippocampus</p> Signup and view all the answers

The hypothalamus maintains _______________________________________ by ensuring that every internal organ system works individually, appropriately, and together.

<p>homeostasis</p> Signup and view all the answers

Which of the following regulates the release of hormones that reinforce the effects of sympathetic outflow?

<p>Hypothalamus (A)</p> Signup and view all the answers

The midbrain is also known as the mesencephalon.

<p>True (A)</p> Signup and view all the answers

What are the three main parts of the midbrain?

<p>Tectum, Tegmentum, Cerebral peduncle</p> Signup and view all the answers

Match the following parts of the corpora quadrigemina with their functions:

<p>Superior colliculi = Receive visual information Inferior colliculi = Receive auditory information Tectum = Part of the midbrain involved in sensory processing</p> Signup and view all the answers

The tegmentum is engaged in the regulation of ___________________ behaviors.

<p>motor</p> Signup and view all the answers

What neurotransmitter is critical in the synthesis within the substantia nigra?

<p>Dopamine (D)</p> Signup and view all the answers

What are the two nuclei of the midbrain?

<p>Red nucleus, Substantia nigra</p> Signup and view all the answers

Which part of the hindbrain is responsible for controlling balance and posture?

<p>Cerebellum (C)</p> Signup and view all the answers

The pons transmits information from the cerebellum to the spinal cord.

<p>False (B)</p> Signup and view all the answers

What structures make up the hindbrain?

<p>Cerebellum, pons, medulla oblongata</p> Signup and view all the answers

The limbic system is involved in primitive regulation of ____________________________ response.

<p>emotional</p> Signup and view all the answers

The ____________________________ is continuous with the spinal cord.

<p>medulla oblongata</p> Signup and view all the answers

Match the following structures to their functions:

<p>Cerebellum = Balance and posture control Pons = Regulates respiration Medulla oblongata = Controls heart rate Brainstem = Connects brain to spinal cord</p> Signup and view all the answers

What is the part of the brain responsible for thermoregulation?

<p>Hypothalamus (D)</p> Signup and view all the answers

The extremities are generally warmer than the core organs of the body.

<p>False (B)</p> Signup and view all the answers

What reflexes does the medulla oblongata control?

<p>Respiratory reflexes (B)</p> Signup and view all the answers

The cingulate cortex is responsible for regulating sensations of ____________________________.

<p>emotion</p> Signup and view all the answers

What are the two major ways the body produces heat?

<p>Chemical thermogenesis and shivering thermogenesis</p> Signup and view all the answers

The center of control for thermoregulation is the _______________________________ of the diencephalon.

<p>hypothalamus</p> Signup and view all the answers

The limbic system is an extension of the cerebellum.

<p>False (B)</p> Signup and view all the answers

Which hormone is released by the hypothalamus to influence heat production?

<p>Thyrotropin-releasing hormone (B)</p> Signup and view all the answers

Match the following terms with their descriptions:

<p>Hypothalamus = Regulates body temperature Shivering thermogenesis = Heat production via muscle activity Chemical thermogenesis = Heat produced through metabolic processes Limbic system = Involved in emotional response</p> Signup and view all the answers

What is the biological optimal range of body temperature for humans?

<p>Approximately 36.1°C to 37.2°C (97°F to 99°F)</p> Signup and view all the answers

Peripheral __________________________ = shunts blood from skin to core.

<p>vasoconstriction</p> Signup and view all the answers

What is the primary result of EPI release during thermogenesis?

<p>Increased heat production (B)</p> Signup and view all the answers

The chronic phase of the febrile response causes muscle catabolism and hyperglycemia.

<p>True (A)</p> Signup and view all the answers

What is a benefit of moderate fever?

<p>It kills many microbes by raising body temperature.</p> Signup and view all the answers

Which of the following is NOT a phase of the febrile response?

<p>Crisis Phase (D)</p> Signup and view all the answers

Hyperthermia can cause _______________________ damage.

<p>cellular</p> Signup and view all the answers

Match the term with its description:

<p>Vasodilation = Increases blood flow to the skin Hyperthermia = Excessive body temperature not controlled by the body Anorexia = Loss of appetite Hypothermia = Abnormally low body temperature</p> Signup and view all the answers

What occurs in the body during accidental hypothermia?

<p>Heat cramps and loss of electrolytes.</p> Signup and view all the answers

The anterior pituitary then releases _____________________ which stimulates the release of _____________________ from the _____________________ gland.

<p>TSH, T4, thyroid</p> Signup and view all the answers

Which mechanism is NOT a method of heat loss?

<p>Increased muscle tone (B)</p> Signup and view all the answers

Fever can be triggered by both exogenous and endogenous pyrogens.

<p>True (A)</p> Signup and view all the answers

What physiological response is fever primarily aimed at addressing?

<p>Infection</p> Signup and view all the answers

The initial trigger for fever is an __________________________, usually a __________________________ from the outer membrane of __________________________.

<p>exogenous pyrogen, lipopolysaccharide, bacteria</p> Signup and view all the answers

Which hormone acts on the preoptic/anterior hypothalamus to regulate body temperature?

<p>Prostaglandins (D)</p> Signup and view all the answers

Match the following mechanisms with their purpose:

<p>Radiation = Heat loss through electromagnetic waves Conduction = Heat transfer through direct contact Convection = Heat loss through air or water movement Evaporation = Heat loss through phase change of water</p> Signup and view all the answers

What response is described as covering up the body surface to prevent heat loss?

<p>Conservation response</p> Signup and view all the answers

Flashcards

What explains our expressive facial expressions?

The size of the motor cortex and the sensory cortex explains our ability to create a large variety of facial expressions.

What does the parietal lobe do?

The parietal lobe is responsible for processing, integrating, and storing sensory information. It also processes the sensory information that comes from the primary sensory area, which is the final destination for sensory input.

Where does sensory information go?

The primary somatic sensory area is the final destination for sensory information. It receives sensory input from the body, including touch, temperature, pain, and pressure.

What part of the brain receives visual information?

The primary visual cortex receives input from the eyes. It is the first area in the brain that processes visual information.

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What is the visual association cortex responsible for?

The visual association cortex is involved in the recognition and interpretation of visual information. It helps us to understand what we are seeing.

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What does the Wernicke area do?

The Wernicke area is responsible for the comprehension and production of speech. Damage to this area can lead to aphasia, which is an inability to speak or a speech dysfunction.

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What is the temporal lobe involved in?

The temporal lobe is involved in long-term memory and the secondary processing of information from the senses of hearing, smell, and taste.

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Where is the temporal lobe located?

The temporal lobe lies below the parietal lobe.

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What is the role of the hypothalamus?

The hypothalamus is a part of the brain that regulates many essential functions of the body.

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What does the hypothalamus regulate?

The hypothalamus regulates body temperature, hunger, thirst, and sleep-wake cycles.

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What is the midbrain?

The midbrain is a part of the brainstem that connects the forebrain to the hindbrain. It has several important structures.

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What is the corpora quadrigemina?

The corpora quadrigemina are two pairs of bumps on the dorsal surface of the midbrain. They are involved in visual and auditory reflexes.

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What does the superior colliculi do?

The superior colliculi receive visual, auditory, and somatosensory information to help us orient our head and focus our attention.

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What does the inferior colliculi do?

The inferior colliculi receive auditory information and relay it to the temporal lobe for processing.

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What is the tegmentum?

The tegmentum is a collection of neurons in the midbrain that regulate motor and sensory functions.

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What is the substantia nigra?

The substantia nigra is a part of the midbrain that is involved in the production of dopamine. It is implicated in Parkinson's disease.

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What are the main parts of the hindbrain?

The hindbrain is responsible for basic life functions like breathing, heart rate, and sleep cycles. It consists of the cerebellum, pons, and medulla oblongata.

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What reflexes does the medulla oblongata control?

The medulla oblongata is the lowest part of the brainstem and controls vital reflexes such as breathing, heart rate, and blood pressure.

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What does the cerebellum do?

The cerebellum integrates sensory information, especially from the body, to control balance, posture, and coordination.

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What are the structures in the Limbic System?

The limbic system is a group of structures in the brain that is involved in emotions, memory, and motivation. It includes the amygdala, hippocampus, hypothalamus, and cingulate gyrus.

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What does the cingulate cortex do?

The cingulate gyrus is part of the limbic system and helps regulate emotions and form responses to sensory information.

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What is the hippocampus involved in?

The hippocampus is a part of the limbic system that is involved in long-term memories, especially those related to events and experiences.

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What makes up the brainstem?

The brainstem connects the cerebrum to the spinal cord and is responsible for basic life functions and reflexes. It consists of the midbrain, pons, and medulla oblongata.

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What is the reticular formation?

The reticular formation is a network of neurons in the brainstem that regulates arousal, sleep, and other autonomic functions.

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What is the limbic system?

The limbic system is a brain structure involved in regulating instinctive responses, visceral reactions, and emotional behaviors. It also plays a role in biological drives and our sense of self.

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What does the limbic system regulate?

The limbic system regulates the fight or flight response, a primitive survival mechanism that prepares the body for immediate action.

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What else does the limbic system control?

The limbic system controls visceral reactions such as heart rate and respiration, which happen unconsciously and are important for bodily functions.

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How does the limbic system affect behavior?

The limbic system manages emotional behaviors like anger, fear, and happiness, influencing how we express and experience our feelings.

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What are some biological drives regulated by the limbic system?

The limbic system plays a crucial role in biological drives, including hunger, thirst, and sex, essential for survival and reproduction.

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What does the limbic system influence?

The limbic system contributes to our sense of self, including our personality, identity, and individual experiences.

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Where is the temperature regulation center located?

The hypothalamus is the brain region responsible for thermoregulation, maintaining a stable internal temperature. This involves balancing heat production, heat loss, and heat gain.

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What is the body's optimal temperature range?

The body has a narrow range of optimal temperature. Internal organ temperatures vary, with extremities being colder than the core and the rectum being warmer than the skin surface.

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Fever

The body's response to infection or tissue damage, resulting in an increase in core body temperature.

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Anti-pyrogens / Cytokines

Chemicals that help to lower the body temperature during a fever.

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Acute phase of fever

This phase of a fever is characterized by symptoms like loss of appetite, fatigue, and sleepiness due to the release of inflammatory chemicals.

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Chronic phase of fever

This phase of a fever involves longer-term effects like muscle breakdown, increased blood sugar, and immune system activation.

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Negative Feedback Mechanisms

This process helps to control the magnitude of a fever, preventing it from becoming excessively high.

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Hyperthermia

An abnormally high body temperature that is not caused by the body's internal temperature control system (hypothalamus).

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Heat Cramps

Severe muscle cramps that occur after prolonged exercise or strenuous activity in hot environments, often due to fluid and electrolyte loss.

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Hypothermia

A decrease in body temperature below the normal range, often caused by prolonged exposure to cold temperatures.

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What is the sequence of hormone release in the thyroid hormone feedback loop?

The anterior pituitary gland releases Thyroid Stimulating Hormone (TSH), which then triggers the release of Thyroxine (T4) from the thyroid gland. T4 acts on the hypothalamus, stimulating the release of Epinephrine (EPI).

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How does Epinephrine contribute to heat production?

Epinephrine increases heart rate, promotes vasoconstriction, and increases metabolic rate, leading to increased body heat production.

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What are the mechanisms of heat loss?

Radiation, conduction, convection, evaporation, increased respiration, voluntary stretching movements, peripheral vasodilation, decreased muscle tone, and adaptation to warmer climates.

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What are the mechanisms of heat conservation?

Vasoconstriction and behavioral responses such as covering the body surface to minimize heat loss.

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What are other names for fever?

Fever is also known as pyrexia or hyperthermia.

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Why does a fever occur?

Fever is a physiological response to an infection, aiming to reduce the effects of the invading organism.

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How is the body's thermoregulatory set point affected during fever?

Fever involves resetting the thermoregulatory set point in the hypothalamus, triggered by exogenous or endogenous pyrogens.

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Explain the role of exogenous pyrogens in fever development?

Exogenous pyrogens, primarily lipopolysaccharide (LPS), are produced by invading organisms, often from the outer membrane of bacteria and viruses. These pyrogens stimulate the release of endogenous pyrogens.

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Study Notes

Embryologic Origin of the Brain

  • The brain begins as a hollow tube
  • At early stages, there are 3 vesicles that develop into 5 vesicles
  • The vesicles are telencephalon, diencephalon, midbrain, mesencephalon, metencephalon, and myelencephalon

Adult Brain Divisions

  • The three main divisions are the forebrain, midbrain, and hindbrain

Forebrain Divisions

  • The two main parts of the forebrain are the telencephalon and diencephalon
  • The telencephalon consists of the cerebral cortex and basal ganglia

Cerebral Cortex

  • The cerebral cortex is composed entirely of gray matter
  • It has many layers of neurons with different morphologies

Convolutions (Ridges) and Grooves

  • The ridges are called gyri, and the grooves are called sulci
  • The central sulcus separates the frontal and parietal lobes
  • The lateral sulcus separates the frontal and temporal lobes

Frontal Lobe - Functional Areas

  • The four important functional areas are the prefrontal area, premotor area, primary motor area, and Broca's motor speech area
  • Prefrontal area controls goal-oriented behavior, memory, and emotional decision making
  • Broca's area controls speech production
  • The premotor area programs muscle movements

Primary Motor Area and Homunculus

  • The primary motor area is responsible for voluntary muscle movement
  • The homunculus in the primary motor cortex shows the amount of motor neurons dedicated to specific body parts: larger regions for areas like hands and mouth, indicating their greater control

Parietal Lobe - Functional Areas

  • The two important functional areas are the primary sensory cortex and sensory association area.
  • The sensory association area processes incoming sensory information.
  • Primary sensory cortex receives information from various sensory receptors.

Occipital Lobe - Functional Areas

  • The two important functional areas are the primary visual cortex and visual association cortex
  • The primary visual cortex receives info from the retina
  • The visual association cortex processes the sensory info of the retina.

Temporal Lobe - Functional Areas

  • The three important functional areas are Wernicke's area, primary auditory cortex, and auditory association cortex
  • Wernicke's area is for language comprehension; if damaged aphasia or speech dysfunction can occur.
  • The auditory cortex processes auditory information
  • The auditory association cortex interprets sounds

Corpus Callosum

  • The corpus callosum connects the two cerebral hemispheres for communication
  • It allows for the coordinated activity between the two hemispheres

Basal Ganglia

  • The four main structures are the corpus striatum, amygdala, subthalamic nucleus, and substantia nigra
  • Corpus striatum contains the lentiform nucleus, putamen, and globus pallidus
  • These structures are involved in fine tuning motor movements

Diencephalon

  • The parts of the diencephalon are the thalamus, epithalamus and hypothalamus
  • The epithalamus contains the pineal gland which produces melatonin
  • The thalamus is the major sensory relay center.
  • The hypothalamus regulates homeostasis and hormone release

Midbrain

  • The three main parts are the corpora quadrigemina, tegmentum, and basis pedunculi (cerebral peduncle)
  • The corpora quadrigemina consists of superior and inferior colliculi, involved in visual and auditory processing

Hindbrain

  • The main parts are the pons, medulla oblongata, and cerebellum
  • Medulla oblongata is continuous with the spinal cord
  • Cerebellum coordinates movement/balance
  • Pons regulates respiration and relays info to the cerebellum
  • Medulla oblongata controls reflexes like heart rate, blood pressure, and respiration

Brainstem

  • The brainstem is the midbrain, pons, and medulla oblongata.
  • Reticular formation is a system of neurons responsible for many autonomic reflexes.

Limbic System

  • The Limbic system is associated with emotions, memory, and behavior
  • Its structures include the cingulate cortex, hippocampus, and amygdala.
  • This system is considered an extension of the hypothalamus, modifying or extending its influence on behavior.

Temperature Regulation

  • The hypothalamus is responsible for thermoregulation
  • Balancing heat production and loss
  • Body temperature maintained at an optimal range
  • Thermoreceptors on the skin and in the core send information to the hypothalamus
  • Two ways to produce heat: chemical thermogenesis & shivering thermogenesis
  • Heat loss through radiation, conduction, convection
  • Physiological mechanisms to adapt to temperature changes (vasoconstriction etc)

Fever

  • Fever is a physiological response to an infection
  • The hypothalamus modifies its set point to increase body temperature
  • This is due to releasing endogenous pyrogens which act directly on the hypothalamus
  • Fever is also known as the febrile response or pyrexia or the inflammatory response

Hyperthermia and Hypothermia

  • Hyperthermia is an increase in body temperature not related to an infection
  • Causes can be due to strenuous exercise or environmental factors like high temperature
  • Hypothermia is a decrease in core body temperature often due to prolonged exposure to cold temperatures or severe trauma.
  • Causes can be immersion in cold water, certain medical conditions or environmental factors like cold temperatures

Trauma Induced Temperature Change

  • Any injury affecting the CNS can result in fever.
  • This is usually from increased intracranial pressure (ICP), bleeding or inflammation.
  • The body's reaction is sustained and unaffected by anti-pyretic drugs.
  • Trauma can lead to elevation or decrease in body temperature.

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