Neuroscience Chapter on Brain Regions and Cells
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Questions and Answers

Which Brodmann area is associated with the premotor area?

  • Area 6 (correct)
  • Area 44
  • Area 41
  • Area 4
  • Damage to Broca's area, typically located in the left hemisphere, can result in which condition?

  • Receptive aphasia
  • Auditory processing deficits
  • Expressive aphasia (correct)
  • Visual agnosia
  • Which of the following functions is NOT typically associated with the prefrontal area?

  • Short-term memory
  • Goal-oriented behavior
  • Inhibition of the limbic area
  • Primary motor control (correct)
  • What is the primary function of astrocytes within the central nervous system (CNS)?

    <p>Providing rapid transport for nutrients and metabolites and forming part of the blood-brain barrier. (B)</p> Signup and view all the answers

    The primary motor area exhibits somatotopic organization, often represented by a:

    <p>Homunculus (D)</p> Signup and view all the answers

    In what lobe of the brain would you find the somatic sensory input areas?

    <p>Parietal lobe (B)</p> Signup and view all the answers

    Which type of glial cell is responsible for myelin production in the peripheral nervous system (PNS)?

    <p>Schwann cells (D)</p> Signup and view all the answers

    Which cells phagocytize the remnants of the axon terminal after injury?

    <p>Macrophages and Schwann cells (B)</p> Signup and view all the answers

    Approximately how long after injury do new terminal sprouts project from the proximal segment of an axon?

    <p>7-14 days after injury (B)</p> Signup and view all the answers

    Where is the area responsible for processing auditory information located?

    <p>Temporal lobe (B)</p> Signup and view all the answers

    What is the role of microglia in the central nervous system (CNS)?

    <p>Immune defense and removal of cellular debris. (B)</p> Signup and view all the answers

    What is the approximate rate of nerve regeneration in the PNS?

    <p>1 mm/day (C)</p> Signup and view all the answers

    What is the function of ependymal cells in the central nervous system (CNS)?

    <p>To line ventricles and choroid plexuses and aid in CSF production. (B)</p> Signup and view all the answers

    Damage to the primary motor area results in contralateral control deficits. What does 'contralateral control' mean?

    <p>Control of the opposite side of the body (B)</p> Signup and view all the answers

    What is one of the main reasons for limited axon regeneration within the CNS in comparison to the PNS?

    <p>Increased incidence of glial scar formation (D)</p> Signup and view all the answers

    Which specific area is responsible for controlling eye movement in the frontal lobe?

    <p>Middle frontal gyrus (D)</p> Signup and view all the answers

    Mature neurons in the central nervous system (CNS) respond to injury in what way?

    <p>Permanent loss of the damaged cells. (C)</p> Signup and view all the answers

    Which change occurs in the axon terminal during Wallerian degeneration?

    <p>The axon terminal swells and degenerates, losing contact with the postsynaptic membrane. (A)</p> Signup and view all the answers

    Which type of nerve injury typically allows for more complete recovery?

    <p>Crushing injury (D)</p> Signup and view all the answers

    Why do peripheral nerves injured close to the spinal cord recover poorly and slowly?

    <p>Longer distance between the cell body and the peripheral termination of the axon (D)</p> Signup and view all the answers

    During axonal reaction, what is the fate of Nissl bodies within the cell body?

    <p>They are lost (chromatolysis). (B)</p> Signup and view all the answers

    What is the direction of conduction for afferent nerve fibers?

    <p>Toward the brain. (B)</p> Signup and view all the answers

    What is the main function of the olfactory nerve?

    <p>Carries impulses for the sense of smell (C)</p> Signup and view all the answers

    What forms a column or tube, enclosed by the original basal lamina of the endoneurium?

    <p>Schwann cells (C)</p> Signup and view all the answers

    Which structure synthesizes dopamine in the midbrain?

    <p>Substantia nigra (B)</p> Signup and view all the answers

    Dysfunction of dopaminergic neurons in the substantia nigra is associated with which of the following diseases?

    <p>Parkinson's disease and schizophrenia (A)</p> Signup and view all the answers

    The cerebral aqueduct connects which ventricles?

    <p>Third and fourth ventricles (B)</p> Signup and view all the answers

    Obstruction of the cerebral aqueduct can commonly cause which condition?

    <p>Hydrocephalus (C)</p> Signup and view all the answers

    Which of the following is a primary function of the cerebellum?

    <p>Reflexive, involuntary fine-tuning of motor control (A)</p> Signup and view all the answers

    Damage to the cerebellum typically affects motor coordination on which side of the body?

    <p>The same (ipsilateral) side (D)</p> Signup and view all the answers

    Which of the following structures transmits information from the cerebellum to the brainstem?

    <p>Pons (D)</p> Signup and view all the answers

    Which cranial nerves have nuclei located within the pons?

    <p>V-VIII (A)</p> Signup and view all the answers

    What can result from damage to the midbrain?

    <p>Difficulty with vision and hearing (C)</p> Signup and view all the answers

    Which cranial nerve dysfunction is associated with strabismus?

    <p>Oculomotor nerve dysfunction (B)</p> Signup and view all the answers

    Which part of the midbrain is primarily responsible for visual motor movements?

    <p>Superior colliculi (A)</p> Signup and view all the answers

    What area of the brain is primarily associated with processing visual information?

    <p>Occipital lobe (B)</p> Signup and view all the answers

    Which condition might be a symptom of midbrain dysfunction?

    <p>Dysregulation of body temperature (A)</p> Signup and view all the answers

    What cognitive functions are encompassed by awareness?

    <p>Self-awareness and mood awareness (B)</p> Signup and view all the answers

    Which area of the brain is primarily involved in executive functions such as planning and decision making?

    <p>Prefrontal cortex (B)</p> Signup and view all the answers

    What do the six extrinsic eye muscles allow for?

    <p>Gross eye movements (D)</p> Signup and view all the answers

    Where are the frontal eye fields located?

    <p>Middle frontal gyrus (A)</p> Signup and view all the answers

    Which function is NOT associated with the prefrontal cortex?

    <p>Heartbeat regulation (B)</p> Signup and view all the answers

    What is the role of the superior colliculi?

    <p>Control visual motor movements (B)</p> Signup and view all the answers

    Which muscle is NOT one of the six extrinsic eye muscles?

    <p>Gastric muscle (A)</p> Signup and view all the answers

    What is involved in the mediating of awareness?

    <p>Core attention networks and decisions (D)</p> Signup and view all the answers

    Flashcards

    Macrophages

    Cells that digest cellular debris in the nervous system after injury.

    Schwann cells

    Glial cells that support nerve regeneration by forming a tubular structure after injury.

    Retrograde changes

    Changes at the injured end of an axon affecting its function, extending to the next node of Ranvier.

    Axonal regeneration rate

    The process where axons regrow at approximately 1mm per day in the PNS.

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    Location of injury

    A key factor affecting nerve recovery; closer to the cell body means lower regeneration chances.

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    Type of injury

    Crushing injuries allow better recovery than cut injuries due to inflammatory response differences.

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    Glial scar formation

    A limiting factor in CNS regeneration, forming due to injury and inflammation.

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    Olfactory nerve function

    Carries sensory impulses for the sense of smell from olfactory epithelium to the brain.

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    Frontal Lobe

    Region of the brain responsible for goal-oriented behavior, memory, and concentration.

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    Prefrontal Area Functions

    Involves short term memory, thought elaboration, and inhibiting emotional responses.

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    Premotor Area

    Programs motor movements and controls eye movement using basal ganglia.

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    Primary Motor Area

    Controls voluntary motor function with somatotopic organization, including contralateral control.

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    Broca's Area

    Controls the motor aspect of speech and is involved in language processing.

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    Homunculus

    A map of the body's representation in the brain, particularly in the primary motor area.

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    Parietal Lobe

    Integrates sensory information, facilitating communication between motor and sensory areas.

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    Wernicke Area

    Involved in language comprehension, located in the temporal lobe.

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    Afferent Nerves

    Nerves that carry signals toward the brain or spinal cord.

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    Efferent Nerves

    Nerves that carry signals away from the brain or spinal cord.

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    Astrocytes

    CNS support cells that form blood-brain barrier and transport nutrients.

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    Oligodendrocytes

    CNS cells that form the myelin sheath around axons.

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    Chromatolysis

    A process of neuron cell body swelling and loss of Nissl bodies after injury.

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    Wallerian Degeneration

    Degeneration of the distal axon after injury that occurs in the PNS.

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    Awareness

    The content of thought encompassing self, environment, and emotions.

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    Cognitive functions

    Mental processes including attention, memory, and reasoning.

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    Executive attention networks

    Brain networks involved in reasoning, planning, and decision making.

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    Prefrontal cortex

    Brain area responsible for planning, evaluating outcomes, and self-control.

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    Goal-oriented behavior

    Ability to focus and work towards specific objectives.

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    Extrinsic eye muscles

    Six muscles that control gross eye movements.

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    Frontal eye fields

    Area controlling voluntary eye movements in the frontal lobe.

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    Superior colliculi

    Midbrain structures coordinating visual motor movements.

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    Red Nucleus

    Receives sensory information and sends motor signals to the cervical spinal cord.

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    Substantia Nigra

    A brain region that synthesizes dopamine; its dysfunction is linked to Parkinson’s and schizophrenia.

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    Cerebral Peduncles

    Fibers connecting the brain's cortex to the brainstem; involved in coordinating movement.

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    Cerebellum

    A brain region responsible for motor control, balance, and posture; operates ipsilaterally.

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    Aqueduct of Sylvius

    Carries cerebrospinal fluid (CSF) between the 3rd and 4th ventricles.

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    Pons

    A structure that transmits information between the cerebellum and brainstem, containing cranial nerve nuclei.

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    Motor Pathway

    Neural pathways that convey motor commands from the brain to the body.

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    Dopaminergic Neurons

    Neurons that produce dopamine; dysfunction affects mood and coordination.

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    Ocular movement tracking

    The ability of the eyes to follow moving objects in the visual field.

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    Cranial nerves involved

    The oculomotor, trochlear, and abducens cranial nerves control ocular movements.

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    Primary visual cortex

    Located in the occipital lobe (Brodmann area 17), it processes visual information from the retina.

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    Midbrain functions

    The midbrain coordinates motor and sensory pathways, including visual and auditory reflexes.

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    Corpora Quadrigemina

    A part of the midbrain responsible for visual and auditory reflexes; includes superior and inferior colliculi.

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    Study Notes

    Afferent and Efferent Nerves

    • Afferent nerves carry information toward organs or parts.
    • Efferent nerves carry information away from organs or parts.

    Neuron Structure

    • Unipolar neurons: Single axon and dendrite
    • Pseudounipolar neurons: Single axon that branches into two processes (one that goes to the CNS, one to a sensory receptor)
    • Bipolar neurons: Have one axon and one dendrite
    • Multipolar neurons: Multiple dendrites and one axon

    Support Cells of the Nervous System

    • Astrocytes: Form specialized contact, provide rapid transport, and are part of the blood-brain barrier.
    • Oligodendroglia: Formation of myelin sheath (CNS).
    • Microglia: Remove cellular debris (phagocytic).
    • Ependymal cells: Line ventricles and choroid plexuses (CSF production)
    • Schwann cells: Formation of myelin sheath (PNS)
    • Satellite glial cells: Surround neuron cell bodies, providing protection and promote cellular communication.

    CNS Regeneration

    • Mature neurons typically do not regenerate.
    • Myelinated fibers in the PNS can often repair.
    • Regeneration involves axonal reaction, removal of damaged tissue and Schwann cell regeneration.

    Nerve Regeneration

    • Speed and success depend on the location and type of injury (e.g., crush vs. cut).
    • Peripheral nerve injuries close to the spinal cord recover more slowly due to long distance.
    • Regenerating nerve tissues are guided by Schwann cells.

    Three Major Divisions of the Brain

    • Forebrain (prosencephalon): Includes telencephalon and diencephalon (thalamus and hypothalamus).
    • Midbrain (mesencephalon): located between the forebrain and hindbrain.
    • Hindbrain (rhombencephalon): Includes metencephalon (pons and cerebellum) and myelencephalon (medulla oblongata).

    Major Brain Structures

    • Cerebrum: Includes hemispheres, cerebral cortex, basal ganglia and rhinencephalon.
    • Cerebellum: Coordinates movement.
    • Brainstem: Includes midbrain, pons, and medulla oblongata; involved in relaying information and controlling vital functions.
    • Spinal cord: Pathway for nerve impulses between the brain and the body; connects with the brainstem.

    Other Key Concepts

    • Cranial nerves: 12 pairs of nerves from the brain, each with specific functions (sensory, motor, or mixed) and listed by number.
    • CSF (Cerebrospinal fluid): Produced by the choroid plexus; cushions and supports the brain and spinal cord. -Arachnoid villi: Reabsorb the CSF back into the blood circulation via a pressure gradient.
    • Blood supply to the brain: Vertebral and internal carotid arteries form the cerebral arterial circle of Willis; ensures adequate blood supply.
    • CSF circulation: Produced in the ventricles, travels to the subarachnoid space, and reabsorbed into the blood circulation.

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    Test your understanding of key concepts related to brain regions, their functions, and the role of glial cells in the central nervous system. This quiz covers topics including Brodmann areas, astrocytes, and myelin production. It's essential for students of neuroscience or anyone interested in neuroanatomy.

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