Neuroscience Chapter: Neurons and Action Potentials
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Questions and Answers

What unit is membrane potential measured in within the human body?

  • Volts
  • Kilovolts
  • Millivolts (correct)
  • Amps
  • A neuron is more positive on the inside of the cell, relative to the extracellular space around it.

    False (B)

    What is the name of the protein that straddles the membrane of the neuron, pumping potassium ions into the cell and sodium ions out?

    sodium-potassium pump

    Which of the following best describes voltage?

    <p>The measure of potential energy generated by separated charges (B)</p> Signup and view all the answers

    What is the typical resting membrane potential of a neuron?

    <p>-70 mV (B)</p> Signup and view all the answers

    Mechanically gated channels open in response to neurotransmitters.

    <p>False (B)</p> Signup and view all the answers

    What is the term for the flow of electricity from one point to another?

    <p>current</p> Signup and view all the answers

    When a neuron has a negative membrane potential, it is said to be ______.

    <p>polarized</p> Signup and view all the answers

    Match the following ion channels with their triggers:

    <p>Voltage-gated channels = Open at certain membrane potentials Ligand-gated channels = Open when a specific neurotransmitter latches on Mechanically gated channels = Open in response to physically stretching the membrane</p> Signup and view all the answers

    What is the fundamental way neurons communicate impulses?

    <p>By varying the frequency or number of electrical pulses. (D)</p> Signup and view all the answers

    Neurons can send signals at varying strengths and speeds to communicate different messages.

    <p>False (B)</p> Signup and view all the answers

    What is the name given to the nerve impulse fired by a neuron?

    <p>action potential</p> Signup and view all the answers

    What is the purpose of membranes in the context of electrical charges in the body?

    <p>To keep positive and negative charges separate until the energy is needed. (D)</p> Signup and view all the answers

    The human body maintains an overall negative electrical charge.

    <p>False (B)</p> Signup and view all the answers

    When a neuron is stimulated enough, it fires an ______ impulse.

    <p>electrical</p> Signup and view all the answers

    Match the following terms with their descriptions:

    <p>Neuron = A nerve cell that sends impulses Axon = The part of a neuron that transmits electrical impulses Action Potential = The electrical impulse that travels along a neuron Membrane = A barrier that separates electrical charges</p> Signup and view all the answers

    What happens after a neuron fires an electrical impulse?

    <p>It transmits the impulse down its axon to neighboring neurons. (C)</p> Signup and view all the answers

    What is the approximate voltage threshold (in mV) that must be reached for an action potential to be triggered?

    <p>-55 (C)</p> Signup and view all the answers

    During hyperpolarization, the membrane voltage briefly rises above the resting potential.

    <p>False (B)</p> Signup and view all the answers

    What is the term for the period when an axon cannot respond to another stimulus, regardless of its strength?

    <p>refractory period</p> Signup and view all the answers

    The rapid influx of ______ ions causes the cell to become massively depolarized during an action potential.

    <p>sodium</p> Signup and view all the answers

    Match the phase of action potential with what happens during that phase:

    <p>Depolarization = Sodium ions rush into the cell, making it more positive. Repolarization = Potassium ions flow out of the cell, attempting to rebalance the charges. Hyperpolarization = Membrane voltage drops below the resting potential. Resting State = All of the ion channels are closed, and the inner voltage is resting at -70 mV.</p> Signup and view all the answers

    Which of the following is MOST directly responsible for repolarization?

    <p>Opening of voltage-gated potassium channels (D)</p> Signup and view all the answers

    The strength of an action potential changes depending on the intensity of the stimulus.

    <p>False (B)</p> Signup and view all the answers

    What two factors cause action potentials to vary?

    <p>speed, frequency</p> Signup and view all the answers

    The insulating coating on axons that helps to increase transmission speed is called the ______ sheath.

    <p>myelin</p> Signup and view all the answers

    Which of the following best describes saltatory conduction?

    <p>The 'leaping' of action potentials from one Node of Ranvier to the next along a myelinated axon. (A)</p> Signup and view all the answers

    Flashcards

    Neurons

    Cells that transmit electrical impulses in the body.

    Action potential

    An electrical impulse sent along a neuron's axon when stimulated.

    Electrical impulse

    A quick change in electrical charge that travels along a neuron.

    Axon

    The long part of a neuron that carries impulses away from the cell body.

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    Frequency of pulses

    The number of action potentials sent by a neuron in a given time.

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    Neurotransmission

    The process of communication between neurons using action potentials.

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    Positive and negative charges

    The electrical properties of materials that affect neuron activity.

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    Membranes in neurons

    Barriers that keep positive and negative charges separate in neurons.

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    Sack of batteries analogy

    Compares the body to a battery storing electrical potential.

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    Binary code in the brain

    The way the brain interprets signals from neurons based on their patterns.

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    Depolarization

    The process where the inside of a neuron becomes more positive than its resting state, typically reaching +40 mV.

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    Resting Membrane Potential

    The voltage across a neuron's membrane at rest, typically around -70 mV.

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    Repolarization

    The phase following depolarization where potassium ions exit the neuron to restore negative internal charge.

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    Hyperpolarization

    A phase where the membrane potential becomes more negative than the resting potential, usually around -75 mV.

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    Refractory Period

    The time during which a neuron cannot fire again immediately after an action potential, ensuring signal directionality.

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    Threshold Potential

    The membrane voltage that must be reached for an action potential to occur; typically about -55 mV.

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    Nodes of Ranvier

    Gaps in the myelin sheath where action potentials are regenerated, allowing faster signal conduction.

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    Saltatory Conduction

    The process by which action potentials jump from one Node of Ranvier to another, speeding up impulse transmission.

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    Frequency of Action Potentials

    The rate at which action potentials occur, increasing with the strength of a stimulus.

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    Membrane Potential

    The difference in charge inside and outside a neuron.

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    Sodium-Potassium Pump

    A protein that pumps sodium out and potassium into the neuron.

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    Electrochemical Gradient

    The difference in concentration and charge across a membrane.

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    Graded Potential

    A small change in membrane potential caused by few ion channels opening.

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    Voltage-Gated Channels

    Ion channels that open at specific membrane potentials.

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    Ligand-Gated Channels

    Ion channels that open when a specific molecule binds.

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    Mechanically-Gated Channels

    Ion channels that open in response to physical stretching.

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    Study Notes

    Neurons and Action Potentials

    • Neurons communicate using electrical impulses, called action potentials, which travel down the axon to neighboring neurons.
    • The signal strength and speed are constant; however, the frequency of the impulses varies, allowing the brain to translate different signals.
    • The brain interprets these signals based on their location, sensation, magnitude, and importance.

    Neurons as Batteries

    • The body is electrically neutral, with equal positive and negative charges.
    • Membranes create barriers to keep charges separate to "build potential".
    • Neurons function like tiny batteries, holding separated charges that need a trigger to release energy.

    Electrical Concepts in Neurons

    • Voltage: Measures the potential energy of separated charges in millivolts (mV).
    • Membrane potential: The difference in charge across a cell membrane. Higher voltage = higher potential.
    • Current: The flow of electricity; influenced by voltage and resistance.
    • Resistance: Anything hindering current flow (insulators like plastic). Low resistance = conductors (metal).
    • Neurons use ion currents (movement of charged ions) across membranes.

    Resting Membrane Potential

    • A resting neuron is more negative inside than outside (-70mV).
    • This is the resting membrane potential.
    • Positive sodium ions gather outside the membrane; potassium ions are inside, mixed with negative proteins.

    Sodium-Potassium Pump

    • The sodium-potassium pump maintains the ion concentration differences, making the outside of the cell more positive.
    • It pumps 3 sodium ions out and 2 potassium ions in per cycle.
    • This creates an electrochemical gradient that causes ions to move across the membrane.

    Ion Channels

    • The membrane is filled with ion channels that open and close to allow ions to pass.
    • Voltage-gated: Open/close based on membrane voltage; crucial for action potentials.
    • Ligand-gated: Open when a neurotransmitter attaches; involved in signal transmission.
    • Mechanically-gated: Open in response to mechanical force.

    Graded Potential vs. Action Potential

    • Graded potential: Small, localized changes in membrane potential; not strong enough for long-distance signals.
    • Action potential: Large change in membrane potential, triggering a chain reaction down the axon; fundamental for long-distance communication.
    • Action potential must exceed a threshold voltage (-55mV) to trigger.

    Depolarization

    • Neuron at rest (-70mV).
    • Stimulus triggers voltage-gated sodium channels to open.
    • Sodium rushes into the cell, making the inside more positive (+40mV).
    • This is depolarization.

    Repolarization

    • Voltage-gated potassium channels open, letting potassium flow out.
    • Charges reverse back toward rest.

    Hyperpolarization

    • Potassium channels stay open slightly longer, undershooting resting potential (-75mV).
    • Sodium-potassium pumps restore resting potential.

    Refractory Period

    • An axon undergoing an action potential can't respond to another stimulus.
    • Prevents signals from traveling in both directions.

    Action Potential Properties

    • All-or-nothing phenomenon: reaching the threshold triggers an action potential; weaker stimulus yields no response.
    • Frequency of action potentials varies based on the intensity of the stimulus.
    • Speed of action potential varies, faster in myelinated axons (saltatory conduction). Myelin insulates axons, leaping over gaps called the Nodes of Ranvier.

    Conduction Velocity

    • Speed of action potential propagation; determined by myelination.

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    Description

    Explore the fascinating world of neurons and action potentials in this quiz. Understand how neurons communicate through electrical impulses and learn the principles of voltage, membrane potential, and electrical concepts. Test your knowledge on how these elements affect brain function and signal interpretation.

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